| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.282134 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.148 |
| ENO1 | enolase 1, (alpha) | 0.114818 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0999383 |
| MYOF | myoferlin | 0.0974196 |
| VEGFA | vascular endothelial growth factor A | 0.0956451 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0927541 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0870717 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0734902 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0723108 |
| SMAD3 | SMAD family member 3 | 0.0719162 |
| PKM | pyruvate kinase, muscle | 0.0699621 |
| CALR | calreticulin | 0.0685579 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0623504 |
| VCAN | versican | 0.0601703 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0535967 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0532004 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0524486 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0521418 |
| ASPH | aspartate beta-hydroxylase | 0.0511321 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0509081 |
| STC2 | stanniocalcin 2 | 0.0501122 |
| TXNIP | thioredoxin interacting protein | 0.0495098 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0490183 |
| LDHA | lactate dehydrogenase A | 0.047235 |
| HDAC9 | histone deacetylase 9 | 0.0466185 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.046379 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0460484 |
| DST | dystonin | 0.0458581 |
| ZNF292 | zinc finger protein 292 | 0.0447707 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0440816 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0435295 |
| MSN | moesin | 0.0432713 |
| CD164 | CD164 molecule, sialomucin | 0.0426972 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0407972 |
| NDRG1 | N-myc downstream regulated 1 | 0.0389957 |
| EZR | ezrin | 0.0388357 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0383263 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0379584 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0378435 |
| ADM | adrenomedullin | 0.0375736 |
| SEPTIN9 | septin 9 | 0.0375171 |
| RPS3 | ribosomal protein S3 | 0.0374064 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0367608 |
| CEP250 | centrosomal protein 250kDa | 0.0361343 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0356875 |
| FLNB | filamin B, beta | 0.0352667 |
| SLC38A2 | solute carrier family 38, member 2 | 0.034741 |
| RPL41 | ribosomal protein L41 | 0.0346335 |
| SYNJ2 | synaptojanin 2 | 0.0346144 |
| TRAM2 | translocation associated membrane protein 2 | 0.0344814 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0344788 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0340793 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0337691 |
| RPS12 | ribosomal protein S12 | 0.0335433 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0334319 |
| SMYD3 | SET and MYND domain containing 3 | 0.0332166 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0328001 |
| DSPP | dentin sialophosphoprotein | 0.0325048 |
| MCL1 | myeloid cell leukemia 1 | 0.0321369 |
| FMNL2 | formin-like 2 | 0.0317414 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0317275 |
| GPC6 | glypican 6 | 0.0308345 |
| TENM2 | teneurin transmembrane protein 2 | 0.0304369 |
| JUN | jun proto-oncogene | 0.0302693 |
| TPM3 | tropomyosin 3 | 0.0301839 |
| TXNRD1 | thioredoxin reductase 1 | 0.0300494 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0299406 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0297036 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0296802 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0293013 |
| TLN1 | talin 1 | 0.0292652 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0292106 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0289707 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0289595 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0286189 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0282198 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0281942 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0281348 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0277736 |
| SFTPA2 | surfactant protein A2 | 0.0277585 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | 0.027449 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0269159 |
| ZNF608 | zinc finger protein 608 | 0.0268749 |
| VMP1 | vacuole membrane protein 1 | 0.0265744 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0264189 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0263461 |
| PCM1 | pericentriolar material 1 | 0.0263378 |
| PCBP2 | poly(rC) binding protein 2 | 0.0260744 |
| YBX1 | Y box binding protein 1 | 0.026003 |
| ANXA2 | annexin A2 | 0.0257922 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0256622 |
| ATXN1 | ataxin 1 | 0.0255189 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.025518 |
| RUNX1 | runt-related transcription factor 1 | 0.0250225 |
| FTL | ferritin, light polypeptide | 0.0247572 |
| RPS6 | ribosomal protein S6 | 0.0247144 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0246338 |
| RAI1 | retinoic acid induced 1 | 0.0244811 |
| OPTN | optineurin | 0.0243914 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.186474 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.182789 |
| KYNU | kynureninase | -0.106975 |
| CDH13 | cadherin 13 | -0.0937691 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0918263 |
| HLA-B | major histocompatibility complex, class I, B | -0.0873218 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0804773 |
| VCL | vinculin | -0.0801957 |
| BICC1 | BicC family RNA binding protein 1 | -0.065701 |
| HLA-E | major histocompatibility complex, class I, E | -0.0649937 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0608061 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0558629 |
| NABP1 | nucleic acid binding protein 1 | -0.0547507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0530473 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0529474 |
| FNIP1 | folliculin interacting protein 1 | -0.0527605 |
| RPS24 | ribosomal protein S24 | -0.0527423 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.051227 |
| GLIS3 | GLIS family zinc finger 3 | -0.0489452 |
| IER3 | immediate early response 3 | -0.0485406 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0477712 |
| WTAP | Wilms tumor 1 associated protein | -0.0471035 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.046781 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0463676 |
| GNAS | GNAS complex locus | -0.0456324 |
| DIAPH2 | diaphanous-related formin 2 | -0.0454059 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0453813 |
| NCOA7 | nuclear receptor coactivator 7 | -0.045317 |
| FN1 | fibronectin 1 | -0.0451827 |
| IL6 | interleukin 6 | -0.0447877 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | -0.0445815 |
| HMGA2 | high mobility group AT-hook 2 | -0.0444852 |
| PALLD | palladin, cytoskeletal associated protein | -0.0438677 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0426987 |
| UBC | ubiquitin C | -0.0413008 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.040739 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0407257 |
| VIM | vimentin | -0.0405283 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0396079 |
| INHBA | inhibin, beta A | -0.0393965 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0392016 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0391952 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0391116 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.038388 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0383364 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0375829 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0375311 |
| SRGN | serglycin | -0.0363468 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0357588 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0357168 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0356505 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0348934 |
| RPS23 | ribosomal protein S23 | -0.0345389 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0344308 |
| RAI14 | retinoic acid induced 14 | -0.0329168 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.031795 |
| TPM4 | tropomyosin 4 | -0.0317563 |
| SMAD2 | SMAD family member 2 | -0.0307506 |
| CLMP | CXADR-like membrane protein | -0.0303339 |
| RPL36A | ribosomal protein L36a | -0.03002 |
| PCBP3 | poly(rC) binding protein 3 | -0.0299156 |
| IL6ST | interleukin 6 signal transducer | -0.0295509 |
| HLA-A | major histocompatibility complex, class I, A | -0.0293494 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.029327 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0293131 |
| AHI1 | Abelson helper integration site 1 | -0.0292567 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0290824 |
| OSMR | oncostatin M receptor | -0.0290252 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0290156 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0289741 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0289456 |
| SNX14 | sorting nexin 14 | -0.0288479 |
| RPS25 | ribosomal protein S25 | -0.0288362 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0287335 |
| RTN3 | reticulon 3 | -0.0285074 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0280197 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0275509 |
| FLOT1 | flotillin 1 | -0.0274414 |
| THBS1 | thrombospondin 1 | -0.0273355 |
| LRRC7 | leucine rich repeat containing 7 | -0.0272389 |
| RPLP0 | ribosomal protein, large, P0 | -0.0270748 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0267823 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0266783 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0261985 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.02611 |
| AHNAK | AHNAK nucleoprotein | -0.0256375 |
| GDF15 | growth differentiation factor 15 | -0.0256243 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0255819 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0254105 |
| PLSCR1 | phospholipid scramblase 1 | -0.0253272 |
| DCBLD1 | discoidin, CUB and LCCL domain containing 1 | -0.025223 |
| INTS6 | integrator complex subunit 6 | -0.0249928 |
| AUTS2 | autism susceptibility candidate 2 | -0.0247888 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0247877 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0246993 |
| COL1A1 | collagen, type I, alpha 1 | -0.0244975 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0242853 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0242693 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 | -0.0239105 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0238698 |
