| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.369447 |
| EZR | ezrin | 0.143724 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.08745 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0855291 |
| PKM | pyruvate kinase, muscle | 0.0851102 |
| TJP1 | tight junction protein 1 | 0.081938 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0817246 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0787551 |
| DSPP | dentin sialophosphoprotein | 0.0785854 |
| KRT20 | keratin 20, type I | 0.0774403 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0773019 |
| ENO1 | enolase 1, (alpha) | 0.0766054 |
| PLK2 | polo-like kinase 2 | 0.0765598 |
| SMAD3 | SMAD family member 3 | 0.0744193 |
| FAT1 | FAT atypical cadherin 1 | 0.0737172 |
| DST | dystonin | 0.0726833 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.068779 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.068683 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0666709 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0638875 |
| RPS3 | ribosomal protein S3 | 0.0631414 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0627957 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0620405 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.059623 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0594226 |
| CALR | calreticulin | 0.0575802 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.055331 |
| MYO5B | myosin VB | 0.0540852 |
| NTN4 | netrin 4 | 0.0533842 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0533253 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0519508 |
| RND3 | Rho family GTPase 3 | 0.0518454 |
| TMC5 | transmembrane channel-like 5 | 0.0513302 |
| JUN | jun proto-oncogene | 0.0509668 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0505065 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0504622 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0503669 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0500577 |
| EMP1 | epithelial membrane protein 1 | 0.0499811 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0491111 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0490012 |
| CTBP2 | C-terminal binding protein 2 | 0.0475761 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0471417 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0451118 |
| KRT18 | keratin 18, type I | 0.0448181 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0448027 |
| PDZD8 | PDZ domain containing 8 | 0.0445979 |
| ANXA11 | annexin A11 | 0.0445265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0428153 |
| MYO6 | myosin VI | 0.0427197 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.042485 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0422749 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0414478 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0407204 |
| RPL4 | ribosomal protein L4 | 0.0406468 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0400267 |
| ETV6 | ets variant 6 | 0.0397297 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0387351 |
| ITPKC | inositol-trisphosphate 3-kinase C | 0.0386447 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0386035 |
| CD164 | CD164 molecule, sialomucin | 0.0381147 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0372689 |
| RPS12 | ribosomal protein S12 | 0.0369758 |
| RPL41 | ribosomal protein L41 | 0.0362794 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0361982 |
| UTRN | utrophin | 0.0358315 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0357418 |
| BPTF | bromodomain PHD finger transcription factor | 0.0354337 |
| HYOU1 | hypoxia up-regulated 1 | 0.0354165 |
| NEBL | nebulette | 0.0353966 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.035013 |
| TPM3 | tropomyosin 3 | 0.0348567 |
| AFDN | afadin, adherens junction formation factor | 0.0344564 |
| EPS8L1 | EPS8-like 1 | 0.0340307 |
| EXPH5 | exophilin 5 | 0.0339024 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0334045 |
| TMEM45B | transmembrane protein 45B | 0.0332843 |
| LDHA | lactate dehydrogenase A | 0.0329017 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0328301 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0327924 |
| SEPTIN9 | septin 9 | 0.0327319 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0326194 |
| OCLN | occludin | 0.0322273 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0320573 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0319862 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0315743 |
| PPL | periplakin | 0.0314313 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0313667 |
| STK24 | serine/threonine kinase 24 | 0.0313374 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0312862 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.031202 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0311665 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 | 0.0311526 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0309896 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0308379 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0308055 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.030764 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0307567 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0307549 |
| POF1B | premature ovarian failure, 1B | 0.0305266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105104 |
| NDRG1 | N-myc downstream regulated 1 | -0.101891 |
| TXNRD1 | thioredoxin reductase 1 | -0.100695 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0903685 |
| LYZ | lysozyme | -0.0634849 |
| ANXA2 | annexin A2 | -0.0632859 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0624832 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0605987 |
| TMSB10 | thymosin beta 10 | -0.0604723 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0578998 |
| VCL | vinculin | -0.0570471 |
| EGR1 | early growth response 1 | -0.0553061 |
| ACTN4 | actinin, alpha 4 | -0.0545242 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0542694 |
| HM13 | histocompatibility (minor) 13 | -0.0537494 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0512104 |
| PTMA | prothymosin, alpha | -0.049224 |
| ACTG1 | actin gamma 1 | -0.0470001 |
| DIAPH2 | diaphanous-related formin 2 | -0.0467697 |
| WASF2 | WAS protein family, member 2 | -0.0459825 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0454146 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0452551 |
| HMGA1 | high mobility group AT-hook 1 | -0.0444116 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0417845 |
| RPL21 | ribosomal protein L21 | -0.0415402 |
| RBM39 | RNA binding motif protein 39 | -0.0398658 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0379381 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0378062 |
| INTS6 | integrator complex subunit 6 | -0.0374076 |
| NF1 | neurofibromin 1 | -0.0370741 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0358994 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0358803 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0350932 |
| GNAS | GNAS complex locus | -0.033835 |
| COG5 | component of oligomeric golgi complex 5 | -0.0338305 |
| FOSL1 | FOS-like antigen 1 | -0.0321404 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0321199 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0316404 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0315707 |
| LAMA4 | laminin, alpha 4 | -0.0307173 |
| RTN4 | reticulon 4 | -0.0306891 |
| FRY | furry homolog (Drosophila) | -0.030462 |
| AGR2 | anterior gradient 2 | -0.0303364 |
| DSTN | destrin (actin depolymerizing factor) | -0.0301236 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.029956 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0297221 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0285205 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0276465 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0271486 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0269084 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.026864 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0268056 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0265617 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0264745 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0263823 |
| INSIG1 | insulin induced gene 1 | -0.0261605 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0260334 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0259821 |
| RPS24 | ribosomal protein S24 | -0.0259286 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0258935 |
| ZNF207 | zinc finger protein 207 | -0.0254957 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0254777 |
| IL6ST | interleukin 6 signal transducer | -0.0252911 |
| ADIPOR2 | adiponectin receptor 2 | -0.0252857 |
| FOXO3 | forkhead box O3 | -0.0252453 |
| GPX2 | glutathione peroxidase 2 | -0.0250975 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0250862 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0250515 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.0248331 |
| KLHL24 | kelch-like family member 24 | -0.0245365 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0244061 |
| SBF2 | SET binding factor 2 | -0.024399 |
| CHKA | choline kinase alpha | -0.0243943 |
| RPS23 | ribosomal protein S23 | -0.0241736 |
| RTN3 | reticulon 3 | -0.0241571 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | -0.0240187 |
| RPL28 | ribosomal protein L28 | -0.0239437 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0238448 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.023605 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0233971 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0233264 |
| RPS25 | ribosomal protein S25 | -0.023322 |
| FNIP1 | folliculin interacting protein 1 | -0.0230704 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0230336 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0229836 |
| KRT8 | keratin 8, type II | -0.0229136 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0228154 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0225971 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0225021 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0224843 |
| ARF4 | ADP-ribosylation factor 4 | -0.0223722 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0223668 |
| LNX2 | ligand of numb-protein X 2 | -0.0222678 |
| SERTAD2 | SERTA domain containing 2 | -0.0220191 |
| SQSTM1 | sequestosome 1 | -0.0219924 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | -0.0219621 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0219584 |
| NPSR1 | neuropeptide S receptor 1 | -0.0218902 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0217619 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0216535 |
