| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | 0.19716 |
| NTM | neurotrimin | 0.115584 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.104957 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0776622 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0771038 |
| DST | dystonin | 0.0746579 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0670886 |
| PCBP2 | poly(rC) binding protein 2 | 0.0601994 |
| CALR | calreticulin | 0.0598616 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0581404 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0551398 |
| POTEF | POTE ankyrin domain family, member F | 0.0541043 |
| LRRC4C | leucine rich repeat containing 4C | 0.0538104 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0502406 |
| RPS6 | ribosomal protein S6 | 0.0496988 |
| SRP54 | signal recognition particle 54kDa | 0.0474988 |
| ANK2 | ankyrin 2, neuronal | 0.0467504 |
| SETD5 | SET domain containing 5 | 0.0465524 |
| ENO1 | enolase 1, (alpha) | 0.046149 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0452596 |
| TENM3 | teneurin transmembrane protein 3 | 0.0442533 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0439996 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0438139 |
| FN1 | fibronectin 1 | 0.0427305 |
| PCDH9 | protocadherin 9 | 0.0425586 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0422332 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0420925 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0409503 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0397804 |
| B2M | beta-2-microglobulin | 0.0393603 |
| PFN1 | profilin 1 | 0.0392906 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0392768 |
| SNX6 | sorting nexin 6 | 0.0383213 |
| SKIL | SKI-like proto-oncogene | 0.0382102 |
| CADM2 | cell adhesion molecule 2 | 0.036872 |
| COL5A2 | collagen, type V, alpha 2 | 0.036807 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0367114 |
| TOX | thymocyte selection-associated high mobility group box | 0.036224 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0357738 |
| TMOD3 | tropomodulin 3 (ubiquitous) | 0.035299 |
| RPS12 | ribosomal protein S12 | 0.0341888 |
| PGK1 | phosphoglycerate kinase 1 | 0.0338316 |
| CFL2 | cofilin 2 (muscle) | 0.0334776 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.0331056 |
| LDHA | lactate dehydrogenase A | 0.0327692 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0319213 |
| FTL | ferritin, light polypeptide | 0.0318914 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0314255 |
| ZNF638 | zinc finger protein 638 | 0.0312271 |
| ATXN2 | ataxin 2 | 0.031138 |
| HYOU1 | hypoxia up-regulated 1 | 0.0311229 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0310168 |
| GPHN | gephyrin | 0.0309413 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.03085 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0305511 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0303791 |
| COL3A1 | collagen, type III, alpha 1 | 0.0300551 |
| BPTF | bromodomain PHD finger transcription factor | 0.0299628 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0298835 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0294351 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0293623 |
| TUBA1B | tubulin, alpha 1b | 0.0293396 |
| USP34 | ubiquitin specific peptidase 34 | 0.0293284 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0289296 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0287007 |
| PHIP | pleckstrin homology domain interacting protein | 0.02849 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0282012 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0280577 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.028021 |
| ITM2B | integral membrane protein 2B | 0.0277623 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0269893 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0262748 |
| PRKD1 | protein kinase D1 | 0.0261136 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0260572 |
| TCF12 | transcription factor 12 | 0.0260333 |
| PRTG | protogenin | 0.025839 |
| NCAM2 | neural cell adhesion molecule 2 | 0.0258323 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0255922 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0255486 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0253569 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0253413 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0252892 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0250585 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.025015 |
| ITGAV | integrin, alpha V | 0.0249132 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0247548 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.024734 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0245372 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0243084 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0242902 |
| GPC6 | glypican 6 | 0.0242632 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0241581 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0240446 |
| PPP4R2 | protein phosphatase 4, regulatory subunit 2 | 0.0239151 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0239104 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0238855 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0238243 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0238139 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.023629 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0235539 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119509 |
| THBS1 | thrombospondin 1 | -0.0819642 |
| GPC3 | glypican 3 | -0.0769658 |
| RPS16 | ribosomal protein S16 | -0.0649518 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0622735 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0576609 |
| ACTG1 | actin gamma 1 | -0.0571307 |
| PTMA | prothymosin, alpha | -0.055057 |
| HDAC9 | histone deacetylase 9 | -0.0532765 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0529384 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0465789 |
| ZNF292 | zinc finger protein 292 | -0.0464355 |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D | -0.0457933 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0442218 |
| MKI67 | marker of proliferation Ki-67 | -0.0421554 |
| RBM39 | RNA binding motif protein 39 | -0.0391421 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0385955 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0379406 |
| FAM171B | family with sequence similarity 171, member B | -0.0373211 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0368921 |
| TMSB10 | thymosin beta 10 | -0.0364457 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0362849 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0360963 |
| AHNAK | AHNAK nucleoprotein | -0.0360782 |
| CDK6 | cyclin-dependent kinase 6 | -0.0355088 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0354178 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0351937 |
| CABLES1 | Cdk5 and Abl enzyme substrate 1 | -0.0350893 |
| USP15 | ubiquitin specific peptidase 15 | -0.0339594 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0336401 |
| TAOK1 | TAO kinase 1 | -0.032098 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0316892 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0312726 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0311658 |
| RPS8 | ribosomal protein S8 | -0.0310622 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0308728 |
| RPL38 | ribosomal protein L38 | -0.0305857 |
| MDN1 | MDN1, midasin homolog (yeast) | -0.0299813 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0297966 |
| LRRN3 | leucine rich repeat neuronal 3 | -0.0295682 |
| SRP72 | signal recognition particle 72kDa | -0.0295318 |
| WDR43 | WD repeat domain 43 | -0.0294553 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0294533 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0292945 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0292506 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0290461 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0289779 |
| RHEB | Ras homolog enriched in brain | -0.0287067 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0284432 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0280351 |
| COL1A2 | collagen, type I, alpha 2 | -0.0279426 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0278356 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0277984 |
| RPL5 | ribosomal protein L5 | -0.0275865 |
| NPAS3 | neuronal PAS domain protein 3 | -0.0275726 |
| SPAG9 | sperm associated antigen 9 | -0.0275047 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0268868 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0267447 |
| RYBP | RING1 and YY1 binding protein | -0.0265301 |
| MB21D2 | Mab-21 domain containing 2 | -0.0264685 |
| GNAS | GNAS complex locus | -0.0262504 |
| COG5 | component of oligomeric golgi complex 5 | -0.0260957 |
| LIN28B | lin-28 homolog B (C. elegans) | -0.0259721 |
| OLA1 | Obg-like ATPase 1 | -0.0257665 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0257559 |
| EMP1 | epithelial membrane protein 1 | -0.0254641 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0254216 |
| POMP | proteasome maturation protein | -0.0253292 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0253223 |
| RPL19 | ribosomal protein L19 | -0.0252988 |
| RPL7 | ribosomal protein L7 | -0.0251347 |
| TFRC | transferrin receptor | -0.0250354 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0242904 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0242101 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0241912 |
| BTG3 | BTG family, member 3 | -0.0241599 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0241568 |
| RTF1 | Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | -0.0240316 |
| RDX | radixin | -0.0239299 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0238158 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0238014 |
| CERT1 | ceramide transporter 1 | -0.0235032 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0234253 |
| GPATCH8 | G patch domain containing 8 | -0.0232595 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0232308 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0229764 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.022964 |
| POU3F2 | POU class 3 homeobox 2 | -0.0228812 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0226717 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.022606 |
| ZFR | zinc finger RNA binding protein | -0.0222884 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.022103 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0219064 |
| RPL37 | ribosomal protein L37 | -0.0216928 |
| ATG5 | autophagy related 5 | -0.0215853 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0215588 |
| ACTN4 | actinin, alpha 4 | -0.0215241 |
| NRG1 | neuregulin 1 | -0.0215101 |
| PCNX4 | pecanex 4 | -0.0215065 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0214257 |
