| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.439622 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.180971 |
| MT2A | metallothionein 2A | 0.137847 |
| ENO1 | enolase 1, (alpha) | 0.129971 |
| ZNF841 | zinc finger protein 841 | 0.114863 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.105519 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0969399 |
| DST | dystonin | 0.0746621 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0703491 |
| PODXL | podocalyxin-like | 0.0624094 |
| LDHA | lactate dehydrogenase A | 0.056911 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0559369 |
| MT1X | metallothionein 1X | 0.0523607 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0514198 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.05027 |
| TPM3 | tropomyosin 3 | 0.0487161 |
| PKM | pyruvate kinase, muscle | 0.044492 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.04407 |
| CD44 | CD44 molecule (Indian blood group) | 0.0428146 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0402752 |
| ASPH | aspartate beta-hydroxylase | 0.0396898 |
| RPS3 | ribosomal protein S3 | 0.0396076 |
| CALR | calreticulin | 0.0378712 |
| ERBIN | erbb2 interacting protein | 0.036185 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0359847 |
| CENPF | centromere protein F, 350/400kDa | 0.0355475 |
| HEG1 | heart development protein with EGF-like domains 1 | 0.0341261 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0330889 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0324109 |
| ADM | adrenomedullin | 0.0315595 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0306929 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0304973 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.030175 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0301425 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0295879 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0292988 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0287114 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0285497 |
| HMGB2 | high mobility group box 2 | 0.0284515 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0283639 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0275599 |
| TPR | translocated promoter region, nuclear basket protein | 0.0271699 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0268211 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0265146 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0263846 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0262309 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0260634 |
| EZR | ezrin | 0.0258998 |
| APP | amyloid beta (A4) precursor protein | 0.0248118 |
| ANGPTL4 | angiopoietin-like 4 | 0.0241634 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0240906 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.023896 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0238884 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0233525 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0228908 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0228828 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0225002 |
| ACTN1 | actinin, alpha 1 | 0.0224826 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0224 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0223495 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0221312 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0220802 |
| SET | SET nuclear proto-oncogene | 0.0220225 |
| SEPTIN9 | septin 9 | 0.0219916 |
| RPS12 | ribosomal protein S12 | 0.0219658 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.021925 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0217734 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0217589 |
| RPS2 | ribosomal protein S2 | 0.0215441 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0212741 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0211685 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0211294 |
| MSN | moesin | 0.0210928 |
| ATP13A3 | ATPase type 13A3 | 0.0206571 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0206321 |
| LMO7 | LIM domain 7 | 0.0203029 |
| TXNRD1 | thioredoxin reductase 1 | 0.0202582 |
| POTEF | POTE ankyrin domain family, member F | 0.020166 |
| EFNA5 | ephrin-A5 | 0.0199524 |
| MCL1 | myeloid cell leukemia 1 | 0.0195462 |
| RPL41 | ribosomal protein L41 | 0.0190753 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0190516 |
| RPL26 | ribosomal protein L26 | 0.0189742 |
| SMAD3 | SMAD family member 3 | 0.0185734 |
| TMSB4X | thymosin beta 4, X-linked | 0.0184271 |
| MYO10 | myosin X | 0.0182267 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0181948 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0181809 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.018021 |
| JUN | jun proto-oncogene | 0.0179294 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0178646 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0177339 |
| LIMA1 | LIM domain and actin binding 1 | 0.0176878 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0176639 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.0175611 |
| INTS6 | integrator complex subunit 6 | 0.0175557 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0175479 |
| YBX1 | Y box binding protein 1 | 0.017415 |
| ANXA2 | annexin A2 | 0.017405 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0172085 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.224853 |
| HLA-B | major histocompatibility complex, class I, B | -0.209573 |
| FN1 | fibronectin 1 | -0.193964 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.148015 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.125452 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.111795 |
| FTL | ferritin, light polypeptide | -0.106003 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0899095 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0796446 |
| DEK | DEK proto-oncogene | -0.073578 |
| GLIS3 | GLIS family zinc finger 3 | -0.0537179 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0534765 |
| SLC12A8 | solute carrier family 12, member 8 | -0.0497307 |
| PTMA | prothymosin, alpha | -0.0480733 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0467484 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0425301 |
| ZXDC | ZXD family zinc finger C | -0.0413971 |
| VIM | vimentin | -0.0413753 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0411278 |
| ACTG1 | actin gamma 1 | -0.0398925 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0388169 |
| POSTN | periostin, osteoblast specific factor | -0.0385212 |
| CTSD | cathepsin D | -0.0384277 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0383248 |
| CCBE1 | collagen and calcium binding EGF domains 1 | -0.0375804 |
| PLCB4 | phospholipase C, beta 4 | -0.0367966 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0366223 |
| RPS6 | ribosomal protein S6 | -0.0351735 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0349225 |
| NDRG1 | N-myc downstream regulated 1 | -0.0348636 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0331564 |
| CCND1 | cyclin D1 | -0.0328155 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0327222 |
| RPLP2 | ribosomal protein, large, P2 | -0.0326429 |
| S100A10 | S100 calcium binding protein A10 | -0.0325764 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0314489 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0310367 |
| ARF4 | ADP-ribosylation factor 4 | -0.0306561 |
| KRT7 | keratin 7, type II | -0.0302823 |
| SULF1 | sulfatase 1 | -0.0294501 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0293394 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0290544 |
| TMSB10 | thymosin beta 10 | -0.0288485 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0286267 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0277535 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0274351 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0268356 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0265966 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0264989 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0264821 |
| RPS23 | ribosomal protein S23 | -0.0260903 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | -0.0260538 |
| OSMR | oncostatin M receptor | -0.0256665 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0256228 |
| MMP12 | matrix metallopeptidase 12 | -0.0254073 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0252549 |
| MAP1B | microtubule-associated protein 1B | -0.0250816 |
| AHNAK | AHNAK nucleoprotein | -0.0249602 |
| PTK2 | protein tyrosine kinase 2 | -0.0248411 |
| ZNF804A | zinc finger protein 804A | -0.024819 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0247483 |
| FOXP1 | forkhead box P1 | -0.0247364 |
| SBF2 | SET binding factor 2 | -0.0246349 |
| RPL28 | ribosomal protein L28 | -0.0244348 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0243377 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0242789 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0242263 |
| PFN1 | profilin 1 | -0.0239175 |
| RBM39 | RNA binding motif protein 39 | -0.0238862 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0237122 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0230998 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.0229803 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0227823 |
| ZNF609 | zinc finger protein 609 | -0.022702 |
| MTDH | metadherin | -0.0222773 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0220789 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0220654 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0218841 |
| RPL7A | ribosomal protein L7a | -0.0218696 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0216798 |
| RPL21 | ribosomal protein L21 | -0.0216537 |
| TMEM178B | transmembrane protein 178B | -0.0215974 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0214787 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.021437 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0213346 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0211075 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0210962 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0210355 |
| RPLP1 | ribosomal protein, large, P1 | -0.0210034 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0210004 |
| GNAS | GNAS complex locus | -0.0209376 |
| HLA-E | major histocompatibility complex, class I, E | -0.0206665 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0203729 |
| EGR1 | early growth response 1 | -0.0200919 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0200059 |
| CCDC80 | coiled-coil domain containing 80 | -0.0199277 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0198627 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0198043 |
| TUBB4B | tubulin, beta 4B class IVb | -0.019482 |
| TRIM56 | tripartite motif containing 56 | -0.0194322 |
