| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in RPMI-7951 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_RPMI-7951 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.169406 |
| ENO1 | enolase 1, (alpha) | 0.112218 |
| CD44 | CD44 molecule (Indian blood group) | 0.109251 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0876731 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0849409 |
| VEGFA | vascular endothelial growth factor A | 0.0837202 |
| PKM | pyruvate kinase, muscle | 0.0827096 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0780887 |
| SMAD3 | SMAD family member 3 | 0.0770718 |
| ANGPTL4 | angiopoietin-like 4 | 0.0699667 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0698658 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0695572 |
| COL6A2 | collagen, type VI, alpha 2 | 0.068815 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0668468 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0664695 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.063601 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0635193 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0625303 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0623933 |
| LDHA | lactate dehydrogenase A | 0.0595595 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0572412 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0553506 |
| ASPH | aspartate beta-hydroxylase | 0.0538805 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0537166 |
| TGM2 | transglutaminase 2 | 0.0523498 |
| FAT1 | FAT atypical cadherin 1 | 0.0521188 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.051621 |
| MT2A | metallothionein 2A | 0.0512233 |
| SVIL | supervillin | 0.0495886 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0493051 |
| NAV2 | neuron navigator 2 | 0.0493017 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0472677 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0465395 |
| HDAC9 | histone deacetylase 9 | 0.0448958 |
| CALR | calreticulin | 0.0445909 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0417981 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0412756 |
| RUNX1 | runt-related transcription factor 1 | 0.0407462 |
| IFI44L | interferon-induced protein 44-like | 0.0404317 |
| GOLGB1 | golgin B1 | 0.039775 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0395425 |
| APP | amyloid beta (A4) precursor protein | 0.0393442 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0390807 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0381529 |
| MYO1B | myosin IB | 0.0380415 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0378156 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0375182 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.037483 |
| RPS17 | ribosomal protein S17 | 0.0362305 |
| ARRDC3 | arrestin domain containing 3 | 0.036074 |
| MMP2 | matrix metallopeptidase 2 | 0.0360497 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0358527 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0352173 |
| TOP1 | topoisomerase (DNA) I | 0.035181 |
| RPS12 | ribosomal protein S12 | 0.0349293 |
| ATP13A3 | ATPase type 13A3 | 0.0348623 |
| VMP1 | vacuole membrane protein 1 | 0.0346316 |
| RPS3 | ribosomal protein S3 | 0.0345326 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0338733 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0333572 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0332269 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0325249 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0325203 |
| DST | dystonin | 0.0323707 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0319375 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0318541 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0318073 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0316293 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0311859 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0308493 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0306571 |
| IFI44 | interferon-induced protein 44 | 0.0306527 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.030498 |
| OPTN | optineurin | 0.0304787 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.030461 |
| TMEM132D | transmembrane protein 132D | 0.029721 |
| H1-0 | H1.0 linker histone | 0.029544 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0292538 |
| KYNU | kynureninase | 0.0291344 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0288542 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0287498 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0284613 |
| TPM3 | tropomyosin 3 | 0.028254 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0281354 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0279926 |
| YEATS2 | YEATS domain containing 2 | 0.0274863 |
| FLNB | filamin B, beta | 0.0268473 |
| NOTCH2 | notch 2 | 0.0265671 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0262734 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0258975 |
| PCM1 | pericentriolar material 1 | 0.0256121 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0256094 |
| APCDD1L | adenomatosis polyposis coli down-regulated 1-like | 0.0253728 |
| ACTN4 | actinin, alpha 4 | 0.0252577 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0252233 |
| AFAP1 | actin filament associated protein 1 | 0.0251429 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0251006 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0250244 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0248918 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0246875 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.288998 |
| VIM | vimentin | -0.198219 |
| FN1 | fibronectin 1 | -0.186144 |
| COL1A2 | collagen, type I, alpha 2 | -0.172686 |
| HLA-B | major histocompatibility complex, class I, B | -0.124096 |
| CDH13 | cadherin 13 | -0.1036 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.102909 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0706348 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0675754 |
| TMSB10 | thymosin beta 10 | -0.0646036 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0620821 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0620753 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0620603 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0563603 |
| RRBP1 | ribosome binding protein 1 | -0.0560663 |
| TPM4 | tropomyosin 4 | -0.0554818 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0540021 |
| GNAS | GNAS complex locus | -0.0533863 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0522985 |
| HLA-C | major histocompatibility complex, class I, C | -0.0497131 |
| TNNC1 | troponin C type 1 (slow) | -0.0488589 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0485725 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0481498 |
| IER3 | immediate early response 3 | -0.0479741 |
| CALU | calumenin | -0.0469834 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0464888 |
| TNS3 | tensin 3 | -0.0445137 |
| EGR1 | early growth response 1 | -0.0437839 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0434409 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0431992 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0431023 |
| ACTG1 | actin gamma 1 | -0.0419184 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0417968 |
| PTMA | prothymosin, alpha | -0.0414254 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0406192 |
| NAV1 | neuron navigator 1 | -0.0397499 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0393885 |
| VCAN | versican | -0.0386014 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0381466 |
| ITGA1 | integrin, alpha 1 | -0.0363706 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0352361 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | -0.0342458 |
| CAVIN1 | caveolae associated protein 1 | -0.0342401 |
| ITGA11 | integrin, alpha 11 | -0.0338299 |
| COL5A2 | collagen, type V, alpha 2 | -0.0338127 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.0335444 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0329673 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0327268 |
| RTN4 | reticulon 4 | -0.0325976 |
| CLMP | CXADR-like membrane protein | -0.0323508 |
| S100A10 | S100 calcium binding protein A10 | -0.0322405 |
| IL1B | interleukin 1, beta | -0.0319082 |
| RAI14 | retinoic acid induced 14 | -0.0317183 |
| EML5 | echinoderm microtubule associated protein like 5 | -0.0312876 |
| CA12 | carbonic anhydrase XII | -0.0305541 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0299108 |
| HECW2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 | -0.029741 |
| FTL | ferritin, light polypeptide | -0.0295778 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0295621 |
| MX2 | MX dynamin-like GTPase 2 | -0.0294669 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0294374 |
| COLEC10 | collectin sub-family member 10 (C-type lectin) | -0.029408 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 | -0.0290435 |
| SH3RF3 | SH3 domain containing ring finger 3 | -0.0289861 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0285131 |
| CAPZB | capping protein (actin filament) muscle Z-line, beta | -0.0285017 |
| XAF1 | XIAP associated factor 1 | -0.0284844 |
| NRP1 | neuropilin 1 | -0.028463 |
| DSTN | destrin (actin depolymerizing factor) | -0.0284033 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0277887 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.0277218 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0274451 |
| FRMD4A | FERM domain containing 4A | -0.0273417 |
| MMP12 | matrix metallopeptidase 12 | -0.0271241 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0270655 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0267023 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0263992 |
| OXR1 | oxidation resistance 1 | -0.0261265 |
| LMNA | lamin A/C | -0.0260886 |
| GPR173 | G protein-coupled receptor 173 | -0.0259394 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0257135 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0253593 |
| TMEM263 | transmembrane protein 263 | -0.0251553 |
| MTSS1 | metastasis suppressor 1 | -0.0250824 |
| NREP | neuronal regeneration related protein | -0.0248651 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0248481 |
| FBXO11 | F-box protein 11 | -0.0246445 |
| PXDN | peroxidasin | -0.0244757 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0241964 |
| POU2F2 | POU class 2 homeobox 2 | -0.0240384 |
| TMEM165 | transmembrane protein 165 | -0.0240315 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0239999 |
| CADM1 | cell adhesion molecule 1 | -0.023967 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.023864 |
| S100A6 | S100 calcium binding protein A6 | -0.0233444 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0232823 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0227697 |
| SBF2 | SET binding factor 2 | -0.0226127 |
| RIPOR3 | RIPOR family member 3 | -0.0225859 |
| TPM1 | tropomyosin 1 (alpha) | -0.0223344 |
