| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.245146 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.171353 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.156242 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.114012 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.111603 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.10732 |
| ATXN1 | ataxin 1 | 0.103142 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0965897 |
| SVIL | supervillin | 0.0953813 |
| DSPP | dentin sialophosphoprotein | 0.0767683 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.076111 |
| C3 | complement component 3 | 0.0744374 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0744231 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.069772 |
| ASPH | aspartate beta-hydroxylase | 0.0617896 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0592294 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0560376 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0554321 |
| FAT1 | FAT atypical cadherin 1 | 0.0550886 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0536681 |
| SMAD3 | SMAD family member 3 | 0.0533288 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0523864 |
| KYNU | kynureninase | 0.0518499 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0499312 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0496723 |
| FAM107B | family with sequence similarity 107, member B | 0.0491884 |
| INTS6 | integrator complex subunit 6 | 0.0469945 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0463339 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0439838 |
| FOXP1 | forkhead box P1 | 0.0439769 |
| AFDN | afadin, adherens junction formation factor | 0.0430613 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0406945 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0403347 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0400032 |
| MT2A | metallothionein 2A | 0.0393754 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0380702 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0375336 |
| DST | dystonin | 0.0374678 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0369607 |
| TLE4 | transducin-like enhancer of split 4 | 0.0364947 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | 0.0357854 |
| HPCAL1 | hippocalcin-like 1 | 0.0350956 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0345549 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0333489 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0329789 |
| RASA2 | RAS p21 protein activator 2 | 0.0329033 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0326314 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0322465 |
| JAG1 | jagged 1 | 0.0313694 |
| BCL2L1 | BCL2-like 1 | 0.0312287 |
| USP34 | ubiquitin specific peptidase 34 | 0.0308692 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0306114 |
| ITGB5 | integrin, beta 5 | 0.0305054 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0303794 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0303284 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0303254 |
| FERMT2 | fermitin family member 2 | 0.0299104 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0284287 |
| MCL1 | myeloid cell leukemia 1 | 0.0283545 |
| MYO1B | myosin IB | 0.0282766 |
| DIAPH1 | diaphanous-related formin 1 | 0.0282599 |
| VEGFA | vascular endothelial growth factor A | 0.0278782 |
| RPS12 | ribosomal protein S12 | 0.027769 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0277137 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0274858 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0274175 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0272814 |
| JAK1 | Janus kinase 1 | 0.0271158 |
| RPL3 | ribosomal protein L3 | 0.026947 |
| SERTAD2 | SERTA domain containing 2 | 0.0268194 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0267079 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.026219 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0259014 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0255884 |
| MYO1E | myosin IE | 0.0253546 |
| CORO1C | coronin, actin binding protein, 1C | 0.0252103 |
| POTEF | POTE ankyrin domain family, member F | 0.0250977 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0248806 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0244915 |
| USP47 | ubiquitin specific peptidase 47 | 0.0243258 |
| VMP1 | vacuole membrane protein 1 | 0.0242013 |
| KIAA1217 | KIAA1217 | 0.0241492 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0239279 |
| HOMER1 | homer scaffolding protein 1 | 0.0238137 |
| SEPTIN9 | septin 9 | 0.0238132 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0237667 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0237443 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0236948 |
| HDAC4 | histone deacetylase 4 | 0.0234794 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0233035 |
| ZNF638 | zinc finger protein 638 | 0.0232203 |
| TNS1 | tensin 1 | 0.0231657 |
| WWC2 | WW and C2 domain containing 2 | 0.0230421 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0227569 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0225463 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0224929 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0224922 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0222969 |
| KIF21A | kinesin family member 21A | 0.0221905 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.022179 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.32526 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.119839 |
| GPC3 | glypican 3 | -0.0998283 |
| CP | ceruloplasmin (ferroxidase) | -0.0917578 |
| APOA2 | apolipoprotein A-II | -0.0909733 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0906422 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0797821 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0768258 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0693852 |
| EHBP1 | EH domain binding protein 1 | -0.0680495 |
| TRIM26 | tripartite motif containing 26 | -0.0663814 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0660236 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0658149 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.061715 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0598301 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | -0.0585481 |
| TMEM123 | transmembrane protein 123 | -0.0584158 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0531253 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0526481 |
| A2M | alpha-2-macroglobulin | -0.05054 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0491735 |
| LYZ | lysozyme | -0.0471373 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0436095 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0434054 |
| PEG3 | paternally expressed 3 | -0.0420904 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.041251 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0405046 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.0392092 |
| FTL | ferritin, light polypeptide | -0.0381161 |
| RBM39 | RNA binding motif protein 39 | -0.0371776 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0364011 |
| AMBP | alpha-1-microglobulin/bikunin precursor | -0.0362917 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0350465 |
| NPR2 | natriuretic peptide receptor 2 | -0.0350096 |
| APOE | apolipoprotein E | -0.0339885 |
| TPM4 | tropomyosin 4 | -0.0325026 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.031256 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | -0.0309271 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0305224 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0299743 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0293795 |
| PDGFB | platelet-derived growth factor beta polypeptide | -0.0283535 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | -0.0283079 |
| PERP | PERP, TP53 apoptosis effector | -0.0282256 |
| KPNB1 | karyopherin (importin) beta 1 | -0.027443 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0273577 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0268625 |
| GNAS | GNAS complex locus | -0.0267789 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | -0.0264968 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0264374 |
| GDF15 | growth differentiation factor 15 | -0.0264277 |
| ITGA1 | integrin, alpha 1 | -0.026158 |
| DOK6 | docking protein 6 | -0.0259016 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0251686 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0245224 |
| EGR1 | early growth response 1 | -0.0243516 |
| ATP10A | ATPase, class V, type 10A | -0.023846 |
| B2M | beta-2-microglobulin | -0.0235071 |
| IER3 | immediate early response 3 | -0.0234694 |
| GK | glycerol kinase | -0.0230972 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | -0.0230566 |
| RUNX1 | runt-related transcription factor 1 | -0.0229687 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.022935 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0226251 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0226021 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0224365 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0224291 |
| RPS24 | ribosomal protein S24 | -0.022399 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0213262 |
| FERMT1 | fermitin family member 1 | -0.0213088 |
| ESF1 | ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) | -0.0212612 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0211879 |
| CALD1 | caldesmon 1 | -0.0210402 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.021024 |
| EPCAM | epithelial cell adhesion molecule | -0.0209375 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0206192 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0205687 |
| MX2 | MX dynamin-like GTPase 2 | -0.0205085 |
| PLIN2 | perilipin 2 | -0.0205027 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0204069 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.019929 |
| SCN1A | sodium channel, voltage gated, type I alpha subunit | -0.0199131 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0198549 |
| JUN | jun proto-oncogene | -0.0198425 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0197308 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | -0.019671 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | -0.0195849 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0193867 |
| PHF21A | PHD finger protein 21A | -0.0193756 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 | -0.0192215 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0191497 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0190946 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0190895 |
| WDR45B | WD repeat domain 45B | -0.0190568 |
| JMJD1C | jumonji domain containing 1C | -0.0190298 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.018789 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0187635 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0187583 |
| LAMA4 | laminin, alpha 4 | -0.018652 |
| CRY1 | cryptochrome circadian clock 1 | -0.018341 |
