GATA1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description GATA binding protein 1 (globin transcription factor 1)|This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2623)
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Genes

322 genes differentially expressed following the GATA1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
NYX nyctalopin 3.34438
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 3.34438
OTOP2 otopetrin 2 3.34438
PCDHGB4 protocadherin gamma subfamily B, 4 3.34438
GATA3 GATA binding protein 3 3.34438
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 3.34438
NOD2 nucleotide-binding oligomerization domain containing 2 3.34438
GH1 growth hormone 1 3.34438
THRSP thyroid hormone responsive 3.34438
LRRC72 leucine rich repeat containing 72 3.34438
CSF3R colony stimulating factor 3 receptor (granulocyte) 3.34438
NKX3-1 NK3 homeobox 1 3.34438
LURAP1L leucine rich adaptor protein 1-like 3.34438
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 3.34438
DMTN dematin actin binding protein 3.34438
TAFA3 TAFA chemokine like family member 3 3.34438
FAM167A family with sequence similarity 167, member A 3.34438
RAD21L1 RAD21-like 1 (S. pombe) 3.34438
ZPBP zona pellucida binding protein 3.34438
KRTAP5-11 keratin associated protein 5-11 3.34438
TEX29 testis expressed 29 3.34438
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.34438
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 3.34438
MUC6 mucin 6, oligomeric mucus/gel-forming 3.34438
CLEC19A C-type lectin domain family 19, member A 3.28351
CELF6 CUGBP, Elav-like family member 6 3.28351
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.28351
CPLX4 complexin 4 3.28351
OSGIN1 oxidative stress induced growth inhibitor 1 3.28351
SOX18 SRY (sex determining region Y)-box 18 3.28351
PCDHB7 protocadherin beta 7 3.28351
SCGB3A1 secretoglobin, family 3A, member 1 3.28351
HCRTR1 hypocretin (orexin) receptor 1 3.28351
MAGEA9 melanoma antigen family A9 3.28351
PCDHB6 protocadherin beta 6 3.28351
LMO1 LIM domain only 1 (rhombotin 1) 3.28351
LRRC55 leucine rich repeat containing 55 3.28351
SOST sclerostin 3.28351
LOC102724877 uncharacterized LOC102724877 3.28351
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 3.28351
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 3.28351
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 3.28351
CSNK2A3 casein kinase 2, alpha 3 polypeptide 3.28351
ZNF683 zinc finger protein 683 3.28351
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.28351
SMIM5 small integral membrane protein 5 3.28351
SFTPB surfactant protein B 3.28351
SLC23A3 solute carrier family 23, member 3 3.28351
TAS2R8 taste receptor, type 2, member 8 3.28351
POSTN periostin, osteoblast specific factor 3.28351
GRIA2 glutamate receptor, ionotropic, AMPA 2 3.28351
DMRTC1B DMRT-like family C1B 3.28351
PAX4 paired box 4 3.28351
HBA1 hemoglobin, alpha 1 3.28351
GALP galanin-like peptide 3.28351
KNG1 kininogen 1 3.28351
DRC3 dynein regulatory complex subunit 3 3.28351
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 3.28351
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic 3.28351
NDP Norrie disease (pseudoglioma) 3.28351
SYT15 synaptotagmin XV 3.28351
LTB lymphotoxin beta (TNF superfamily, member 3) 3.28351
BEST3 bestrophin 3 3.28351
GDF5 growth differentiation factor 5 3.28351
C7 complement component 7 3.28351
SMPX small muscle protein, X-linked 3.28351
SPEM1 spermatid maturation 1 3.28351
SMIM35 small integral membrane protein 35 3.28351
PEAK3 PEAK family member 3 3.28351
ANGPTL8 angiopoietin like 8 3.28351
CCDC9B coiled-coil domain containing 9B 3.28351
UNC93A unc-93 homolog A (C. elegans) 3.28351
PROP1 PROP paired-like homeobox 1 3.28351
EXOC1L exocyst complex component 1 like 3.28351
GPX6 glutathione peroxidase 6 3.28351
C9 complement component 9 3.28351
CNTFR ciliary neurotrophic factor receptor 3.28351
GZMM granzyme M (lymphocyte met-ase 1) 3.28351
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 3.28351
TMPRSS11A transmembrane protease, serine 11A 3.28351
CST11 cystatin 11 3.28351
COL20A1 collagen, type XX, alpha 1 3.28351
OR2A1 olfactory receptor, family 2, subfamily A, member 1 3.28351
CLEC12A C-type lectin domain family 12, member A 3.28351
DNAJC5B DnaJ (Hsp40) homolog, subfamily C, member 5 beta 3.28351
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 3.28351
SPATA31H1 SPATA31 subfamily H member 1 3.28351
FER1L6 fer-1-like family member 6 3.28351
ADGRG1 adhesion G protein-coupled receptor G1 3.28351
OR11A1 olfactory receptor, family 11, subfamily A, member 1 3.28351
VSX2 visual system homeobox 2 3.28351
CLDN9 claudin 9 3.28351
PVRIG poliovirus receptor related immunoglobulin domain containing 3.28351
FFAR2 free fatty acid receptor 2 3.28351
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.28351
TAS2R5 taste receptor, type 2, member 5 3.28351
FBXL8 F-box and leucine-rich repeat protein 8 3.28351
IRGM immunity-related GTPase family, M 3.28351
COL6A5 collagen, type VI, alpha 5 3.28351
NOG noggin 3.28351
ZC3H11D zinc finger CCCH-type containing 11D 3.28351
ZNF132 zinc finger protein 132 3.28351
SIDT1 SID1 transmembrane family, member 1 3.28351
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 3.28351
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 3.28351
SMIM22 small integral membrane protein 22 3.28351
CLDN34 claudin 34 3.28351
CRYBA1 crystallin, beta A1 3.28351
F2RL2 coagulation factor II (thrombin) receptor-like 2 3.28351
EPGN epithelial mitogen 3.28351
EPHA5 EPH receptor A5 3.28351
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.28351
PRSS55 protease, serine, 55 3.28351
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 3.28351
EFCAB8 EF-hand calcium binding domain 8 3.28351
HOPX HOP homeobox 3.28351
APOC2 apolipoprotein C-II 3.28351
SMR3B submaxillary gland androgen regulated protein 3B 3.28351
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 3.28351
SPINK9 serine peptidase inhibitor, Kazal type 9 3.28351
SERINC4 serine incorporator 4 3.28351
PCDHGA2 protocadherin gamma subfamily A, 2 3.28351
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.28351
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.28351
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1 3.28351
EMX2 empty spiracles homeobox 2 3.28351
GOLGA8R golgin A8 family, member R 3.28351
NANOGNB NANOG neighbor homeobox 3.28351
ANKRD63 ankyrin repeat domain 63 3.28351
OR9A4 olfactory receptor, family 9, subfamily A, member 4 3.28351
AQP6 aquaporin 6, kidney specific 3.28351
CALML6 calmodulin-like 6 3.28351
AMIGO3 adhesion molecule with Ig-like domain 3 3.28351
CD84 CD84 molecule 3.28351
RGS4 regulator of G-protein signaling 4 3.28351
LY6G5C lymphocyte antigen 6 complex, locus G5C 3.28351
POU4F1 POU class 4 homeobox 1 3.28351
FCAR Fc fragment of IgA receptor 3.28351
ADRA1B adrenoceptor alpha 1B 3.28351
TGM4 transglutaminase 4 3.28351
TGM6 transglutaminase 6 3.28351
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 3.28351
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 3.28351
WNT2 wingless-type MMTV integration site family member 2 3.28351
BANF2 barrier to autointegration factor 2 3.28351
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 3.28351
PENK proenkephalin 3.28351
POTEJ POTE ankyrin domain family, member J 3.28351
NUTM2D NUT family member 2D 3.28351
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 3.28351
KCNK7 potassium channel, two pore domain subfamily K, member 7 3.28351
VTCN1 V-set domain containing T cell activation inhibitor 1 3.28351
MC5R melanocortin 5 receptor 3.28351
NT5DC4 5'-nucleotidase domain containing 4 3.28351
ECM1 extracellular matrix protein 1 3.28351
PATE2 prostate and testis expressed 2 3.28351
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 3.23029
GHRL ghrelin/obestatin prepropeptide 3.23029
LHX6 LIM homeobox 6 3.23029
ACD adrenocortical dysplasia homolog (mouse) 3.17764
PLAC9 placenta-specific 9 3.17764
CCDC126 coiled-coil domain containing 126 3.17764
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 3.15587
MKNK1 MAP kinase interacting serine/threonine kinase 1 2.97416
TBL1X transducin (beta)-like 1X-linked 2.87935
PON3 paraoxonase 3 2.86296
NPTN neuroplastin 2.78254
LPIN1 lipin 1 2.7376
SNAP91 synaptosomal-associated protein, 91kDa 2.55327
ZNF619 zinc finger protein 619 2.49762
IFFO1 intermediate filament family orphan 1 2.48444
ARHGAP6 Rho GTPase activating protein 6 2.45665
SNX9 sorting nexin 9 2.38327
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 2.37789
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.36782
TCEAL9 transcription elongation factor A like 9 2.36574
TTC29 tetratricopeptide repeat domain 29 2.35072
SMIM47 small integral membrane protein 47 2.35072
FNDC8 fibronectin type III domain containing 8 2.35072
TMEM255A transmembrane protein 255A 2.35072
AP1G2 adaptor-related protein complex 1, gamma 2 subunit 2.32487
ZNF804B zinc finger protein 804B 2.30153
APP-DT APP divergent transcript 2.28429
ZDHHC22 zinc finger, DHHC-type containing 22 2.2757
ARHGAP18 Rho GTPase activating protein 18 2.26699
LTN1 listerin E3 ubiquitin protein ligase 1 2.24632
FMN1 formin 1 2.24612
TRPV4 transient receptor potential cation channel, subfamily V, member 4 2.22552
NUDC nudC nuclear distribution protein 2.22526
SLC43A3 solute carrier family 43, member 3 2.22526
SMYD3 SET and MYND domain containing 3 2.20801
TRERF1 transcriptional regulating factor 1 2.20801
TPM1 tropomyosin 1 (alpha) 2.20801
TMEM141 transmembrane protein 141 2.20663
ERCC6 excision repair cross-complementation group 6 2.20663
DHRSX dehydrogenase/reductase (SDR family) X-linked 2.16586
FBXL15 F-box and leucine-rich repeat protein 15 2.16586
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 2.16581
RAD1 RAD1 checkpoint DNA exonuclease 2.1654
HMCN2 hemicentin 2 2.15708
PIP4P2 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2 2.15571
ADGRA3 adhesion G protein-coupled receptor A3 2.15152
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.15061
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 2.1477
TDG thymine-DNA glycosylase 2.13678
TMED5 transmembrane emp24 protein transport domain containing 5 2.11599
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 2.10449
UPRT uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) 2.07406
TRIM24 tripartite motif containing 24 2.06779
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 2.06779
NOL8 nucleolar protein 8 2.03526
ZBTB8B zinc finger and BTB domain containing 8B 2.03526
E2F8 E2F transcription factor 8 2.03526
NFS1 NFS1 cysteine desulfurase 2.02061
C1D C1D nuclear receptor corepressor 2.02061
ZNF587B zinc finger protein 587B 2.00621
BRCC3 BRCA1/BRCA2-containing complex, subunit 3 2.00557
PHB1 prohibitin 1 2.00263

decreased expression

Symbol Name Standardized Value
GP1BA glycoprotein Ib (platelet), alpha polypeptide -3.34438
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -3.28351
KRT8 keratin 8, type II -3.28351
PRB3 proline-rich protein BstNI subfamily 3 -3.28351
FAM89A family with sequence similarity 89, member A -3.28351
LCN12 lipocalin 12 -3.28351
TWIST2 twist family bHLH transcription factor 2 -3.20652
ITIH6 inter-alpha-trypsin inhibitor heavy chain family, member 6 -3.17764
MLANA melan-A -3.17764
INHBC inhibin, beta C -3.17764
FXYD3 FXYD domain containing ion transport regulator 3 -3.17764
STARD6 StAR-related lipid transfer (START) domain containing 6 -3.17764
LPA lipoprotein, Lp(a) -3.17764
MEIOB meiosis specific with OB domains -3.17764
TMEM213 transmembrane protein 213 -3.17764
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) -3.17764
GYS2 glycogen synthase 2 (liver) -3.17764
SCG2 secretogranin II -3.17764
SCARA5 scavenger receptor class A, member 5 -3.17764
SPINK1 serine peptidase inhibitor, Kazal type 1 -3.17764
NANOS3 nanos homolog 3 (Drosophila) -3.17764
FAM86B2 family with sequence similarity 86, member B2 -3.17764
IRF8 interferon regulatory factor 8 -3.17764
MIA melanoma inhibitory activity -3.17764
SLC44A4 solute carrier family 44, member 4 -3.17764
PRR4 proline rich 4 (lacrimal) -3.17764
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) -3.17764
SYTL4 synaptotagmin-like 4 -3.17764
FSTL3 follistatin-like 3 (secreted glycoprotein) -3.17764
UPK3B uroplakin 3B -3.17764
KASH5 KASH domain containing 5 -3.17764
VN1R1 vomeronasal 1 receptor 1 -3.17764
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 -3.17764
ZMYND12 zinc finger, MYND-type containing 12 -3.17764
ANO3 anoctamin 3 -3.17764
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -3.17764
CD200R1 CD200 receptor 1 -3.17764
SUN3 Sad1 and UNC84 domain containing 3 -3.17764
ADAM2 ADAM metallopeptidase domain 2 -3.17764
IMPG2 interphotoreceptor matrix proteoglycan 2 -3.17764
TRPM1 transient receptor potential cation channel, subfamily M, member 1 -3.17764
C22ORF42 chromosome 22 open reading frame 42 -3.17764
ZNF506 zinc finger protein 506 -3.12948
BCL2L13 BCL2-like 13 (apoptosis facilitator) -3.09518
AGER advanced glycosylation end product-specific receptor -3.05892
NLRP2 NLR family, pyrin domain containing 2 -3.05892
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 -3.00995
ARMH3 armadillo like helical domain containing 3 -2.98624
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -2.82977
DMAP1 DNA methyltransferase 1 associated protein 1 -2.82977
AGA aspartylglucosaminidase -2.82977
FAM110D family with sequence similarity 110, member D -2.68174
TMEM102 transmembrane protein 102 -2.68174
SNX27 sorting nexin family member 27 -2.65787
RPUSD1 RNA pseudouridylate synthase domain containing 1 -2.55499
RASGRP4 RAS guanyl releasing protein 4 -2.50167
CD70 CD70 molecule -2.48096
RNASEH2C ribonuclease H2, subunit C -2.46823
MRPL23 mitochondrial ribosomal protein L23 -2.42051
HNRNPA1L3 heterogeneous nuclear ribonucleoprotein A1 like 3 -2.41235
APCDD1L adenomatosis polyposis coli down-regulated 1-like -2.41174
CCDC194 coiled-coil domain containing 194 -2.38354
GPX3 glutathione peroxidase 3 -2.36742
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -2.36274
SETD4 SET domain containing 4 -2.35072
TBC1D25 TBC1 domain family, member 25 -2.34139
CASR calcium-sensing receptor -2.33755
ATG2B autophagy related 2B -2.33393
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 -2.30606
TWF2 twinfilin actin binding protein 2 -2.27706
PRRT1 proline-rich transmembrane protein 1 -2.26853
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 -2.26853
DEXI Dexi homolog (mouse) -2.26853
CCDC177 coiled-coil domain containing 177 -2.26853
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -2.26699
SPATA20 spermatogenesis associated 20 -2.25685
SIRT4 sirtuin 4 -2.23425
AURKAIP1 aurora kinase A interacting protein 1 -2.2325
HYCC2 hyccin PI4KA lipid kinase complex subunit 2 -2.22526
FOXK2 forkhead box K2 -2.20801
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 -2.20643
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.20643
IAPP islet amyloid polypeptide -2.20643
CDC20 cell division cycle 20 -2.17182
RNFT1 ring finger protein, transmembrane 1 -2.16586
COMMD9 COMM domain containing 9 -2.16586
MSMO1 methylsterol monooxygenase 1 -2.1477
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.14491
CFAP69 cilia and flagella associated protein 69 -2.14479
AKR1C3 aldo-keto reductase family 1, member C3 -2.13854
TAMALIN trafficking regulator and scaffold protein tamalin -2.12676
RPL31 ribosomal protein L31 -2.11425
SLC39A3 solute carrier family 39 (zinc transporter), member 3 -2.10193
CDK1 cyclin-dependent kinase 1 -2.09644
ZNF613 zinc finger protein 613 -2.06841
SIRPA signal-regulatory protein alpha -2.03526
CCDC196 coiled-coil domain containing 196 -2.03526
NAP1L5 nucleosome assembly protein 1-like 5 -2.03526
BTN3A3 butyrophilin, subfamily 3, member A3 -2.03526
CRYGS crystallin, gamma S -2.03526
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) -2.03526
ARMC8 armadillo repeat containing 8 -2.03482
FBXO44 F-box protein 44 -2.00621
SNUPN snurportin 1 -2.00238