| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.0830176 |
| IL6 | interleukin 6 | 0.0531218 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.048376 |
| COL5A1 | collagen, type V, alpha 1 | 0.0444 |
| HLA-B | major histocompatibility complex, class I, B | 0.0397005 |
| CDH13 | cadherin 13 | 0.0392432 |
| HLA-A | major histocompatibility complex, class I, A | 0.033786 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0312878 |
| EGFR | epidermal growth factor receptor | 0.0293308 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0286855 |
| POTEF | POTE ankyrin domain family, member F | 0.025591 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0228862 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0223928 |
| PTGES2 | prostaglandin E synthase 2 | 0.0220434 |
| SDC4 | syndecan 4 | 0.0215096 |
| TPM3 | tropomyosin 3 | 0.0213109 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0211058 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0209533 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0206458 |
| SEC24D | SEC24 family member D | 0.0203986 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0202426 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0188849 |
| RPL28 | ribosomal protein L28 | 0.0188813 |
| C1D | C1D nuclear receptor corepressor | 0.0186685 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0186631 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0185825 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0185189 |
| INTS6 | integrator complex subunit 6 | 0.0184174 |
| LAMB3 | laminin, beta 3 | 0.0183766 |
| L1CAM | L1 cell adhesion molecule | 0.0183505 |
| TAPBP | TAP binding protein (tapasin) | 0.0180067 |
| MAP4 | microtubule-associated protein 4 | 0.0177837 |
| AUTS2 | autism susceptibility candidate 2 | 0.01771 |
| SYNJ2 | synaptojanin 2 | 0.0177056 |
| MYADM | myeloid-associated differentiation marker | 0.0176992 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0175833 |
| INHBA | inhibin, beta A | 0.0175014 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.017387 |
| HLA-C | major histocompatibility complex, class I, C | 0.0172501 |
| UBE3C | ubiquitin protein ligase E3C | 0.0171097 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0170414 |
| MYLK | myosin light chain kinase | 0.0167992 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0163813 |
| FLNA | filamin A, alpha | 0.0163237 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0163115 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0163084 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0162841 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0161074 |
| MSN | moesin | 0.0160465 |
| COL7A1 | collagen, type VII, alpha 1 | 0.016014 |
| ALK | anaplastic lymphoma receptor tyrosine kinase | 0.0159576 |
| AFF3 | AF4/FMR2 family, member 3 | 0.015856 |
| STAG2 | stromal antigen 2 | 0.015856 |
| STXBP1 | syntaxin binding protein 1 | 0.0158546 |
| HDLBP | high density lipoprotein binding protein | 0.0158275 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0156431 |
| PLEC | plectin | 0.0156245 |
| UBAP2 | ubiquitin associated protein 2 | 0.0155578 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0153726 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.015322 |
| MAGT1 | magnesium transporter 1 | 0.0150896 |
| NECTIN3 | nectin cell adhesion molecule 3 | 0.0148981 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0147651 |
| TBCA | tubulin folding cofactor A | 0.0146198 |
| ACLY | ATP citrate lyase | 0.0145889 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0144711 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0142753 |
| SEPTIN9 | septin 9 | 0.0142697 |
| FAM219A | family with sequence similarity 219, member A | 0.0142563 |
| LAMB1 | laminin, beta 1 | 0.0142373 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0141347 |
| MORF4L2 | mortality factor 4 like 2 | 0.0140158 |
| RTN3 | reticulon 3 | 0.0139762 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0139524 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | 0.0138521 |
| MTREX | Mtr4 exosome RNA helicase | 0.0138463 |
| HERPUD2 | HERPUD family member 2 | 0.0138327 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0138131 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0137997 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0137705 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0137287 |
| ANXA6 | annexin A6 | 0.0135846 |
| PMM2 | phosphomannomutase 2 | 0.0133899 |
| SHISA5 | shisa family member 5 | 0.0133835 |
| FNIP1 | folliculin interacting protein 1 | 0.0133787 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0133247 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0132807 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | 0.0132261 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0132234 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.0132036 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.0131991 |
| CDC73 | cell division cycle 73 | 0.0130765 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0130572 |
| COG6 | component of oligomeric golgi complex 6 | 0.0129944 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0128819 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0128289 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.012748 |
| ITM2B | integral membrane protein 2B | 0.0127333 |
| ATM | ATM serine/threonine kinase | 0.0127036 |
| BSG | basigin (Ok blood group) | 0.0126683 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | -0.113808 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0977394 |
| COL1A1 | collagen, type I, alpha 1 | -0.0747304 |
| ENO1 | enolase 1, (alpha) | -0.0676229 |
| MT2A | metallothionein 2A | -0.0626947 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0623166 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0575445 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0520284 |
| FAM13A | family with sequence similarity 13, member A | -0.051459 |
| ARRDC3 | arrestin domain containing 3 | -0.0503812 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.050288 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0500688 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0473589 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0472397 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0445258 |
| COL1A2 | collagen, type I, alpha 2 | -0.0424226 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0424195 |
| MEF2A | myocyte enhancer factor 2A | -0.0421762 |
| CALD1 | caldesmon 1 | -0.040474 |
| H3-3B | H3.3 histone B | -0.0396972 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0388222 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0381218 |
| CALU | calumenin | -0.0376469 |
| CDK6 | cyclin-dependent kinase 6 | -0.0372738 |
| SEPTIN7 | septin 7 | -0.0366043 |
| ANXA2 | annexin A2 | -0.0363245 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0363037 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0361626 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0361474 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0359336 |
| ADM | adrenomedullin | -0.0357694 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0355228 |
| GLIS3 | GLIS family zinc finger 3 | -0.0342426 |
| PGK1 | phosphoglycerate kinase 1 | -0.0335638 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0329197 |
| AHNAK | AHNAK nucleoprotein | -0.0324676 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0323919 |
| MED13L | mediator complex subunit 13-like | -0.0321781 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0319855 |
| FTL | ferritin, light polypeptide | -0.0317878 |
| NDRG1 | N-myc downstream regulated 1 | -0.0317241 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0310946 |
| TPM4 | tropomyosin 4 | -0.0307462 |
| CADM1 | cell adhesion molecule 1 | -0.0306766 |
| PDE10A | phosphodiesterase 10A | -0.0306562 |
| EFNA5 | ephrin-A5 | -0.0301639 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0295313 |
| FN1 | fibronectin 1 | -0.0290884 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0289219 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0284535 |
| ASPH | aspartate beta-hydroxylase | -0.0279002 |
| PTK2 | protein tyrosine kinase 2 | -0.027887 |
| RLF | rearranged L-myc fusion | -0.0277326 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0276812 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0276479 |
| VIM | vimentin | -0.0276095 |
| TXNRD1 | thioredoxin reductase 1 | -0.0275797 |
| WDR26 | WD repeat domain 26 | -0.0272533 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0265424 |
| LOX | lysyl oxidase | -0.0265166 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0260653 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0260429 |
| TPI1 | triosephosphate isomerase 1 | -0.0259759 |
| KAZN | kazrin, periplakin interacting protein | -0.0255922 |
| RTN4 | reticulon 4 | -0.0254105 |
| CD44 | CD44 molecule (Indian blood group) | -0.0253936 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0250209 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0248817 |
| CD99 | CD99 molecule | -0.0247157 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0244967 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0243846 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0243716 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0242766 |
| CANX | calnexin | -0.0242257 |
| GNAS | GNAS complex locus | -0.0239477 |
| LDHA | lactate dehydrogenase A | -0.0238541 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0238174 |
| TXNIP | thioredoxin interacting protein | -0.0235997 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0235987 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0235274 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0230882 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0230017 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0229762 |
| CTTNBP2NL | CTTNBP2 N-terminal like | -0.0227937 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0227859 |
| STC2 | stanniocalcin 2 | -0.0226503 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0226106 |
| OGA | O-GlcNAcase | -0.0225783 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0224501 |
| EMP1 | epithelial membrane protein 1 | -0.0223986 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0223164 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.022034 |
| TNRC6A | trinucleotide repeat containing 6A | -0.0220194 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0219154 |
| GOLGA4 | golgin A4 | -0.0216326 |
| RPL4 | ribosomal protein L4 | -0.0214189 |
| ARF4 | ADP-ribosylation factor 4 | -0.0213806 |
| HIP1 | huntingtin interacting protein 1 | -0.021303 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0208851 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0207728 |
