| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.158357 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.113105 |
| ENO1 | enolase 1, (alpha) | 0.0973022 |
| SMAD3 | SMAD family member 3 | 0.0954738 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0898234 |
| ASPH | aspartate beta-hydroxylase | 0.0799865 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0756117 |
| FN1 | fibronectin 1 | 0.0741434 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0731779 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.071979 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0685629 |
| PKM | pyruvate kinase, muscle | 0.0674189 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0672297 |
| LOX | lysyl oxidase | 0.0669822 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0669547 |
| PRELID2 | PRELI domain containing 2 | 0.0665912 |
| NAV2 | neuron navigator 2 | 0.0634079 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0622209 |
| DST | dystonin | 0.0621717 |
| ANGPTL4 | angiopoietin-like 4 | 0.0619679 |
| MT2A | metallothionein 2A | 0.0562863 |
| HMGA2 | high mobility group AT-hook 2 | 0.0557054 |
| LDHA | lactate dehydrogenase A | 0.0556775 |
| LOXL2 | lysyl oxidase-like 2 | 0.0554297 |
| IFI44L | interferon-induced protein 44-like | 0.0544543 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0534382 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0530019 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0526815 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0519658 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0518306 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.051524 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0513075 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0492262 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0489075 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0485292 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0482172 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0468383 |
| SEPTIN9 | septin 9 | 0.0465167 |
| CD44 | CD44 molecule (Indian blood group) | 0.0464755 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.046182 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0456408 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0444382 |
| ADD3 | adducin 3 (gamma) | 0.0442634 |
| FAM13A | family with sequence similarity 13, member A | 0.0442126 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0437408 |
| FAM20C | family with sequence similarity 20, member C | 0.043619 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0433855 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.0426676 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.042429 |
| CALR | calreticulin | 0.0421568 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0419917 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0407906 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0405969 |
| SQSTM1 | sequestosome 1 | 0.0391832 |
| NTN4 | netrin 4 | 0.0389604 |
| MYO10 | myosin X | 0.0387981 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0379294 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0379236 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0378481 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0372518 |
| APP | amyloid beta (A4) precursor protein | 0.0364374 |
| WLS | wntless Wnt ligand secretion mediator | 0.036212 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0358364 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0356068 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0350387 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0349843 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0348699 |
| EZR | ezrin | 0.034415 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0339516 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0335925 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0321015 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0320956 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0320371 |
| ADM | adrenomedullin | 0.0320065 |
| HAS2 | hyaluronan synthase 2 | 0.0314001 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.030987 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0309397 |
| ZNF638 | zinc finger protein 638 | 0.0309345 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0306567 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0305734 |
| FTL | ferritin, light polypeptide | 0.0305425 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0301649 |
| ATXN1 | ataxin 1 | 0.0300054 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.029998 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.029917 |
| RNF213 | ring finger protein 213 | 0.0297166 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0296927 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.0293717 |
| INTS6 | integrator complex subunit 6 | 0.0292018 |
| TMSB4X | thymosin beta 4, X-linked | 0.0286727 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0285557 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0285049 |
| RPS3 | ribosomal protein S3 | 0.0278559 |
| NGLY1 | N-glycanase 1 | 0.0276114 |
| SFTPA2 | surfactant protein A2 | 0.0275061 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.02749 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.027152 |
| RPL4 | ribosomal protein L4 | 0.0271243 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0268258 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0267108 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.15787 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0857041 |
| OSMR | oncostatin M receptor | -0.084479 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0771354 |
| GOLGA4 | golgin A4 | -0.0737222 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0727572 |
| USP34 | ubiquitin specific peptidase 34 | -0.0703325 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0694039 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0655017 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0634785 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0574186 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0565922 |
| EGR1 | early growth response 1 | -0.0562612 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0560848 |
| TMEM165 | transmembrane protein 165 | -0.0540808 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0538543 |
| VRK2 | vaccinia related kinase 2 | -0.0514654 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0512469 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0484922 |
| RBM39 | RNA binding motif protein 39 | -0.0483766 |
| TMSB10 | thymosin beta 10 | -0.0480987 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0470942 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.046485 |
| NRG1 | neuregulin 1 | -0.0457069 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0421782 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0417891 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0394245 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0390759 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.0388511 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0388335 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0387842 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.038367 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0378765 |
| ATG7 | autophagy related 7 | -0.0371411 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0371276 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0365363 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0358529 |
| DENND4A | DENN/MADD domain containing 4A | -0.0357803 |
| FRMD4A | FERM domain containing 4A | -0.03573 |
| DNER | delta/notch-like EGF repeat containing | -0.0356988 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0356833 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0356685 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | -0.0356457 |
| ZNF609 | zinc finger protein 609 | -0.0353091 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0350417 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0346391 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0342975 |
| SETD5 | SET domain containing 5 | -0.0338828 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0330185 |
| CDH13 | cadherin 13 | -0.032898 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0325111 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0323161 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0322176 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0316376 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0311249 |
| NF1 | neurofibromin 1 | -0.0308701 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0307699 |
| RAB5A | RAB5A, member RAS oncogene family | -0.030404 |
| CALU | calumenin | -0.0299583 |
| SBF2 | SET binding factor 2 | -0.0298592 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0296692 |
| COPA | coatomer protein complex, subunit alpha | -0.0291176 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0291014 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0290695 |
| ETV6 | ets variant 6 | -0.0287187 |
| STC1 | stanniocalcin 1 | -0.0287091 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0278823 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.027633 |
| SRP54 | signal recognition particle 54kDa | -0.0276307 |
| FNBP1 | formin binding protein 1 | -0.0275666 |
| COG5 | component of oligomeric golgi complex 5 | -0.0275306 |
| NAV3 | neuron navigator 3 | -0.0275288 |
| CFDP1 | craniofacial development protein 1 | -0.0274966 |
| NUMB | numb homolog (Drosophila) | -0.0273654 |
| GPC6 | glypican 6 | -0.0273061 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0269915 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0269801 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0269202 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0268848 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0266813 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.026666 |
| SEC24D | SEC24 family member D | -0.0265968 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0265267 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0263475 |
| MORF4L2 | mortality factor 4 like 2 | -0.0263422 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0260372 |
| ZFP91 | ZFP91 zinc finger protein | -0.0259977 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0259784 |
| ARF4 | ADP-ribosylation factor 4 | -0.0257651 |
| HM13 | histocompatibility (minor) 13 | -0.0257304 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0255328 |
| PCNX1 | pecanex 1 | -0.0250991 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0249934 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0248149 |
| ADAM28 | ADAM metallopeptidase domain 28 | -0.0247494 |
| PCNX4 | pecanex 4 | -0.0244179 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) | -0.0241698 |
| HDLBP | high density lipoprotein binding protein | -0.0241446 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.024041 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0240363 |
