| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.217767 |
| PDE10A | phosphodiesterase 10A | 0.183131 |
| DST | dystonin | 0.160731 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.101791 |
| KYNU | kynureninase | 0.0990293 |
| COL5A2 | collagen, type V, alpha 2 | 0.0954648 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0912146 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0863089 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0852056 |
| GRAMD1B | GRAM domain containing 1B | 0.0786147 |
| ASPH | aspartate beta-hydroxylase | 0.0779532 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0721956 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.069024 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0674502 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0671301 |
| FMNL2 | formin-like 2 | 0.0659257 |
| GDA | guanine deaminase | 0.0648452 |
| MCL1 | myeloid cell leukemia 1 | 0.0639247 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0625805 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0588594 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0580986 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0578106 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0555202 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0551337 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0479207 |
| EZR | ezrin | 0.0463739 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0459751 |
| MYOF | myoferlin | 0.045423 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0445525 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0437397 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0437346 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0425994 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0423784 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.042268 |
| PRELID2 | PRELI domain containing 2 | 0.041452 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0403631 |
| CTBP2 | C-terminal binding protein 2 | 0.0403204 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0394345 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0390258 |
| PKM | pyruvate kinase, muscle | 0.0388468 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0386483 |
| ENO1 | enolase 1, (alpha) | 0.0383637 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0369726 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0365559 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0357015 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0349014 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0348455 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0347415 |
| RPL41 | ribosomal protein L41 | 0.0345608 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0343878 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0343503 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0336126 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0335403 |
| INTS6 | integrator complex subunit 6 | 0.0332666 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0318028 |
| ZNF638 | zinc finger protein 638 | 0.0316746 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0314962 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0311096 |
| HDAC4 | histone deacetylase 4 | 0.0308452 |
| GPHN | gephyrin | 0.030672 |
| FAT1 | FAT atypical cadherin 1 | 0.0295414 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0294562 |
| TPR | translocated promoter region, nuclear basket protein | 0.0294377 |
| BMP6 | bone morphogenetic protein 6 | 0.0288352 |
| SQSTM1 | sequestosome 1 | 0.0286147 |
| CEP72 | centrosomal protein 72kDa | 0.0285347 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0282797 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0281147 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0280112 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0279671 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0273402 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0272792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0265417 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0259602 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0258013 |
| EXT1 | exostosin glycosyltransferase 1 | 0.025602 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0255937 |
| RPL37A | ribosomal protein L37a | 0.0254231 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0253904 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0253816 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0252616 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0252042 |
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.0251618 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0251542 |
| CLTC | clathrin, heavy chain (Hc) | 0.0249286 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0249229 |
| EPHA4 | EPH receptor A4 | 0.0245076 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0244992 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0243058 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0242561 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0242014 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0239706 |
| FAM107B | family with sequence similarity 107, member B | 0.0237666 |
| GOLGB1 | golgin B1 | 0.0235169 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0235013 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0234324 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0233718 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0233 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0232429 |
| CALR | calreticulin | 0.0232061 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.275238 |
| FN1 | fibronectin 1 | -0.230659 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.178529 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.090145 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0883252 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0877915 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0849029 |
| VIM | vimentin | -0.0813706 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0760716 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0739234 |
| TMSB10 | thymosin beta 10 | -0.0701263 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0612233 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0517911 |
| S100A6 | S100 calcium binding protein A6 | -0.051683 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0504619 |
| FTL | ferritin, light polypeptide | -0.046934 |
| NRCAM | neuronal cell adhesion molecule | -0.0456559 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0440401 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0439764 |
| STC1 | stanniocalcin 1 | -0.0431723 |
| NCKAP5 | NCK-associated protein 5 | -0.0425969 |
| SRGN | serglycin | -0.0406929 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0389456 |
| GNAS | GNAS complex locus | -0.0370152 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352152 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0342169 |
| SLC16A6 | solute carrier family 16, member 6 | -0.0333736 |
| CDH13 | cadherin 13 | -0.032856 |
| PCBP3 | poly(rC) binding protein 3 | -0.0320941 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0319362 |
| TMX4 | thioredoxin-related transmembrane protein 4 | -0.0316117 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0314886 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0312877 |
| S100A10 | S100 calcium binding protein A10 | -0.0311593 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0301002 |
| RTN4 | reticulon 4 | -0.0296674 |
| SBF2 | SET binding factor 2 | -0.0296115 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.02961 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0289786 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0285688 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0282603 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0280564 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0271646 |
| PTGR1 | prostaglandin reductase 1 | -0.0259475 |
| MFF | mitochondrial fission factor | -0.0258421 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0256307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0252125 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0242141 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0240139 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0239863 |
| PTMA | prothymosin, alpha | -0.0234329 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0231664 |
| UBC | ubiquitin C | -0.0230478 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.0226745 |
| BMERB1 | bMERB domain containing 1 | -0.0223389 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -0.0223337 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0223057 |
| MT2A | metallothionein 2A | -0.022083 |
| RPL12 | ribosomal protein L12 | -0.0219798 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0219535 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0219025 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0216947 |
| ASTN2 | astrotactin 2 | -0.0216452 |
| PFN1 | profilin 1 | -0.0213646 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0212774 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0212675 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0212384 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.0210341 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0207419 |
| FRMD4B | FERM domain containing 4B | -0.0206603 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0205796 |
| RPL39 | ribosomal protein L39 | -0.0205241 |
| HDAC8 | histone deacetylase 8 | -0.0203992 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0200461 |
| CRLF2 | cytokine receptor-like factor 2 | -0.0200067 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0199352 |
| FOXC1 | forkhead box C1 | -0.019934 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0199162 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0197436 |
| TKT | transketolase | -0.0195838 |
| PDGFA | platelet-derived growth factor alpha polypeptide | -0.0194867 |
| RACK1 | receptor for activated C kinase 1 | -0.0193631 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0192798 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0190393 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0187835 |
| FNBP1 | formin binding protein 1 | -0.0187137 |
| CXXC1 | CXXC finger protein 1 | -0.0185981 |
| B2M | beta-2-microglobulin | -0.0185544 |
| OSMR | oncostatin M receptor | -0.0184557 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0182196 |
| LAMB1 | laminin, beta 1 | -0.0180886 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0180399 |
| RPS4X | ribosomal protein S4, X-linked | -0.0179972 |
| PRKD3 | protein kinase D3 | -0.0179604 |
| MAP1B | microtubule-associated protein 1B | -0.0178385 |
| RPS24 | ribosomal protein S24 | -0.0177935 |
| TPM4 | tropomyosin 4 | -0.0177723 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0177198 |
| RPS28 | ribosomal protein S28 | -0.0175318 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0172778 |
