| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FNDC3B | fibronectin type III domain containing 3B | 0.129389 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0923375 |
| SMAD3 | SMAD family member 3 | 0.0811698 |
| DST | dystonin | 0.0806654 |
| FMNL2 | formin-like 2 | 0.0801887 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0756311 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0742792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0720405 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.07156 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0631458 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0626051 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0601973 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0578711 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0538974 |
| CAPRIN2 | caprin family member 2 | 0.0530729 |
| GPC5 | glypican 5 | 0.0510295 |
| ANO6 | anoctamin 6 | 0.048788 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0471711 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0463336 |
| RNF213 | ring finger protein 213 | 0.0460098 |
| TXNIP | thioredoxin interacting protein | 0.0450645 |
| FLNB | filamin B, beta | 0.0448653 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0419486 |
| CANX | calnexin | 0.0390447 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0390343 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.038146 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0380862 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0364591 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0363243 |
| MYOF | myoferlin | 0.036032 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0355951 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.035453 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0354207 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03388 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0332946 |
| EGFR | epidermal growth factor receptor | 0.033234 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0331373 |
| ACTN1 | actinin, alpha 1 | 0.032872 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0326174 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0325389 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.032262 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0320745 |
| SASH1 | SAM and SH3 domain containing 1 | 0.0319724 |
| CEP250 | centrosomal protein 250kDa | 0.0317586 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0315366 |
| AFDN | afadin, adherens junction formation factor | 0.0315029 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0314559 |
| SDC4 | syndecan 4 | 0.0307453 |
| JMJD1C | jumonji domain containing 1C | 0.0307389 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0305922 |
| MYO9A | myosin IXA | 0.0303756 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0303263 |
| NGLY1 | N-glycanase 1 | 0.0301708 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0300189 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0299659 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.029932 |
| FMN1 | formin 1 | 0.0296904 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0296689 |
| ANGPTL4 | angiopoietin-like 4 | 0.0294129 |
| FN1 | fibronectin 1 | 0.0293748 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0292866 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0291925 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0291221 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0285438 |
| PARD3 | par-3 family cell polarity regulator | 0.0282776 |
| ATM | ATM serine/threonine kinase | 0.0279146 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0277887 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0273822 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0270143 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0268232 |
| APP | amyloid beta (A4) precursor protein | 0.0265067 |
| MYO9B | myosin IXB | 0.0263422 |
| ANXA1 | annexin A1 | 0.0262726 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0258487 |
| SVIL | supervillin | 0.0258201 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0256834 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0256457 |
| EXT1 | exostosin glycosyltransferase 1 | 0.025399 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0252522 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0248593 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.024735 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0246821 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0244031 |
| SMYD3 | SET and MYND domain containing 3 | 0.0240919 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0239807 |
| LAMB1 | laminin, beta 1 | 0.0237533 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0237188 |
| RAD51B | RAD51 paralog B | 0.0236936 |
| RIN2 | Ras and Rab interactor 2 | 0.0235864 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0235001 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0234678 |
| CMIP | c-Maf inducing protein | 0.0231328 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0231326 |
| HDAC9 | histone deacetylase 9 | 0.0229822 |
| DTNA | dystrobrevin, alpha | 0.022756 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0226592 |
| ATP13A3 | ATPase type 13A3 | 0.0222884 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0220784 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0220576 |
| CD163L1 | CD163 molecule-like 1 | 0.0219625 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.465937 |
| VIM | vimentin | -0.129515 |
| PTMA | prothymosin, alpha | -0.0930219 |
| TMSB10 | thymosin beta 10 | -0.0622912 |
| ZNF292 | zinc finger protein 292 | -0.0527545 |
| RPL23 | ribosomal protein L23 | -0.0484465 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0484128 |
| GNAS | GNAS complex locus | -0.0476879 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0459601 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0440154 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0437713 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0417242 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0415803 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0399028 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.03936 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0363846 |
| RACK1 | receptor for activated C kinase 1 | -0.0362014 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0360623 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0355745 |
| CREBRF | CREB3 regulatory factor | -0.0354048 |
| RBM39 | RNA binding motif protein 39 | -0.0345624 |
| TUBA1B | tubulin, alpha 1b | -0.0339087 |
| DEK | DEK proto-oncogene | -0.0334465 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0329448 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0329398 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0329276 |
| H3-3B | H3.3 histone B | -0.0329023 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0327424 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.032495 |
| UBC | ubiquitin C | -0.0320722 |
| PCBP2 | poly(rC) binding protein 2 | -0.031453 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0313444 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0310976 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0309863 |
| GOLGA4 | golgin A4 | -0.0303864 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0303016 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.030207 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.029981 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0298497 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0295529 |
| TPX2 | TPX2, microtubule-associated | -0.0294614 |
| RPL32 | ribosomal protein L32 | -0.0294087 |
| DIAPH3 | diaphanous-related formin 3 | -0.0287977 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0283348 |
| RPS13 | ribosomal protein S13 | -0.0282227 |
| RPS20 | ribosomal protein S20 | -0.0279852 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.027746 |
| DDX46 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 | -0.027592 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -0.0273542 |
| RPS27 | ribosomal protein S27 | -0.0273496 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0272615 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0269072 |
| HMGA1 | high mobility group AT-hook 1 | -0.0265626 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0265335 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0262098 |
| CUL5 | cullin 5 | -0.0261502 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0261322 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0260025 |
| RPS12 | ribosomal protein S12 | -0.02593 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0257956 |
| TOP1 | topoisomerase (DNA) I | -0.0256584 |
| RPL27A | ribosomal protein L27a | -0.0254079 |
| VDAC1 | voltage-dependent anion channel 1 | -0.025388 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0252902 |
| S100A9 | S100 calcium binding protein A9 | -0.0251975 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250698 |
| RABGAP1 | RAB GTPase activating protein 1 | -0.0250105 |
| RPL35A | ribosomal protein L35a | -0.0250048 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0249833 |
| RPS8 | ribosomal protein S8 | -0.0244802 |
| RPL9 | ribosomal protein L9 | -0.0243178 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0242734 |
| BRD2 | bromodomain containing 2 | -0.024152 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0239534 |
| CCNI | cyclin I | -0.0238486 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0238385 |
| POTEF | POTE ankyrin domain family, member F | -0.023781 |
| XRN2 | 5'-3' exoribonuclease 2 | -0.0236576 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0236327 |
| RPL35 | ribosomal protein L35 | -0.0236289 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.023448 |
| HLA-C | major histocompatibility complex, class I, C | -0.0233435 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0232968 |
| RPL26 | ribosomal protein L26 | -0.0232379 |
| HMGA2 | high mobility group AT-hook 2 | -0.0232195 |
| RPL12 | ribosomal protein L12 | -0.0231821 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0231813 |
| RPS25 | ribosomal protein S25 | -0.0229051 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0228695 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.022707 |
| ZNF207 | zinc finger protein 207 | -0.0224376 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0224084 |
| TPI1 | triosephosphate isomerase 1 | -0.0223309 |
| RPS23 | ribosomal protein S23 | -0.0222847 |
| ZBTB43 | zinc finger and BTB domain containing 43 | -0.02226 |
| IPO7 | importin 7 | -0.0221894 |
| RRBP1 | ribosome binding protein 1 | -0.0221375 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0220612 |
| HM13 | histocompatibility (minor) 13 | -0.0220153 |
| RPS6 | ribosomal protein S6 | -0.0219564 |
