| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ONECUT3 | one cut homeobox 3 | 0.0731805 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0365227 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0296183 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0294909 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0293344 |
| VCL | vinculin | 0.02043 |
| IER3 | immediate early response 3 | 0.0202304 |
| MYO1E | myosin IE | 0.0191695 |
| H1-0 | H1.0 linker histone | 0.0183131 |
| TNS4 | tensin 4 | 0.0178713 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0162698 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0157064 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0153116 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0147527 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0140097 |
| MYH14 | myosin, heavy chain 14, non-muscle | 0.0137816 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0135096 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | 0.012586 |
| AREG | amphiregulin | 0.0124129 |
| CMIP | c-Maf inducing protein | 0.0122609 |
| HNRNPAB | heterogeneous nuclear ribonucleoprotein A/B | 0.0117952 |
| CUX1 | cut-like homeobox 1 | 0.0117336 |
| MUC13 | mucin 13, cell surface associated | 0.0114657 |
| LAMA4 | laminin, alpha 4 | 0.0111045 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0109356 |
| IGF2 | insulin-like growth factor 2 | 0.0109139 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0108532 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0107721 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0106764 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0103642 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0102902 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0102344 |
| KPNB1 | karyopherin (importin) beta 1 | 0.00995108 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00992675 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0098178 |
| YBX3 | Y box binding protein 3 | 0.00972427 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00970687 |
| RAD51B | RAD51 paralog B | 0.00960592 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.00940036 |
| AGRN | agrin | 0.00937682 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.00913816 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.00906426 |
| ABR | active BCR-related | 0.00870266 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00862425 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.00861311 |
| CADPS | Ca++-dependent secretion activator | 0.00842358 |
| PALLD | palladin, cytoskeletal associated protein | 0.00840354 |
| UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.00831924 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.00825792 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0081879 |
| ANTXR2 | anthrax toxin receptor 2 | 0.00816813 |
| PRSS3 | protease, serine, 3 | 0.00810999 |
| IRF3 | interferon regulatory factor 3 | 0.0080761 |
| MLPH | melanophilin | 0.00807223 |
| EPHB2 | EPH receptor B2 | 0.00802107 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.00786621 |
| ERGIC1 | endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 | 0.00783862 |
| ANKRD10 | ankyrin repeat domain 10 | 0.00771899 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.00771428 |
| AHI1 | Abelson helper integration site 1 | 0.00769926 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.00766937 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.00756388 |
| KLF6 | Kruppel-like factor 6 | 0.00756039 |
| SDC4 | syndecan 4 | 0.00754861 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.00750667 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.00749553 |
| TPTEP2-CSNK1E | TPTEP2-CSNK1E readthrough | 0.00733486 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.0072949 |
| SAFB2 | scaffold attachment factor B2 | 0.00725208 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.00723357 |
| MNT | MAX network transcriptional repressor | 0.00722399 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.00712922 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00712478 |
| ABLIM2 | actin binding LIM protein family, member 2 | 0.00710313 |
| COX6C | cytochrome c oxidase subunit VIc | 0.00709682 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | 0.00709419 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.00707557 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00696425 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00696361 |
| CYTH2 | cytohesin 2 | 0.00693609 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.00686244 |
| PRMT2 | protein arginine methyltransferase 2 | 0.00684667 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.00682125 |
| DOCK5 | dedicator of cytokinesis 5 | 0.00681657 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00681273 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.00678919 |
| CPNE7 | copine VII | 0.00677742 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | 0.00670608 |
| ZNF703 | zinc finger protein 703 | 0.0066889 |
| KIF16B | kinesin family member 16B | 0.0066881 |
| TNRC18 | trinucleotide repeat containing 18 | 0.00668509 |
| RBM6 | RNA binding motif protein 6 | 0.00667527 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0066447 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.00662851 |
| MYO7B | myosin VIIB | 0.00661504 |
| SEPTIN9 | septin 9 | 0.00657927 |
| LRP8 | low density lipoprotein receptor-related protein 8, apolipoprotein e receptor | 0.00657446 |
| SMYD3 | SET and MYND domain containing 3 | 0.00648318 |
| RPLP1 | ribosomal protein, large, P1 | 0.00643526 |
| POF1B | premature ovarian failure, 1B | 0.00641502 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.175038 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0903747 |
| LDHA | lactate dehydrogenase A | -0.0653261 |
| TMSB10 | thymosin beta 10 | -0.0614865 |
| PTMA | prothymosin, alpha | -0.0564531 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0550986 |
| FTL | ferritin, light polypeptide | -0.0548256 |
| RPL35A | ribosomal protein L35a | -0.0518546 |
| GOLGA4 | golgin A4 | -0.0495749 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0477326 |
| FAT1 | FAT atypical cadherin 1 | -0.0452108 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0433567 |
| KRT18 | keratin 18, type I | -0.0399143 |
| RPS6 | ribosomal protein S6 | -0.0396965 |
| ENO1 | enolase 1, (alpha) | -0.0394515 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0381592 |
| POTEF | POTE ankyrin domain family, member F | -0.0365353 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0363039 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0362081 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0360348 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0354031 |
| TXNIP | thioredoxin interacting protein | -0.035085 |
| RPS23 | ribosomal protein S23 | -0.0346268 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0344655 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0331577 |
| NDRG1 | N-myc downstream regulated 1 | -0.0324447 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0317432 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0315729 |
| RPLP2 | ribosomal protein, large, P2 | -0.0309227 |
| TPM4 | tropomyosin 4 | -0.0301168 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0293482 |
| FAM13A | family with sequence similarity 13, member A | -0.029226 |
| RPS19 | ribosomal protein S19 | -0.0287729 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0285786 |
| KIF5B | kinesin family member 5B | -0.0281052 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0277611 |
| RPS8 | ribosomal protein S8 | -0.0272662 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0267499 |
| ITGA6 | integrin, alpha 6 | -0.0263489 |
| RPS13 | ribosomal protein S13 | -0.0263168 |
| RPS25 | ribosomal protein S25 | -0.0258266 |
| MLEC | malectin | -0.0256809 |
| EZR | ezrin | -0.0250769 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0250064 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0247007 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0245454 |
| RPLP0 | ribosomal protein, large, P0 | -0.0242647 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.023978 |
| ACTG1 | actin gamma 1 | -0.0239528 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0239373 |
| CALR | calreticulin | -0.023781 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0237287 |
| ANXA2 | annexin A2 | -0.0235597 |
| SBF2 | SET binding factor 2 | -0.0233306 |
| UBC | ubiquitin C | -0.023216 |
| GOLGB1 | golgin B1 | -0.0231164 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.022791 |
| RPL19 | ribosomal protein L19 | -0.0222724 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0219891 |
| YBX1 | Y box binding protein 1 | -0.0218038 |
| RPS11 | ribosomal protein S11 | -0.0217459 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.021538 |
| RPL31 | ribosomal protein L31 | -0.0210441 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0210281 |
| PARD3 | par-3 family cell polarity regulator | -0.0208434 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0207836 |
| PFN1 | profilin 1 | -0.0207365 |
| MT2A | metallothionein 2A | -0.0206831 |
| RPS12 | ribosomal protein S12 | -0.0205482 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0204068 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0202547 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0200988 |
| RPL11 | ribosomal protein L11 | -0.0199295 |
| RPS16 | ribosomal protein S16 | -0.0195026 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0194961 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0194937 |
| MED13 | mediator complex subunit 13 | -0.0194602 |
| ARF4 | ADP-ribosylation factor 4 | -0.0193086 |
| BBX | bobby sox homolog (Drosophila) | -0.0190521 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0189639 |
| S100P | S100 calcium binding protein P | -0.0189446 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0189417 |
| DSTN | destrin (actin depolymerizing factor) | -0.0189038 |
| KRT8 | keratin 8, type II | -0.0186113 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0185267 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0182973 |
| RPL7 | ribosomal protein L7 | -0.0182021 |
| RPS14 | ribosomal protein S14 | -0.0181703 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0178272 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0176666 |
| RPS27 | ribosomal protein S27 | -0.0176134 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0175199 |
| CLTC | clathrin, heavy chain (Hc) | -0.0173932 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0173054 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.0171379 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0168132 |
| COG5 | component of oligomeric golgi complex 5 | -0.0167913 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0167876 |
| RPL12 | ribosomal protein L12 | -0.0166072 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0165874 |
