| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.13865 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.125765 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.121966 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.110258 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0959383 |
| FMNL2 | formin-like 2 | 0.0851936 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0844955 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0793581 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0768162 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0761245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0751551 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0742125 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0695182 |
| FAM107B | family with sequence similarity 107, member B | 0.0639042 |
| APP | amyloid beta (A4) precursor protein | 0.0632961 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0631751 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0627408 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0602902 |
| DST | dystonin | 0.0597673 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0587014 |
| CALR | calreticulin | 0.0572391 |
| PKM | pyruvate kinase, muscle | 0.0565428 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0557181 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0545224 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0525126 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0512336 |
| WWOX | WW domain containing oxidoreductase | 0.0505452 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0498477 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0492807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0492394 |
| MYOF | myoferlin | 0.0492311 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.049229 |
| ASPH | aspartate beta-hydroxylase | 0.0481283 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0476239 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0473873 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0459822 |
| TPM3 | tropomyosin 3 | 0.0459074 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0452526 |
| ENO1 | enolase 1, (alpha) | 0.0450378 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0450029 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0437004 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0431095 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0429622 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0429359 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0427948 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0426065 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0425301 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0423863 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422174 |
| CMIP | c-Maf inducing protein | 0.0420117 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0420055 |
| FLNB | filamin B, beta | 0.0419379 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0418696 |
| FUS | FUS RNA binding protein | 0.0405326 |
| ACTN1 | actinin, alpha 1 | 0.0405076 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0399791 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0396615 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0382042 |
| RBM39 | RNA binding motif protein 39 | 0.0375378 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.037355 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0362245 |
| SMAD3 | SMAD family member 3 | 0.0352892 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0348458 |
| RPL23 | ribosomal protein L23 | 0.0347648 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0341725 |
| CANX | calnexin | 0.0339142 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0338557 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0335304 |
| CTBP2 | C-terminal binding protein 2 | 0.0334831 |
| NCKAP1 | NCK-associated protein 1 | 0.0332623 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0331645 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0331223 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0330518 |
| FTL | ferritin, light polypeptide | 0.0329376 |
| CUL3 | cullin 3 | 0.0324304 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0324303 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0322536 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0322516 |
| EZR | ezrin | 0.0317943 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0315521 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0309046 |
| RPL41 | ribosomal protein L41 | 0.0304787 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0302461 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0296219 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0296044 |
| GOLGA4 | golgin A4 | 0.0294847 |
| PRELID2 | PRELI domain containing 2 | 0.0293366 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0292928 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0291544 |
| UTRN | utrophin | 0.0291493 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0291194 |
| COPA | coatomer protein complex, subunit alpha | 0.0290191 |
| USP36 | ubiquitin specific peptidase 36 | 0.028469 |
| NDRG1 | N-myc downstream regulated 1 | 0.0277687 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0277678 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0276219 |
| PARD3 | par-3 family cell polarity regulator | 0.0275045 |
| MCL1 | myeloid cell leukemia 1 | 0.0272003 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0270862 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0269928 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.312877 |
| IGF2 | insulin-like growth factor 2 | -0.0974383 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0891538 |
| EGR1 | early growth response 1 | -0.0744635 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.06452 |
| TXNRD1 | thioredoxin reductase 1 | -0.0619525 |
| OSMR | oncostatin M receptor | -0.0581388 |
| VIM | vimentin | -0.0527535 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0370464 |
| TMSB10 | thymosin beta 10 | -0.0350895 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0348691 |
| HDAC9 | histone deacetylase 9 | -0.0344729 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0336909 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0306268 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.02932 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0290597 |
| S100A6 | S100 calcium binding protein A6 | -0.0280385 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0276427 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0275454 |
| RTN4 | reticulon 4 | -0.0247511 |
| S100A10 | S100 calcium binding protein A10 | -0.0237162 |
| AK1 | adenylate kinase 1 | -0.0237124 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0234235 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0233009 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.023092 |
| GRAMD1B | GRAM domain containing 1B | -0.0226641 |
| PFN1 | profilin 1 | -0.0225186 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0219544 |
| RPS25 | ribosomal protein S25 | -0.0216147 |
| IL6 | interleukin 6 | -0.0212667 |
| NNMT | nicotinamide N-methyltransferase | -0.0210266 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0202171 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.020119 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0193251 |
| RHOA | ras homolog family member A | -0.0188888 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0177673 |
| NTN4 | netrin 4 | -0.0177097 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0169925 |
| ASTN2 | astrotactin 2 | -0.0167919 |
| DENND4A | DENN/MADD domain containing 4A | -0.0166591 |
| MFF | mitochondrial fission factor | -0.0163654 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0163549 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0162347 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0162068 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0160824 |
| MYADM | myeloid-associated differentiation marker | -0.0157476 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.015686 |
| PCNX4 | pecanex 4 | -0.0154329 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0154143 |
| CENPE | centromere protein E, 312kDa | -0.015269 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.015258 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0151034 |
| HDGF | hepatoma-derived growth factor | -0.0150726 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | -0.0150686 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | -0.0150367 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0148561 |
| ACTG1 | actin gamma 1 | -0.0146539 |
| HMGA1 | high mobility group AT-hook 1 | -0.0146033 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0145701 |
| RIN2 | Ras and Rab interactor 2 | -0.0145579 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0142359 |
| RPS15 | ribosomal protein S15 | -0.0141306 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0140764 |
| LRP10 | low density lipoprotein receptor-related protein 10 | -0.0139524 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0139155 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0139145 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0138703 |
| ERBIN | erbb2 interacting protein | -0.0138533 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0138288 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0137769 |
| RPS23 | ribosomal protein S23 | -0.0137299 |
| NAV3 | neuron navigator 3 | -0.0136852 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0136692 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0136656 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0136643 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0134806 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0133934 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0131225 |
| RAB10 | RAB10, member RAS oncogene family | -0.0128982 |
| MKI67 | marker of proliferation Ki-67 | -0.0128895 |
| NUP58 | nucleoporin 58 | -0.0128859 |
| RPS10 | ribosomal protein S10 | -0.0127268 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0124119 |
| BMP5 | bone morphogenetic protein 5 | -0.0123651 |
| TNFAIP8 | tumor necrosis factor, alpha-induced protein 8 | -0.0122476 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0122102 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0122047 |
| POTEF | POTE ankyrin domain family, member F | -0.0121413 |
| GLIS3 | GLIS family zinc finger 3 | -0.0121216 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.012086 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0120657 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0120422 |
| RPL39 | ribosomal protein L39 | -0.0119412 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0118922 |
| MAP1B | microtubule-associated protein 1B | -0.0117541 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0115307 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0113317 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0113302 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0112927 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0112326 |
