| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.057355 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0190244 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.017123 |
| MLPH | melanophilin | 0.013659 |
| HLA-A | major histocompatibility complex, class I, A | 0.0134261 |
| RPL9 | ribosomal protein L9 | 0.0127644 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0111369 |
| COL5A1 | collagen, type V, alpha 1 | 0.00996547 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00835674 |
| NABP1 | nucleic acid binding protein 1 | 0.00829772 |
| INTS6 | integrator complex subunit 6 | 0.00780862 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.00772942 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.00767736 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00743089 |
| KYNU | kynureninase | 0.00741716 |
| AGRN | agrin | 0.00734414 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.00693687 |
| C3 | complement component 3 | 0.00689892 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.006839 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00682925 |
| RPL37A | ribosomal protein L37a | 0.00674775 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.00653085 |
| COL27A1 | collagen, type XXVII, alpha 1 | 0.00651939 |
| VEGFA | vascular endothelial growth factor A | 0.00650827 |
| MNT | MAX network transcriptional repressor | 0.0064392 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) | 0.00636359 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00630509 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.00609304 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.00608297 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | 0.00549005 |
| KSR1 | kinase suppressor of ras 1 | 0.00530958 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.00512771 |
| PLXNA3 | plexin A3 | 0.00501367 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.00493587 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.00493373 |
| TOP1 | topoisomerase (DNA) I | 0.00483882 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.00483215 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00480723 |
| INF2 | inverted formin, FH2 and WH2 domain containing | 0.00473091 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.00472889 |
| ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif, 14 | 0.00467425 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.00466317 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.00463523 |
| STX1A | syntaxin 1A (brain) | 0.00459634 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00458058 |
| TRIM25 | tripartite motif containing 25 | 0.00457724 |
| SHISA5 | shisa family member 5 | 0.00451838 |
| KLHL29 | kelch-like family member 29 | 0.00451108 |
| PCBP3 | poly(rC) binding protein 3 | 0.00447418 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00446295 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.00444415 |
| GDF15 | growth differentiation factor 15 | 0.00444262 |
| SH2B3 | SH2B adaptor protein 3 | 0.0044349 |
| SEPTIN9 | septin 9 | 0.00442638 |
| CTSL | cathepsin L | 0.0044045 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0044033 |
| TMEM132A | transmembrane protein 132A | 0.00437581 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0043423 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00429263 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.00426874 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00426643 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | 0.0041591 |
| MNMIP1 | manchette microtubule inner protein 1 | 0.0041528 |
| CUL7 | cullin 7 | 0.00408563 |
| HFE | hemochromatosis | 0.0040778 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00406431 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.00405111 |
| RAB13 | RAB13, member RAS oncogene family | 0.00402242 |
| NTN4 | netrin 4 | 0.00402063 |
| AEBP2 | AE binding protein 2 | 0.00401938 |
| HBEGF | heparin-binding EGF-like growth factor | 0.00400177 |
| TJAP1 | tight junction associated protein 1 (peripheral) | 0.00398035 |
| GDI1 | GDP dissociation inhibitor 1 | 0.00396994 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 | 0.00393407 |
| EGFR | epidermal growth factor receptor | 0.00392474 |
| CPM | carboxypeptidase M | 0.00387321 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.00384578 |
| PMP22 | peripheral myelin protein 22 | 0.00383191 |
| ATG2A | autophagy related 2A | 0.00382762 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.00377635 |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.00376099 |
| NCKIPSD | NCK interacting protein with SH3 domain | 0.00375264 |
| STC2 | stanniocalcin 2 | 0.00374955 |
| ELL | elongation factor RNA polymerase II | 0.00372966 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00372388 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.00370837 |
| MIDN | midnolin | 0.00369676 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.00367559 |
| KXD1 | KxDL motif containing 1 | 0.00366954 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.00366734 |
| WDR59 | WD repeat domain 59 | 0.00365137 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 0.00363584 |
| TRIM55 | tripartite motif containing 55 | 0.0036225 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00358791 |
| HMGA1 | high mobility group AT-hook 1 | 0.00358664 |
| CPNE7 | copine VII | 0.0035647 |
| BRD4 | bromodomain containing 4 | 0.0035624 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.00355486 |
| SMOX | spermine oxidase | 0.00355139 |
| IL32 | interleukin 32 | 0.00354673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.108514 |
| VIM | vimentin | -0.106584 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.103955 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0769054 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.07153 |
| FRMD4A | FERM domain containing 4A | -0.0487738 |
| PGK1 | phosphoglycerate kinase 1 | -0.0421693 |
| PDE10A | phosphodiesterase 10A | -0.0416349 |
| DST | dystonin | -0.0388339 |
| ZNF292 | zinc finger protein 292 | -0.0387042 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0378968 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0367546 |
| VCAN | versican | -0.0335132 |
| CADM1 | cell adhesion molecule 1 | -0.0330916 |
| CD44 | CD44 molecule (Indian blood group) | -0.0329465 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0327176 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0327161 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0326394 |
| ANXA2 | annexin A2 | -0.0321785 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0314385 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0309359 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0296542 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0290716 |
| RPS24 | ribosomal protein S24 | -0.0286868 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0285367 |
| JMJD1C | jumonji domain containing 1C | -0.0284514 |
| IER3 | immediate early response 3 | -0.0277724 |
| B2M | beta-2-microglobulin | -0.0276679 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0276223 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0267389 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0265997 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0263267 |
| GOLGA4 | golgin A4 | -0.0261136 |
| LDHA | lactate dehydrogenase A | -0.0258786 |
| ENO1 | enolase 1, (alpha) | -0.0257446 |
| SFTPA2 | surfactant protein A2 | -0.02563 |
| MYOF | myoferlin | -0.0255684 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0254703 |
| CANX | calnexin | -0.025339 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0253363 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0252115 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0251715 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0245038 |
| NAV2 | neuron navigator 2 | -0.0243038 |
| UBC | ubiquitin C | -0.0240128 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0239874 |
| PTMA | prothymosin, alpha | -0.0237713 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0234019 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0233348 |
| HLA-E | major histocompatibility complex, class I, E | -0.0232983 |
| SPAG9 | sperm associated antigen 9 | -0.0232864 |
| QKI | QKI, KH domain containing, RNA binding | -0.0231892 |
| AHNAK | AHNAK nucleoprotein | -0.0227671 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0223908 |
| HELZ | helicase with zinc finger | -0.0223701 |
| TMSB4X | thymosin beta 4, X-linked | -0.0222948 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0222301 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0221451 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0217812 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0215664 |
| RPLP0 | ribosomal protein, large, P0 | -0.0210666 |
| MKI67 | marker of proliferation Ki-67 | -0.0207227 |
| DIAPH2 | diaphanous-related formin 2 | -0.0205051 |
| MORF4L2 | mortality factor 4 like 2 | -0.02048 |
| CALR | calreticulin | -0.0202813 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0201874 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0201618 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0199962 |
| TUBB | tubulin, beta class I | -0.0197972 |
| ANLN | anillin, actin binding protein | -0.0195823 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0194739 |
| TMEM123 | transmembrane protein 123 | -0.0191818 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0189122 |
| RPLP2 | ribosomal protein, large, P2 | -0.0187789 |
| ACTG1 | actin gamma 1 | -0.018717 |
| MAP4 | microtubule-associated protein 4 | -0.018553 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0185055 |
| ATP13A3 | ATPase type 13A3 | -0.0184919 |
| RPL36A | ribosomal protein L36a | -0.0183377 |
| SBF2 | SET binding factor 2 | -0.0180365 |
| STAG2 | stromal antigen 2 | -0.0179582 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.017834 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0178153 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0178017 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.017782 |
| FNIP1 | folliculin interacting protein 1 | -0.0177748 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0177414 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0177305 |
| SQSTM1 | sequestosome 1 | -0.0176251 |
| RAI14 | retinoic acid induced 14 | -0.0176249 |
| RPS4X | ribosomal protein S4, X-linked | -0.0174964 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0174859 |
| BBX | bobby sox homolog (Drosophila) | -0.017412 |
| TKT | transketolase | -0.0173871 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0173461 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0171058 |
| PLIN2 | perilipin 2 | -0.0170982 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0170137 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0169659 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0169363 |
