GAS1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description growth arrest-specific 1|Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2619)
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Genes

355 genes differentially expressed following the GAS1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
TTC22 tetratricopeptide repeat domain 22 3.35274
ALX1 ALX homeobox 1 3.35274
SERINC4 serine incorporator 4 3.35274
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 3.35274
CELA3B chymotrypsin-like elastase family, member 3B 3.35274
HHIPL2 HHIP-like 2 3.35274
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 3.35274
CX3CL1 chemokine (C-X3-C motif) ligand 1 3.35274
VWA3A von Willebrand factor A domain containing 3A 3.35274
ERMN ermin, ERM-like protein 3.35274
DLK1 delta-like 1 homolog (Drosophila) 3.35274
SCEL sciellin 3.35274
C17ORF113 chromosome 17 open reading frame 113 3.35274
JAML junction adhesion molecule like 3.35274
ATP5MGL ATP synthase membrane subunit g like 3.35274
CXORF58 chromosome X open reading frame 58 3.35274
GRM6 glutamate receptor, metabotropic 6 3.35274
TBX22 T-box 22 3.35274
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 3.31537
PI16 peptidase inhibitor 16 3.31537
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 3.31537
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.31537
NEU4 sialidase 4 3.31537
CABP4 calcium binding protein 4 3.31537
DMRTC1B DMRT-like family C1B 3.31537
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 3.31537
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 3.31537
SH2D6 SH2 domain containing 6 3.31537
TSGA13 testis specific, 13 3.31537
PRR18 proline rich 18 3.31537
FABP1 fatty acid binding protein 1, liver 3.31537
MFAP5 microfibrillar associated protein 5 3.31537
ADAD2 adenosine deaminase domain containing 2 3.31537
ASGR2 asialoglycoprotein receptor 2 3.31537
KLLN killin, p53-regulated DNA replication inhibitor 3.31537
AIPL1 aryl hydrocarbon receptor interacting protein-like 1 3.31537
EPHB3 EPH receptor B3 3.31537
KRTAP5-9 keratin associated protein 5-9 3.31537
NPC1L1 NPC1-like 1 3.31537
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 3.31537
PODN podocan 3.31537
CAPS calcyphosine 3.31537
ATOH1 atonal homolog 1 (Drosophila) 3.31537
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 3.31537
MYOM3 myomesin 3 3.31537
NOTUM notum pectinacetylesterase homolog (Drosophila) 3.31537
C1ORF141 chromosome 1 open reading frame 141 3.31537
RGPD4 RANBP2-like and GRIP domain containing 4 3.31537
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 3.31537
GNRH2 gonadotropin-releasing hormone 2 3.31537
LRRC63 leucine rich repeat containing 63 3.31537
CRYGB crystallin, gamma B 3.31537
ABRA actin binding Rho activating protein 3.31537
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 3.31537
OR2I1 olfactory receptor family 2 subfamily I member 1 (gene/pseudogene) 3.31537
OTOR otoraplin 3.31537
SPRR2D small proline-rich protein 2D 3.31537
OR6F1 olfactory receptor, family 6, subfamily F, member 1 3.31537
WDR64 WD repeat domain 64 3.31537
RDH8 retinol dehydrogenase 8 (all-trans) 3.31537
SRPK3 SRSF protein kinase 3 3.31537
OR51M1 olfactory receptor, family 51, subfamily M, member 1 3.31537
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 3.31537
ELOVL3 ELOVL fatty acid elongase 3 3.31537
ADGRG7 adhesion G protein-coupled receptor G7 3.31537
NOTCH2NLB notch 2 N-terminal like B 3.31537
H4C15 H4 clustered histone 15 3.31537
C20ORF204 chromosome 20 open reading frame 204 3.31537
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 3.31537
GLYATL1B glycine-N-acyltransferase like 1B 3.31537
RTL9 retrotransposon Gag like 9 3.31537
SMIM40 small integral membrane protein 40 3.31537
YIPF7 Yip1 domain family, member 7 3.31537
ZNF705A zinc finger protein 705A 3.31537
KL klotho 3.31537
LTF lactotransferrin 3.31537
NXPE1 neurexophilin and PC-esterase domain family, member 1 3.31537
IRF8 interferon regulatory factor 8 3.31537
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 3.31537
ARL5C ADP-ribosylation factor-like 5C 3.31537
PCDHA2 protocadherin alpha 2 3.31537
SYCP2 synaptonemal complex protein 2 3.31537
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 3.31537
HRH4 histamine receptor H4 3.31537
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 3.31537
CHRD chordin 3.31537
TAS1R2 taste receptor, type 1, member 2 3.31537
FMR1NB fragile X mental retardation 1 neighbor 3.31537
BLNK B-cell linker 3.31537
S100G S100 calcium binding protein G 3.31537
CCR4 chemokine (C-C motif) receptor 4 3.31537
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.31537
DSG1 desmoglein 1 3.31537
OR7C1 olfactory receptor, family 7, subfamily C, member 1 3.31537
RNF17 ring finger protein 17 3.31537
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 3.31537
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.31537
CCL22 chemokine (C-C motif) ligand 22 3.31537
GAL3ST2 galactose-3-O-sulfotransferase 2 3.31537
FAM209A family with sequence similarity 209, member A 3.31537
CTXN2 cortexin 2 3.31537
ARL13A ADP-ribosylation factor-like 13A 3.31537
A3GALT2 alpha 1,3-galactosyltransferase 2 3.31537
KRT3 keratin 3, type II 3.31537
SLC25A52 solute carrier family 25, member 52 3.31537
MORC1 MORC family CW-type zinc finger 1 3.31537
RBM24 RNA binding motif protein 24 3.31537
KRT17 keratin 17, type I 3.31537
ZNF474 zinc finger protein 474 3.31537
TPPP3 tubulin polymerization-promoting protein family member 3 3.31537
CLIC3 chloride intracellular channel 3 3.31537
MR1 major histocompatibility complex, class I-related 3.31537
CNTF ciliary neurotrophic factor 3.31537
NIPAL4 NIPA-like domain containing 4 3.31537
PSKH2 protein serine kinase H2 3.31537
TRADD TNFRSF1A-associated via death domain 3.31537
TMEM202 transmembrane protein 202 3.31537
PRM1 protamine 1 3.31537
CYSLTR1 cysteinyl leukotriene receptor 1 3.31537
MCCD1 mitochondrial coiled-coil domain 1 3.31537
SEC14L3 SEC14-like 3 (S. cerevisiae) 3.31537
ASTL astacin-like metallo-endopeptidase (M12 family) 3.31537
HHLA2 HERV-H LTR-associating 2 3.31537
AQP7 aquaporin 7 3.31537
BTNL9 butyrophilin-like 9 3.31537
SLCO2B1 solute carrier organic anion transporter family, member 2B1 3.31537
S100A14 S100 calcium binding protein A14 3.31537
GSTA2 glutathione S-transferase alpha 2 3.31537
SLC38A8 solute carrier family 38, member 8 3.31537
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 3.31537
TRPM1 transient receptor potential cation channel, subfamily M, member 1 3.31537
DMRTC1 DMRT-like family C1 3.31537
CIB3 calcium and integrin binding family member 3 3.31537
PADI1 peptidyl arginine deiminase, type I 3.31537
CSHL1 chorionic somatomammotropin hormone-like 1 3.31537
DRC1 dynein regulatory complex subunit 1 3.31537
TAS2R42 taste receptor, type 2, member 42 3.31537
TAS2R46 taste receptor, type 2, member 46 3.31537
MMP12 matrix metallopeptidase 12 3.31537
PDK4 pyruvate dehydrogenase kinase, isozyme 4 3.31537
ZNF831 zinc finger protein 831 3.31537
TMEM88 transmembrane protein 88 3.31537
ICAM2 intercellular adhesion molecule 2 3.31537
BTNL3 butyrophilin-like 3 3.31537
PPP1R27 protein phosphatase 1, regulatory subunit 27 3.31537
GCM2 glial cells missing homolog 2 (Drosophila) 3.31537
FAIM2 Fas apoptotic inhibitory molecule 2 3.31537
CHRM4 cholinergic receptor, muscarinic 4 3.31537
MYLK2 myosin light chain kinase 2 3.31537
SUN3 Sad1 and UNC84 domain containing 3 3.31537
OSR1 odd-skipped related transciption factor 1 3.31537
PFN4 profilin family, member 4 3.31537
TRIM7 tripartite motif containing 7 3.31537
SLC38A3 solute carrier family 38, member 3 3.31537
AQP1 aquaporin 1 (Colton blood group) 3.31537
CARD6 caspase recruitment domain family, member 6 3.31537
SHCBP1 SHC SH2-domain binding protein 1 3.26859
RBM23 RNA binding motif protein 23 3.17917
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 3.1607
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 3.07215
KPTN kaptin (actin binding protein) 2.97915
WDR35 WD repeat domain 35 2.8547
MRPS18A mitochondrial ribosomal protein S18A 2.79541
TUSC3 tumor suppressor candidate 3 2.77397
RAB5B RAB5B, member RAS oncogene family 2.75747
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin 2.60031
CLN5 ceroid-lipofuscinosis, neuronal 5 2.589
METTL8 methyltransferase like 8 2.57432
PRELID3A PRELI domain containing 3A 2.56387
TSBP1 testis expressed basic protein 1 2.52924
SPRED2 sprouty-related, EVH1 domain containing 2 2.46946
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 2.4509
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) 2.42727
EVL Enah/Vasp-like 2.42568
ANAPC2 anaphase promoting complex subunit 2 2.41769
PIGB phosphatidylinositol glycan anchor biosynthesis, class B 2.41769
ZPBP zona pellucida binding protein 2.39123
MS4A6E membrane-spanning 4-domains, subfamily A, member 6E 2.39123
LGSN lengsin, lens protein with glutamine synthetase domain 2.39123
EEPD1 endonuclease/exonuclease/phosphatase family domain containing 1 2.37925
ALOX15B arachidonate 15-lipoxygenase, type B 2.37141
LPCAT2 lysophosphatidylcholine acyltransferase 2 2.34032
KLF10 Kruppel-like factor 10 2.34032
ATXN3 ataxin 3 2.31831
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial) 2.31506
WASHC5 WASH complex subunit 5 2.28983
ANKRD54 ankyrin repeat domain 54 2.27093
MRFAP1 Morf4 family associated protein 1 2.25356
TPRKB TP53RK binding protein 2.24083
ZNF780A zinc finger protein 780A 2.22574
INCENP inner centromere protein antigens 135/155kDa 2.2045
DCAF4L1 DDB1 and CUL4 associated factor 4-like 1 2.19972
ENDOU endonuclease, polyU-specific 2.19972
ASIC4 acid sensing (proton gated) ion channel family member 4 2.19972
CCDC38 coiled-coil domain containing 38 2.19972
TRPV3 transient receptor potential cation channel, subfamily V, member 3 2.19972
SH3GL3 SH3-domain GRB2-like 3 2.18946
ADARB2 adenosine deaminase, RNA-specific, B2 (non-functional) 2.18755
FANCD2OS FANCD2 opposite strand 2.16465
CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 2.14689
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 2.12939
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6 2.12843
SLC5A12 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 2.11656
NPIPB7 nuclear pore complex interacting protein family, member B7 2.11656
PODNL1 podocan-like 1 2.11656
TRPM2 transient receptor potential cation channel, subfamily M, member 2 2.11656
COL19A1 collagen, type XIX, alpha 1 2.11656
RNF227 ring finger protein 227 2.11656
VSTM1 V-set and transmembrane domain containing 1 2.11656
LRRC36 leucine rich repeat containing 36 2.11656
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 2.11656
PKD1L1 polycystic kidney disease 1 like 1 2.11656
ARHGAP11A Rho GTPase activating protein 11A 2.07808
HYCC1 hyccin PI4KA lipid kinase complex subunit 1 2.06918
KDM6A lysine (K)-specific demethylase 6A 2.06436
SPINK8 serine peptidase inhibitor, Kazal type 8 (putative) 2.04708
ITPK1 inositol-tetrakisphosphate 1-kinase 2.04608
ZNF142 zinc finger protein 142 2.04253
RDH10 retinol dehydrogenase 10 (all-trans) 2.04253
DXO decapping exoribonuclease 2.03361

decreased expression

Symbol Name Standardized Value
TMT1B thiol methyltransferase 1B -3.35274
PRDM6 PR domain containing 6 -3.35274
SAXO4 stabilizer of axonemal microtubules 4 -3.35274
PCSK2 proprotein convertase subtilisin/kexin type 2 -3.35274
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 -3.35274
NXPH4 neurexophilin 4 -3.35274
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 -3.35274
LINC02798 long intergenic non-protein coding RNA 2798 -3.35274
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -3.3248
KCNK15 potassium channel, two pore domain subfamily K, member 15 -3.31537
LGALS7B lectin, galactoside-binding, soluble, 7B -3.31537
ULBP3 UL16 binding protein 3 -3.31537
FAM167A family with sequence similarity 167, member A -3.31537
DNAAF8 dynein axonemal assembly factor 8 -3.31537
ETNPPL ethanolamine-phosphate phospho-lyase -3.31537
ZNF467 zinc finger protein 467 -3.31537
YAE1 YAE1 maturation factor of ABCE1 -3.31537
OR2B6 olfactory receptor, family 2, subfamily B, member 6 -3.31537
TMC3 transmembrane channel-like 3 -3.31537
PLEK2 pleckstrin 2 -3.31537
NLRP10 NLR family, pyrin domain containing 10 -3.31537
R3HDML R3H domain containing-like -3.31537
LKAAEAR1 LKAAEAR motif containing 1 -3.31537
OXER1 oxoeicosanoid (OXE) receptor 1 -3.31537
RGL4 ral guanine nucleotide dissociation stimulator-like 4 -3.31537
MTTP microsomal triglyceride transfer protein -3.31537
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma -3.31537
LMO1 LIM domain only 1 (rhombotin 1) -3.31537
PCGF2 polycomb group ring finger 2 -3.31537
HSPA1L heat shock 70kDa protein 1-like -3.31537
TREH trehalase (brush-border membrane glycoprotein) -3.31537
UPK3B uroplakin 3B -3.31537
SLC25A34 solute carrier family 25, member 34 -3.31537
EFCAB12 EF-hand calcium binding domain 12 -3.31537
UPK3A uroplakin 3A -3.31537
ADCY10 adenylate cyclase 10 (soluble) -3.31537
SIX3 SIX homeobox 3 -3.31537
MEP1B meprin A, beta -3.31537
GBX1 gastrulation brain homeobox 1 -3.31537
LRRC24 leucine rich repeat containing 24 -3.31537
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 -3.31537
CSDC2 cold shock domain containing C2, RNA binding -3.31537
ANKRD55 ankyrin repeat domain 55 -3.31537
PCDHGA7 protocadherin gamma subfamily A, 7 -3.31537
RHOXF2 Rhox homeobox family, member 2 -3.31537
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A -3.31537
DYDC1 DPY30 domain containing 1 -3.31537
UTS2B urotensin 2B -3.31537
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H -3.31537
MON1A MON1 secretory trafficking family member A -3.14483
DNAJB14 DnaJ (Hsp40) homolog, subfamily B, member 14 -3.07477
C4ORF36 chromosome 4 open reading frame 36 -3.06374
CTNNA3 catenin (cadherin-associated protein), alpha 3 -3.05913
ZSWIM1 zinc finger, SWIM-type containing 1 -3.05879
ASNSD1 asparagine synthetase domain containing 1 -2.98153
ADI1 acireductone dioxygenase 1 -2.92467
LRRC19 leucine rich repeat containing 19 -2.90496
RPL13 ribosomal protein L13 -2.90074
CCNYL1 cyclin Y-like 1 -2.79594
GATAD1 GATA zinc finger domain containing 1 -2.79594
TUBB3 tubulin, beta 3 class III -2.69646
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein -2.63171
SSBP1 single-stranded DNA binding protein 1, mitochondrial -2.63171
ACTL6B actin-like 6B -2.60687
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -2.60491
WDR54 WD repeat domain 54 -2.60131
FICD FIC domain containing -2.60031
ACTG1 actin gamma 1 -2.5924
ABHD1 abhydrolase domain containing 1 -2.56407
RSPH9 radial spoke head 9 homolog (Chlamydomonas) -2.53694
VSIG10L V-set and immunoglobulin domain containing 10 like -2.52924
FAM151A family with sequence similarity 151, member A -2.52802
GUK1 guanylate kinase 1 -2.47912
METTL16 methyltransferase like 16 -2.44753
RPL8 ribosomal protein L8 -2.43613
ZNHIT2 zinc finger, HIT-type containing 2 -2.4109
UBE2A ubiquitin-conjugating enzyme E2A -2.38592
MEX3A mex-3 RNA binding family member A -2.3806
ZNF419 zinc finger protein 419 -2.36214
DRAM1 DNA-damage regulated autophagy modulator 1 -2.36214
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) -2.35018
BAK1 BCL2-antagonist/killer 1 -2.34311
AGA-DT AGA divergent transcript -2.34032
AQP4 aquaporin 4 -2.34032
RIPPLY2 ripply transcriptional repressor 2 -2.34032
PDCL2 phosducin-like 2 -2.34032
APOE apolipoprotein E -2.34032
CRYGS crystallin, gamma S -2.34032
KCTD11 potassium channel tetramerization domain containing 11 -2.34032
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 -2.3359
TRIM25 tripartite motif containing 25 -2.32734
NBPF19 neuroblastoma breakpoint family, member 19 -2.31961
GMFB glia maturation factor, beta -2.28867
RIBC2 RIB43A domain with coiled-coils 2 -2.28457
RADIL Ras association and DIL domains -2.24749
AKAP1 A kinase (PRKA) anchor protein 1 -2.24085
SLC66A1 solute carrier family 66 member 1 -2.22911
PABIR3 PABIR family member 3 -2.21233
DORIP1 dopamine receptor interacting protein 1 -2.20145
RPS25 ribosomal protein S25 -2.19972
LRP12 low density lipoprotein receptor-related protein 12 -2.18755
S100A11 S100 calcium binding protein A11 -2.18543
ASRGL1 asparaginase like 1 -2.18466
AP1S3 adaptor-related protein complex 1, sigma 3 subunit -2.17683
KDM5C lysine (K)-specific demethylase 5C -2.17424
PIWIL2 piwi-like RNA-mediated gene silencing 2 -2.17075
C16ORF54 chromosome 16 open reading frame 54 -2.16087
WDR70 WD repeat domain 70 -2.13345
INSIG1 insulin induced gene 1 -2.12807
CST3 cystatin C -2.1253
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -2.12429
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C -2.11656
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3 -2.11656
GRHL1 grainyhead-like 1 (Drosophila) -2.11656
ABCB10 ATP-binding cassette, sub-family B (MDR/TAP), member 10 -2.11656
AFTPH aftiphilin -2.11656
NOB1 NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) -2.11636
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 -2.11464
ACP1 acid phosphatase 1, soluble -2.10735
F8 coagulation factor VIII, procoagulant component -2.10368
UNC13D unc-13 homolog D (C. elegans) -2.08953
BOLA3 bolA family member 3 -2.06933
CHLSN cholesin -2.06918
SSBP4 single stranded DNA binding protein 4 -2.06593
TXNDC17 thioredoxin domain containing 17 -2.0608
SHISA4 shisa family member 4 -2.05812
EMC6 ER membrane protein complex subunit 6 -2.05365
HPS5 Hermansky-Pudlak syndrome 5 -2.05312
LEFTY1 left-right determination factor 1 -2.04708
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) -2.04608
WDR82 WD repeat domain 82 -2.04067
NUP85 nucleoporin 85kDa -2.03361
TXNDC9 thioredoxin domain containing 9 -2.01764
ZNF862 zinc finger protein 862 -2.00569
DKKL1 dickkopf-like 1 -2.0024