| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.227554 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.131313 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.11063 |
| LAMC2 | laminin, gamma 2 | 0.0937996 |
| AHNAK | AHNAK nucleoprotein | 0.08736 |
| DSPP | dentin sialophosphoprotein | 0.0871044 |
| PLEC | plectin | 0.0846849 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0806568 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0675548 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0666917 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0659401 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0657578 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0652204 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0626136 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0606755 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0599861 |
| LAMB3 | laminin, beta 3 | 0.0585809 |
| UPP1 | uridine phosphorylase 1 | 0.0575703 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0564247 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0554306 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0553494 |
| ASPH | aspartate beta-hydroxylase | 0.0539467 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0524464 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0509899 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0500585 |
| SDC4 | syndecan 4 | 0.0493285 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0483975 |
| SGMS2 | sphingomyelin synthase 2 | 0.0449282 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0444523 |
| KIAA1217 | KIAA1217 | 0.0440493 |
| SMAD3 | SMAD family member 3 | 0.0433778 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0408926 |
| CD44 | CD44 molecule (Indian blood group) | 0.0404542 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0398298 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0391894 |
| FHIT | fragile histidine triad | 0.0388329 |
| NAV2 | neuron navigator 2 | 0.0382894 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.038034 |
| SEPTIN9 | septin 9 | 0.0376614 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0371254 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0370088 |
| ENO1 | enolase 1, (alpha) | 0.0368914 |
| GRAMD2B | GRAM domain containing 2B | 0.0358672 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0350705 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0348763 |
| DST | dystonin | 0.0346956 |
| EGFR | epidermal growth factor receptor | 0.0345678 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0345403 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0341947 |
| SEPTIN11 | septin 11 | 0.0341682 |
| TJP2 | tight junction protein 2 | 0.0338424 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0337083 |
| DUSP10 | dual specificity phosphatase 10 | 0.0336109 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0334711 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.033409 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0332129 |
| RUNX1 | runt-related transcription factor 1 | 0.0331937 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0331155 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0329864 |
| VGLL3 | vestigial-like family member 3 | 0.0328976 |
| CALR | calreticulin | 0.0326054 |
| TXNRD1 | thioredoxin reductase 1 | 0.0317703 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0312501 |
| RNF213 | ring finger protein 213 | 0.0312178 |
| SQSTM1 | sequestosome 1 | 0.030822 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0308169 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0300784 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0299808 |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 | 0.0297134 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0296655 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0293234 |
| DSG2 | desmoglein 2 | 0.028834 |
| NTN4 | netrin 4 | 0.0287169 |
| EZR | ezrin | 0.0286454 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.028523 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0284563 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0284518 |
| MYO5B | myosin VB | 0.0282818 |
| IRF6 | interferon regulatory factor 6 | 0.0280375 |
| LMO7 | LIM domain 7 | 0.027513 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0272079 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.02717 |
| MAP1B | microtubule-associated protein 1B | 0.0270508 |
| RIGI | RNA sensor RIG-I | 0.0270293 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0269615 |
| TJP1 | tight junction protein 1 | 0.0268309 |
| SMYD3 | SET and MYND domain containing 3 | 0.026815 |
| JAK1 | Janus kinase 1 | 0.0266705 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0265997 |
| ANXA1 | annexin A1 | 0.0263257 |
| INTS6 | integrator complex subunit 6 | 0.0262961 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides | 0.0261347 |
| G0S2 | G0/G1 switch 2 | 0.025982 |
| MX1 | MX dynamin-like GTPase 1 | 0.025759 |
| RASAL2 | RAS protein activator like 2 | 0.0254266 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0253586 |
| ATXN1 | ataxin 1 | 0.025317 |
| ANO6 | anoctamin 6 | 0.0250706 |
| STEAP4 | STEAP family member 4 | 0.0241965 |
| CCNG2 | cyclin G2 | 0.0239323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | -0.159515 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0810379 |
| GOLGA4 | golgin A4 | -0.0794597 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0752319 |
| ACTG1 | actin gamma 1 | -0.0751275 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0713051 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0701252 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0699839 |
| FN1 | fibronectin 1 | -0.069582 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0694306 |
| PTMA | prothymosin, alpha | -0.0666464 |
| NDRG1 | N-myc downstream regulated 1 | -0.0631906 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0576406 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0548826 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0539829 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0526182 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0524655 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0511021 |
| WASF2 | WAS protein family, member 2 | -0.0510277 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0509738 |
| TMEM165 | transmembrane protein 165 | -0.0489494 |
| FTL | ferritin, light polypeptide | -0.0481166 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0478904 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0452188 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0447647 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0425169 |
| CERT1 | ceramide transporter 1 | -0.0400473 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0396867 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0392454 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0381288 |
| TFG | TRK-fused gene | -0.0368549 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0362122 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0360704 |
| TMF1 | TATA element modulatory factor 1 | -0.0359925 |
| TPM4 | tropomyosin 4 | -0.0359574 |
| CD109 | CD109 molecule | -0.0353478 |
| FNIP1 | folliculin interacting protein 1 | -0.0344802 |
| TMSB10 | thymosin beta 10 | -0.0343261 |
| RBM25 | RNA binding motif protein 25 | -0.0343155 |
| SPAG9 | sperm associated antigen 9 | -0.0342046 |
| VCL | vinculin | -0.0341641 |
| SLMAP | sarcolemma associated protein | -0.0334426 |
| RCOR1 | REST corepressor 1 | -0.032953 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0324103 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0322432 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0320625 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0320164 |
| COPA | coatomer protein complex, subunit alpha | -0.0318476 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0318231 |
| MSI2 | musashi RNA-binding protein 2 | -0.0316073 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.03135 |
| ZNF207 | zinc finger protein 207 | -0.0311531 |
| SRP54 | signal recognition particle 54kDa | -0.0310892 |
| CCND1 | cyclin D1 | -0.0310185 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0307977 |
| KLHL24 | kelch-like family member 24 | -0.030273 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0301731 |
| PGK1 | phosphoglycerate kinase 1 | -0.0301704 |
| GNAS | GNAS complex locus | -0.0301677 |
| ARF4 | ADP-ribosylation factor 4 | -0.0296493 |
| NF1 | neurofibromin 1 | -0.0294812 |
| ATOSA | atos homolog A | -0.0293474 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0288086 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0287837 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0287325 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0281705 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0274213 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.026888 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0267804 |
| RAI14 | retinoic acid induced 14 | -0.026728 |
| GRB10 | growth factor receptor-bound protein 10 | -0.026711 |
| CCNL1 | cyclin L1 | -0.0264716 |
| CEP350 | centrosomal protein 350kDa | -0.0263285 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0262901 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.026288 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0261268 |
| TMSB4X | thymosin beta 4, X-linked | -0.025724 |
| RBM39 | RNA binding motif protein 39 | -0.0257206 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | -0.0257182 |
| ZNF148 | zinc finger protein 148 | -0.0252389 |
| ZNF292 | zinc finger protein 292 | -0.0250119 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0248772 |
| FAM13A | family with sequence similarity 13, member A | -0.0244262 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0241301 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0240812 |
| ECT2 | epithelial cell transforming 2 | -0.023979 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0236725 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0235815 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0234366 |
| FAM3C | family with sequence similarity 3, member C | -0.0234047 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0229301 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0228941 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | -0.0227729 |
| SETD5 | SET domain containing 5 | -0.0223845 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.022228 |
| PPP4R3A | protein phosphatase 4 regulatory subunit 3A | -0.0220169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.021931 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0218176 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0217642 |
| CDC73 | cell division cycle 73 | -0.0217536 |
