| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSPP | dentin sialophosphoprotein | 0.171523 |
| EZR | ezrin | 0.131294 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.123727 |
| RPS12 | ribosomal protein S12 | 0.0947803 |
| LMO7 | LIM domain 7 | 0.0732277 |
| RPS3 | ribosomal protein S3 | 0.0725354 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0704393 |
| RPL41 | ribosomal protein L41 | 0.0687625 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0652869 |
| PKM | pyruvate kinase, muscle | 0.0648576 |
| RPL4 | ribosomal protein L4 | 0.0639385 |
| CANX | calnexin | 0.0625768 |
| ENO1 | enolase 1, (alpha) | 0.0583448 |
| FAT1 | FAT atypical cadherin 1 | 0.0545464 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0544317 |
| LAMB3 | laminin, beta 3 | 0.0535361 |
| MUC13 | mucin 13, cell surface associated | 0.0495856 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0489697 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0461249 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0447415 |
| ASPH | aspartate beta-hydroxylase | 0.0445078 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0425154 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0418507 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0408952 |
| SERINC5 | serine incorporator 5 | 0.0407357 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0391022 |
| AFDN | afadin, adherens junction formation factor | 0.0384153 |
| SLTM | SAFB-like, transcription modulator | 0.0360441 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0350491 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0346259 |
| LDHA | lactate dehydrogenase A | 0.0330648 |
| DST | dystonin | 0.0314917 |
| PGK1 | phosphoglycerate kinase 1 | 0.0308026 |
| AHNAK | AHNAK nucleoprotein | 0.0306577 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0303447 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0299055 |
| CALR | calreticulin | 0.0297873 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0296392 |
| RPL26 | ribosomal protein L26 | 0.0281409 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0277194 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0275515 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.027483 |
| SLK | STE20-like kinase | 0.0274701 |
| SPON1 | spondin 1, extracellular matrix protein | 0.0271289 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.02664 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0264018 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0262008 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0256365 |
| TMSB4X | thymosin beta 4, X-linked | 0.0255159 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0248935 |
| RPL14 | ribosomal protein L14 | 0.0247275 |
| FMNL2 | formin-like 2 | 0.0235992 |
| TPR | translocated promoter region, nuclear basket protein | 0.0235917 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0234343 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0232977 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.023224 |
| CLTC | clathrin, heavy chain (Hc) | 0.0231943 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0230793 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0229783 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0228619 |
| CD164 | CD164 molecule, sialomucin | 0.0227423 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.022564 |
| EHF | ets homologous factor | 0.0223886 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0218466 |
| TPM3 | tropomyosin 3 | 0.0216174 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0215995 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0215946 |
| MSI2 | musashi RNA-binding protein 2 | 0.0215533 |
| INTS6 | integrator complex subunit 6 | 0.0215471 |
| RIMKLB | ribosomal modification protein rimK-like family member B | 0.0214557 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0213849 |
| LOC105378220 | macrophage receptor MARCO-like | 0.0207362 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0207199 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0206557 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0197684 |
| CAPRIN2 | caprin family member 2 | 0.0197663 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0194221 |
| PDLIM5 | PDZ and LIM domain 5 | 0.019273 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0191162 |
| TMF1 | TATA element modulatory factor 1 | 0.0187148 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.0186783 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0186031 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0185065 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.018506 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0184917 |
| MYO6 | myosin VI | 0.0184019 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0183866 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0183624 |
| RPS2 | ribosomal protein S2 | 0.0182254 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0180119 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0179833 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0178225 |
| MYO5B | myosin VB | 0.0177567 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0176905 |
| CD9 | CD9 molecule | 0.0176427 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0174081 |
| ATP10B | ATPase, class V, type 10B | 0.0173515 |
| APP | amyloid beta (A4) precursor protein | 0.0173289 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0173161 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0172095 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.291786 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.160845 |
| RPS6 | ribosomal protein S6 | -0.146861 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.122891 |
| RPS23 | ribosomal protein S23 | -0.112635 |
| RPLP1 | ribosomal protein, large, P1 | -0.110446 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0993468 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0964328 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0886076 |
| TMSB10 | thymosin beta 10 | -0.0879845 |
| RPLP0 | ribosomal protein, large, P0 | -0.0867243 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.083504 |
| POTEF | POTE ankyrin domain family, member F | -0.0827152 |
| RPS25 | ribosomal protein S25 | -0.0822286 |
| ACTG1 | actin gamma 1 | -0.0730364 |
| RPS24 | ribosomal protein S24 | -0.068834 |
| RPS16 | ribosomal protein S16 | -0.0643518 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0634051 |
| HLA-B | major histocompatibility complex, class I, B | -0.0633272 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0581252 |
| RPS15 | ribosomal protein S15 | -0.0568839 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0560715 |
| RPL28 | ribosomal protein L28 | -0.0559096 |
| HMGA1 | high mobility group AT-hook 1 | -0.0558185 |
| RPL9 | ribosomal protein L9 | -0.0516365 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0514381 |
| RPL11 | ribosomal protein L11 | -0.0514298 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0512421 |
| RPL21 | ribosomal protein L21 | -0.0505538 |
| RPL8 | ribosomal protein L8 | -0.0501977 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0493705 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0489767 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | -0.0480207 |
| RPS11 | ribosomal protein S11 | -0.0472441 |
| DSG3 | desmoglein 3 | -0.0459477 |
| RPLP2 | ribosomal protein, large, P2 | -0.0458931 |
| RPS14 | ribosomal protein S14 | -0.0457907 |
| RPL32 | ribosomal protein L32 | -0.0454394 |
| RPS21 | ribosomal protein S21 | -0.0453602 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.045263 |
| RPS13 | ribosomal protein S13 | -0.0436672 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0424334 |
| ITGB4 | integrin, beta 4 | -0.0414574 |
| EGR1 | early growth response 1 | -0.0412119 |
| RPS29 | ribosomal protein S29 | -0.0411076 |
| RPS5 | ribosomal protein S5 | -0.0408937 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0408869 |
| SETD5 | SET domain containing 5 | -0.0401294 |
| S100A10 | S100 calcium binding protein A10 | -0.0400138 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0397214 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0383498 |
| RPL7A | ribosomal protein L7a | -0.0383392 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0381891 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0379657 |
| PERP | PERP, TP53 apoptosis effector | -0.0376268 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0375394 |
| TXNRD1 | thioredoxin reductase 1 | -0.0372159 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0367863 |
| ASTN2 | astrotactin 2 | -0.0365841 |
| TUBA1B | tubulin, alpha 1b | -0.0364151 |
| RPL23 | ribosomal protein L23 | -0.0363332 |
| GDF15 | growth differentiation factor 15 | -0.03628 |
| KRT8 | keratin 8, type II | -0.0360036 |
| PTMA | prothymosin, alpha | -0.0355171 |
| MCU | mitochondrial calcium uniporter | -0.0350333 |
| RPL27A | ribosomal protein L27a | -0.0344529 |
| RPL15 | ribosomal protein L15 | -0.0340705 |
| FLNB | filamin B, beta | -0.0338296 |
| PCBP2 | poly(rC) binding protein 2 | -0.0336946 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0336221 |
| ANXA2 | annexin A2 | -0.0335009 |
| S100A6 | S100 calcium binding protein A6 | -0.0333679 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0331105 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0329946 |
| TMEM165 | transmembrane protein 165 | -0.0327845 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0322387 |
| ETNK1 | ethanolamine kinase 1 | -0.0319118 |
| ITGA6 | integrin, alpha 6 | -0.031862 |
| PRSS3 | protease, serine, 3 | -0.0314873 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0313996 |
| UBC | ubiquitin C | -0.0311553 |
| JMJD1C | jumonji domain containing 1C | -0.0305195 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0302619 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | -0.0300272 |
| RPL36A | ribosomal protein L36a | -0.0299017 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.029844 |
| EREG | epiregulin | -0.029562 |
| RPS19 | ribosomal protein S19 | -0.0295271 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0291581 |
| ZNF609 | zinc finger protein 609 | -0.0288719 |
| COG5 | component of oligomeric golgi complex 5 | -0.028869 |
| RBM39 | RNA binding motif protein 39 | -0.0287976 |
| FAU | Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed | -0.028497 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0279438 |
| RPL13A | ribosomal protein L13a | -0.0277108 |
| SBF2 | SET binding factor 2 | -0.0276025 |
| RPS10 | ribosomal protein S10 | -0.0274366 |
| CALU | calumenin | -0.0270069 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0269163 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0267163 |
