| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fusidic acid perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fusidic acid_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.185938 |
| HMGA2 | high mobility group AT-hook 2 | 0.173781 |
| STC1 | stanniocalcin 1 | 0.158252 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.154297 |
| INHBA | inhibin, beta A | 0.146302 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.105547 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0974624 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0917419 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0893961 |
| ASPH | aspartate beta-hydroxylase | 0.0830196 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.068775 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0685418 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0679669 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0646485 |
| EXT1 | exostosin glycosyltransferase 1 | 0.064494 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.063704 |
| LOX | lysyl oxidase | 0.0630889 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0615057 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0597488 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0581648 |
| CANX | calnexin | 0.0575043 |
| LDHA | lactate dehydrogenase A | 0.0544263 |
| ENO1 | enolase 1, (alpha) | 0.054048 |
| FNDC3B | fibronectin type III domain containing 3B | 0.053124 |
| MMP1 | matrix metallopeptidase 1 | 0.0519327 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0454732 |
| VCL | vinculin | 0.0432314 |
| NOTCH2 | notch 2 | 0.0423483 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0420175 |
| AHNAK | AHNAK nucleoprotein | 0.0415579 |
| HLA-B | major histocompatibility complex, class I, B | 0.0415577 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0408559 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0394491 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0391052 |
| CALR | calreticulin | 0.0380722 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0377972 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0377917 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0371577 |
| ACTN1 | actinin, alpha 1 | 0.0369317 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0367536 |
| PALLD | palladin, cytoskeletal associated protein | 0.0361078 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0360111 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0359514 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0354746 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0345873 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0345076 |
| HDAC9 | histone deacetylase 9 | 0.0340123 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0337457 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0335125 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0334285 |
| KIAA1217 | KIAA1217 | 0.032709 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0325643 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0321167 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0310739 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0310599 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0306748 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0301886 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.0296746 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0292878 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0292777 |
| INTS6 | integrator complex subunit 6 | 0.0281807 |
| FMNL2 | formin-like 2 | 0.0281771 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0279782 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0279563 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0277278 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0276878 |
| SMAD3 | SMAD family member 3 | 0.0276113 |
| GOLGB1 | golgin B1 | 0.0275577 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0263561 |
| FSTL1 | follistatin-like 1 | 0.026199 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0261879 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0261498 |
| TLN1 | talin 1 | 0.0253559 |
| PKM | pyruvate kinase, muscle | 0.0251404 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0250797 |
| PRELID2 | PRELI domain containing 2 | 0.0250238 |
| NABP1 | nucleic acid binding protein 1 | 0.0249869 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0249248 |
| EGFR | epidermal growth factor receptor | 0.0248713 |
| GLRX | glutaredoxin (thioltransferase) | 0.0246598 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0246107 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0244256 |
| SERINC1 | serine incorporator 1 | 0.0244125 |
| PHF3 | PHD finger protein 3 | 0.0241986 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0241744 |
| SFTPA2 | surfactant protein A2 | 0.0241453 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0241449 |
| FAT1 | FAT atypical cadherin 1 | 0.0240163 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0234725 |
| MYO1D | myosin ID | 0.0231607 |
| TOP1 | topoisomerase (DNA) I | 0.0231465 |
| C3ORF52 | chromosome 3 open reading frame 52 | 0.0228986 |
| STC2 | stanniocalcin 2 | 0.0225909 |
| RAB31 | RAB31, member RAS oncogene family | 0.0225334 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0222442 |
| ADIPOR2 | adiponectin receptor 2 | 0.0221786 |
| ANO6 | anoctamin 6 | 0.0220076 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0218763 |
| TPR | translocated promoter region, nuclear basket protein | 0.0217499 |
| IER3 | immediate early response 3 | 0.0217354 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.175099 |
| OXR1 | oxidation resistance 1 | -0.151747 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.149898 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137572 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.101543 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0963913 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0954757 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0833989 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0820026 |
| FAM13A | family with sequence similarity 13, member A | -0.0756397 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0729048 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0653599 |
| ATP13A3 | ATPase type 13A3 | -0.0636391 |
| TMEM165 | transmembrane protein 165 | -0.0560782 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0548386 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0532091 |
| TMSB10 | thymosin beta 10 | -0.0527507 |
| GOLGA4 | golgin A4 | -0.0512954 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0504026 |
| MYO10 | myosin X | -0.0501067 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0426237 |
| PRRX1 | paired related homeobox 1 | -0.0421314 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0416988 |
| MMP12 | matrix metallopeptidase 12 | -0.0401127 |
| COL1A1 | collagen, type I, alpha 1 | -0.0398007 |
| CLMP | CXADR-like membrane protein | -0.039519 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0388217 |
| MEIS1 | Meis homeobox 1 | -0.0380648 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0375388 |
| GPHN | gephyrin | -0.0366697 |
| CDH13 | cadherin 13 | -0.0359866 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.035347 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0348874 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0346248 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0343861 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.033974 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0339075 |
| PDE8A | phosphodiesterase 8A | -0.033354 |
| ITGA1 | integrin, alpha 1 | -0.0325455 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0325328 |
| USP3 | ubiquitin specific peptidase 3 | -0.0317425 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0314768 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.031469 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0310669 |
| NDRG1 | N-myc downstream regulated 1 | -0.0303391 |
| MAP4 | microtubule-associated protein 4 | -0.0300173 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0299389 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0298127 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0295869 |
| VCAN | versican | -0.0287645 |
| COL1A2 | collagen, type I, alpha 2 | -0.0285234 |
| SBF2 | SET binding factor 2 | -0.0284016 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0280551 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0274334 |
| GLI2 | GLI family zinc finger 2 | -0.0269055 |
| S100A6 | S100 calcium binding protein A6 | -0.0268707 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0264894 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0263039 |
| NPTX1 | neuronal pentraxin I | -0.0262582 |
| PLPP3 | phospholipid phosphatase 3 | -0.0262236 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0260652 |
| PCDH9 | protocadherin 9 | -0.0259796 |
| ARHGAP10 | Rho GTPase activating protein 10 | -0.0258702 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0255459 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0252724 |
| HHIP | hedgehog interacting protein | -0.0252651 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0252576 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0252342 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0251783 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0247008 |
| PFN1 | profilin 1 | -0.0246917 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0243177 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0243153 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0240508 |
| CCDC102B | coiled-coil domain containing 102B | -0.0240208 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.023844 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0235801 |
| ANO10 | anoctamin 10 | -0.0233577 |
| EBF1 | early B-cell factor 1 | -0.0233011 |
| COL5A3 | collagen, type V, alpha 3 | -0.0231382 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0230816 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0230485 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0229562 |
| FTL | ferritin, light polypeptide | -0.0228637 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0223499 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0223234 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0222375 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0222327 |
| PTMA | prothymosin, alpha | -0.0221839 |
| TENM3 | teneurin transmembrane protein 3 | -0.0221734 |
| RNF145 | ring finger protein 145 | -0.022156 |
| BNC2 | basonuclin 2 | -0.0220758 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0219778 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.021971 |
| RAI14 | retinoic acid induced 14 | -0.0216787 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0216421 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0215648 |
| PRSS23 | protease, serine, 23 | -0.0214339 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0214168 |
| RPS23 | ribosomal protein S23 | -0.0212945 |
