| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.158484 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.111284 |
| TMSB10 | thymosin beta 10 | 0.105351 |
| PTMA | prothymosin, alpha | 0.0828517 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0763804 |
| INTS6 | integrator complex subunit 6 | 0.0726094 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0603017 |
| RPLP1 | ribosomal protein, large, P1 | 0.0490437 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0473739 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0458133 |
| RPS24 | ribosomal protein S24 | 0.0456268 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0453614 |
| SEC61G | Sec61 gamma subunit | 0.0441496 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0434123 |
| RPL34 | ribosomal protein L34 | 0.0421069 |
| S100A10 | S100 calcium binding protein A10 | 0.0406032 |
| RPL35A | ribosomal protein L35a | 0.040533 |
| HLA-B | major histocompatibility complex, class I, B | 0.0405177 |
| TRIM56 | tripartite motif containing 56 | 0.0399567 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.03964 |
| SP100 | SP100 nuclear antigen | 0.0395011 |
| RPS25 | ribosomal protein S25 | 0.0379502 |
| EFNA5 | ephrin-A5 | 0.0372054 |
| IER3 | immediate early response 3 | 0.036763 |
| ASPH | aspartate beta-hydroxylase | 0.036219 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0361939 |
| STC1 | stanniocalcin 1 | 0.0358979 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0357957 |
| RNF213 | ring finger protein 213 | 0.0353914 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.034457 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0333419 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0332314 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0329825 |
| B2M | beta-2-microglobulin | 0.0322234 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0321856 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0309889 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0308252 |
| SDC4 | syndecan 4 | 0.0307159 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0303792 |
| FUS | FUS RNA binding protein | 0.030076 |
| RPS8 | ribosomal protein S8 | 0.0296266 |
| RPL37 | ribosomal protein L37 | 0.029186 |
| MYO1E | myosin IE | 0.0290465 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0288231 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0274556 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0269176 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0265116 |
| CMIP | c-Maf inducing protein | 0.0254437 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0252863 |
| RPS29 | ribosomal protein S29 | 0.0252099 |
| ACTG1 | actin gamma 1 | 0.0252077 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | 0.0251893 |
| CDR2 | cerebellar degeneration-related protein 2, 62kDa | 0.0249214 |
| CUX1 | cut-like homeobox 1 | 0.0249202 |
| CTBP2 | C-terminal binding protein 2 | 0.0246135 |
| LAMB3 | laminin, beta 3 | 0.0245392 |
| RPL31 | ribosomal protein L31 | 0.0245123 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | 0.0238973 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0236939 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0234896 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0234835 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0233391 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0231807 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0230346 |
| RPS3 | ribosomal protein S3 | 0.0229447 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0228503 |
| RPL23 | ribosomal protein L23 | 0.0223965 |
| IFI44L | interferon-induced protein 44-like | 0.0223292 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.0221963 |
| TMEM184B | transmembrane protein 184B | 0.0215504 |
| RPL36A | ribosomal protein L36a | 0.0213304 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0212653 |
| RPL8 | ribosomal protein L8 | 0.0212232 |
| SVIL | supervillin | 0.0211449 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.021049 |
| NTSR1 | neurotensin receptor 1 (high affinity) | 0.0209493 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0209306 |
| SMAD3 | SMAD family member 3 | 0.0207718 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.02049 |
| RPS27 | ribosomal protein S27 | 0.0204267 |
| RPS23 | ribosomal protein S23 | 0.0202278 |
| LRRC23 | leucine rich repeat containing 23 | 0.0201538 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0199713 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0199041 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | 0.0196571 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.019634 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0195872 |
| SQSTM1 | sequestosome 1 | 0.0195193 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0194808 |
| MYO1D | myosin ID | 0.019401 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0193053 |
| RPL37A | ribosomal protein L37a | 0.0192776 |
| DISC1 | disrupted in schizophrenia 1 | 0.0192408 |
| CPAMD8 | C3 and PZP-like, alpha-2-macroglobulin domain containing 8 | 0.0192367 |
| S100A9 | S100 calcium binding protein A9 | 0.0192156 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0190338 |
| RPS17 | ribosomal protein S17 | 0.01897 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0189392 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0187503 |
| RAD51B | RAD51 paralog B | 0.01851 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.187342 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.186173 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.16809 |
| CES1 | carboxylesterase 1 | -0.0883045 |
| LDHA | lactate dehydrogenase A | -0.0873103 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0853224 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0818081 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0725642 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0657695 |
| LAMA4 | laminin, alpha 4 | -0.0654034 |
| PKM | pyruvate kinase, muscle | -0.0651311 |
| GRAMD1B | GRAM domain containing 1B | -0.0568218 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0551159 |
| TMEM165 | transmembrane protein 165 | -0.0529686 |
| TES | testin LIM domain protein | -0.0526867 |
| SPAG9 | sperm associated antigen 9 | -0.0488794 |
| NGLY1 | N-glycanase 1 | -0.0487848 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0458646 |
| ARRDC3 | arrestin domain containing 3 | -0.0441412 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0440899 |
| TOP1 | topoisomerase (DNA) I | -0.0428082 |
| PGK1 | phosphoglycerate kinase 1 | -0.041896 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0416372 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0416104 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0412512 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0381609 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0377106 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0375133 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0372817 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0368217 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0367641 |
| CCNL1 | cyclin L1 | -0.0367538 |
| ENO1 | enolase 1, (alpha) | -0.0365961 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0365366 |
| FAM13A | family with sequence similarity 13, member A | -0.0361698 |
| JMJD1C | jumonji domain containing 1C | -0.0347513 |
| MKI67 | marker of proliferation Ki-67 | -0.0344603 |
| OSMR | oncostatin M receptor | -0.0343577 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0342043 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0336638 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0322759 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0317044 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0314522 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0313337 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0312313 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0311772 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0299184 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0299017 |
| CDCP1 | CUB domain containing protein 1 | -0.0298718 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0295156 |
| FTL | ferritin, light polypeptide | -0.0292893 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.029138 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0284929 |
| NCKAP1 | NCK-associated protein 1 | -0.0278765 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0270741 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0268457 |
| EP300 | E1A binding protein p300 | -0.0263075 |
| RNF145 | ring finger protein 145 | -0.026292 |
| NBEAL1 | neurobeachin-like 1 | -0.0262561 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0262131 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0260328 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0260015 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0259841 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0256887 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0256357 |
| ANO6 | anoctamin 6 | -0.0253367 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0251967 |
| ZNF292 | zinc finger protein 292 | -0.0250763 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.025061 |
| TPD52 | tumor protein D52 | -0.0250438 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0250245 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.024681 |
| MYO1B | myosin IB | -0.0246782 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0245472 |
| VMP1 | vacuole membrane protein 1 | -0.0244912 |
| ATP13A3 | ATPase type 13A3 | -0.0244176 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0243893 |
| YEATS2 | YEATS domain containing 2 | -0.0243505 |
| POTEF | POTE ankyrin domain family, member F | -0.0242596 |
| FRYL | FRY-like | -0.0241686 |
| RTN4 | reticulon 4 | -0.0240545 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0239313 |
| OGA | O-GlcNAcase | -0.0238995 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0238908 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0238592 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0237146 |
| ANXA2 | annexin A2 | -0.0233427 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0233029 |
| TFG | TRK-fused gene | -0.0229569 |
| RUNX1 | runt-related transcription factor 1 | -0.02291 |
| HELZ | helicase with zinc finger | -0.0228781 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.02285 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0226552 |
| SUCO | SUN domain containing ossification factor | -0.0226504 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0223889 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0223396 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0220834 |
| EGR1 | early growth response 1 | -0.0220154 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0218739 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0215579 |
