| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLTM | SAFB-like, transcription modulator | 0.117275 |
| GRAMD1B | GRAM domain containing 1B | 0.102348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0886411 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0704905 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0674821 |
| MCL1 | myeloid cell leukemia 1 | 0.0636033 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.06058 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0598476 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0561521 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0559263 |
| SPAG9 | sperm associated antigen 9 | 0.0545076 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0525897 |
| MT2A | metallothionein 2A | 0.0477109 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0474687 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0467295 |
| TOP1 | topoisomerase (DNA) I | 0.0453932 |
| INTS6 | integrator complex subunit 6 | 0.0451541 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0442736 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0429978 |
| ENO1 | enolase 1, (alpha) | 0.0421206 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0404584 |
| HOMER1 | homer scaffolding protein 1 | 0.0397443 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0389858 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0380312 |
| MAP7 | microtubule-associated protein 7 | 0.0374429 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0368661 |
| BMP6 | bone morphogenetic protein 6 | 0.0366155 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0362662 |
| RUNX1 | runt-related transcription factor 1 | 0.0351907 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0348224 |
| RPS3 | ribosomal protein S3 | 0.0339872 |
| VMP1 | vacuole membrane protein 1 | 0.0339627 |
| NABP1 | nucleic acid binding protein 1 | 0.0338118 |
| LAMA4 | laminin, alpha 4 | 0.0333352 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0325985 |
| HSPA8 | heat shock 70kDa protein 8 | 0.032423 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.031558 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0295653 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0295568 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0288723 |
| AREG | amphiregulin | 0.0280147 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.027864 |
| SIK3 | SIK family kinase 3 | 0.027737 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0277211 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.027512 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0274192 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0271571 |
| DTNA | dystrobrevin, alpha | 0.0266325 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0262583 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0259194 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0255897 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0254916 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0254719 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0253198 |
| PKM | pyruvate kinase, muscle | 0.0251453 |
| CES1 | carboxylesterase 1 | 0.0250738 |
| JMJD1C | jumonji domain containing 1C | 0.0249651 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0244422 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0241034 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0237898 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0237066 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0234706 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0233257 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0226452 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0223233 |
| GPATCH2L | G patch domain containing 2-like | 0.0220321 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | 0.0218986 |
| KYNU | kynureninase | 0.0218754 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0216852 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0214945 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0212019 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0211061 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0210071 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0209511 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0205121 |
| SMYD3 | SET and MYND domain containing 3 | 0.0203565 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0203141 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0199671 |
| KIAA1217 | KIAA1217 | 0.0199214 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0198089 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0195977 |
| PYGL | phosphorylase, glycogen, liver | 0.0193942 |
| HYOU1 | hypoxia up-regulated 1 | 0.019254 |
| RPL41 | ribosomal protein L41 | 0.0192098 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0191535 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0191409 |
| SMAD3 | SMAD family member 3 | 0.0190921 |
| LRP12 | low density lipoprotein receptor-related protein 12 | 0.0189598 |
| PRELID2 | PRELI domain containing 2 | 0.0186796 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | 0.0185973 |
| RPL4 | ribosomal protein L4 | 0.0184954 |
| RNF213 | ring finger protein 213 | 0.0184454 |
| VCL | vinculin | 0.0181571 |
| RPS12 | ribosomal protein S12 | 0.0181551 |
| RAD51B | RAD51 paralog B | 0.0181291 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0180564 |
| MYO1E | myosin IE | 0.0180423 |
| DST | dystonin | 0.018034 |
| WWOX | WW domain containing oxidoreductase | 0.018018 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.017892 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.18413 |
| EGFR | epidermal growth factor receptor | -0.134926 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114916 |
| NDRG1 | N-myc downstream regulated 1 | -0.100164 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0982543 |
| TMSB10 | thymosin beta 10 | -0.0916159 |
| ACTG1 | actin gamma 1 | -0.0819037 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.079322 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0675209 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0646696 |
| S100A10 | S100 calcium binding protein A10 | -0.0603544 |
| ASPH | aspartate beta-hydroxylase | -0.0568623 |
| KRT7 | keratin 7, type II | -0.0492798 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0457592 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0446723 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0446608 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0427927 |
| CCND1 | cyclin D1 | -0.0414908 |
| TXNRD1 | thioredoxin reductase 1 | -0.0377798 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0374178 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0368268 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0366492 |
| KRT18 | keratin 18, type I | -0.0362122 |
| AHNAK | AHNAK nucleoprotein | -0.0358425 |
| ANXA2 | annexin A2 | -0.0355513 |
| LAMC2 | laminin, gamma 2 | -0.0341006 |
| EGR1 | early growth response 1 | -0.0337022 |
| TMEM165 | transmembrane protein 165 | -0.0336419 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0335906 |
| CST3 | cystatin C | -0.0333146 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0333043 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0330739 |
| CAV2 | caveolin 2 | -0.0326971 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0314962 |
| PARD3 | par-3 family cell polarity regulator | -0.0309937 |
| TNS3 | tensin 3 | -0.0305425 |
| RIN2 | Ras and Rab interactor 2 | -0.0299727 |
| PTMA | prothymosin, alpha | -0.0292163 |
| HDLBP | high density lipoprotein binding protein | -0.0290715 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0288992 |
| S100A6 | S100 calcium binding protein A6 | -0.0286287 |
| WASF2 | WAS protein family, member 2 | -0.0278786 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0268427 |
| HLA-B | major histocompatibility complex, class I, B | -0.0265132 |
| SCEL | sciellin | -0.0259237 |
| LMO7 | LIM domain 7 | -0.0255748 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0255582 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0248598 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0243693 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0243506 |
| MGAT4C | MGAT4 family, member C | -0.0241626 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0241403 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0236486 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0232499 |
| TPM4 | tropomyosin 4 | -0.0231386 |
| GNAS | GNAS complex locus | -0.0231186 |
| TRIM56 | tripartite motif containing 56 | -0.0231028 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0229042 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0227718 |
| KRT8 | keratin 8, type II | -0.0225825 |
| PERP | PERP, TP53 apoptosis effector | -0.0223603 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0222363 |
| FLNB | filamin B, beta | -0.0219535 |
| KRT19 | keratin 19, type I | -0.0216128 |
| DSG2 | desmoglein 2 | -0.021576 |
| HMGA1 | high mobility group AT-hook 1 | -0.0213273 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0210359 |
| SBF2 | SET binding factor 2 | -0.0207739 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.020522 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0199907 |
| AGR2 | anterior gradient 2 | -0.0199753 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0198211 |
| HM13 | histocompatibility (minor) 13 | -0.0196785 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0189801 |
| SLMAP | sarcolemma associated protein | -0.0189714 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0187848 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0187473 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.018615 |
| CUX1 | cut-like homeobox 1 | -0.0185249 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0183201 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0182873 |
| RIOK3 | RIO kinase 3 | -0.0181151 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0179782 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0178704 |
| TPD52 | tumor protein D52 | -0.0177386 |
| CP | ceruloplasmin (ferroxidase) | -0.017634 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0175688 |
| BMP7 | bone morphogenetic protein 7 | -0.0173231 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0172609 |
| TAOK3 | TAO kinase 3 | -0.0172576 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0171607 |
| CD99 | CD99 molecule | -0.0171231 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.017 |
| ADGRF1 | adhesion G protein-coupled receptor F1 | -0.0168985 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0168183 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0167255 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.016721 |
| LDHA | lactate dehydrogenase A | -0.0163494 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0161112 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0156874 |
