| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0646156 |
| MT1X | metallothionein 1X | 0.0132781 |
| HLA-A | major histocompatibility complex, class I, A | 0.0117027 |
| LAMA5 | laminin, alpha 5 | 0.0115602 |
| RBM25 | RNA binding motif protein 25 | 0.0105771 |
| USP36 | ubiquitin specific peptidase 36 | 0.00944673 |
| BRD4 | bromodomain containing 4 | 0.00917127 |
| MEF2D | myocyte enhancer factor 2D | 0.00824485 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.00823893 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.00783667 |
| AGRN | agrin | 0.00713685 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.00706334 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0069862 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00696211 |
| SF1 | splicing factor 1 | 0.00682748 |
| MT1F | metallothionein 1F | 0.00647818 |
| RUNX1 | runt-related transcription factor 1 | 0.00641685 |
| FBRS | fibrosin | 0.00639551 |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.00633307 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.00597778 |
| MMP24OS | MMP24 opposite strand | 0.00579263 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | 0.0057358 |
| ATF4 | activating transcription factor 4 | 0.00572057 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.00558504 |
| RANBP10 | RAN binding protein 10 | 0.00554766 |
| CLASRP | CLK4-associating serine/arginine rich protein | 0.00553687 |
| PRRC2A | proline-rich coiled-coil 2A | 0.00547628 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.00544275 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.00541569 |
| PGAM4 | phosphoglycerate mutase family member 4 | 0.00526128 |
| INTS1 | integrator complex subunit 1 | 0.00524741 |
| BSDC1 | BSD domain containing 1 | 0.00507444 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0050691 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0050102 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.00482087 |
| CRLF2 | cytokine receptor-like factor 2 | 0.00469598 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.00454055 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.00451834 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0045104 |
| VEGFA | vascular endothelial growth factor A | 0.00450651 |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.00449107 |
| FOSL1 | FOS-like antigen 1 | 0.00440657 |
| BRD2 | bromodomain containing 2 | 0.0043964 |
| STC2 | stanniocalcin 2 | 0.00438729 |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 | 0.00427023 |
| ZBTB7A | zinc finger and BTB domain containing 7A | 0.0042548 |
| SRP54 | signal recognition particle 54kDa | 0.00423782 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.00422769 |
| MNT | MAX network transcriptional repressor | 0.0040932 |
| TSC22D3 | TSC22 domain family, member 3 | 0.00407292 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.00405208 |
| AXL | AXL receptor tyrosine kinase | 0.00402744 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 0.00401586 |
| ZFP36 | ZFP36 ring finger protein | 0.00398576 |
| TOM1 | target of myb1 (chicken) | 0.00398508 |
| SH3GL1 | SH3-domain GRB2-like 1 | 0.00394444 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.00394323 |
| PER1 | period circadian clock 1 | 0.00391345 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.00390865 |
| RHOB | ras homolog family member B | 0.00390785 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.00385851 |
| SRRT | serrate, RNA effector molecule | 0.00382214 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00378973 |
| AMPD2 | adenosine monophosphate deaminase 2 | 0.00378524 |
| EDC4 | enhancer of mRNA decapping 4 | 0.00376369 |
| TRAF4 | TNF receptor-associated factor 4 | 0.00375028 |
| CHERP | calcium homeostasis endoplasmic reticulum protein | 0.00374523 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.00373382 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0037285 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.00371142 |
| CBX4 | chromobox homolog 4 | 0.00369572 |
| PTBP1 | polypyrimidine tract binding protein 1 | 0.00368595 |
| SESN2 | sestrin 2 | 0.00366765 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0036517 |
| PELP1 | proline, glutamate and leucine rich protein 1 | 0.00364456 |
| SREBF1 | sterol regulatory element binding transcription factor 1 | 0.00361215 |
| RCC1 | regulator of chromosome condensation 1 | 0.00360694 |
| PRCC | papillary renal cell carcinoma (translocation-associated) | 0.00360158 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00359236 |
| PCGF2 | polycomb group ring finger 2 | 0.0035731 |
| BAG6 | BCL2-associated athanogene 6 | 0.00355419 |
| INTS11 | integrator complex subunit 11 | 0.00353654 |
| MBD6 | methyl-CpG binding domain protein 6 | 0.0035298 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.00351301 |
| MINK1 | misshapen-like kinase 1 | 0.00350366 |
| CRTC2 | CREB regulated transcription coactivator 2 | 0.00349837 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.00348669 |
| ZBED6 | zinc finger, BED-type containing 6 | 0.00348464 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00346799 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.00344977 |
| BICRA | BRD4 interacting chromatin remodeling complex associated protein | 0.00342926 |
| CNOT3 | CCR4-NOT transcription complex, subunit 3 | 0.00342172 |
| SZRD1 | SUZ RNA binding domain containing 1 | 0.00341713 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.00341463 |
| TMEM259 | transmembrane protein 259 | 0.00339756 |
| YBX3 | Y box binding protein 3 | 0.00337624 |
| CEP170B | centrosomal protein 170B | 0.00335501 |
| TYK2 | tyrosine kinase 2 | 0.00334205 |
| GSK3A | glycogen synthase kinase 3 alpha | 0.00332037 |
| ADRM1 | adhesion regulating molecule 1 | 0.00331303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.180141 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.149367 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.140452 |
| VIM | vimentin | -0.102395 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0946248 |
| GRAMD1B | GRAM domain containing 1B | -0.0792259 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0773741 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0722565 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0686195 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0679131 |
| ASPH | aspartate beta-hydroxylase | -0.0672458 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0622506 |
| TXNRD1 | thioredoxin reductase 1 | -0.06133 |
| ACTG1 | actin gamma 1 | -0.0596968 |
| DST | dystonin | -0.0528255 |
| FTL | ferritin, light polypeptide | -0.0520576 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0516941 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0498864 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0493896 |
| TMSB10 | thymosin beta 10 | -0.0487558 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0485317 |
| LDHA | lactate dehydrogenase A | -0.0473137 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0446481 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0435512 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0431825 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0426776 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0415707 |
| BICC1 | BicC family RNA binding protein 1 | -0.0415527 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0397791 |
| POTEF | POTE ankyrin domain family, member F | -0.0395477 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0390084 |
| UTRN | utrophin | -0.0383537 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0376848 |
| RPL19 | ribosomal protein L19 | -0.0376515 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0375603 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0371217 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.035936 |
| SVIL | supervillin | -0.0359165 |
| RAD51B | RAD51 paralog B | -0.0352447 |
| NEGR1 | neuronal growth regulator 1 | -0.0351331 |
| MCL1 | myeloid cell leukemia 1 | -0.0349783 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0347107 |
| PTMA | prothymosin, alpha | -0.0346846 |
| EFNA5 | ephrin-A5 | -0.034648 |
| FGB | fibrinogen beta chain | -0.0340958 |
| MT2A | metallothionein 2A | -0.0340574 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.033735 |
| TPM4 | tropomyosin 4 | -0.0331157 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0320183 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0318253 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0313655 |
| KYNU | kynureninase | -0.0306697 |
| CMIP | c-Maf inducing protein | -0.0306104 |
| GLIS3 | GLIS family zinc finger 3 | -0.0305762 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0304372 |
| EGR1 | early growth response 1 | -0.0302534 |
| S100A6 | S100 calcium binding protein A6 | -0.0299299 |
| ENO1 | enolase 1, (alpha) | -0.0295651 |
| AHNAK | AHNAK nucleoprotein | -0.0291129 |
| PTK2 | protein tyrosine kinase 2 | -0.0286993 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0286173 |
| APP | amyloid beta (A4) precursor protein | -0.0281934 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0280788 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0277987 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0276955 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0276038 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0275916 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0275844 |
| FMNL2 | formin-like 2 | -0.0275475 |
| ANXA2 | annexin A2 | -0.0268076 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0266265 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0265395 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.026509 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0264782 |
| EGFR | epidermal growth factor receptor | -0.0263907 |
| USP34 | ubiquitin specific peptidase 34 | -0.0262664 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0262347 |
| NRG1 | neuregulin 1 | -0.0261423 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0260448 |
| AHR | aryl hydrocarbon receptor | -0.0259131 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0259071 |
| IGF2 | insulin-like growth factor 2 | -0.0259055 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0258014 |
| WWOX | WW domain containing oxidoreductase | -0.0256625 |
| STC1 | stanniocalcin 1 | -0.0256162 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0254275 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0253676 |
| PKM | pyruvate kinase, muscle | -0.0251558 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0250431 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249028 |
| KIF5B | kinesin family member 5B | -0.0247889 |
| ERBIN | erbb2 interacting protein | -0.0244998 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0240196 |
| MYOF | myoferlin | -0.0239508 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.023891 |
| HDAC9 | histone deacetylase 9 | -0.0238429 |
| S100A10 | S100 calcium binding protein A10 | -0.0238355 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0237218 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0236549 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0236393 |
