| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | 0.229819 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.159754 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.151008 |
| EGFR | epidermal growth factor receptor | 0.131028 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.107426 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0932518 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0858015 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0758636 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0751444 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0750752 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0726675 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0715366 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0708946 |
| EFNA5 | ephrin-A5 | 0.0695756 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0693691 |
| HMGA2 | high mobility group AT-hook 2 | 0.0654284 |
| MYO1E | myosin IE | 0.0653189 |
| NDRG1 | N-myc downstream regulated 1 | 0.064277 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0571448 |
| LAMC2 | laminin, gamma 2 | 0.057031 |
| FMN1 | formin 1 | 0.0564436 |
| DSPP | dentin sialophosphoprotein | 0.0560694 |
| ATOSA | atos homolog A | 0.0558821 |
| TJP1 | tight junction protein 1 | 0.0554838 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0552838 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0551144 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0545936 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0522092 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0513504 |
| OGA | O-GlcNAcase | 0.0504514 |
| SLTM | SAFB-like, transcription modulator | 0.0482998 |
| CD44 | CD44 molecule (Indian blood group) | 0.0479327 |
| FRYL | FRY-like | 0.046589 |
| MYO5B | myosin VB | 0.0464365 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0459477 |
| TXNRD1 | thioredoxin reductase 1 | 0.0446499 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0442913 |
| VEGFA | vascular endothelial growth factor A | 0.0439092 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0435386 |
| NABP1 | nucleic acid binding protein 1 | 0.0428565 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0427161 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0426775 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | 0.0420152 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0418274 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0413751 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0412042 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0404507 |
| AHNAK | AHNAK nucleoprotein | 0.0402277 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0401909 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0400078 |
| SVIL | supervillin | 0.0399826 |
| PCBP2 | poly(rC) binding protein 2 | 0.0395386 |
| DSG2 | desmoglein 2 | 0.0392972 |
| FAM13A | family with sequence similarity 13, member A | 0.039034 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0389367 |
| NEBL | nebulette | 0.0388339 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0385831 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0384361 |
| CTBP2 | C-terminal binding protein 2 | 0.037516 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0374168 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0373543 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0368609 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0367724 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0365848 |
| IGF2 | insulin-like growth factor 2 | 0.0361251 |
| LDHA | lactate dehydrogenase A | 0.0353759 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0353236 |
| LMO7 | LIM domain 7 | 0.0347383 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0346855 |
| GLCCI1 | glucocorticoid induced 1 | 0.0343135 |
| PRELID2 | PRELI domain containing 2 | 0.0342939 |
| USP53 | ubiquitin specific peptidase 53 | 0.0336138 |
| EHBP1 | EH domain binding protein 1 | 0.0336075 |
| TXNIP | thioredoxin interacting protein | 0.0334266 |
| CANX | calnexin | 0.0329806 |
| LAMA4 | laminin, alpha 4 | 0.0328882 |
| INHBA | inhibin, beta A | 0.0326707 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0322047 |
| ATP13A3 | ATPase type 13A3 | 0.0321241 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.032002 |
| COL1A2 | collagen, type I, alpha 2 | 0.0319058 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0318917 |
| OFD1 | oral-facial-digital syndrome 1 | 0.0318308 |
| VGLL3 | vestigial-like family member 3 | 0.0317179 |
| BBX | bobby sox homolog (Drosophila) | 0.0315843 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0315611 |
| HLA-B | major histocompatibility complex, class I, B | 0.0314716 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0313677 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0313027 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0310686 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0309588 |
| SLK | STE20-like kinase | 0.0308259 |
| FNBP1L | formin binding protein 1-like | 0.0306351 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0305807 |
| KYNU | kynureninase | 0.03012 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0300083 |
| NPTN | neuroplastin | 0.029983 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0298668 |
| CMIP | c-Maf inducing protein | 0.0298502 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0297519 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.178606 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0734116 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0641432 |
| FN1 | fibronectin 1 | -0.0573544 |
| RORA | RAR-related orphan receptor A | -0.057056 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0528731 |
| S100A10 | S100 calcium binding protein A10 | -0.0528203 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0498127 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0497275 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0488213 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0457025 |
| NRG1 | neuregulin 1 | -0.0455525 |
| LMNA | lamin A/C | -0.0444984 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0443192 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0440707 |
| FTL | ferritin, light polypeptide | -0.0440501 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0439214 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0437718 |
| ARF1 | ADP-ribosylation factor 1 | -0.0436867 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0436816 |
| PDE10A | phosphodiesterase 10A | -0.0431006 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0429983 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0414552 |
| DIDO1 | death inducer-obliterator 1 | -0.0411544 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0409222 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0402507 |
| GOLGB1 | golgin B1 | -0.0402396 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.039404 |
| RPS23 | ribosomal protein S23 | -0.0393547 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0390371 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | -0.0388312 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0384344 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0381416 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0375722 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0372806 |
| FRMD5 | FERM domain containing 5 | -0.037149 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0368137 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0367155 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.03671 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0365743 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0363593 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0361993 |
| CCDC47 | coiled-coil domain containing 47 | -0.0359391 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0358231 |
| LTN1 | listerin E3 ubiquitin protein ligase 1 | -0.0357931 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0356174 |
| DENND1A | DENN/MADD domain containing 1A | -0.0353507 |
| MATR3 | matrin 3 | -0.0353178 |
| CDH13 | cadherin 13 | -0.0345962 |
| PAPOLA | poly(A) polymerase alpha | -0.0345545 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0343675 |
| ZNF207 | zinc finger protein 207 | -0.0339897 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0339851 |
| COPA | coatomer protein complex, subunit alpha | -0.0339605 |
| VMP1 | vacuole membrane protein 1 | -0.0334029 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.033213 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0329243 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.032764 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0327105 |
| DENND4A | DENN/MADD domain containing 4A | -0.0324709 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0323568 |
| MAP1B | microtubule-associated protein 1B | -0.0321512 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0319243 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0319107 |
| ZNF609 | zinc finger protein 609 | -0.0316538 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0316529 |
| GNL2 | guanine nucleotide binding protein-like 2 (nucleolar) | -0.0315665 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0313865 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0311304 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0310844 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0308741 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0308175 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0308031 |
| KDM1A | lysine (K)-specific demethylase 1A | -0.0306493 |
| TEX10 | testis expressed 10 | -0.0305992 |
| RYK | receptor-like tyrosine kinase | -0.030457 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0302589 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0302257 |
| SETD5 | SET domain containing 5 | -0.0301343 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0300462 |
| RNF130 | ring finger protein 130 | -0.0299617 |
| EZR | ezrin | -0.0298231 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0296281 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0295819 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0295451 |
| NF1 | neurofibromin 1 | -0.0295251 |
| UBE3A | ubiquitin protein ligase E3A | -0.0294834 |
| THBS1 | thrombospondin 1 | -0.0293879 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0293193 |
| GNAS | GNAS complex locus | -0.0282179 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0281793 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0279893 |
| AHR | aryl hydrocarbon receptor | -0.0278944 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | -0.0278835 |
| STK17A | serine/threonine kinase 17a | -0.0277113 |
| CERS6 | ceramide synthase 6 | -0.0276501 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.027564 |
| HDAC9 | histone deacetylase 9 | -0.0275556 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0275532 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0272958 |
