| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DST | dystonin | 0.222329 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.171196 |
| CAPRIN2 | caprin family member 2 | 0.147573 |
| FMNL2 | formin-like 2 | 0.129768 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.121026 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0879004 |
| MT2A | metallothionein 2A | 0.0793793 |
| TXNRD1 | thioredoxin reductase 1 | 0.0747036 |
| SPAG9 | sperm associated antigen 9 | 0.0741272 |
| RUNX1 | runt-related transcription factor 1 | 0.0711866 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0683896 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0681591 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0621551 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0614171 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0601159 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0576457 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0563023 |
| EZR | ezrin | 0.0561009 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0549265 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0521646 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0518715 |
| USP12 | ubiquitin specific peptidase 12 | 0.0472552 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.045538 |
| MT1X | metallothionein 1X | 0.044409 |
| PRELID2 | PRELI domain containing 2 | 0.0439343 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0428063 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0423542 |
| JMJD1C | jumonji domain containing 1C | 0.0410094 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0405357 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0402349 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0393401 |
| VMP1 | vacuole membrane protein 1 | 0.0387342 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0385844 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.036982 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0369492 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0364959 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0360078 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0356039 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0351354 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0341801 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0341781 |
| RTTN | rotatin | 0.0339871 |
| ANKRD36 | ankyrin repeat domain 36 | 0.033928 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0330388 |
| TMEM41B | transmembrane protein 41B | 0.0324159 |
| EREG | epiregulin | 0.032346 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0319893 |
| LDHA | lactate dehydrogenase A | 0.0317846 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0301988 |
| TSC22D1 | TSC22 domain family, member 1 | 0.030175 |
| ENO1 | enolase 1, (alpha) | 0.0299037 |
| HPCAL1 | hippocalcin-like 1 | 0.0297895 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0297352 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0296081 |
| AREG | amphiregulin | 0.029483 |
| KLF6 | Kruppel-like factor 6 | 0.029002 |
| PODXL | podocalyxin-like | 0.0286593 |
| DENND5A | DENN/MADD domain containing 5A | 0.0284994 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.028177 |
| PYGB | phosphorylase, glycogen; brain | 0.0281386 |
| RPS12 | ribosomal protein S12 | 0.0276389 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0272996 |
| PKM | pyruvate kinase, muscle | 0.0272976 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0272842 |
| MT1E | metallothionein 1E | 0.0271673 |
| SVIL | supervillin | 0.0269086 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0266358 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0262513 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0261151 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.0258162 |
| CALR | calreticulin | 0.025772 |
| SMYD3 | SET and MYND domain containing 3 | 0.02558 |
| SQSTM1 | sequestosome 1 | 0.025571 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0255033 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0246515 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0244639 |
| CMIP | c-Maf inducing protein | 0.0243925 |
| HOMER1 | homer scaffolding protein 1 | 0.0242221 |
| TOP1 | topoisomerase (DNA) I | 0.024196 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0238361 |
| VEGFC | vascular endothelial growth factor C | 0.0237622 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0233746 |
| ACTN1 | actinin, alpha 1 | 0.023355 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.0227358 |
| VCL | vinculin | 0.0226016 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0224828 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0224394 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0224216 |
| CALB2 | calbindin 2 | 0.0223617 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0223116 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0221982 |
| PLEC | plectin | 0.0221186 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0220967 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.0217635 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0215121 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0215045 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0213493 |
| PLK2 | polo-like kinase 2 | 0.0213126 |
| MB21D2 | Mab-21 domain containing 2 | 0.0211616 |
| USP34 | ubiquitin specific peptidase 34 | 0.0210507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.150916 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.141075 |
| PTMA | prothymosin, alpha | -0.125571 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0873796 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0769851 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0713442 |
| HLA-B | major histocompatibility complex, class I, B | -0.0640956 |
| EHBP1 | EH domain binding protein 1 | -0.059928 |
| TNS3 | tensin 3 | -0.058536 |
| TMSB10 | thymosin beta 10 | -0.0575277 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0563688 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.056083 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0524747 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0491415 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0475402 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.045665 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0438171 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0437151 |
| RPL35A | ribosomal protein L35a | -0.0425609 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0399639 |
| FTL | ferritin, light polypeptide | -0.0384992 |
| CADM2 | cell adhesion molecule 2 | -0.0380664 |
| RIGI | RNA sensor RIG-I | -0.0378653 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0353582 |
| SRGN | serglycin | -0.035196 |
| EFNA5 | ephrin-A5 | -0.0349369 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0344346 |
| EGR1 | early growth response 1 | -0.0339748 |
| RPS19 | ribosomal protein S19 | -0.0336638 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0336411 |
| RPS6 | ribosomal protein S6 | -0.0335079 |
| TP63 | tumor protein p63 | -0.0333992 |
| PTK2 | protein tyrosine kinase 2 | -0.0331725 |
| HMGA1 | high mobility group AT-hook 1 | -0.0324883 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0323719 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0322319 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0321078 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0313452 |
| TMEM123 | transmembrane protein 123 | -0.0309224 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0307722 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0304329 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.029387 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.029016 |
| GNAS | GNAS complex locus | -0.0278786 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -0.026799 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0264717 |
| ACTG1 | actin gamma 1 | -0.0262023 |
| RPL36A | ribosomal protein L36a | -0.0243791 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0242083 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0241104 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0240541 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0238508 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0236139 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0234723 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0231567 |
| EXOC4 | exocyst complex component 4 | -0.0229419 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0229024 |
| AHNAK | AHNAK nucleoprotein | -0.0228631 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0228297 |
| RPS8 | ribosomal protein S8 | -0.0227318 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0223943 |
| HLA-E | major histocompatibility complex, class I, E | -0.0222579 |
| RPS15 | ribosomal protein S15 | -0.0220035 |
| EPHA4 | EPH receptor A4 | -0.0219673 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0219037 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0216019 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0215458 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0214553 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0213317 |
| GLG1 | golgi glycoprotein 1 | -0.0212791 |
| EGFR | epidermal growth factor receptor | -0.0211528 |
| HDAC9 | histone deacetylase 9 | -0.0210586 |
| B2M | beta-2-microglobulin | -0.0208311 |
| ZNF609 | zinc finger protein 609 | -0.0207364 |
| TP53 | tumor protein p53 | -0.020663 |
| XAF1 | XIAP associated factor 1 | -0.0206483 |
| RPS23 | ribosomal protein S23 | -0.0206481 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0204978 |
| PRRC2B | proline-rich coiled-coil 2B | -0.02047 |
| PMP22 | peripheral myelin protein 22 | -0.0203107 |
| RPS24 | ribosomal protein S24 | -0.0201622 |
| RPS29 | ribosomal protein S29 | -0.0201001 |
| DPH6 | diphthamine biosynthesis 6 | -0.0198235 |
| RPL31 | ribosomal protein L31 | -0.019682 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0195833 |
| PGK1 | phosphoglycerate kinase 1 | -0.0191828 |
| RPS10 | ribosomal protein S10 | -0.0190452 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0187264 |
| MYADM | myeloid-associated differentiation marker | -0.0184107 |
| PATJ | PATJ crumbs cell polarity complex component | -0.01817 |
| RPS16 | ribosomal protein S16 | -0.0180533 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0180131 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | -0.0180078 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0178428 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0177977 |
| S100A9 | S100 calcium binding protein A9 | -0.0176969 |
| PLIN2 | perilipin 2 | -0.0176625 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0174715 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0174423 |
| BSG | basigin (Ok blood group) | -0.0174323 |
