G protein-coupled acetylcholine receptor signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007213)
External Link http://amigo.geneontology.org/amigo/term/GO_0007213
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Genes

18 genes participating in the G protein-coupled acetylcholine receptor signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AGRN agrin
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRM4 cholinergic receptor, muscarinic 4
CHRM5 cholinergic receptor, muscarinic 5
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GRK2 G protein-coupled receptor kinase 2
HRH3 histamine receptor H3
HRH4 histamine receptor H4
OPRM1 opioid receptor, mu 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RGS10 regulator of G-protein signaling 10
RGS8 regulator of G-protein signaling 8