| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fusidic acid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.375776 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119474 |
| CD44 | CD44 molecule (Indian blood group) | 0.116319 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.113426 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0877004 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0867591 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0826564 |
| PRELID2 | PRELI domain containing 2 | 0.0818873 |
| ENO1 | enolase 1, (alpha) | 0.0810311 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0794527 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.078845 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0697414 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0697361 |
| CANX | calnexin | 0.0646461 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0580785 |
| COL5A1 | collagen, type V, alpha 1 | 0.0579426 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0577727 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0562574 |
| VEGFC | vascular endothelial growth factor C | 0.0547482 |
| KYNU | kynureninase | 0.0536023 |
| FAM13A | family with sequence similarity 13, member A | 0.0532069 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0517095 |
| ASPH | aspartate beta-hydroxylase | 0.0484366 |
| SEPTIN9 | septin 9 | 0.0467648 |
| CALR | calreticulin | 0.0462248 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0456428 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.043867 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0435803 |
| AHNAK | AHNAK nucleoprotein | 0.0434418 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0431362 |
| INSIG2 | insulin induced gene 2 | 0.0415684 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0403632 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0395545 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0395233 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0388632 |
| DST | dystonin | 0.0386319 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0383386 |
| LOX | lysyl oxidase | 0.0369759 |
| ATXN1 | ataxin 1 | 0.035369 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0352637 |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.0352167 |
| INTS6 | integrator complex subunit 6 | 0.0350348 |
| ATP13A3 | ATPase type 13A3 | 0.0350198 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0347674 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0346583 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0345665 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0344793 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0344382 |
| VMP1 | vacuole membrane protein 1 | 0.0341945 |
| NRXN3 | neurexin 3 | 0.0335077 |
| HIP1 | huntingtin interacting protein 1 | 0.0332743 |
| RUNX1 | runt-related transcription factor 1 | 0.033232 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0330306 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0329915 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0321387 |
| MYO10 | myosin X | 0.0312106 |
| PKM | pyruvate kinase, muscle | 0.0309368 |
| SDC4 | syndecan 4 | 0.0307693 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0304465 |
| ARB2A | ARB2 cotranscriptional regulator A | 0.0303073 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0302571 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0302161 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0301542 |
| HAPSTR1 | HUWE1 associated protein modifying stress responses | 0.0300443 |
| SETBP1 | SET binding protein 1 | 0.0299282 |
| AOPEP | aminopeptidase O (putative) | 0.0298356 |
| SMAD3 | SMAD family member 3 | 0.0296803 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0296012 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0290137 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0289319 |
| MYOF | myoferlin | 0.0285915 |
| CLTC | clathrin, heavy chain (Hc) | 0.0285449 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0282103 |
| GOLGB1 | golgin B1 | 0.0280888 |
| THBS1 | thrombospondin 1 | 0.0278372 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.027388 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0270749 |
| PYGL | phosphorylase, glycogen, liver | 0.0270064 |
| PTK2 | protein tyrosine kinase 2 | 0.026926 |
| GOLGA4 | golgin A4 | 0.0268876 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0266216 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0265165 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0264813 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0262184 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0261655 |
| ZNF292 | zinc finger protein 292 | 0.0261027 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0258111 |
| SEC24D | SEC24 family member D | 0.0252985 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0252728 |
| ANO6 | anoctamin 6 | 0.0251541 |
| ANXA2 | annexin A2 | 0.0249552 |
| FAM107B | family with sequence similarity 107, member B | 0.0246412 |
| ACTN4 | actinin, alpha 4 | 0.0245188 |
| LDHA | lactate dehydrogenase A | 0.0244247 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0243437 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0243258 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0241577 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0240905 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0238875 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.023853 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.227527 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.144374 |
| HLA-B | major histocompatibility complex, class I, B | -0.118286 |
| B2M | beta-2-microglobulin | -0.103911 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0945444 |
| TMSB10 | thymosin beta 10 | -0.0939948 |
| FTL | ferritin, light polypeptide | -0.0932085 |
| COL1A1 | collagen, type I, alpha 1 | -0.0769889 |
| MT2A | metallothionein 2A | -0.0663869 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0616126 |
| VIM | vimentin | -0.0565272 |
| PTMA | prothymosin, alpha | -0.0467398 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0465009 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0444152 |
| ACTG1 | actin gamma 1 | -0.0428972 |
| H3-3B | H3.3 histone B | -0.0420827 |
| COL1A2 | collagen, type I, alpha 2 | -0.0414186 |
| HLA-C | major histocompatibility complex, class I, C | -0.040975 |
| MYADM | myeloid-associated differentiation marker | -0.0377081 |
| RPS14 | ribosomal protein S14 | -0.0376977 |
| HLA-A | major histocompatibility complex, class I, A | -0.0373342 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0363045 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0362852 |
| CCNI | cyclin I | -0.0359966 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0354649 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0352333 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0349791 |
| RPL34 | ribosomal protein L34 | -0.0329614 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.032635 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0323434 |
| POTEF | POTE ankyrin domain family, member F | -0.0321281 |
| IL6 | interleukin 6 | -0.0313592 |
| RPL28 | ribosomal protein L28 | -0.0300582 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0300436 |
| MT1X | metallothionein 1X | -0.0292447 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0284865 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0284853 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0276583 |
| NDRG1 | N-myc downstream regulated 1 | -0.0275943 |
| TNS3 | tensin 3 | -0.0274743 |
| COL5A2 | collagen, type V, alpha 2 | -0.0272211 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0262578 |
| BBX | bobby sox homolog (Drosophila) | -0.0258285 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0257256 |
| RPLP1 | ribosomal protein, large, P1 | -0.0249182 |
| S100A6 | S100 calcium binding protein A6 | -0.0246776 |
| GNAS | GNAS complex locus | -0.0243035 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0237536 |
| FOSL1 | FOS-like antigen 1 | -0.0236483 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0235203 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0233955 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.0233271 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0233069 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0231987 |
| BSG | basigin (Ok blood group) | -0.0228578 |
| SERF2 | small EDRK-rich factor 2 | -0.0227947 |
| AK1 | adenylate kinase 1 | -0.0226053 |
| MMP12 | matrix metallopeptidase 12 | -0.0224989 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0221027 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0216897 |
| TOMM7 | translocase of outer mitochondrial membrane 7 homolog (yeast) | -0.0215421 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0215246 |
| RPL9 | ribosomal protein L9 | -0.0213905 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0213541 |
| PTN | pleiotrophin | -0.0211414 |
| SEPTIN7 | septin 7 | -0.0210805 |
| RPS23 | ribosomal protein S23 | -0.0210521 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0208855 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0208668 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0207916 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0207576 |
| CST3 | cystatin C | -0.0206663 |
| EFHD2 | EF-hand domain family, member D2 | -0.0204948 |
| EGR1 | early growth response 1 | -0.0204899 |
| S100A9 | S100 calcium binding protein A9 | -0.0203659 |
| TCERG1 | transcription elongation regulator 1 | -0.020149 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0198684 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0195843 |
| HM13 | histocompatibility (minor) 13 | -0.0195075 |
| CENPE | centromere protein E, 312kDa | -0.0194867 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0194766 |
| HMGB1 | high mobility group box 1 | -0.0194609 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0194031 |
| TUBA1B | tubulin, alpha 1b | -0.0192633 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0191277 |
| RPL27A | ribosomal protein L27a | -0.0189864 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.0189175 |
| RPS11 | ribosomal protein S11 | -0.0183117 |
| SF3B3 | splicing factor 3b, subunit 3, 130kDa | -0.0182779 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.018248 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0182083 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | -0.0182022 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0181273 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0178775 |
| RPL23 | ribosomal protein L23 | -0.0177312 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0176503 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0175637 |
| SRPK2 | SRSF protein kinase 2 | -0.0174927 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0174836 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0174774 |