| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Futibatinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Futibatinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.177817 |
| HMGA2 | high mobility group AT-hook 2 | 0.146839 |
| FN1 | fibronectin 1 | 0.073829 |
| STC2 | stanniocalcin 2 | 0.0682729 |
| EFNA5 | ephrin-A5 | 0.0494322 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0486616 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0471709 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0442157 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0427977 |
| GRB10 | growth factor receptor-bound protein 10 | 0.041073 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0383873 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0380501 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0357276 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0329358 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0315955 |
| TMEM156 | transmembrane protein 156 | 0.0282774 |
| INTS6 | integrator complex subunit 6 | 0.0282566 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0273788 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0254692 |
| GLIS3 | GLIS family zinc finger 3 | 0.0246211 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0244435 |
| RAI14 | retinoic acid induced 14 | 0.023316 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.023083 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0227847 |
| LOXL2 | lysyl oxidase-like 2 | 0.021432 |
| ABR | active BCR-related | 0.0209299 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0205494 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0204457 |
| TENM4 | teneurin transmembrane protein 4 | 0.0198466 |
| MTSS1 | metastasis suppressor 1 | 0.0197419 |
| FLNB | filamin B, beta | 0.0194263 |
| PRKCA | protein kinase C, alpha | 0.0194139 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0193598 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0192658 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0191557 |
| TGFA | transforming growth factor, alpha | 0.0189428 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0186381 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0185619 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0176294 |
| AHRR | aryl-hydrocarbon receptor repressor | 0.0175903 |
| EGFR | epidermal growth factor receptor | 0.0174895 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0172254 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0168938 |
| POU2F2 | POU class 2 homeobox 2 | 0.0168922 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0166314 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0164654 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0164349 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.016189 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0159519 |
| LOX | lysyl oxidase | 0.015678 |
| LRRC23 | leucine rich repeat containing 23 | 0.0153442 |
| GPC6 | glypican 6 | 0.0152114 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0151888 |
| TNS3 | tensin 3 | 0.0150156 |
| RAD51B | RAD51 paralog B | 0.0148504 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.014607 |
| ITGA1 | integrin, alpha 1 | 0.0145866 |
| GPATCH2L | G patch domain containing 2-like | 0.0145849 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0145212 |
| TMEM165 | transmembrane protein 165 | 0.0144565 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.014394 |
| DNAH5 | dynein, axonemal, heavy chain 5 | 0.014326 |
| TNRC6C | trinucleotide repeat containing 6C | 0.0142495 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0139997 |
| VEGFC | vascular endothelial growth factor C | 0.0138683 |
| CADM1 | cell adhesion molecule 1 | 0.0138276 |
| MCL1 | myeloid cell leukemia 1 | 0.0137353 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.01361 |
| FHIT | fragile histidine triad | 0.0135983 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.01359 |
| PLIN2 | perilipin 2 | 0.0132097 |
| ZFYVE28 | zinc finger, FYVE domain containing 28 | 0.0129851 |
| HDAC9 | histone deacetylase 9 | 0.0129823 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0129801 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0129539 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0128428 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.0127868 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0126972 |
| FGF18 | fibroblast growth factor 18 | 0.012613 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0125657 |
| NDRG1 | N-myc downstream regulated 1 | 0.0125472 |
| RANBP17 | RAN binding protein 17 | 0.0123914 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0122741 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0122538 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0121135 |
| CRTAC1 | cartilage acidic protein 1 | 0.0120623 |
| NAV1 | neuron navigator 1 | 0.011967 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0118596 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0118059 |
| MYOF | myoferlin | 0.0117776 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0116228 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0116198 |
| CCDC138 | coiled-coil domain containing 138 | 0.0116108 |
| CTBP2 | C-terminal binding protein 2 | 0.011604 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | 0.0115059 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | 0.0113838 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0112487 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.0111637 |
| POTEF | POTE ankyrin domain family, member F | 0.0111563 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0111557 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.366058 |
| MT2A | metallothionein 2A | -0.132388 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.130649 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.109758 |
| FTL | ferritin, light polypeptide | -0.0752795 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0709854 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0684405 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0649341 |
| CANX | calnexin | -0.0597415 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0576695 |
| AHR | aryl hydrocarbon receptor | -0.0576417 |
| VIM | vimentin | -0.0565563 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0531626 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.053024 |
| RPS6 | ribosomal protein S6 | -0.0523968 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0522914 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0510457 |
| OGA | O-GlcNAcase | -0.0486303 |
| RNF145 | ring finger protein 145 | -0.0485231 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0474883 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0458622 |
| B2M | beta-2-microglobulin | -0.0450945 |
| PTMA | prothymosin, alpha | -0.0445233 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0441923 |
| HLA-B | major histocompatibility complex, class I, B | -0.0426581 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0425057 |
| NEK7 | NIMA-related kinase 7 | -0.0419964 |
| RBM39 | RNA binding motif protein 39 | -0.0415223 |
| TMSB10 | thymosin beta 10 | -0.0408123 |
| RPS19 | ribosomal protein S19 | -0.0399936 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0395622 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0393314 |
| RPLP1 | ribosomal protein, large, P1 | -0.0387808 |
| WDR45B | WD repeat domain 45B | -0.0385945 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0383266 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0382499 |
| RPL26 | ribosomal protein L26 | -0.0373135 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0365592 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0363513 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0361107 |
| SEPTIN7 | septin 7 | -0.0360231 |
| RLF | rearranged L-myc fusion | -0.0360031 |
| RPS12 | ribosomal protein S12 | -0.0356301 |
| TPI1 | triosephosphate isomerase 1 | -0.0351199 |
| CENPF | centromere protein F, 350/400kDa | -0.0350775 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0350458 |
| SUCO | SUN domain containing ossification factor | -0.0346232 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0345816 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0342784 |
| HELZ | helicase with zinc finger | -0.0341026 |
| TFG | TRK-fused gene | -0.0338617 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0337411 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0335897 |
| RACK1 | receptor for activated C kinase 1 | -0.03352 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0335078 |
| TPR | translocated promoter region, nuclear basket protein | -0.0324876 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0322503 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0317633 |
| ZNF292 | zinc finger protein 292 | -0.0316729 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0316697 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0313048 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0311673 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0310671 |
| RPL11 | ribosomal protein L11 | -0.0307885 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0300618 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0300416 |
| PGK1 | phosphoglycerate kinase 1 | -0.0300016 |
| RPS29 | ribosomal protein S29 | -0.0298275 |
| RPS8 | ribosomal protein S8 | -0.0298238 |
| YBX3 | Y box binding protein 3 | -0.0297994 |
| RPS27A | ribosomal protein S27a | -0.0295409 |
| PELO | pelota homolog (Drosophila) | -0.0290983 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0290827 |
| RPL19 | ribosomal protein L19 | -0.0287861 |
| GOLGA4 | golgin A4 | -0.0286208 |
| RHEB | Ras homolog enriched in brain | -0.0283429 |
| S100A10 | S100 calcium binding protein A10 | -0.0280226 |
| RPL30 | ribosomal protein L30 | -0.0279607 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0279257 |
| S100A6 | S100 calcium binding protein A6 | -0.0278433 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0278205 |
| COG5 | component of oligomeric golgi complex 5 | -0.0278077 |
| RPL37A | ribosomal protein L37a | -0.0276236 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0275712 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0275518 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0275416 |
| CLINT1 | clathrin interactor 1 | -0.0275245 |
| YBX1 | Y box binding protein 1 | -0.0274359 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0271746 |
| ETNK1 | ethanolamine kinase 1 | -0.0271527 |
| USP3 | ubiquitin specific peptidase 3 | -0.0270092 |
| RPS20 | ribosomal protein S20 | -0.0269585 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.026841 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0264978 |
| RPL35A | ribosomal protein L35a | -0.0261959 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0261895 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0260897 |
| MATR3 | matrin 3 | -0.0260625 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0260215 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0259184 |
