Fusidic acid_Panc 03.27 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Fusidic acid perturbation in Panc 03.27 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Fusidic acid_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0979585
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0979276
MACF1 microtubule-actin crosslinking factor 1 0.0939424
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0909474
DSPP dentin sialophosphoprotein 0.0885822
AFDN afadin, adherens junction formation factor 0.0874799
LMO7 LIM domain 7 0.087163
EZR ezrin 0.0770741
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 0.073493
MYO5B myosin VB 0.0723222
LAMB3 laminin, beta 3 0.0713939
SMAD3 SMAD family member 3 0.0699572
TJP1 tight junction protein 1 0.0685503
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.065161
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0617282
VMP1 vacuole membrane protein 1 0.0609678
LAMC2 laminin, gamma 2 0.0606807
MYH9 myosin, heavy chain 9, non-muscle 0.058879
SIPA1L1 signal-induced proliferation-associated 1 like 1 0.0570976
SLC38A2 solute carrier family 38, member 2 0.0569529
DSCAM Down syndrome cell adhesion molecule 0.0563514
NAV2 neuron navigator 2 0.0562891
SVIL supervillin 0.055276
CD44 CD44 molecule (Indian blood group) 0.0517529
FMNL2 formin-like 2 0.0515244
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.0514437
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0509522
SH3KBP1 SH3-domain kinase binding protein 1 0.0474334
BACE2 beta-site APP-cleaving enzyme 2 0.0472421
TRIO trio Rho guanine nucleotide exchange factor 0.047046
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 0.047019
RNF213 ring finger protein 213 0.0462293
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0459615
INTS6 integrator complex subunit 6 0.0447564
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.0445509
DUSP10 dual specificity phosphatase 10 0.044491
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0441735
AKAP13 A kinase (PRKA) anchor protein 13 0.0436804
RPL41 ribosomal protein L41 0.0427613
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.0423711
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0396063
SAMD4A sterile alpha motif domain containing 4A 0.0394638
ENO1 enolase 1, (alpha) 0.0390194
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.038792
BCAR3 breast cancer anti-estrogen resistance 3 0.0386631
ACTN1 actinin, alpha 1 0.0385979
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0380716
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0379556
AREG amphiregulin 0.037947
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0375734
MYO6 myosin VI 0.0369235
MT2A metallothionein 2A 0.0365334
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.0363194
CAPRIN2 caprin family member 2 0.0359065
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0349304
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0347005
SON SON DNA binding protein 0.0346751
CTBP2 C-terminal binding protein 2 0.0340877
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0332409
ARHGAP5 Rho GTPase activating protein 5 0.0332208
APLP2 amyloid beta (A4) precursor-like protein 2 0.0326341
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0325939
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.032463
HSPA8 heat shock 70kDa protein 8 0.032434
GOLGB1 golgin B1 0.0324039
SOX9 SRY (sex determining region Y)-box 9 0.03235
RIMKLB ribosomal modification protein rimK-like family member B 0.031743
MAST4 microtubule associated serine/threonine kinase family member 4 0.031627
KLF12 Kruppel-like factor 12 0.0313858
CANX calnexin 0.0311175
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0305715
FAM107B family with sequence similarity 107, member B 0.0303471
DST dystonin 0.0299648
LAMA4 laminin, alpha 4 0.0298362
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0297894
EXT1 exostosin glycosyltransferase 1 0.0297405
ARHGAP26 Rho GTPase activating protein 26 0.0291526
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.0290998
TXNIP thioredoxin interacting protein 0.0286093
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0284097
FRMD6 FERM domain containing 6 0.0283788
RUNX1 runt-related transcription factor 1 0.0279825
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.0279723
TMF1 TATA element modulatory factor 1 0.0276222
GRB10 growth factor receptor-bound protein 10 0.0274846
YBX3 Y box binding protein 3 0.0274107
CALR calreticulin 0.0273968
DIAPH1 diaphanous-related formin 1 0.0272879
EHF ets homologous factor 0.0270776
ANO6 anoctamin 6 0.0269578
ANKRD12 ankyrin repeat domain 12 0.0260005
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.0259894
SMYD3 SET and MYND domain containing 3 0.0255538
PKM pyruvate kinase, muscle 0.0255228
ERBIN erbb2 interacting protein 0.0254773
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0254614
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.0253167
ANKRD33B ankyrin repeat domain 33B 0.0252368
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) 0.0249397
LUC7L3 LUC7-like 3 (S. cerevisiae) 0.0249062

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.410509
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.13625
MUC4 mucin 4, cell surface associated -0.122629
PTMA prothymosin, alpha -0.119064
HMGA1 high mobility group AT-hook 1 -0.106519
IGFBP3 insulin-like growth factor binding protein 3 -0.0970237
FTH1 ferritin, heavy polypeptide 1 -0.0876901
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0806736
ACTG1 actin gamma 1 -0.0770712
LY6E lymphocyte antigen 6 complex, locus E -0.0764762
TMSB10 thymosin beta 10 -0.0762187
PLAT plasminogen activator, tissue -0.072058
TPT1 tumor protein, translationally-controlled 1 -0.0660798
HLA-B major histocompatibility complex, class I, B -0.0651948
DLG1 discs, large homolog 1 (Drosophila) -0.0564335
KRT17 keratin 17, type I -0.0561702
RPS25 ribosomal protein S25 -0.0558446
KRT7 keratin 7, type II -0.0554589
RPS6 ribosomal protein S6 -0.0552682
B2M beta-2-microglobulin -0.0549638
RPS15 ribosomal protein S15 -0.0538491
TAPBP TAP binding protein (tapasin) -0.0526029
HLA-C major histocompatibility complex, class I, C -0.0523526
RPS24 ribosomal protein S24 -0.0516893
LOC112694756 uncharaterized LOC112694756 -0.0510857
TMEM123 transmembrane protein 123 -0.050323
RPS23 ribosomal protein S23 -0.0481971
C6ORF132 chromosome 6 open reading frame 132 -0.0475096
RPL28 ribosomal protein L28 -0.0474867
S100A6 S100 calcium binding protein A6 -0.04534
ANXA2 annexin A2 -0.0446213
EIF1 eukaryotic translation initiation factor 1 -0.0433536
KRT18 keratin 18, type I -0.0422948
RPL8 ribosomal protein L8 -0.0421425
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.04199
F3 coagulation factor III (thromboplastin, tissue factor) -0.0417973
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0406059
GNAS GNAS complex locus -0.0406016
RPLP1 ribosomal protein, large, P1 -0.0405063
CAV1 caveolin 1, caveolae protein, 22kDa -0.0401389
RPS5 ribosomal protein S5 -0.0395488
UGCG UDP-glucose ceramide glucosyltransferase -0.0389374
MAP3K13 mitogen-activated protein kinase kinase kinase 13 -0.0387458
HLA-E major histocompatibility complex, class I, E -0.0386432
KRT8 keratin 8, type II -0.0381982
RPS13 ribosomal protein S13 -0.0381062
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.037696
PPDPF pancreatic progenitor cell differentiation and proliferation factor -0.0366194
DAPK1 death-associated protein kinase 1 -0.0365281
RPL19 ribosomal protein L19 -0.0357512
SYT14 synaptotagmin XIV -0.0350849
UBC ubiquitin C -0.0348083
PLEKHA5 pleckstrin homology domain containing, family A member 5 -0.0345771
DPYD dihydropyrimidine dehydrogenase -0.0326303
TPM4 tropomyosin 4 -0.0323099
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -0.0322701
ATP5F1B ATP synthase F1 subunit beta -0.0318022
RPL30 ribosomal protein L30 -0.0311495
NT5C2 5'-nucleotidase, cytosolic II -0.0311318
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0307625
RPS16 ribosomal protein S16 -0.0306122
OSMR oncostatin M receptor -0.0303054
TMSB4X thymosin beta 4, X-linked -0.0302497
PARD6B par-6 family cell polarity regulator beta -0.0297478
CD2AP CD2-associated protein -0.0295754
FCHSD2 FCH and double SH3 domains 2 -0.0291805
RPL36A ribosomal protein L36a -0.0289474
EMP1 epithelial membrane protein 1 -0.0286666
RPS8 ribosomal protein S8 -0.0286289
ZNF609 zinc finger protein 609 -0.0285572
CDCP1 CUB domain containing protein 1 -0.0285417
S100A10 S100 calcium binding protein A10 -0.0283078
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0282042
MBNL2 muscleblind-like splicing regulator 2 -0.0281381
RPL11 ribosomal protein L11 -0.0276571
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0274175
PTBP3 polypyrimidine tract binding protein 3 -0.026981
NPEPPS aminopeptidase puromycin sensitive -0.0267221
TC2N tandem C2 domains, nuclear -0.0267192
RPS29 ribosomal protein S29 -0.0263539
ZFAND3 zinc finger, AN1-type domain 3 -0.0260565
FOSL1 FOS-like antigen 1 -0.0259503
ITGB4 integrin, beta 4 -0.0259386
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0256535
RPS11 ribosomal protein S11 -0.0256493
SORBS2 sorbin and SH3 domain containing 2 -0.0254306
RPS21 ribosomal protein S21 -0.0254198
DEK DEK proto-oncogene -0.0253605
WDR45B WD repeat domain 45B -0.0252897
ZDHHC20 zinc finger, DHHC-type containing 20 -0.0251287
RPL31 ribosomal protein L31 -0.0250188
CCND1 cyclin D1 -0.0247342
RACK1 receptor for activated C kinase 1 -0.0247069
RPL23 ribosomal protein L23 -0.0246315
FAU Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed -0.0246043
H3-3B H3.3 histone B -0.0243741
RPL32 ribosomal protein L32 -0.0242355
LDHA lactate dehydrogenase A -0.0241454
RPL15 ribosomal protein L15 -0.0241085
SULF2 sulfatase 2 -0.0239507