G6PD Gene Set

Dataset NURSA Protein-Protein Interactions
Category proteomics
Type interacting protein
Description glucose-6-phosphate dehydrogenase|This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2539)
External Link http://www.ncbi.nlm.nih.gov/gene/2539
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Genes

5 interacting proteins for G6PD from the NURSA Protein-Protein Interactions dataset.

Symbol Name Standardized Value
BPIFB6 BPI fold containing family B, member 6 0.15278
GHDC GH3 domain containing 0.15278
CEP44 centrosomal protein 44kDa 0.15278
NUP50 nucleoporin 50kDa 0.15278
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2 0.15278