G2/M transition of mitotic cell cycle Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex. (Gene Ontology, GO_0000086)
External Link http://amigo.geneontology.org/amigo/term/GO_0000086
Similar Terms
Downloads & Tools

Genes

39 genes participating in the G2/M transition of mitotic cell cycle biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
AURKA aurora kinase A
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BRSK1 BR serine/threonine kinase 1
BRSK2 BR serine/threonine kinase 2
CCDC57 coiled-coil domain containing 57
CCNA2 cyclin A2
CCNB1 cyclin B1
CCNY cyclin Y
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK14 cyclin-dependent kinase 14
CDK2 cyclin-dependent kinase 2
CHEK2 checkpoint kinase 2
DNM2 dynamin 2
ENSA endosulfine alpha
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FOXM1 forkhead box M1
KDM8 lysine (K)-specific demethylase 8
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
LATS1 large tumor suppressor kinase 1
LCMT1 leucine carboxyl methyltransferase 1
MASTL microtubule associated serine/threonine kinase-like
MELK maternal embryonic leucine zipper kinase
NES nestin
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK1 polo-like kinase 1
PLK3 polo-like kinase 3
PPME1 protein phosphatase methylesterase 1
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TPD52L1 tumor protein D52-like 1
UBE2A ubiquitin-conjugating enzyme E2A
USH1C Usher syndrome 1C (autosomal recessive, severe)
WEE1 WEE1 G2 checkpoint kinase