| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.087782 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0582672 |
| ACTG1 | actin gamma 1 | 0.0549443 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0546588 |
| VIM | vimentin | 0.0538391 |
| SMAD3 | SMAD family member 3 | 0.0533546 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0512969 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0511316 |
| INTS6 | integrator complex subunit 6 | 0.0469468 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0443637 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0441614 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0439357 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0438137 |
| PDE8A | phosphodiesterase 8A | 0.0427902 |
| DST | dystonin | 0.0427256 |
| RIGI | RNA sensor RIG-I | 0.0412314 |
| PGK1 | phosphoglycerate kinase 1 | 0.040479 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0389436 |
| EGR1 | early growth response 1 | 0.0385595 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0380579 |
| RPL26 | ribosomal protein L26 | 0.0376611 |
| RPL34 | ribosomal protein L34 | 0.0371469 |
| RPLP1 | ribosomal protein, large, P1 | 0.0365607 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0365203 |
| TMSB10 | thymosin beta 10 | 0.0360602 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0352814 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0351192 |
| NDRG1 | N-myc downstream regulated 1 | 0.0350797 |
| RPL23 | ribosomal protein L23 | 0.0341264 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.033654 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0331977 |
| HLA-A | major histocompatibility complex, class I, A | 0.0328238 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0327968 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0326229 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0325426 |
| DNAAF9 | dynein axonemal assembly factor 9 | 0.0325349 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0323844 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0320413 |
| RPL37A | ribosomal protein L37a | 0.0316679 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0313133 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0309742 |
| HLA-B | major histocompatibility complex, class I, B | 0.0308165 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0303655 |
| AEBP2 | AE binding protein 2 | 0.0302062 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0299462 |
| RPS8 | ribosomal protein S8 | 0.0299434 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0295876 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0294883 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.029061 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit | 0.0290403 |
| H3-3B | H3.3 histone B | 0.0289526 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0287626 |
| ATM | ATM serine/threonine kinase | 0.0282529 |
| CYTH1 | cytohesin 1 | 0.028251 |
| RBM39 | RNA binding motif protein 39 | 0.0278349 |
| SMYD3 | SET and MYND domain containing 3 | 0.0277459 |
| RPL9 | ribosomal protein L9 | 0.0275334 |
| PKM | pyruvate kinase, muscle | 0.0272169 |
| ANGPTL4 | angiopoietin-like 4 | 0.0272032 |
| RPS12 | ribosomal protein S12 | 0.0269597 |
| MSN | moesin | 0.0268965 |
| SATB2 | SATB homeobox 2 | 0.0266606 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0265623 |
| CAVIN1 | caveolae associated protein 1 | 0.0262893 |
| BRD4 | bromodomain containing 4 | 0.0254984 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0250659 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.024993 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0249824 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.024973 |
| HLA-C | major histocompatibility complex, class I, C | 0.0249183 |
| AREG | amphiregulin | 0.0248327 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0246485 |
| TCERG1 | transcription elongation regulator 1 | 0.0246438 |
| IER3 | immediate early response 3 | 0.0242985 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0242972 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0240834 |
| RBM25 | RNA binding motif protein 25 | 0.023635 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0235965 |
| FTL | ferritin, light polypeptide | 0.0232926 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0228438 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0227349 |
| VEGFA | vascular endothelial growth factor A | 0.022664 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 | 0.0224603 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 0.022343 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0223054 |
| RELA | v-rel avian reticuloendotheliosis viral oncogene homolog A | 0.0221855 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0220953 |
| PTMA | prothymosin, alpha | 0.0220269 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0218564 |
| SAFB2 | scaffold attachment factor B2 | 0.0218076 |
| RPS6 | ribosomal protein S6 | 0.021725 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.021663 |
| MYO9B | myosin IXB | 0.0216432 |
| TJP1 | tight junction protein 1 | 0.0216117 |
| ACTN1 | actinin, alpha 1 | 0.0215838 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0213476 |
| ERBIN | erbb2 interacting protein | 0.0213473 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 0.0212439 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0212346 |
| DSCAM | Down syndrome cell adhesion molecule | 0.02123 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0976976 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0656312 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0637523 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0562985 |
| CLASP1 | cytoplasmic linker associated protein 1 | -0.0446143 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0423663 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0417929 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0417818 |
| KIF5B | kinesin family member 5B | -0.0397514 |
| SEC24A | SEC24 family member A | -0.0383496 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0362915 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0361135 |
| ZNF292 | zinc finger protein 292 | -0.0345701 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0326418 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0322147 |
| AHR | aryl hydrocarbon receptor | -0.0321309 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0318235 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0317724 |
| CCDC91 | coiled-coil domain containing 91 | -0.0311833 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0311762 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.031019 |
| TAOK1 | TAO kinase 1 | -0.0305667 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0304419 |
| PFN1 | profilin 1 | -0.0303041 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0301471 |
| PAPOLA | poly(A) polymerase alpha | -0.0294868 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0294688 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0291987 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | -0.0289672 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0287003 |
| SETX | senataxin | -0.0286719 |
| TXNRD1 | thioredoxin reductase 1 | -0.0286718 |
| ECT2 | epithelial cell transforming 2 | -0.028602 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0283453 |
| KIDINS220 | kinase D-interacting substrate, 220kDa | -0.0282451 |
| GOLT1B | golgi transport 1B | -0.0281992 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.028198 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0281977 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0280926 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0276292 |
| KIAA1328 | KIAA1328 | -0.0275514 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | -0.0275458 |
| ATP11B | ATPase, class VI, type 11B | -0.0275428 |
| MKI67 | marker of proliferation Ki-67 | -0.0275228 |
| RHEB | Ras homolog enriched in brain | -0.0275212 |
| UBQLN1 | ubiquilin 1 | -0.0274747 |
| ATP13A3 | ATPase type 13A3 | -0.0274739 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0274062 |
| NGLY1 | N-glycanase 1 | -0.027297 |
| ANXA5 | annexin A5 | -0.0270462 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0257698 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.0255847 |
| RAB22A | RAB22A, member RAS oncogene family | -0.0255305 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0253888 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.025334 |
| BSG | basigin (Ok blood group) | -0.0253325 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0253091 |
| UTRN | utrophin | -0.0252018 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0249815 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.024854 |
| TBC1D5 | TBC1 domain family, member 5 | -0.024737 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0244852 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0244452 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0244369 |
| PRPF8 | pre-mRNA processing factor 8 | -0.0242348 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0241756 |
| TMEM123 | transmembrane protein 123 | -0.024049 |
| IL6ST | interleukin 6 signal transducer | -0.0240302 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0238935 |
| MORF4L1 | mortality factor 4 like 1 | -0.0237985 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0237929 |
| SPAG9 | sperm associated antigen 9 | -0.0236274 |
| SETD5 | SET domain containing 5 | -0.0236097 |
| SS18 | synovial sarcoma translocation, chromosome 18 | -0.0235093 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | -0.0231029 |
| SEPTIN7 | septin 7 | -0.0230096 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0229853 |
| COG5 | component of oligomeric golgi complex 5 | -0.0229389 |
| CEP170 | centrosomal protein 170kDa | -0.022927 |
| TFG | TRK-fused gene | -0.0227916 |
| BTBD7 | BTB (POZ) domain containing 7 | -0.0226969 |
| ITPRID2 | ITPR interacting domain containing 2 | -0.0226746 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0226713 |
| PRPF4B | pre-mRNA processing factor 4B | -0.0225957 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0225717 |
| RAB1A | RAB1A, member RAS oncogene family | -0.022466 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0223476 |
| DIAPH1 | diaphanous-related formin 1 | -0.0221603 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | -0.0220225 |
| NPAT | nuclear protein, ataxia-telangiectasia locus | -0.0218309 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0215941 |
| RLF | rearranged L-myc fusion | -0.021544 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0215395 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0214596 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0213988 |
| RIN2 | Ras and Rab interactor 2 | -0.0213495 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0212655 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0212613 |
| TES | testin LIM domain protein | -0.0212474 |
| DEK | DEK proto-oncogene | -0.0212382 |
