| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | 0.132486 |
| PTMA | prothymosin, alpha | 0.115518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0870993 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0856842 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0843268 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0806177 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0760268 |
| RPS8 | ribosomal protein S8 | 0.0731519 |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.067609 |
| HDAC9 | histone deacetylase 9 | 0.0672539 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0653778 |
| RPS16 | ribosomal protein S16 | 0.0632239 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0623802 |
| PHIP | pleckstrin homology domain interacting protein | 0.0617628 |
| COL1A2 | collagen, type I, alpha 2 | 0.0610966 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0599841 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0594597 |
| COL3A1 | collagen, type III, alpha 1 | 0.0579034 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0567687 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0567657 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0566225 |
| SRP54 | signal recognition particle 54kDa | 0.0550692 |
| RPS12 | ribosomal protein S12 | 0.0544226 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0531565 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0528851 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0527771 |
| GNAS | GNAS complex locus | 0.0524113 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0523996 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0515652 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0512901 |
| SNX6 | sorting nexin 6 | 0.0512428 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.050905 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0506052 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0481554 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0472896 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0472357 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.047101 |
| RPL37 | ribosomal protein L37 | 0.0465014 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0462692 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0459602 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0455175 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.044461 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0443766 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0438669 |
| RBM20 | RNA binding motif protein 20 | 0.0433492 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0428908 |
| RPL5 | ribosomal protein L5 | 0.0427319 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0421358 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0411058 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0410983 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0409779 |
| RBM25 | RNA binding motif protein 25 | 0.0405935 |
| MAP4 | microtubule-associated protein 4 | 0.0405169 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0391863 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0384944 |
| JMJD1C | jumonji domain containing 1C | 0.038441 |
| CUX1 | cut-like homeobox 1 | 0.0375025 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0372768 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0371787 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0371422 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0371024 |
| RPL31 | ribosomal protein L31 | 0.0365499 |
| GSE1 | Gse1 coiled-coil protein | 0.0362702 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0362572 |
| OGA | O-GlcNAcase | 0.0361985 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0360872 |
| RPL23 | ribosomal protein L23 | 0.0360449 |
| PHF21A | PHD finger protein 21A | 0.0356872 |
| LPIN2 | lipin 2 | 0.0353731 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0353122 |
| RPL37A | ribosomal protein L37a | 0.034809 |
| ATXN2 | ataxin 2 | 0.0343804 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0342503 |
| RPS21 | ribosomal protein S21 | 0.0341603 |
| RPS13 | ribosomal protein S13 | 0.033631 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0331332 |
| RPLP1 | ribosomal protein, large, P1 | 0.0326674 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0325701 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0324083 |
| CECR2 | cat eye syndrome chromosome region, candidate 2 | 0.0324026 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0321712 |
| RBM39 | RNA binding motif protein 39 | 0.0320287 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.031967 |
| THOC2 | THO complex 2 | 0.0317498 |
| CALR | calreticulin | 0.0316443 |
| FBXO11 | F-box protein 11 | 0.0313409 |
| PUM1 | pumilio RNA-binding family member 1 | 0.031158 |
| GLG1 | golgi glycoprotein 1 | 0.0310015 |
| ANK2 | ankyrin 2, neuronal | 0.0309717 |
| RPS3 | ribosomal protein S3 | 0.0309217 |
| RPL9 | ribosomal protein L9 | 0.0309004 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0307949 |
| APP | amyloid beta (A4) precursor protein | 0.030671 |
| RPS6 | ribosomal protein S6 | 0.030445 |
| CTBP2 | C-terminal binding protein 2 | 0.0302726 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.029878 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0295614 |
| H1-0 | H1.0 linker histone | 0.0295339 |
| SEC62 | SEC62 homolog (S. cerevisiae) | 0.0293404 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.0288711 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0624585 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0553502 |
| POTEF | POTE ankyrin domain family, member F | -0.0506537 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0505341 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0439574 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0434853 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0419413 |
| PEG10 | paternally expressed 10 | -0.0402003 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0398321 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | -0.0359834 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0355124 |
| FOXP2 | forkhead box P2 | -0.0350778 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0348207 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0339755 |
| MKI67 | marker of proliferation Ki-67 | -0.0332332 |
| TPM3 | tropomyosin 3 | -0.0330004 |
| CCN2 | cellular communication network factor 2 | -0.0314003 |
| MPG | N-methylpurine-DNA glycosylase | -0.0309222 |
| ZNF217 | zinc finger protein 217 | -0.0305002 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0294414 |
| EXOC4 | exocyst complex component 4 | -0.0290278 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0289251 |
| FAT1 | FAT atypical cadherin 1 | -0.0287416 |
| CENPF | centromere protein F, 350/400kDa | -0.0284729 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | -0.0283692 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0274414 |
| GPC3 | glypican 3 | -0.0254712 |
| LRRC4C | leucine rich repeat containing 4C | -0.0244751 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0242576 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0231844 |
| CCNA2 | cyclin A2 | -0.0231161 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | -0.0230737 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0223951 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | -0.0219403 |
| THBS1 | thrombospondin 1 | -0.0213834 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | -0.0212844 |
| MLEC | malectin | -0.0210637 |
| MAMDC2 | MAM domain containing 2 | -0.0210122 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0208924 |
| CADM2 | cell adhesion molecule 2 | -0.0208142 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0206425 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | -0.0200116 |
| PCDH9 | protocadherin 9 | -0.0198637 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0198333 |
| DST | dystonin | -0.0198124 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0197095 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.0195021 |
| BSG | basigin (Ok blood group) | -0.0194256 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0193477 |
| PLK2 | polo-like kinase 2 | -0.0191516 |
| SP3 | Sp3 transcription factor | -0.0191418 |
| B2M | beta-2-microglobulin | -0.0191008 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.0190966 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | -0.0190962 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0190124 |
| ZNF608 | zinc finger protein 608 | -0.0189972 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | -0.0188875 |
| FAM91A1 | family with sequence similarity 91, member A1 | -0.0188449 |
| PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | -0.0187362 |
| SPAG9 | sperm associated antigen 9 | -0.0187249 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0186851 |
| RDX | radixin | -0.0186478 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0184611 |
| ITGB8 | integrin, beta 8 | -0.018369 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0182426 |
| SFTPA2 | surfactant protein A2 | -0.0181924 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0181399 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0181282 |
| EFNA5 | ephrin-A5 | -0.0181268 |
| H2AZ2 | H2A.Z variant histone 2 | -0.0180653 |
| ECT2 | epithelial cell transforming 2 | -0.0180132 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit | -0.0177861 |
| MOB1A | MOB kinase activator 1A | -0.0176231 |
| BNC2 | basonuclin 2 | -0.0176224 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0175921 |
| RO60 | Ro60, Y RNA binding protein | -0.0175447 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | -0.0175235 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0174894 |
| CEP170 | centrosomal protein 170kDa | -0.0174632 |
| MED12L | mediator complex subunit 12-like | -0.0172652 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0172398 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0172006 |
| CCNT2 | cyclin T2 | -0.0171826 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0171758 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | -0.017058 |
| SET | SET nuclear proto-oncogene | -0.0170263 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0169529 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0169471 |
| METAP2 | methionyl aminopeptidase 2 | -0.0169005 |
| CACUL1 | CDK2-associated, cullin domain 1 | -0.0168369 |
| FLNA | filamin A, alpha | -0.0167776 |
| FAM171B | family with sequence similarity 171, member B | -0.0167399 |
| NCBP2 | nuclear cap binding protein subunit 2, 20kDa | -0.0167136 |
| BMS1 | BMS1 ribosome biogenesis factor | -0.0166446 |
| KIF4A | kinesin family member 4A | -0.0166132 |
| TMSB4X | thymosin beta 4, X-linked | -0.0166002 |
| FRMD5 | FERM domain containing 5 | -0.0165681 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0165121 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0163332 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | -0.0162862 |
