| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TLE4 | transducin-like enhancer of split 4 | 0.0596956 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0428674 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0383908 |
| COL1A1 | collagen, type I, alpha 1 | 0.0291495 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0278141 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0276671 |
| NEK7 | NIMA-related kinase 7 | 0.0261897 |
| VGF | VGF nerve growth factor inducible | 0.0251216 |
| RIGI | RNA sensor RIG-I | 0.0251184 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0246728 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.024633 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0236027 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0224946 |
| AOPEP | aminopeptidase O (putative) | 0.0221098 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.020354 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0201945 |
| PRPF8 | pre-mRNA processing factor 8 | 0.019969 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0197037 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.018619 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0182826 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0182761 |
| TBX2 | T-box 2 | 0.0182483 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0180379 |
| SEC24D | SEC24 family member D | 0.0174165 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0173331 |
| THOC2 | THO complex 2 | 0.0173225 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0173143 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0172703 |
| MYO6 | myosin VI | 0.0170999 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) | 0.0169882 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.01697 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.016474 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0161563 |
| MX2 | MX dynamin-like GTPase 2 | 0.0161125 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0158281 |
| SPAG9 | sperm associated antigen 9 | 0.0157309 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0155274 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0152707 |
| SEPTIN9 | septin 9 | 0.0151814 |
| AMOTL1 | angiomotin like 1 | 0.0151195 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0150223 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0148967 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 | 0.0148599 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0147746 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0146037 |
| HAS2 | hyaluronan synthase 2 | 0.0142847 |
| FAM107B | family with sequence similarity 107, member B | 0.0142003 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.014085 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0140338 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0139087 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0138975 |
| PPP1R15B | protein phosphatase 1, regulatory subunit 15B | 0.01388 |
| FLNB | filamin B, beta | 0.0136907 |
| SON | SON DNA binding protein | 0.0136799 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0136298 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0135738 |
| HMGB2 | high mobility group box 2 | 0.0134839 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0134189 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0133947 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.0133597 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0132381 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0131727 |
| ADD1 | adducin 1 (alpha) | 0.0131106 |
| PKM | pyruvate kinase, muscle | 0.0130979 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0130959 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0130755 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0130047 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0129909 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0127417 |
| PREPL | prolyl endopeptidase-like | 0.0127314 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.0126386 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0124278 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.0124233 |
| GOLGA2 | golgin A2 | 0.0123877 |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.0123204 |
| PCNX1 | pecanex 1 | 0.0123077 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.012238 |
| RBM5 | RNA binding motif protein 5 | 0.012078 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit | 0.0120709 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.012063 |
| INTS2 | integrator complex subunit 2 | 0.0119783 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0119589 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0118844 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0118678 |
| YAP1 | Yes-associated protein 1 | 0.0118671 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0118406 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0118091 |
| CDC73 | cell division cycle 73 | 0.011782 |
| FAT4 | FAT atypical cadherin 4 | 0.011742 |
| KLHL13 | kelch-like family member 13 | 0.0117004 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.0116948 |
| LAMA5 | laminin, alpha 5 | 0.0116915 |
| CLASP2 | cytoplasmic linker associated protein 2 | 0.0116267 |
| SMC5 | structural maintenance of chromosomes 5 | 0.0115455 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0115397 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0114992 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0114466 |
| SYNPO2 | synaptopodin 2 | 0.0114456 |
| RNF213 | ring finger protein 213 | 0.0114215 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0113499 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.532823 |
| LSAMP | limbic system-associated membrane protein | -0.185458 |
| IGF2 | insulin-like growth factor 2 | -0.147502 |
| PRKCA | protein kinase C, alpha | -0.130052 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.11702 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.105024 |
| NRG1 | neuregulin 1 | -0.104163 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0962397 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0910575 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0810596 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0783104 |
| VCL | vinculin | -0.0689492 |
| PTMA | prothymosin, alpha | -0.0672876 |
| CRH | corticotropin releasing hormone | -0.0640776 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0630916 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0627357 |
| CUX1 | cut-like homeobox 1 | -0.0618869 |
| ASPH | aspartate beta-hydroxylase | -0.0610729 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0581022 |
| ACTG1 | actin gamma 1 | -0.0562203 |
| DPH6 | diphthamine biosynthesis 6 | -0.0533364 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | -0.0505698 |
| NREP | neuronal regeneration related protein | -0.0495103 |
| MCL1 | myeloid cell leukemia 1 | -0.0472192 |
| CADM2 | cell adhesion molecule 2 | -0.0460568 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0439673 |
| SYT1 | synaptotagmin I | -0.043701 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0419893 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0419548 |
| RPS6 | ribosomal protein S6 | -0.0410497 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.04071 |
| TCF12 | transcription factor 12 | -0.0390779 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0390184 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0389519 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0387551 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0383059 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0381973 |
| CANX | calnexin | -0.0373642 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0371952 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0369789 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0364438 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.035383 |
| RPL35A | ribosomal protein L35a | -0.0347261 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0346897 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0343074 |
| MEF2A | myocyte enhancer factor 2A | -0.0339743 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0339117 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0336264 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0331219 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0330506 |
| MSI2 | musashi RNA-binding protein 2 | -0.0327527 |
| PLCB4 | phospholipase C, beta 4 | -0.0325621 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0325411 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0324027 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0322073 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0318624 |
| TRIB2 | tribbles pseudokinase 2 | -0.0318186 |
| PCDH9 | protocadherin 9 | -0.0317224 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0317215 |
| GPC5 | glypican 5 | -0.0315916 |
| CDH13 | cadherin 13 | -0.030952 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0304815 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.030274 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0296888 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0295403 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0287423 |
| MBTD1 | mbt domain containing 1 | -0.0287061 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0285902 |
| ZNF638 | zinc finger protein 638 | -0.0277 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0275142 |
| VEGFA | vascular endothelial growth factor A | -0.0274426 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0272113 |
| NDRG1 | N-myc downstream regulated 1 | -0.0271963 |
| VMP1 | vacuole membrane protein 1 | -0.0271861 |
| PLAT | plasminogen activator, tissue | -0.0271792 |
| RPS23 | ribosomal protein S23 | -0.0268916 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0265484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0265385 |
| DTNA | dystrobrevin, alpha | -0.0264013 |
| RAD51B | RAD51 paralog B | -0.0264006 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0263459 |
| RPL19 | ribosomal protein L19 | -0.0262058 |
| RPS24 | ribosomal protein S24 | -0.0260965 |
| VIM | vimentin | -0.0260497 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0260357 |
| GOLGB1 | golgin B1 | -0.0259519 |
| HMGA2 | high mobility group AT-hook 2 | -0.0258449 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0251301 |
| ATRNL1 | attractin-like 1 | -0.0247045 |
| ARMH4 | armadillo like helical domain containing 4 | -0.0243441 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0243437 |
| BPTF | bromodomain PHD finger transcription factor | -0.0240544 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0238783 |
| FRMD4A | FERM domain containing 4A | -0.0235576 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0234389 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.023405 |
| ENO1 | enolase 1, (alpha) | -0.0233517 |
| RNF150 | ring finger protein 150 | -0.0233 |
| PCDH11Y | protocadherin 11 Y-linked | -0.0231567 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0231029 |
