| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | glucose-6-phosphate dehydrogenase|This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2539) |
| External Link | https://ncbi.nlm.nih.gov/gene/2539 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the G6PD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.018664 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0134805 |
| LXN | latexin | 0.0127518 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0123734 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.0122897 |
| PROM1 | prominin 1 | 0.0121488 |
| RGCC | regulator of cell cycle | 0.0121106 |
| TLCD3A | TLC domain containing 3A | 0.0115825 |
| ADM | adrenomedullin | 0.0113524 |
| ASPH | aspartate beta-hydroxylase | 0.011239 |
| CSTA | cystatin A (stefin A) | 0.0110798 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0106688 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0104693 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.0104634 |
| CLCA4 | chloride channel accessory 4 | 0.0104403 |
| NPTX2 | neuronal pentraxin II | 0.0101831 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.010181 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.010073 |
| FCGBP | Fc fragment of IgG binding protein | 0.0100053 |
| ADI1 | acireductone dioxygenase 1 | 0.0099197 |
| ATF3 | activating transcription factor 3 | 0.00988903 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 | 0.0098084 |
| LTF | lactotransferrin | 0.00976764 |
| MT1X | metallothionein 1X | 0.00969892 |
| FN1 | fibronectin 1 | 0.00955008 |
| LYZ | lysozyme | 0.00945434 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.00927498 |
| PSCA | prostate stem cell antigen | 0.00924843 |
| C3 | complement component 3 | 0.00924031 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00923413 |
| LCN2 | lipocalin 2 | 0.00922051 |
| RHOB | ras homolog family member B | 0.00921438 |
| IL1RN | interleukin 1 receptor antagonist | 0.00920877 |
| SIK1 | salt-inducible kinase 1 | 0.00918866 |
| KRT15 | keratin 15, type I | 0.00896958 |
| FABP4 | fatty acid binding protein 4, adipocyte | 0.00890654 |
| KRT13 | keratin 13, type I | 0.00883399 |
| BEX4 | brain expressed, X-linked 4 | 0.00878722 |
| ELANE | elastase, neutrophil expressed | 0.00878635 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.00877929 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.00870615 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) | 0.00866628 |
| CNN3 | calponin 3, acidic | 0.00861926 |
| GPX2 | glutathione peroxidase 2 | 0.00856893 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00856602 |
| A2M | alpha-2-macroglobulin | 0.00853335 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00847682 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.00838655 |
| MT1M | metallothionein 1M | 0.00834961 |
| COQ8A | coenzyme Q8A | 0.00829901 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) | 0.00828561 |
| GPX3 | glutathione peroxidase 3 | 0.00817704 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00811852 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.00802442 |
| ABLIM1 | actin binding LIM protein 1 | 0.00800352 |
| C1S | complement component 1, s subcomponent | 0.00798187 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.0079776 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 0.00788639 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.0078536 |
| PLIN1 | perilipin 1 | 0.00784069 |
| IRS2 | insulin receptor substrate 2 | 0.00781501 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0077402 |
| MMP9 | matrix metallopeptidase 9 | 0.00773846 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | 0.00770742 |
| TSPYL5 | TSPY-like 5 | 0.00769285 |
| G0S2 | G0/G1 switch 2 | 0.00767256 |
| MT1G | metallothionein 1G | 0.00762335 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00761885 |
| NDRG2 | NDRG family member 2 | 0.00758141 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | 0.00754227 |
| FAM13A | family with sequence similarity 13, member A | 0.00752905 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00748076 |
| SPRR3 | small proline-rich protein 3 | 0.0074425 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00742577 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00742252 |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.0074182 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00741181 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00735398 |
| H1-2 | H1.2 linker histone, cluster member | 0.00735277 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | 0.00729567 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00724699 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.00722783 |
| MGP | matrix Gla protein | 0.00722225 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00717772 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.00717581 |
| IL1R2 | interleukin 1 receptor, type II | 0.00713629 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.00711485 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00710265 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | 0.00709901 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00708276 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00706426 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00705859 |
| POU2AF1 | POU class 2 associating factor 1 | 0.00701865 |
| DEFB1 | defensin, beta 1 | 0.0070175 |
| AHSG | alpha-2-HS-glycoprotein | 0.00699626 |
| BTG2 | BTG family, member 2 | 0.00698827 |
| MXRA5 | matrix-remodelling associated 5 | 0.0069824 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00696262 |
| MT1F | metallothionein 1F | 0.00691989 |
| EMP1 | epithelial membrane protein 1 | 0.00686164 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.00684942 |
| NMB | neuromedin B | 0.00681657 |
| MT1E | metallothionein 1E | 0.00672652 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00671826 |
| S100A9 | S100 calcium binding protein A9 | 0.00669437 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.00669089 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00667756 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 | 0.00667225 |
| MCAM | melanoma cell adhesion molecule | 0.00663023 |
| CA2 | carbonic anhydrase II | 0.00662916 |
| PCNA | proliferating cell nuclear antigen | 0.00661003 |
| GLUL | glutamate-ammonia ligase | 0.00660069 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.00659883 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.00658504 |
| DCHS1 | dachsous cadherin-related 1 | 0.00658343 |
| MUC4 | mucin 4, cell surface associated | 0.00657253 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | 0.00656087 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.00655548 |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 | 0.00655179 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.00654885 |
| PCGF2 | polycomb group ring finger 2 | 0.00653838 |
| RETREG1 | reticulophagy regulator 1 | 0.00651472 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | 0.00651116 |
| HHEX | hematopoietically expressed homeobox | 0.00650788 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | 0.00649356 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.00644661 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00640294 |
| NID2 | nidogen 2 (osteonidogen) | 0.00638192 |
| JAG1 | jagged 1 | 0.00633805 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.0063199 |
| CFB | complement factor B | 0.00627146 |
| SCPEP1 | serine carboxypeptidase 1 | 0.00626432 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.0062586 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 | 0.00625567 |
| CAB39 | calcium binding protein 39 | 0.0062255 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00621485 |
| AQP9 | aquaporin 9 | 0.00621217 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C | 0.00621213 |
| PLTP | phospholipid transfer protein | 0.00620922 |
| CP | ceruloplasmin (ferroxidase) | 0.00620726 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0061862 |
| CHPT1 | choline phosphotransferase 1 | 0.00617455 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | 0.00613407 |
| S100P | S100 calcium binding protein P | 0.00611584 |
| EHBP1 | EH domain binding protein 1 | 0.00611051 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00610392 |
| MSMB | microseminoprotein, beta- | 0.0060584 |
| H1-0 | H1.0 linker histone | 0.00605651 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | 0.0060565 |
| MB | myoglobin | 0.00604567 |
| CTSH | cathepsin H | 0.00603043 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | 0.00602873 |
| PTK2 | protein tyrosine kinase 2 | 0.00599276 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | 0.00598423 |
| ASPN | asporin | 0.00598241 |
| HLA-B | major histocompatibility complex, class I, B | 0.00597675 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0059638 |
| C5AR1 | complement component 5a receptor 1 | 0.00593449 |
| C8ORF4 | chromosome 8 open reading frame 4 | 0.00592333 |
| KDSR | 3-ketodihydrosphingosine reductase | 0.00589833 |
| TTC9 | tetratricopeptide repeat domain 9 | 0.00586247 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.0058602 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00585466 |
| MYO1B | myosin IB | 0.00580191 |
| MT1H | metallothionein 1H | 0.00580114 |
| SELL | selectin L | 0.00580036 |
| ENOPH1 | enolase-phosphatase 1 | 0.00577832 |
| NCAM1 | neural cell adhesion molecule 1 | 0.00575833 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00575794 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00575585 |
| S100A8 | S100 calcium binding protein A8 | 0.00574438 |
| GSR | glutathione reductase | 0.00571472 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | 0.00570824 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.00569782 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | 0.00568757 |
| TSC22D1 | TSC22 domain family, member 1 | 0.00568301 |
| CCDC81 | coiled-coil domain containing 81 | 0.00568072 |
| CFH | complement factor H | 0.00568022 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00566126 |
| COL15A1 | collagen, type XV, alpha 1 | 0.00564683 |
| CRNN | cornulin | 0.00563327 |
| FGB | fibrinogen beta chain | 0.0056053 |
| H1-10 | H1.10 linker histone | 0.00559163 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | 0.00558775 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00557852 |
| SAA4 | serum amyloid A4, constitutive | 0.00556516 |
| WWOX | WW domain containing oxidoreductase | 0.00555601 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.00553632 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.00553289 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.00549811 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00548108 |
| CALR | calreticulin | 0.00545701 |
| FERMT1 | fermitin family member 1 | 0.00543813 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | 0.00542465 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | 0.00542111 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 0.00541812 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00541395 |
| APOA2 | apolipoprotein A-II | 0.00541067 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.00541 |
| CLC | Charcot-Leyden crystal galectin | 0.00540334 |
| RBPMS | RNA binding protein with multiple splicing | 0.00540274 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.00540115 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0054003 |
| RAB13 | RAB13, member RAS oncogene family | 0.00539929 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00539815 |
| RAP1GAP | RAP1 GTPase activating protein | 0.00537989 |
| POSTN | periostin, osteoblast specific factor | 0.00535979 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 0.00535885 |
| VRK2 | vaccinia related kinase 2 | 0.00535258 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00535169 |
| MPO | myeloperoxidase | 0.00534977 |
| PALMD | palmdelphin | 0.00533229 |
| AZU1 | azurocidin 1 | 0.00532727 |
| HOXB2 | homeobox B2 | 0.00532643 |
| GPX1 | glutathione peroxidase 1 | 0.00532114 |
| BGN | biglycan | 0.00531746 |
| TMEM45A | transmembrane protein 45A | 0.00531273 |
| DCT | dopachrome tautomerase | 0.00529641 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00529188 |
| GRAMD2B | GRAM domain containing 2B | 0.00528523 |
| TRIM24 | tripartite motif containing 24 | 0.00528073 |
| WFDC2 | WAP four-disulfide core domain 2 | 0.0052638 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00525953 |
| CTSE | cathepsin E | 0.00525896 |
| FZD4 | frizzled class receptor 4 | 0.00524152 |
| PEG3 | paternally expressed 3 | 0.00521383 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.00520887 |
| MPZL2 | myelin protein zero-like 2 | 0.0052083 |
| TOB1 | transducer of ERBB2, 1 | 0.00520464 |
| EPAS1 | endothelial PAS domain protein 1 | 0.00520213 |
| S100A14 | S100 calcium binding protein A14 | 0.00517986 |
| PIR | pirin (iron-binding nuclear protein) | 0.00517862 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) | 0.00516929 |
| KRT19 | keratin 19, type I | 0.00516376 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | 0.00516239 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 | 0.00510982 |
| OPHN1 | oligophrenin 1 | 0.0051089 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00510637 |
| LARP4 | La ribonucleoprotein domain family, member 4 | 0.00510007 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0050943 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.00509365 |
| FMO3 | flavin containing monooxygenase 3 | 0.00508666 |
| AEBP1 | AE binding protein 1 | 0.00508381 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00507549 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00506274 |
| CLTB | clathrin, light chain B | 0.00505762 |
| ARG2 | arginase 2 | 0.00504918 |
| MGLL | monoglyceride lipase | 0.00503695 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 | 0.00502488 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00502307 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.0124084 |
| RB1 | retinoblastoma 1 | -0.0119588 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.0104789 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | -0.00979515 |
| CANT1 | calcium activated nucleotidase 1 | -0.00972423 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.00970757 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | -0.00959846 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00942139 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00910917 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00909472 |
| DACH1 | dachshund family transcription factor 1 | -0.00908382 |
| PLAT | plasminogen activator, tissue | -0.00895097 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00895034 |
| AUTS2 | autism susceptibility candidate 2 | -0.0089001 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00882765 |
| AOC1 | amine oxidase, copper containing 1 | -0.00881167 |
| GLS | glutaminase | -0.00868642 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.00861899 |
| TMEM176B | transmembrane protein 176B | -0.00859869 |
| CTSZ | cathepsin Z | -0.00838339 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00828878 |
| AGR2 | anterior gradient 2 | -0.00821907 |
| CALB1 | calbindin 1, 28kDa | -0.00821725 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00821506 |
| CTSW | cathepsin W | -0.0080898 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.00782004 |
| CLIC3 | chloride intracellular channel 3 | -0.00764262 |
| CERK | ceramide kinase | -0.00753309 |
| TMEM176A | transmembrane protein 176A | -0.00747141 |
| XIC | X chromosome inactivation center | -0.00738353 |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 | -0.00727642 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.0072555 |
| NEFH | neurofilament, heavy polypeptide | -0.00724495 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | -0.00712428 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.0070571 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00703491 |
| CYBRD1 | cytochrome b reductase 1 | -0.00703367 |
| PRF1 | perforin 1 (pore forming protein) | -0.00701019 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | -0.00697597 |
| VEGFA | vascular endothelial growth factor A | -0.00693582 |
| NKG7 | natural killer cell granule protein 7 | -0.00681728 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00681581 |
| CD8A | CD8a molecule | -0.0067497 |
| NPR3 | natriuretic peptide receptor 3 | -0.00672916 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00670875 |
| DIO2 | deiodinase, iodothyronine, type II | -0.00669885 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.00667334 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 | -0.00666751 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | -0.00662067 |
| ANK2 | ankyrin 2, neuronal | -0.00661303 |
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | -0.00660171 |
| IER5 | immediate early response 5 | -0.00657133 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00655023 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00653418 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.0065341 |
| PDZK1 | PDZ domain containing 1 | -0.00650916 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00650205 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | -0.00638366 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | -0.00637525 |
| GLO1 | glyoxalase I | -0.00637488 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 | -0.0063424 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | -0.00633245 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00632907 |
| ALDOB | aldolase B, fructose-bisphosphate | -0.00631246 |
| GPR88 | G protein-coupled receptor 88 | -0.00631089 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.00627104 |
| MEA1 | male-enhanced antigen 1 | -0.00624212 |
| ZNF589 | zinc finger protein 589 | -0.00621737 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00620892 |
| AKR7A3 | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | -0.00620107 |
| KLF10 | Kruppel-like factor 10 | -0.00619455 |
| TARP | TCR gamma alternate reading frame protein | -0.00618577 |
| NDRG1 | N-myc downstream regulated 1 | -0.00617287 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.00615804 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.00615427 |
| PTN | pleiotrophin | -0.00613357 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | -0.0060697 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00601468 |
| PDGFC | platelet derived growth factor C | -0.00601365 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00600956 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00600909 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00598814 |
| EDNRA | endothelin receptor type A | -0.00596477 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00594631 |
| NTS | neurotensin | -0.00591571 |
| TLE4 | transducin-like enhancer of split 4 | -0.00588695 |
| HOPX | HOP homeobox | -0.00585804 |
| PLSCR3 | phospholipid scramblase 3 | -0.00585737 |
| FZD2 | frizzled class receptor 2 | -0.00582426 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0058093 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | -0.00576731 |
| POGLUT2 | protein O-glucosyltransferase 2 | -0.00574532 |
| FADD | Fas (TNFRSF6)-associated via death domain | -0.00574156 |
| HPCAL1 | hippocalcin-like 1 | -0.00572956 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | -0.00572405 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.00571835 |
| GNLY | granulysin | -0.00571418 |
| PENK | proenkephalin | -0.00571269 |
| SMAD6 | SMAD family member 6 | -0.00571112 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00567641 |
| ITM2B | integral membrane protein 2B | -0.00566392 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00565899 |
| EFNB2 | ephrin-B2 | -0.00563665 |
| IL7R | interleukin 7 receptor | -0.00559902 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00559194 |
| CISH | cytokine inducible SH2-containing protein | -0.00555645 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 | -0.00555642 |
| RGS4 | regulator of G-protein signaling 4 | -0.00555296 |
| TXNIP | thioredoxin interacting protein | -0.00554264 |
| CLIC1 | chloride intracellular channel 1 | -0.00551956 |
| GPM6A | glycoprotein M6A | -0.00551698 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.00551137 |
| ENO1 | enolase 1, (alpha) | -0.00550085 |
| MLPH | melanophilin | -0.00547146 |
| LRRC17 | leucine rich repeat containing 17 | -0.0054635 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00546227 |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | -0.00545147 |
| NELL1 | NEL-like 1 (chicken) | -0.00543948 |
| TPBG | trophoblast glycoprotein | -0.00543623 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00543222 |
| JADE2 | jade family PHD finger 2 | -0.0053901 |
| PKP4 | plakophilin 4 | -0.00535707 |
| CUTA | cutA divalent cation tolerance homolog (E. coli) | -0.00533973 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -0.00532434 |
| ECI2 | enoyl-CoA delta isomerase 2 | -0.00528944 |
| PLXNA1 | plexin A1 | -0.00526611 |
| BATF | basic leucine zipper transcription factor, ATF-like | -0.00526383 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) | -0.00526152 |
| ILF2 | interleukin enhancer binding factor 2 | -0.00525512 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.00525099 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00523922 |
| SPANXD | SPANX family, member D | -0.00520289 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | -0.00520232 |
| MAGEA1 | melanoma antigen family A1 | -0.0051941 |
| DUSP7 | dual specificity phosphatase 7 | -0.00519046 |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | -0.00518871 |
| MYRF | myelin regulatory factor | -0.00518122 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -0.00516405 |
| DSP | desmoplakin | -0.00515684 |
| IL10RA | interleukin 10 receptor, alpha | -0.00515429 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.00514973 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00514176 |
| TOR1A | torsin family 1, member A (torsin A) | -0.00511868 |
| HOMER1 | homer scaffolding protein 1 | -0.00511352 |
| RDH14 | retinol dehydrogenase 14 (all-trans/9-cis/11-cis) | -0.00508137 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | -0.00507856 |
| MYLK | myosin light chain kinase | -0.00505606 |
| HDAC1 | histone deacetylase 1 | -0.0050521 |
| PALLD | palladin, cytoskeletal associated protein | -0.00501776 |
| CDK17 | cyclin-dependent kinase 17 | -0.00500078 |
| FOXF1 | forkhead box F1 | -0.00499799 |
| CLDND1 | claudin domain containing 1 | -0.00499657 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I | -0.00498982 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | -0.00497225 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00496581 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.00496526 |
| FBN2 | fibrillin 2 | -0.00495929 |
| BCAT2 | branched chain amino-acid transaminase 2, mitochondrial | -0.00494697 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00494397 |
| HAS2 | hyaluronan synthase 2 | -0.00491586 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00491416 |
| NENF | neudesin neurotrophic factor | -0.00490775 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00490298 |
| EFHD1 | EF-hand domain family, member D1 | -0.00488628 |
| TENM3 | teneurin transmembrane protein 3 | -0.00488627 |
| PEX6 | peroxisomal biogenesis factor 6 | -0.00488243 |
| ERH | enhancer of rudimentary homolog (Drosophila) | -0.00487801 |
| DOCK10 | dedicator of cytokinesis 10 | -0.00487506 |
| NDNF | neuron-derived neurotrophic factor | -0.00486473 |
| MAGEA3 | melanoma antigen family A3 | -0.00486448 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00486299 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | -0.00485926 |
| THY1 | Thy-1 cell surface antigen | -0.00483628 |
| MEIS2 | Meis homeobox 2 | -0.0048237 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0048033 |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | -0.00480214 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.00480129 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -0.00477685 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00476985 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.00476558 |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | -0.00476211 |
| IL2RG | interleukin 2 receptor, gamma | -0.00475952 |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | -0.00473884 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00473551 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 | -0.0047173 |
| EDF1 | endothelial differentiation-related factor 1 | -0.00471224 |
| ADCY3 | adenylate cyclase 3 | -0.00470402 |
| ATP5MF | ATP synthase membrane subunit f | -0.00469846 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.00468043 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | -0.00467294 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.00466088 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00465599 |
| MRPL24 | mitochondrial ribosomal protein L24 | -0.00465483 |
| RPA3 | replication protein A3, 14kDa | -0.00464747 |
| ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | -0.00464517 |
| CTSC | cathepsin C | -0.00464147 |
| HAL | histidine ammonia-lyase | -0.0046403 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00463927 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00463274 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | -0.00462689 |
| IFNG | interferon, gamma | -0.00462546 |
| SFN | stratifin | -0.00461981 |
| KRT14 | keratin 14, type I | -0.00461215 |
| CYCS | cytochrome c, somatic | -0.00460964 |
| ADCY9 | adenylate cyclase 9 | -0.00460913 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00460501 |
| HIST1H2BK | histone cluster 1, H2bk | -0.00460213 |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | -0.00459921 |
| ADAR | adenosine deaminase, RNA-specific | -0.00459393 |
| HINT1 | histidine triad nucleotide binding protein 1 | -0.00457959 |
| ANXA5 | annexin A5 | -0.00457255 |
| SNX11 | sorting nexin 11 | -0.00456312 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.00455168 |
| LPXN | leupaxin | -0.00454893 |
| CST7 | cystatin F (leukocystatin) | -0.00453431 |
| STAT4 | signal transducer and activator of transcription 4 | -0.00452122 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) | -0.0045198 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | -0.00451659 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | -0.0045137 |
| SACS | sacsin molecular chaperone | -0.00450759 |
| CCNB1 | cyclin B1 | -0.00450156 |
| PRDX2 | peroxiredoxin 2 | -0.00449368 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00448838 |
| LDOC1 | leucine zipper, down-regulated in cancer 1 | -0.00448627 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | -0.00448233 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | -0.00447762 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00446549 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0044652 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | -0.00444988 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | -0.00442555 |
| TMEM106C | transmembrane protein 106C | -0.00440918 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | -0.00440375 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) | -0.00437872 |
| ODC1 | ornithine decarboxylase 1 | -0.00437257 |
| ATP8A1 | ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 | -0.00436766 |
| SLC35F2 | solute carrier family 35, member F2 | -0.00436722 |
| ESR1 | estrogen receptor 1 | -0.0043664 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.00434791 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.00432402 |
| IL2RB | interleukin 2 receptor, beta | -0.00432221 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00431976 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | -0.00431835 |
| ITGB4 | integrin, beta 4 | -0.00431786 |
| CHTOP | chromatin target of PRMT1 | -0.00431334 |
| F2R | coagulation factor II (thrombin) receptor | -0.00431216 |
| CLDN3 | claudin 3 | -0.00430605 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.00429798 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) | -0.00429468 |
| RYBP | RING1 and YY1 binding protein | -0.00428131 |
