G1/S transition of mitotic cell cycle Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated. (Gene Ontology, GO_0000082)
External Link http://amigo.geneontology.org/amigo/term/GO_0000082
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Genes

64 genes participating in the G1/S transition of mitotic cell cycle biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ACVR1B activin A receptor, type IB
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BRD4 bromodomain containing 4
CACUL1 CDK2-associated, cullin domain 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CCNE1 cyclin E1
CCNE2 cyclin E2
CDC25A cell division cycle 25A
CDC34 cell division cycle 34
CDC7 cell division cycle 7
CDK14 cyclin-dependent kinase 14
CDK15 cyclin-dependent kinase 15
CDK16 cyclin-dependent kinase 16
CDK17 cyclin-dependent kinase 17
CDK18 cyclin-dependent kinase 18
CDK2 cyclin-dependent kinase 2
CDK3 cyclin-dependent kinase 3
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN3 cyclin-dependent kinase inhibitor 3
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
CUL5 cullin 5
DBF4 DBF4 zinc finger
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
E2F3 E2F transcription factor 3
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
GFI1 growth factor independent 1 transcription repressor
GPR132 G protein-coupled receptor 132
GSPT1 G1 to S phase transition 1
HINFP histone H4 transcription factor
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF11 Kruppel-like factor 11
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NPAT nuclear protein, ataxia-telangiectasia locus
PHF8 PHD finger protein 8
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLK2 polo-like kinase 2
PLK3 polo-like kinase 3
POLE polymerase (DNA directed), epsilon, catalytic subunit
PPP6C protein phosphatase 6, catalytic subunit
RCC1 regulator of chromosome condensation 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SPDYA speedy/RINGO cell cycle regulator family member A
TFDP1 transcription factor Dp-1
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
USP26 ubiquitin specific peptidase 26
USP29 ubiquitin specific peptidase 29
USP37 ubiquitin specific peptidase 37
ZNF324 zinc finger protein 324