| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | 0.123225 |
| COL6A3 | collagen, type VI, alpha 3 | 0.120893 |
| STC1 | stanniocalcin 1 | 0.0937615 |
| COL5A1 | collagen, type V, alpha 1 | 0.0935561 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0728522 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0676924 |
| LOXL2 | lysyl oxidase-like 2 | 0.0664176 |
| CAVIN1 | caveolae associated protein 1 | 0.0560383 |
| MT2A | metallothionein 2A | 0.0540773 |
| LOX | lysyl oxidase | 0.0501708 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0460502 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0412107 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0411588 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0370366 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0360827 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0356196 |
| APP | amyloid beta (A4) precursor protein | 0.0347354 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0328266 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.031865 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0300211 |
| CALU | calumenin | 0.0295837 |
| MYO10 | myosin X | 0.0287548 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0283087 |
| CLMP | CXADR-like membrane protein | 0.0282513 |
| CTSB | cathepsin B | 0.0276699 |
| COL1A2 | collagen, type I, alpha 2 | 0.0274545 |
| SDC2 | syndecan 2 | 0.0269774 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0265236 |
| HMGA2 | high mobility group AT-hook 2 | 0.0263355 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0259798 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0259723 |
| OSMR | oncostatin M receptor | 0.0250934 |
| MT1X | metallothionein 1X | 0.0249821 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0246182 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0245979 |
| KLF6 | Kruppel-like factor 6 | 0.0245721 |
| GANAB | glucosidase, alpha; neutral AB | 0.0244926 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0240912 |
| COL3A1 | collagen, type III, alpha 1 | 0.0233016 |
| CD44 | CD44 molecule (Indian blood group) | 0.0231476 |
| NAV1 | neuron navigator 1 | 0.0229164 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0228006 |
| FAM20C | family with sequence similarity 20, member C | 0.0224832 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0220851 |
| RRBP1 | ribosome binding protein 1 | 0.0214007 |
| PLEC | plectin | 0.021227 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0212122 |
| RUNX1 | runt-related transcription factor 1 | 0.0210928 |
| LAMB3 | laminin, beta 3 | 0.0209823 |
| SAFB2 | scaffold attachment factor B2 | 0.0207772 |
| HAS2 | hyaluronan synthase 2 | 0.0199901 |
| MTSS1 | metastasis suppressor 1 | 0.019733 |
| ITGB5 | integrin, beta 5 | 0.0192012 |
| ARHGAP22 | Rho GTPase activating protein 22 | 0.0190618 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0187411 |
| HLA-E | major histocompatibility complex, class I, E | 0.0187122 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0186833 |
| TGFB1 | transforming growth factor, beta 1 | 0.0184929 |
| SEPTIN9 | septin 9 | 0.0183954 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0182835 |
| FLNA | filamin A, alpha | 0.0181242 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0179227 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0178767 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0175169 |
| NRP1 | neuropilin 1 | 0.016834 |
| RPL4 | ribosomal protein L4 | 0.0168041 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0167151 |
| AHNAK | AHNAK nucleoprotein | 0.0166533 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0165989 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0165696 |
| PYGL | phosphorylase, glycogen, liver | 0.0163463 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0163006 |
| GNAS | GNAS complex locus | 0.0162213 |
| SNX14 | sorting nexin 14 | 0.016147 |
| RPS2 | ribosomal protein S2 | 0.0160595 |
| RASA3 | RAS p21 protein activator 3 | 0.0160232 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0155809 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0152947 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0152695 |
| EHD2 | EH-domain containing 2 | 0.0151709 |
| DEPP1 | DEPP autophagy regulator 1 | 0.0151647 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0151119 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.0149857 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0149053 |
| PRRX1 | paired related homeobox 1 | 0.0148695 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0148195 |
| GLIS3 | GLIS family zinc finger 3 | 0.0147258 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0146133 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0146122 |
| EVI5 | ecotropic viral integration site 5 | 0.0145916 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.0145667 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0145442 |
| TUBB | tubulin, beta class I | 0.0145259 |
| SDC4 | syndecan 4 | 0.0144877 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0144577 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0142239 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.01418 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0141607 |
| EMP1 | epithelial membrane protein 1 | 0.0140704 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0137781 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.444254 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.260928 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.173314 |
| FN1 | fibronectin 1 | -0.156972 |
| FNDC3B | fibronectin type III domain containing 3B | -0.111882 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0974977 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.082435 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0810745 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0779285 |
| IL6ST | interleukin 6 signal transducer | -0.0691539 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0665561 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0660733 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0653641 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0574942 |
| BBX | bobby sox homolog (Drosophila) | -0.0564053 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0542013 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0532251 |
| GOLGA4 | golgin A4 | -0.053083 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0526932 |
| PTMA | prothymosin, alpha | -0.0524636 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.052333 |
| VEGFA | vascular endothelial growth factor A | -0.0513242 |
| CADM1 | cell adhesion molecule 1 | -0.050242 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0459706 |
| TFG | TRK-fused gene | -0.0439166 |
| TRAM1 | translocation associated membrane protein 1 | -0.0436667 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0410919 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.040002 |
| PRELID2 | PRELI domain containing 2 | -0.0396652 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0393138 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.039237 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0390276 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.038267 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0380772 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0377221 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0368575 |
| VCAN | versican | -0.0362794 |
| DSTN | destrin (actin depolymerizing factor) | -0.0362604 |
| ZNF292 | zinc finger protein 292 | -0.0355697 |
| QKI | QKI, KH domain containing, RNA binding | -0.0349771 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0343476 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0342982 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0339832 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0339495 |
| CANX | calnexin | -0.0336694 |
| POSTN | periostin, osteoblast specific factor | -0.0335749 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.033408 |
| UBC | ubiquitin C | -0.033245 |
| RPS6 | ribosomal protein S6 | -0.0324752 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0324015 |
| DST | dystonin | -0.0320595 |
| ATXN1 | ataxin 1 | -0.0320288 |
| B2M | beta-2-microglobulin | -0.0318632 |
| HYOU1 | hypoxia up-regulated 1 | -0.0315525 |
| GOLGB1 | golgin B1 | -0.0314733 |
| RPL35A | ribosomal protein L35a | -0.0313569 |
| ENO1 | enolase 1, (alpha) | -0.0312547 |
| COL6A1 | collagen, type VI, alpha 1 | -0.031016 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0307985 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.030661 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0306031 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0302199 |
| YBX1 | Y box binding protein 1 | -0.0300398 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0298858 |
| S100A9 | S100 calcium binding protein A9 | -0.0298814 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.029808 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0296858 |
| HDAC9 | histone deacetylase 9 | -0.0293519 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0293191 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0292959 |
| POTEF | POTE ankyrin domain family, member F | -0.0288558 |
| COPA | coatomer protein complex, subunit alpha | -0.0287229 |
| DOCK7 | dedicator of cytokinesis 7 | -0.0283117 |
| PGM3 | phosphoglucomutase 3 | -0.0278484 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0275685 |
| PFN1 | profilin 1 | -0.0272149 |
| MTDH | metadherin | -0.0271753 |
| ACTG1 | actin gamma 1 | -0.0270784 |
| TENM3 | teneurin transmembrane protein 3 | -0.0270131 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0269546 |
| ARF4 | ADP-ribosylation factor 4 | -0.0268267 |
| EGR1 | early growth response 1 | -0.0267041 |
| SETD5 | SET domain containing 5 | -0.0263583 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0258688 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0257873 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0257026 |
| SEPTIN7 | septin 7 | -0.0256746 |
| TMSB4X | thymosin beta 4, X-linked | -0.0256604 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0256384 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0254829 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0253733 |
| CALD1 | caldesmon 1 | -0.0253644 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | -0.0253318 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0252843 |
| WASF2 | WAS protein family, member 2 | -0.0250044 |
| FTL | ferritin, light polypeptide | -0.0249597 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0248265 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0247487 |
| CCDC80 | coiled-coil domain containing 80 | -0.0243311 |
| FBXO32 | F-box protein 32 | -0.0243284 |
