GABAPENTIN ENACARBIL Gene Set

Dataset DGIdb Drug Targets 2026
Category physical interactions
Type drug
Description A carbamate ester that is the N-[1-(isobutyryloxy)ethoxy]carbonyl derivative of [1-(aminomethyl)cyclohexyl]acetic acid. The prodrug for gabapentin, used for treatment of neuropathic pain and restless legs syndrome. (Chemical Entities of Biological Interest Ontology, CHEBI_68840)
External Link https://dgidb.org/results?searchType=drug&searchTerms=GABAPENTIN ENACARBIL
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Genes

27 interacting proteins for the GABAPENTIN ENACARBIL drug from theDGIdb Drug Targets 2026 dataset.

Symbol Name Standardized Value
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 1.96044
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.261393
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.217827
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 0.217827
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 0.217827
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 0.217827
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.217827
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 0.217827
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.196044
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.196044
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 0.196044
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.178222
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.150803
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.150803
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.150803
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.140032
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.130696
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.130696
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 0.122528
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.103181
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.0676015
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.0612639
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.0455917
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.0426183
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.0426183
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.0350079
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.0343938