| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gamma-aminobutyric acid (GABA) B receptor, 2|The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010] (NCBI Entrez Gene Database, 9568) |
| External Link | https://ncbi.nlm.nih.gov/gene/9568 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the GABBR2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0156349 |
| SNX7 | sorting nexin 7 | 0.0148063 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | 0.0145794 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.0120521 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0109805 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 0.0108445 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 0.0106583 |
| NNMT | nicotinamide N-methyltransferase | 0.0104728 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.0101796 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.010123 |
| TCTA | T-cell leukemia translocation altered | 0.0100013 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00921008 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 | 0.00914186 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | 0.00906654 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00835515 |
| TYRP1 | tyrosinase-related protein 1 | 0.00829148 |
| RET | ret proto-oncogene | 0.00804618 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00792128 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | 0.00780379 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.0077957 |
| IRX5 | iroquois homeobox 5 | 0.00765416 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 | 0.0076034 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00757432 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00757431 |
| STK10 | serine/threonine kinase 10 | 0.00753398 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.00750222 |
| CYB5R2 | cytochrome b5 reductase 2 | 0.00748356 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00746296 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.00743219 |
| MARCKSL1 | MARCKS-like 1 | 0.00739178 |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial | 0.00735876 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | 0.00734616 |
| VNN1 | vanin 1 | 0.00722761 |
| SPAG16 | sperm associated antigen 16 | 0.00721392 |
| KLK7 | kallikrein-related peptidase 7 | 0.0072078 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0071949 |
| LAPTM4B | lysosomal protein transmembrane 4 beta | 0.00719366 |
| COL3A1 | collagen, type III, alpha 1 | 0.0070712 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.0070579 |
| CALML3 | calmodulin-like 3 | 0.00699917 |
| RETREG1 | reticulophagy regulator 1 | 0.00691613 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00690882 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0068882 |
| PROM1 | prominin 1 | 0.00687724 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00681615 |
| DLK1 | delta-like 1 homolog (Drosophila) | 0.00680414 |
| ZNF395 | zinc finger protein 395 | 0.00679427 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00675812 |
| ZNF160 | zinc finger protein 160 | 0.00675727 |
| CALML5 | calmodulin-like 5 | 0.00669768 |
| ECM1 | extracellular matrix protein 1 | 0.00668734 |
| CA2 | carbonic anhydrase II | 0.00666566 |
| PDZK1 | PDZ domain containing 1 | 0.00660533 |
| CPB1 | carboxypeptidase B1 (tissue) | 0.00657467 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00657038 |
| S100A7 | S100 calcium binding protein A7 | 0.0065697 |
| CD200 | CD200 molecule | 0.00655144 |
| NEBL | nebulette | 0.00652961 |
| FABP7 | fatty acid binding protein 7, brain | 0.00643885 |
| RGS1 | regulator of G-protein signaling 1 | 0.00643312 |
| LOR | loricrin | 0.00642693 |
| KIAA0125 | KIAA0125 | 0.00642081 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0064176 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.00640955 |
| COL1A2 | collagen, type I, alpha 2 | 0.00640387 |
| EGR2 | early growth response 2 | 0.00640308 |
| IL6ST | interleukin 6 signal transducer | 0.006402 |
| MGLL | monoglyceride lipase | 0.00637899 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 0.00637628 |
| PXDN | peroxidasin | 0.00637602 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00634057 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00630616 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.00627675 |
| ATP10B | ATPase, class V, type 10B | 0.00625428 |
| HAL | histidine ammonia-lyase | 0.00612032 |
| SDC2 | syndecan 2 | 0.00608675 |
| TPBG | trophoblast glycoprotein | 0.00608149 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00608087 |
| FTO | fat mass and obesity associated | 0.00603639 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00602568 |
| EMP2 | epithelial membrane protein 2 | 0.00601151 |
| QPCT | glutaminyl-peptide cyclotransferase | 0.006 |
| EDNRB | endothelin receptor type B | 0.00599169 |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.005929 |
| FKBP10 | FK506 binding protein 10, 65 kDa | 0.00586875 |
| KRT2 | keratin 2, type II | 0.00584181 |
| LOXL2 | lysyl oxidase-like 2 | 0.0058172 |
| GBA3 | glucosidase, beta, acid 3 (gene/pseudogene) | 0.00580313 |
| ZNF587 | zinc finger protein 587 | 0.00579675 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.00579636 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00577387 |
| PRKD3 | protein kinase D3 | 0.00577305 |
| FRZB | frizzled-related protein | 0.00577284 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00575403 |
| FAR2 | fatty acyl CoA reductase 2 | 0.00575143 |
| AK4 | adenylate kinase 4 | 0.00574622 |
| HOXC6 | homeobox C6 | 0.00572833 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | 0.00572078 |
| DSG1 | desmoglein 1 | 0.00570263 |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.00570077 |
| ASPA | aspartoacylase | 0.0056934 |
| TWIST1 | twist family bHLH transcription factor 1 | 0.00567391 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00567203 |
| ARG1 | arginase 1 | 0.00565795 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | 0.00565451 |
| BCL2 | B-cell CLL/lymphoma 2 | 0.00564501 |
| IGFBP4 | insulin-like growth factor binding protein 4 | 0.00563722 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00561223 |
| KAZN | kazrin, periplakin interacting protein | 0.00560243 |
| GPM6B | glycoprotein M6B | 0.00559402 |
| MSN | moesin | 0.00556076 |
| FLT3 | fms-related tyrosine kinase 3 | 0.00554879 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 0.00553495 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | 0.00552974 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | 0.00552712 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | 0.00550875 |
| FCGBP | Fc fragment of IgG binding protein | 0.00549634 |
| GATA6 | GATA binding protein 6 | 0.00548491 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 | 0.00548082 |
| CD300A | CD300a molecule | 0.00546348 |
| MFAP2 | microfibrillar-associated protein 2 | 0.00545261 |
| TSPAN3 | tetraspanin 3 | 0.00544915 |
| BICC1 | BicC family RNA binding protein 1 | 0.00544542 |
| KLK6 | kallikrein-related peptidase 6 | 0.00541215 |
| BCAS1 | breast carcinoma amplified sequence 1 | 0.00538348 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | 0.00537192 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.0053688 |
| FBXO2 | F-box protein 2 | 0.00535101 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | 0.00534902 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.00534358 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 | 0.00533744 |
| FBXW12 | F-box and WD repeat domain containing 12 | 0.00532597 |
| FMO1 | flavin containing monooxygenase 1 | 0.00529889 |
| HPCAL1 | hippocalcin-like 1 | 0.00529748 |
| ILK | integrin-linked kinase | 0.00529603 |
| CLCA1 | chloride channel accessory 1 | 0.00527493 |
| PRR5L | proline rich 5 like | 0.00526989 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 | 0.00526809 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00524454 |
| COPS7A | COP9 signalosome subunit 7A | 0.00524031 |
| ANXA6 | annexin A6 | 0.00523969 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00520489 |
| ADCY3 | adenylate cyclase 3 | 0.00519822 |
| MMP3 | matrix metallopeptidase 3 | 0.00519602 |
| KLK5 | kallikrein-related peptidase 5 | 0.00519252 |
| POGLUT2 | protein O-glucosyltransferase 2 | 0.00519174 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | 0.00519151 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00515488 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.00515369 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.00514422 |
| TPI1 | triosephosphate isomerase 1 | 0.005126 |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.00511992 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.00511035 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 0.00511028 |
| ACKR3 | atypical chemokine receptor 3 | 0.00510944 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.00509337 |
| PGAM1 | phosphoglycerate mutase 1 (brain) | 0.00509294 |
| ZNF611 | zinc finger protein 611 | 0.00508918 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00506722 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00505933 |
| ASB13 | ankyrin repeat and SOCS box containing 13 | 0.00505796 |
| RPA3 | replication protein A3, 14kDa | 0.0050153 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0050044 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | 0.00500292 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00500115 |
| TLR4 | toll-like receptor 4 | 0.00499196 |
| ALDOC | aldolase C, fructose-bisphosphate | 0.00499029 |
| ABHD6 | abhydrolase domain containing 6 | 0.00498874 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.00497661 |
| KRT1 | keratin 1, type II | 0.00497314 |
| BAX | BCL2-associated X protein | 0.00496655 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.00495594 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00494629 |
| CBFB | core-binding factor, beta subunit | 0.00494134 |
| BIN1 | bridging integrator 1 | 0.00493801 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00493437 |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 0.004934 |
| TPM4 | tropomyosin 4 | 0.0049253 |
| RNF167 | ring finger protein 167 | 0.00492274 |
| SH2D4A | SH2 domain containing 4A | 0.00491573 |
| POPDC3 | popeye domain containing 3 | 0.00490989 |
| ZNF721 | zinc finger protein 721 | 0.0048993 |
| LPAR1 | lysophosphatidic acid receptor 1 | 0.00489647 |
| CALCA | calcitonin-related polypeptide alpha | 0.00489168 |
| UGT2A3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.00488362 |
| FGFR3 | fibroblast growth factor receptor 3 | 0.00487766 |
| TMEM176A | transmembrane protein 176A | 0.00487585 |
| OPHN1 | oligophrenin 1 | 0.00487462 |
| SYNJ2 | synaptojanin 2 | 0.0048728 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | 0.00486579 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.00486012 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | 0.00485719 |
| HAS2 | hyaluronan synthase 2 | 0.00485086 |
| DEFB1 | defensin, beta 1 | 0.00485065 |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | 0.00484569 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.00484535 |
| DMAC2L | distal membrane arm assembly component 2 like | 0.00484302 |
| ICAM3 | intercellular adhesion molecule 3 | 0.00484213 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00483801 |
| OXTR | oxytocin receptor | 0.00483622 |
| SARAF | store-operated calcium entry-associated regulatory factor | 0.00482129 |
| IL20RA | interleukin 20 receptor, alpha | 0.00481655 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 0.00480475 |
| LYRM1 | LYR motif containing 1 | 0.00480061 |
| CA12 | carbonic anhydrase XII | 0.00478955 |
| HAVCR1 | hepatitis A virus cellular receptor 1 | 0.00478694 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.00478115 |
| ARSL | arylsulfatase L | 0.0047795 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 | 0.00477611 |
| IRF8 | interferon regulatory factor 8 | 0.00474639 |
| KIAA0226L | KIAA0226-like | 0.00474197 |
| PPIF | peptidylprolyl isomerase F | 0.00473814 |
| PRUNE2 | prune homolog 2 (Drosophila) | 0.00473372 |
| LCE2B | late cornified envelope 2B | 0.0047277 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00471339 |
| NPR3 | natriuretic peptide receptor 3 | 0.00471156 |
| NOX1 | NADPH oxidase 1 | 0.00471099 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 0.00470849 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | 0.00469915 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00469883 |
| SCG5 | secretogranin V | 0.00469462 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00469391 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00468736 |
| PTGES | prostaglandin E synthase | 0.00468467 |
| PLLP | plasmolipin | 0.00467906 |
| TMEM63A | transmembrane protein 63A | 0.00466644 |
| TSEN34 | TSEN34 tRNA splicing endonuclease subunit | 0.00466513 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00466255 |
| MB | myoglobin | 0.00465271 |
| FSTL1 | follistatin-like 1 | 0.00463497 |
| SUMO3 | small ubiquitin-like modifier 3 | 0.00461327 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming | 0.00461312 |
| MAGT1 | magnesium transporter 1 | 0.00460527 |
| AKIRIN1 | akirin 1 | 0.00459873 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 0.00458943 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00458757 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00458738 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.00457909 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 | 0.00456958 |
| PRMT1 | protein arginine methyltransferase 1 | 0.00456271 |
| ENO1 | enolase 1, (alpha) | 0.00455628 |
| DEFB4A | defensin, beta 4A | 0.00455364 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 | 0.00454994 |
| CD22 | CD22 molecule | 0.00454554 |
| EFHD1 | EF-hand domain family, member D1 | 0.00454507 |
| TRAF5 | TNF receptor-associated factor 5 | 0.00454453 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00454336 |
| SDC4 | syndecan 4 | 0.00453623 |
| GOT2 | glutamic-oxaloacetic transaminase 2, mitochondrial | 0.00453564 |
| PRR11 | proline rich 11 | 0.00453163 |
| Symbol | Name | Standardized Value |
|---|---|---|
| WDR7 | WD repeat domain 7 | -0.0157862 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0124246 |
| TGM2 | transglutaminase 2 | -0.012214 |
| PDGFC | platelet derived growth factor C | -0.0117404 |
| MGP | matrix Gla protein | -0.0112444 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0112088 |
| ASPN | asporin | -0.0110685 |
| TPSAB1 | tryptase alpha/beta 1 | -0.0110315 |
| AGR2 | anterior gradient 2 | -0.0106968 |
| LTF | lactotransferrin | -0.0106887 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -0.0105557 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0103484 |
| FBLN1 | fibulin 1 | -0.0102448 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.0101001 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00998979 |
| S100A8 | S100 calcium binding protein A8 | -0.00982301 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.00923073 |
| DEPTOR | DEP domain containing MTOR-interacting protein | -0.0089839 |
| CFD | complement factor D (adipsin) | -0.00870763 |
| MAOA | monoamine oxidase A | -0.00864846 |
| C10ORF10 | chromosome 10 open reading frame 10 | -0.00854295 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0084322 |
| IL1RN | interleukin 1 receptor antagonist | -0.00840166 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00834505 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.007876 |
| KRT19 | keratin 19, type I | -0.00782279 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00768716 |
| LYST | lysosomal trafficking regulator | -0.00763849 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00763377 |
| KRT13 | keratin 13, type I | -0.00760146 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00757889 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 | -0.0074607 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | -0.00741277 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00735423 |
| MECOM | MDS1 and EVI1 complex locus | -0.0072661 |
| PEG10 | paternally expressed 10 | -0.00726582 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | -0.00722625 |
| ANXA1 | annexin A1 | -0.0072067 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.00719935 |
| CLEC11A | C-type lectin domain family 11, member A | -0.00719466 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00717795 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.00712304 |
| AZU1 | azurocidin 1 | -0.00711136 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.00707736 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.00698375 |
| IRS2 | insulin receptor substrate 2 | -0.00693966 |
| PLN | phospholamban | -0.00693671 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00685154 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00684601 |
| FLNA | filamin A, alpha | -0.00681674 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -0.00679824 |
| GSTA1 | glutathione S-transferase alpha 1 | -0.00675458 |
| H1-2 | H1.2 linker histone, cluster member | -0.00672344 |
| FXYD3 | FXYD domain containing ion transport regulator 3 | -0.00670886 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.00669271 |
| EMP1 | epithelial membrane protein 1 | -0.00659306 |
| ARG2 | arginase 2 | -0.00657701 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00657462 |
| KRT6A | keratin 6A, type II | -0.00652867 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | -0.00648874 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.00647695 |
| FAM117A | family with sequence similarity 117, member A | -0.00647127 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00646029 |
| PLAU | plasminogen activator, urokinase | -0.00643827 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00642771 |
| LBH | limb bud and heart development | -0.00640685 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0063796 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00632477 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00632392 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00631512 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00629651 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.00628062 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | -0.00625746 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.00619088 |
| S100A2 | S100 calcium binding protein A2 | -0.0061858 |
| RNF6 | ring finger protein (C3H2C3 type) 6 | -0.0061357 |
| BCR | breakpoint cluster region | -0.00611111 |
| GNAS | GNAS complex locus | -0.00610661 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | -0.00610428 |
| PALLD | palladin, cytoskeletal associated protein | -0.00605905 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0060213 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00602037 |
| NBEA | neurobeachin | -0.00598015 |
| MT1X | metallothionein 1X | -0.00596274 |
| TXNL1 | thioredoxin-like 1 | -0.00595403 |
| RGCC | regulator of cell cycle | -0.00591848 |
| LIPT1 | lipoyltransferase 1 | -0.00591223 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.00590374 |
| PGD | phosphogluconate dehydrogenase | -0.00589958 |
| NXN | nucleoredoxin | -0.00588828 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | -0.00588286 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.00587083 |
| AFF1 | AF4/FMR2 family, member 1 | -0.00586638 |
| HIST1H2AC | histone cluster 1, H2ac | -0.00586036 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00584931 |
| AEBP1 | AE binding protein 1 | -0.00583882 |
| MBD2 | methyl-CpG binding domain protein 2 | -0.00581726 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.00580979 |
| TRIB2 | tribbles pseudokinase 2 | -0.00579765 |
| CS | citrate synthase | -0.00579481 |
| PCP4 | Purkinje cell protein 4 | -0.00576229 |
| KRT7 | keratin 7, type II | -0.00574269 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | -0.00574086 |
| SLC38A6 | solute carrier family 38, member 6 | -0.00570432 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00570234 |
| TCEAL2 | transcription elongation factor A (SII)-like 2 | -0.00570133 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.00567808 |
| CSTA | cystatin A (stefin A) | -0.0056703 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00566312 |
| GLUL | glutamate-ammonia ligase | -0.00565528 |
| BPGM | 2,3-bisphosphoglycerate mutase | -0.00565504 |
| STK26 | serine/threonine protein kinase 26 | -0.00561905 |
| ASS1 | argininosuccinate synthase 1 | -0.00561573 |
| MFAP5 | microfibrillar associated protein 5 | -0.00561009 |
| MAGED1 | melanoma antigen family D1 | -0.00558151 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.0055677 |
| S100A9 | S100 calcium binding protein A9 | -0.00556453 |
| PLCL2 | phospholipase C-like 2 | -0.0055551 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00555432 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.00554922 |
| MT1G | metallothionein 1G | -0.0055403 |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) | -0.00553729 |
| IPO13 | importin 13 | -0.0055337 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0055185 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00551558 |
| BTG2 | BTG family, member 2 | -0.00550631 |
| TRRAP | transformation/transcription domain-associated protein | -0.00549789 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00549343 |
| ZBED2 | zinc finger, BED-type containing 2 | -0.0054867 |
| MAMLD1 | mastermind-like domain containing 1 | -0.00545693 |
| HSPA1A | heat shock 70kDa protein 1A | -0.00545192 |
| COG5 | component of oligomeric golgi complex 5 | -0.00544298 |
| SQLE | squalene epoxidase | -0.00544158 |
| RAB38 | RAB38, member RAS oncogene family | -0.00543853 |
| HBD | hemoglobin, delta | -0.00539437 |
| MMP12 | matrix metallopeptidase 12 | -0.00538682 |
| RBM47 | RNA binding motif protein 47 | -0.00537698 |
| CADM1 | cell adhesion molecule 1 | -0.00537551 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.00534956 |
| PRTN3 | proteinase 3 | -0.00534396 |
| TMEM131L | transmembrane 131 like | -0.00533487 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00532237 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00532027 |
| TADA2A | transcriptional adaptor 2A | -0.00530835 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0053021 |
| PLTP | phospholipid transfer protein | -0.00529551 |
| OPN3 | opsin 3 | -0.00526335 |
| AOC3 | amine oxidase, copper containing 3 | -0.00525901 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.00525642 |
| CNN1 | calponin 1, basic, smooth muscle | -0.00525537 |
| FOCAD | focadhesin | -0.00524255 |
| RRM2 | ribonucleotide reductase M2 | -0.00524154 |
| TCAF1 | TRPM8 channel-associated factor 1 | -0.00523824 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | -0.00523142 |
| ELP1 | elongator acetyltransferase complex subunit 1 | -0.00520808 |
| SH3YL1 | SH3 and SYLF domain containing 1 | -0.00520132 |
| SCPEP1 | serine carboxypeptidase 1 | -0.00519178 |
| CCN3 | cellular communication network factor 3 | -0.00516773 |
| CTSV | cathepsin V | -0.00516411 |
| LXN | latexin | -0.00515082 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00513764 |
| CD9 | CD9 molecule | -0.00512405 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.00511678 |
| KRT18 | keratin 18, type I | -0.00511498 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00510598 |
| CEP68 | centrosomal protein 68kDa | -0.00508639 |
| TXNL4B | thioredoxin-like 4B | -0.00508496 |
| DES | desmin | -0.00508249 |
| SRPK2 | SRSF protein kinase 2 | -0.00506507 |
| GATAD1 | GATA zinc finger domain containing 1 | -0.00506481 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00506389 |
| UGP2 | UDP-glucose pyrophosphorylase 2 | -0.00504689 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.00504503 |
| FMOD | fibromodulin | -0.00500948 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha | -0.00500546 |
| ASPH | aspartate beta-hydroxylase | -0.00499428 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00499199 |
| KYNU | kynureninase | -0.00496212 |
| IL27RA | interleukin 27 receptor, alpha | -0.00495947 |
| SLC25A4 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 | -0.00494586 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.00494032 |
| XK | X-linked Kx blood group | -0.00492838 |
| ARL8B | ADP-ribosylation factor-like 8B | -0.00492231 |
| DROSHA | drosha, ribonuclease type III | -0.00491582 |
| GOLGA4 | golgin A4 | -0.00491429 |
| PIR | pirin (iron-binding nuclear protein) | -0.00490943 |
| ORC5 | origin recognition complex, subunit 5 | -0.00489909 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00489489 |
| HIRA | histone cell cycle regulator | -0.0048906 |
| HMGB1 | high mobility group box 1 | -0.00484845 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | -0.00484547 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -0.00484117 |
| ABHD4 | abhydrolase domain containing 4 | -0.00483264 |
| CD163 | CD163 molecule | -0.00480078 |
| RANBP2 | RAN binding protein 2 | -0.00479314 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.00479081 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 | -0.00478365 |
| ZNF467 | zinc finger protein 467 | -0.00478132 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | -0.00477985 |
| SIX1 | SIX homeobox 1 | -0.00477703 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00476871 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00476721 |
| NOTCH3 | notch 3 | -0.00476721 |
| G0S2 | G0/G1 switch 2 | -0.00476317 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0047551 |
| KDM3B | lysine (K)-specific demethylase 3B | -0.00474858 |
| EHMT2 | euchromatic histone-lysine N-methyltransferase 2 | -0.00473881 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00473386 |
| FCER1G | Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide | -0.00472377 |
| FAM3C | family with sequence similarity 3, member C | -0.004704 |
| TSPAN7 | tetraspanin 7 | -0.00470028 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.00469981 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00469764 |
| NPC2 | Niemann-Pick disease, type C2 | -0.00469342 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 | -0.0046901 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | -0.00468889 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.00467694 |
| TMEM132A | transmembrane protein 132A | -0.00466364 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 | -0.00465223 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00464921 |
| TBC1D31 | TBC1 domain family, member 31 | -0.0046474 |
| MSMB | microseminoprotein, beta- | -0.00464363 |
| CD14 | CD14 molecule | -0.00462986 |
| E2F2 | E2F transcription factor 2 | -0.00461982 |
| C3 | complement component 3 | -0.00460496 |
| EPCAM | epithelial cell adhesion molecule | -0.00460084 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 | -0.00459683 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00459604 |
| CLIC2 | chloride intracellular channel 2 | -0.00459119 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00457719 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00457289 |
| ADIPOQ | adiponectin, C1Q and collagen domain containing | -0.00457213 |
| MRTFB | myocardin related transcription factor B | -0.00456504 |
| KLHDC10 | kelch domain containing 10 | -0.00456353 |
| RAB2A | RAB2A, member RAS oncogene family | -0.00455806 |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 | -0.00455072 |
| SVIL | supervillin | -0.00454356 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00454075 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.00453552 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | -0.00452385 |
| SPEN | spen family transcriptional repressor | -0.00451559 |
| KIFAP3 | kinesin-associated protein 3 | -0.00451139 |
| CENPC | centromere protein C | -0.00450006 |
| FKBP11 | FK506 binding protein 11, 19 kDa | -0.00449359 |
| CDC20 | cell division cycle 20 | -0.00449145 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00449029 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00448591 |
| ATP5MF | ATP synthase membrane subunit f | -0.00446919 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00446757 |
