| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.170748 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0992865 |
| MT2A | metallothionein 2A | 0.0908245 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0874171 |
| ASPH | aspartate beta-hydroxylase | 0.0635754 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0610573 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0606835 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0603959 |
| JAG1 | jagged 1 | 0.0519748 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0507362 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0494078 |
| RPS6 | ribosomal protein S6 | 0.0482515 |
| BARX2 | BARX homeobox 2 | 0.0459086 |
| MT1X | metallothionein 1X | 0.0443642 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.0406494 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0398814 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0397907 |
| DOK5 | docking protein 5 | 0.0388324 |
| B2M | beta-2-microglobulin | 0.0383682 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0379369 |
| RPL34 | ribosomal protein L34 | 0.0379138 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0377336 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0376876 |
| RPL35A | ribosomal protein L35a | 0.0361342 |
| CSMD2 | CUB and Sushi multiple domains 2 | 0.0355173 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0354857 |
| DST | dystonin | 0.0349497 |
| RPL37 | ribosomal protein L37 | 0.0347931 |
| MT1E | metallothionein 1E | 0.034633 |
| FN1 | fibronectin 1 | 0.0343735 |
| RPL11 | ribosomal protein L11 | 0.0341318 |
| GRAMD1B | GRAM domain containing 1B | 0.0339436 |
| FTL | ferritin, light polypeptide | 0.0339091 |
| RPS3 | ribosomal protein S3 | 0.0336477 |
| RPL12 | ribosomal protein L12 | 0.0334462 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0332522 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0327893 |
| RPS8 | ribosomal protein S8 | 0.0324633 |
| RPL9 | ribosomal protein L9 | 0.0321608 |
| TGM2 | transglutaminase 2 | 0.0320532 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0320282 |
| INTS6 | integrator complex subunit 6 | 0.0319795 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0315583 |
| HMGA2 | high mobility group AT-hook 2 | 0.0314155 |
| TMSB4X | thymosin beta 4, X-linked | 0.0314128 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0307834 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0307542 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0305431 |
| POTEF | POTE ankyrin domain family, member F | 0.030405 |
| AOPEP | aminopeptidase O (putative) | 0.0302318 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0293384 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0291383 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0288599 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0288121 |
| FAM107B | family with sequence similarity 107, member B | 0.0282395 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0280805 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0277892 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0277307 |
| RPL26 | ribosomal protein L26 | 0.0275951 |
| RPLP2 | ribosomal protein, large, P2 | 0.0272119 |
| RPL37A | ribosomal protein L37a | 0.0271865 |
| ARRDC3 | arrestin domain containing 3 | 0.0270063 |
| RPS14 | ribosomal protein S14 | 0.0269913 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0269263 |
| RAD51B | RAD51 paralog B | 0.0268908 |
| RPS19 | ribosomal protein S19 | 0.0267348 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0259283 |
| PALLD | palladin, cytoskeletal associated protein | 0.0256505 |
| FRMD6 | FERM domain containing 6 | 0.0252809 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0252122 |
| RPS12 | ribosomal protein S12 | 0.0251888 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0249102 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0247219 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0246813 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0245601 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0240719 |
| RPS24 | ribosomal protein S24 | 0.0240384 |
| RPL30 | ribosomal protein L30 | 0.0236128 |
| RPS27 | ribosomal protein S27 | 0.0233073 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0229201 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0228079 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0227996 |
| RPS4X | ribosomal protein S4, X-linked | 0.0222717 |
| RPS25 | ribosomal protein S25 | 0.0222406 |
| RPL23 | ribosomal protein L23 | 0.0222005 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0220887 |
| RPS17 | ribosomal protein S17 | 0.0219995 |
| RPLP0 | ribosomal protein, large, P0 | 0.0216954 |
| MT1G | metallothionein 1G | 0.0216584 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.021435 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0212938 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0212296 |
| TXNIP | thioredoxin interacting protein | 0.0208018 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0207073 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0206467 |
| ITGB8 | integrin, beta 8 | 0.0205487 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0203721 |
| ATXN1 | ataxin 1 | 0.0200569 |
| VEGFA | vascular endothelial growth factor A | 0.0199765 |
| CALCRL | calcitonin receptor-like | 0.019962 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.311583 |
| FLNB | filamin B, beta | -0.220963 |
| AHNAK | AHNAK nucleoprotein | -0.190236 |
| EMP1 | epithelial membrane protein 1 | -0.146475 |
| ANXA2 | annexin A2 | -0.110173 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0925119 |
| NDRG1 | N-myc downstream regulated 1 | -0.0916742 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0885752 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0865002 |
| LAMC2 | laminin, gamma 2 | -0.0816648 |
| SULF1 | sulfatase 1 | -0.0805787 |
| MTSS1 | metastasis suppressor 1 | -0.0762043 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0728982 |
| EZR | ezrin | -0.0689753 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0670471 |
| ACTN4 | actinin, alpha 4 | -0.0612385 |
| BCL2L1 | BCL2-like 1 | -0.0612299 |
| RBM39 | RNA binding motif protein 39 | -0.0603403 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0600864 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0587677 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0587363 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0581175 |
| CALU | calumenin | -0.057105 |
| KRT17 | keratin 17, type I | -0.0564678 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0562361 |
| RIGI | RNA sensor RIG-I | -0.0561911 |
| LMNA | lamin A/C | -0.0553167 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0542365 |
| LDLR | low density lipoprotein receptor | -0.0528833 |
| CLIC4 | chloride intracellular channel 4 | -0.0522792 |
| TPM4 | tropomyosin 4 | -0.0515644 |
| FOSL1 | FOS-like antigen 1 | -0.0515046 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0503106 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0497592 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0487359 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.048108 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0477875 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0461043 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0457494 |
| PTMA | prothymosin, alpha | -0.0451126 |
| H1-0 | H1.0 linker histone | -0.0450972 |
| EGR1 | early growth response 1 | -0.0430078 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0428496 |
| MECOM | MDS1 and EVI1 complex locus | -0.0423179 |
| CLU | clusterin | -0.0422017 |
| GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | -0.0419959 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0410069 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0409254 |
| ANLN | anillin, actin binding protein | -0.0409142 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0407378 |
| HLA-E | major histocompatibility complex, class I, E | -0.0405594 |
| GNAS | GNAS complex locus | -0.0401979 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0401527 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0401033 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0397747 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0394866 |
| UBC | ubiquitin C | -0.0394155 |
| ITGA6 | integrin, alpha 6 | -0.0388323 |
| NF1 | neurofibromin 1 | -0.0378719 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0378062 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0377109 |
| ANXA1 | annexin A1 | -0.0374015 |
| FOXO1 | forkhead box O1 | -0.0369425 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0369028 |
| HM13 | histocompatibility (minor) 13 | -0.0367879 |
| ARCN1 | archain 1 | -0.0367213 |
| SQLE | squalene epoxidase | -0.0362966 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0362079 |
| GOLGA4 | golgin A4 | -0.0360848 |
| NAV2 | neuron navigator 2 | -0.0359524 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0349537 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0346922 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 | -0.0346406 |
| CD99 | CD99 molecule | -0.0345942 |
| COL17A1 | collagen, type XVII, alpha 1 | -0.034471 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0341648 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0341324 |
| NEK7 | NIMA-related kinase 7 | -0.0337664 |
| MKI67 | marker of proliferation Ki-67 | -0.0333162 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.032899 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0326959 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0322883 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0321856 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0319861 |
| TMEM135 | transmembrane protein 135 | -0.0316821 |
| DSG2 | desmoglein 2 | -0.031249 |
| RCOR1 | REST corepressor 1 | -0.0312148 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0308136 |
| RHEB | Ras homolog enriched in brain | -0.0306921 |
| CAVIN1 | caveolae associated protein 1 | -0.0305871 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0304989 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0304176 |
| MEIS2 | Meis homeobox 2 | -0.0301989 |
| SERINC3 | serine incorporator 3 | -0.0298824 |
| MEF2A | myocyte enhancer factor 2A | -0.0296386 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0295454 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0295429 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0291959 |
| TXNRD1 | thioredoxin reductase 1 | -0.0289617 |
| KRT14 | keratin 14, type I | -0.0289303 |
