GAL Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description galanin/GMAP prepropeptide|Galanin is small neuropeptide that functions as a cellular messenger within the central and peripheral nervous systems, modulating diverse physiologic functions (Mechenthaler, 2008 [PubMed 18500643]).[supplied by OMIM, Jan 2009] (NCBI Entrez Gene Database, 51083)
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Genes

318 genes differentially expressed following the GAL gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TACR2 tachykinin receptor 2 3.46659
MYO16 myosin XVI 3.46659
LRRC46 leucine rich repeat containing 46 3.46659
ALLC allantoicase 3.46659
ARR3 arrestin 3, retinal (X-arrestin) 3.46659
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 3.46659
FAM240B family with sequence similarity 240 member B 3.46659
ERICH4 glutamate-rich 4 3.46659
HAO2 hydroxyacid oxidase 2 (long chain) 3.46659
GPRC5D G protein-coupled receptor, class C, group 5, member D 3.46659
BTN1A1 butyrophilin, subfamily 1, member A1 3.46659
WNT9B wingless-type MMTV integration site family, member 9B 3.46659
CRX cone-rod homeobox 3.46659
SHISA3 shisa family member 3 3.46659
OR52N4 olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene) 3.46659
SCN10A sodium channel, voltage gated, type X alpha subunit 3.46659
ZNF831 zinc finger protein 831 3.46659
ECM1 extracellular matrix protein 1 3.46659
ROM1 retinal outer segment membrane protein 1 3.46659
CIMIP1 ciliary microtubule inner protein 1 3.46659
SKOR2 SKI family transcriptional corepressor 2 3.46659
CHRDL2 chordin-like 2 3.46659
HBA2 hemoglobin, alpha 2 3.44483
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.44483
PCDHA8 protocadherin alpha 8 3.44483
LIPK lipase, family member K 3.44483
EDAR ectodysplasin A receptor 3.44483
CLDN2 claudin 2 3.44483
PCDHB10 protocadherin beta 10 3.44483
PTPRC protein tyrosine phosphatase, receptor type, C 3.44483
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.44483
PCDHA3 protocadherin alpha 3 3.44483
FOXD1 forkhead box D1 3.44483
ACOT1 acyl-CoA thioesterase 1 3.44483
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 3.44483
CABP4 calcium binding protein 4 3.44483
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 3.44483
SLC35G6 solute carrier family 35, member G6 3.44483
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 3.44483
CXORF65 chromosome X open reading frame 65 3.44483
SKOR1 SKI family transcriptional corepressor 1 3.44483
MUC5B mucin 5B, oligomeric mucus/gel-forming 3.44483
DSG3 desmoglein 3 3.44483
ASB10 ankyrin repeat and SOCS box containing 10 3.44483
SCNN1G sodium channel, non voltage gated 1 gamma subunit 3.44483
MYO7B myosin VIIB 3.44483
PCDHB7 protocadherin beta 7 3.44483
MGAM2 maltase-glucoamylase 2 (putative) 3.44483
AGTR1 angiotensin II receptor, type 1 3.44483
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha 3.44483
CLEC12A C-type lectin domain family 12, member A 3.44483
NR1H4 nuclear receptor subfamily 1, group H, member 4 3.44483
GPR55 G protein-coupled receptor 55 3.44483
PI16 peptidase inhibitor 16 3.44483
LIPH lipase, member H 3.44483
NXPH3 neurexophilin 3 3.44483
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 3.44483
LOC124906892 uncharacterized LOC124906892 3.44483
GSTT4 glutathione S-transferase theta 4 3.44483
CCN5 cellular communication network factor 5 3.44483
SMIM40 small integral membrane protein 40 3.44483
SQOR sulfide quinone oxidoreductase 3.44483
MT3 metallothionein 3 3.44483
OTOS otospiralin 3.44483
ZNF726 zinc finger protein 726 3.44483
ROPN1L rhophilin associated tail protein 1-like 3.44483
PNLIPRP3 pancreatic lipase-related protein 3 3.44483
SEPTIN12 septin 12 3.44483
PEAK3 PEAK family member 3 3.44483
LOC124900192 uncharacterized LOC124900192 3.44483
LOC107986837 uncharacterized LOC107986837 3.44483
KRABD1 KRAB domain containing 1 3.44483
CATSPERH catsper channel auxiliary subunit eta 3.44483
CIMIP2B ciliary microtubule inner protein 2B 3.44483
FAM240C family with sequence similarity 240 member C 3.44483
PRRT1B proline rich transmembrane protein 1B 3.44483
SMIM43 small integral membrane protein 43 3.44483
LHFPL7 LHFPL tetraspan subfamily member 7 3.44483
FRG2C FSHD region gene 2 family, member C 3.44483
SPRR2D small proline-rich protein 2D 3.44483
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 3.44483
GJD2 gap junction protein, delta 2, 36kDa 3.44483
C1QTNF9 C1q and tumor necrosis factor related protein 9 3.44483
AMY2A amylase, alpha 2A (pancreatic) 3.44483
TLR6 toll-like receptor 6 3.44483
LRIT2 leucine-rich repeat, immunoglobulin-like and transmembrane domains 2 3.44483
OR2AT4 olfactory receptor, family 2, subfamily AT, member 4 3.44483
OR51B5 olfactory receptor, family 51, subfamily B, member 5 3.44483
DAO D-amino-acid oxidase 3.44483
VSX2 visual system homeobox 2 3.44483
PGA5 pepsinogen 5, group I (pepsinogen A) 3.44483
STARD6 StAR-related lipid transfer (START) domain containing 6 3.44483
TBC1D3B TBC1 domain family, member 3B 3.44483
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10 3.44483
FOXC1 forkhead box C1 3.44483
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.44483
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 3.44483
ABCA9 ATP-binding cassette, sub-family A (ABC1), member 9 3.44483
GATA6 GATA binding protein 6 3.44483
ACE2 angiotensin I converting enzyme 2 3.44483
MOV10L1 Mov10 RISC complex RNA helicase like 1 3.44483
CHRD chordin 3.44483
PHACTR3 phosphatase and actin regulator 3 3.44483
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 3.44483
PRM1 protamine 1 3.44483
KRT222 keratin 222, type II 3.44483
CRYBB2 crystallin, beta B2 3.44483
HHATL hedgehog acyltransferase-like 3.44483
SPANXC SPANX family, member C 3.44483
KRTAP5-11 keratin associated protein 5-11 3.44483
ITGA8 integrin, alpha 8 3.44483
OR51V1 olfactory receptor, family 51, subfamily V, member 1 3.44483
CLPS colipase, pancreatic 3.44483
PLA2G4D phospholipase A2, group IVD (cytosolic) 3.44483
PRSS55 protease, serine, 55 3.44483
DBX2 developing brain homeobox 2 3.44483
PRR15L proline rich 15-like 3.44483
CARD9 caspase recruitment domain family, member 9 3.44483
SLITRK1 SLIT and NTRK-like family, member 1 3.44483
FITM1 fat storage-inducing transmembrane protein 1 3.44483
WFDC6 WAP four-disulfide core domain 6 3.44483
SPINK9 serine peptidase inhibitor, Kazal type 9 3.44483
KRTAP2-3 keratin associated protein 2-3 3.44483
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 3.44483
INSL3 insulin-like 3 (Leydig cell) 3.44483
BCL2L15 BCL2-like 15 3.44483
SOSTDC1 sclerostin domain containing 1 3.44483
SCNN1B sodium channel, non voltage gated 1 beta subunit 3.44483
OCM oncomodulin 3.44483
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 3.44483
C8A complement component 8, alpha polypeptide 3.44483
PTPN20 protein tyrosine phosphatase, non-receptor type 20 3.44483
SIRPG signal-regulatory protein gamma 3.44483
KLK2 kallikrein-related peptidase 2 3.44483
KLK11 kallikrein-related peptidase 11 3.44483
P2RY10 purinergic receptor P2Y, G-protein coupled, 10 3.44483
P2RY13 purinergic receptor P2Y, G-protein coupled, 13 3.44483
LMOD3 leiomodin 3 (fetal) 3.44483
EVPLL envoplakin-like 3.44483
LRRC74A leucine rich repeat containing 74A 3.44483
GRAPL GRB2-related adaptor protein-like 3.44483
PRR27 proline rich 27 3.44483
TAL1 T-cell acute lymphocytic leukemia 1 3.44483
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 3.44483
C14ORF180 chromosome 14 open reading frame 180 3.44483
OR5A2 olfactory receptor, family 5, subfamily A, member 2 3.44483
MS4A18 membrane-spanning 4-domains, subfamily A, member 18 3.44483
NR2F1 nuclear receptor subfamily 2, group F, member 1 3.44483
IL23R interleukin 23 receptor 3.44483
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 3.44483
SPP2 secreted phosphoprotein 2, 24kDa 3.44483
KIAA1755 KIAA1755 3.44483
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 3.44483
GAGE12F G antigen 12F 3.44483
ANKK1 ankyrin repeat and kinase domain containing 1 3.44483
PRDM12 PR domain containing 12 3.44483
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 3.44483
PBOV1 prostate and breast cancer overexpressed 1 3.44483
FCAR Fc fragment of IgA receptor 3.44483
STOML3 stomatin (EPB72)-like 3 3.44483
GPRC5A G protein-coupled receptor, class C, group 5, member A 3.44483
TAS2R1 taste receptor, type 2, member 1 3.44483
TRAF3IP3 TRAF3 interacting protein 3 3.44483
LRRC31 leucine rich repeat containing 31 3.44483
TMEM132C transmembrane protein 132C 3.44483
NKX3-1 NK3 homeobox 1 3.42636
PRTN3 proteinase 3 3.31075
AGBL4 ATP/GTP binding protein-like 4 2.93361
OVOL3 ovo-like zinc finger 3 2.93361
MYL7 myosin, light chain 7, regulatory 2.89086
WBP2NL WBP2 N-terminal like 2.86682
USP16 ubiquitin specific peptidase 16 2.74601
HAVCR2 hepatitis A virus cellular receptor 2 2.68059
TSLIG3A tRNA splicing ligase complex subunit 3A 2.65176
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha 2.62662
SHMT1 serine hydroxymethyltransferase 1 (soluble) 2.55398
DTX3 deltex 3, E3 ubiquitin ligase 2.55347
CS citrate synthase 2.53617
ARRB1 arrestin, beta 1 2.48267
GAS6 growth arrest-specific 6 2.45763
RAB11FIP5 RAB11 family interacting protein 5 (class I) 2.41437
CNTFR ciliary neurotrophic factor receptor 2.40767
OR4D1 olfactory receptor, family 4, subfamily D, member 1 2.40767
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11 2.40767
BHLHA9 basic helix-loop-helix family, member a9 2.38763
CAVIN1 caveolae associated protein 1 2.38648
NUMB numb homolog (Drosophila) 2.38035
OPN3 opsin 3 2.33321
NPHS1 nephrosis 1, congenital, Finnish type (nephrin) 2.33321
STYXL2 serine/threonine/tyrosine interacting like 2 2.32702
RANBP6 RAN binding protein 6 2.31742
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 2.31423
NKD1 naked cuticle homolog 1 (Drosophila) 2.30397
GJB5 gap junction protein, beta 5, 31.1kDa 2.28755
FYCO1 FYVE and coiled-coil domain containing 1 2.27228
CYP39A1 cytochrome P450, family 39, subfamily A, polypeptide 1 2.26147
RAB33A RAB33A, member RAS oncogene family 2.24679
RB1CC1 RB1-inducible coiled-coil 1 2.2392
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G 2.23506
NRXN2 neurexin 2 2.22064
EMP3 epithelial membrane protein 3 2.20071
SORBS2 sorbin and SH3 domain containing 2 2.20001
SRPK2 SRSF protein kinase 2 2.17399
METTL4 methyltransferase like 4 2.16997
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 2.16997
CIPC CLOCK-interacting pacemaker 2.10195
USP19 ubiquitin specific peptidase 19 2.099
SLC38A10 solute carrier family 38, member 10 2.09219
CFAP36 cilia and flagella associated protein 36 2.07219
DNAH11 dynein, axonemal, heavy chain 11 2.05317
TNNT2 troponin T type 2 (cardiac) 2.0511
CERS4 ceramide synthase 4 2.04217
METAP1 methionyl aminopeptidase 1 2.04084
NCAPH non-SMC condensin I complex, subunit H 2.02767
FAM217B family with sequence similarity 217, member B 2.02181
EYS eyes shut homolog (Drosophila) 2.00161

decreased expression

Symbol Name Standardized Value
VSIG1 V-set and immunoglobulin domain containing 1 -3.46659
EMP1 epithelial membrane protein 1 -3.46644
RBM20 RNA binding motif protein 20 -3.46644
C5ORF47 chromosome 5 open reading frame 47 -3.46644
H2BC12 H2B clustered histone 12 -3.44398
EDN1 endothelin 1 -3.44154
GRK7 G protein-coupled receptor kinase 7 -3.44154
VCX3A variable charge, X-linked 3A -3.44154
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa -3.44154
F11 coagulation factor XI -3.44154
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 -3.44154
IRGM immunity-related GTPase family, M -3.44154
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C -3.44154
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 -3.44154
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -3.44154
ARHGAP40 Rho GTPase activating protein 40 -3.44154
COLEC10 collectin sub-family member 10 (C-type lectin) -3.44154
NR2F2 nuclear receptor subfamily 2, group F, member 2 -3.44154
HAL histidine ammonia-lyase -3.44154
C17ORF78 chromosome 17 open reading frame 78 -3.44154
OR2A25 olfactory receptor, family 2, subfamily A, member 25 -3.44154
DMP1 dentin matrix acidic phosphoprotein 1 -3.44154
CCR6 chemokine (C-C motif) receptor 6 -3.44154
SHC4 SHC (Src homology 2 domain containing) family, member 4 -3.44154
SLC26A7 solute carrier family 26 (anion exchanger), member 7 -3.14059
SEC24D SEC24 family member D -3.09249
PLK4 polo-like kinase 4 -3.08301
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 -3.04772
PRCP prolylcarboxypeptidase (angiotensinase C) -3.02527
ZNF816 zinc finger protein 816 -2.95369
MARCHF7 membrane associated ring-CH-type finger 7 -2.89086
CBFB core-binding factor, beta subunit -2.8773
SKAP1 src kinase associated phosphoprotein 1 -2.8553
GAL galanin/GMAP prepropeptide -2.82837
ASPNAT aspartate N-acetyltransferase -2.73889
CD200R1 CD200 receptor 1 -2.73889
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -2.70839
TEAD2 TEA domain family member 2 -2.70504
KAT14 lysine acetyltransferase 14 -2.6536
LMBR1 limb development membrane protein 1 -2.65141
POLR2H polymerase (RNA) II (DNA directed) polypeptide H -2.59435
GRIK5 glutamate receptor, ionotropic, kainate 5 -2.5913
TK1 thymidine kinase 1, soluble -2.54289
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -2.45667
ADGRG5 adhesion G protein-coupled receptor G5 -2.43105
MRPL14 mitochondrial ribosomal protein L14 -2.42717
PCDH20 protocadherin 20 -2.42657
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.40324
EGFLAM EGF-like, fibronectin type III and laminin G domains -2.35753
METTL24 methyltransferase like 24 -2.35753
CXCR5 chemokine (C-X-C motif) receptor 5 -2.35753
TMEM144 transmembrane protein 144 -2.35753
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -2.35753
MRPS31 mitochondrial ribosomal protein S31 -2.34432
SCAMP2 secretory carrier membrane protein 2 -2.34005
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 -2.33323
CGRRF1 cell growth regulator with ring finger domain 1 -2.32888
CCNC cyclin C -2.32702
SPSB2 splA/ryanodine receptor domain and SOCS box containing 2 -2.32267
PIERCE2 piercer of microtubule wall 2 -2.32262
ATXN2L ataxin 2-like -2.31582
MGST3 microsomal glutathione S-transferase 3 -2.31423
CRACR2B calcium release activated channel regulator 2B -2.27571
RPS27L ribosomal protein S27-like -2.26193
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit -2.26147
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like -2.24569
LCAT lecithin-cholesterol acyltransferase -2.24569
KRT18 keratin 18, type I -2.24569
MEP1B meprin A, beta -2.24569
METTL5 methyltransferase like 5 -2.23506
ASIC1 acid sensing (proton gated) ion channel 1 -2.21125
ZNF211 zinc finger protein 211 -2.18923
ARF1 ADP-ribosylation factor 1 -2.18761
IKZF2 IKAROS family zinc finger 2 (Helios) -2.18504
IFITM1 interferon induced transmembrane protein 1 -2.18156
PEX11G peroxisomal biogenesis factor 11 gamma -2.17537
CUTC cutC copper transporter -2.17537
LCA5 Leber congenital amaurosis 5 -2.17341
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme -2.17139
TMEM79 transmembrane protein 79 -2.16997
EPHA2 EPH receptor A2 -2.16997
ZNF750 zinc finger protein 750 -2.16997
NMBR neuromedin B receptor -2.16997
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) -2.16997
PTK2 protein tyrosine kinase 2 -2.16997
CDC123 cell division cycle 123 -2.16997
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 -2.16997
GOLGA6L4 golgin A6 family-like 4 -2.16997
TMEM190 transmembrane protein 190 -2.15094
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 -2.14527
ZNF570 zinc finger protein 570 -2.11094
ARSK arylsulfatase family, member K -2.099
HEATR1 HEAT repeat containing 1 -2.09219
SUCLG1 succinate-CoA ligase, alpha subunit -2.08337
PRICKLE2 prickle homolog 2 (Drosophila) -2.06348
PIGH phosphatidylinositol glycan anchor biosynthesis, class H -2.0568
ZNF329 zinc finger protein 329 -2.05426
TMSB10 thymosin beta 10 -2.0384
FGF11 fibroblast growth factor 11 -2.03427
CYCS cytochrome c, somatic -2.02163
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.00161
RAB3IL1 RAB3A interacting protein (rabin3)-like 1 -2.00161