GATA3 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description GATA binding protein 3|This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009] (NCBI Entrez Gene Database, 2625)
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Genes

286 genes differentially expressed following the GATA3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
GPR17 G protein-coupled receptor 17 4.55676
RGPD3 RANBP2-like and GRIP domain containing 3 4.55676
MS4A18 membrane-spanning 4-domains, subfamily A, member 18 4.55676
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 4.55676
F7 coagulation factor VII (serum prothrombin conversion accelerator) 4.55676
NRROS negative regulator of reactive oxygen species 4.55676
PTGFR prostaglandin F receptor (FP) 4.55676
ALPK2 alpha-kinase 2 4.55676
SSTR3 somatostatin receptor 3 4.55676
SSTR5 somatostatin receptor 5 4.55676
SLC30A4 solute carrier family 30 (zinc transporter), member 4 4.55676
OLFM4 olfactomedin 4 4.55676
XCL1 chemokine (C motif) ligand 1 4.55676
MANSC4 MANSC domain containing 4 4.55676
SLC15A5 solute carrier family 15, member 5 4.55676
FOXR1 forkhead box R1 4.55676
GJB3 gap junction protein, beta 3, 31kDa 4.55676
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 4.55676
MUC20 mucin 20, cell surface associated 4.55676
KRT72 keratin 72, type II 4.55676
B3GNT8 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 4.55676
AOC1 amine oxidase, copper containing 1 4.55676
NLRP9 NLR family, pyrin domain containing 9 4.55676
NEUROD4 neuronal differentiation 4 4.55676
IRX1 iroquois homeobox 1 4.55676
GHRH growth hormone releasing hormone 4.55676
ZC2HC1B zinc finger, C2HC-type containing 1B 4.55676
FXYD3 FXYD domain containing ion transport regulator 3 4.55676
HRG histidine-rich glycoprotein 4.55676
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 4.55676
PODN podocan 4.55676
OR6J1 olfactory receptor, family 6, subfamily J, member 1 (gene/pseudogene) 4.55676
LOC102724877 uncharacterized LOC102724877 4.55676
KIAA1755 KIAA1755 4.55676
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 4.55676
SLC22A9 solute carrier family 22 (organic anion transporter), member 9 4.55676
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 4.55676
PRDM12 PR domain containing 12 4.55676
ZNF560 zinc finger protein 560 4.55676
CCL5 chemokine (C-C motif) ligand 5 4.55676
MUC6 mucin 6, oligomeric mucus/gel-forming 4.55676
SAMD11 sterile alpha motif domain containing 11 4.55676
LTA lymphotoxin alpha 4.55676
GATA1 GATA binding protein 1 (globin transcription factor 1) 4.55676
C15ORF62 chromosome 15 open reading frame 62 4.55676
ZNF705A zinc finger protein 705A 4.55676
C10ORF53 chromosome 10 open reading frame 53 4.55676
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) 4.55676
SPEM1 spermatid maturation 1 4.55676
MGAT4D MGAT4 family, member D 4.55676
GBP7 guanylate binding protein 7 4.55676
HAO2 hydroxyacid oxidase 2 (long chain) 4.55676
H3-5 H3.5 histone 4.55676
CCDC197 coiled-coil domain containing 197 4.55676
CPHXL cytoplasmic polyadenylated homeobox like 4.55676
CIBAR2 CBY1 interacting BAR domain containing 2 4.55676
SMIM31 small integral membrane protein 31 4.55676
H4C14 H4 clustered histone 14 4.55676
S100G S100 calcium binding protein G 4.55676
SH3TC1 SH3 domain and tetratricopeptide repeats 1 4.55676
TFEC transcription factor EC 4.55676
SPATA31A6 SPATA31 subfamily A, member 6 4.55676
IGFL3 IGF-like family member 3 4.55676
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 4.55676
GPR52 G protein-coupled receptor 52 4.55676
IYD iodotyrosine deiodinase 4.55676
DRC5 dynein regulatory complex subunit 5 4.55676
FAM167B family with sequence similarity 167, member B 4.55676
NAPSA napsin A aspartic peptidase 4.55676
SRMS src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites 4.55676
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 4.55676
COL20A1 collagen, type XX, alpha 1 4.55676
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound 4.55676
SPDYE6 speedy/RINGO cell cycle regulator family member E6 4.55676
PVRIG poliovirus receptor related immunoglobulin domain containing 4.55676
ATP13A5 ATPase type 13A5 4.55676
VIT vitrin 4.55676
DMBX1 diencephalon/mesencephalon homeobox 1 4.55676
CTXND1 cortexin domain containing 1 4.55676
C6ORF163 chromosome 6 open reading frame 163 4.55676
SMIM22 small integral membrane protein 22 4.55676
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa 4.55676
CDH19 cadherin 19, type 2 4.55676
APOC2 apolipoprotein C-II 4.55676
KRT15 keratin 15, type I 4.55676
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 4.55676
IFNL4 interferon, lambda 4 (gene/pseudogene) 4.55676
MUC13 mucin 13, cell surface associated 4.55676
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 4.55676
OR52L1 olfactory receptor, family 52, subfamily L, member 1 4.55676
CIDEA cell death-inducing DFFA-like effector a 4.55676
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 4.55676
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 4.55676
POF1B premature ovarian failure, 1B 4.55676
ACCSL 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)-like 4.55676
ARR3 arrestin 3, retinal (X-arrestin) 4.55676
TCEA3 transcription elongation factor A (SII), 3 4.55676
SPATA31E1 SPATA31 subfamily E, member 1 4.55676
SHOX2 short stature homeobox 2 4.55676
FNDC9 fibronectin type III domain containing 9 4.55676
FNDC1 fibronectin type III domain containing 1 4.55676
SMIM23 small integral membrane protein 23 4.55676
DUOX2 dual oxidase 2 4.55676
ZNF366 zinc finger protein 366 4.55676
DNTT DNA nucleotidylexotransferase 4.55676
APOL1 apolipoprotein L, 1 4.55676
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 4.55676
HMGB4 high mobility group box 4 4.55676
KCNH3 potassium channel, voltage gated eag related subfamily H, member 3 4.55676
POU4F1 POU class 4 homeobox 1 4.55676
TMPRSS13 transmembrane protease, serine 13 4.55676
CLEC18B C-type lectin domain family 18, member B 4.55676
CCDC78 coiled-coil domain containing 78 4.55676
GPRC5D G protein-coupled receptor, class C, group 5, member D 4.55676
GOLGA8O golgin A8 family, member O 4.55676
GOLGA8R golgin A8 family, member R 4.55676
TRPM5 transient receptor potential cation channel, subfamily M, member 5 4.55676
TF transferrin 4.55676
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 4.55676
ISLR immunoglobulin superfamily containing leucine-rich repeat 4.55676
MORN5 MORN repeat containing 5 4.55676
ZC3H11D zinc finger CCCH-type containing 11D 4.55676
SIRPG signal-regulatory protein gamma 4.55676
PENK proenkephalin 4.55676
PATE2 prostate and testis expressed 2 4.55676
ZNF596 zinc finger protein 596 4.55676
AZU1 azurocidin 1 4.53682
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa 4.53682
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 4.1741
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 3.80529
CFAP61 cilia and flagella associated protein 61 3.62321
ODAD1 outer dynein arm docking complex subunit 1 3.62321
HUS1B HUS1 checkpoint homolog b (S. pombe) 3.62321
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 3.62321
PANO1 proapoptotic nucleolar protein 1 3.62321
LRRTM2 leucine rich repeat transmembrane neuronal 2 3.62321
ASB14 ankyrin repeat and SOCS box containing 14 3.62321
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3 3.62321
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 3.62321
POLE polymerase (DNA directed), epsilon, catalytic subunit 3.62169
YJEFN3 YjeF N-terminal domain containing 3 3.49105
TMEM126A transmembrane protein 126A 3.35237
TRIQK triple QxxK/R motif containing 3.32205
OCIAD2 OCIA domain containing 2 3.26342
LRRC8E leucine rich repeat containing 8 family, member E 3.13838
ACAA1 acetyl-CoA acyltransferase 1 2.92503
BATF3 basic leucine zipper transcription factor, ATF-like 3 2.82999
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 2.82999
LRRC34 leucine rich repeat containing 34 2.81511
OR2A7 olfactory receptor, family 2, subfamily A, member 7 2.78651
CCDC51 coiled-coil domain containing 51 2.71682
CPQ carboxypeptidase Q 2.7096
TPM4 tropomyosin 4 2.65003
ARMCX4 armadillo repeat containing, X-linked 4 2.64286
CTSC cathepsin C 2.59132
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 2.5395
SLTM SAFB-like, transcription modulator 2.53717
IFI30 interferon, gamma-inducible protein 30 2.47721
MBTPS2 membrane-bound transcription factor peptidase, site 2 2.40326
PCDHA12 protocadherin alpha 12 2.34566
PCIF1 PDX1 C-terminal inhibiting factor 1 2.32339
ZNF749 zinc finger protein 749 2.30398
OTUD4 OTU deubiquitinase 4 2.2909
ZNF404 zinc finger protein 404 2.28318
CLDN10 claudin 10 2.28318
FASTKD2 FAST kinase domains 2 2.27377
PFKM phosphofructokinase, muscle 2.24449
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 2.23853
GTSF1 gametocyte specific factor 1 2.23374
GGACT gamma-glutamylamine cyclotransferase 2.22642
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 2.22642
DPPA3 developmental pluripotency associated 3 2.21672
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 2.21672
TGM7 transglutaminase 7 2.21672
MATCAP1 microtubule associated tyrosine carboxypeptidase 1 2.20841
RFC5 replication factor C (activator 1) 5, 36.5kDa 2.20696
QRICH1 glutamine-rich 1 2.17985
LOC105378220 macrophage receptor MARCO-like 2.17717
CHMP4B charged multivesicular body protein 4B 2.15972
LSM1 LSM1, U6 small nuclear RNA associated 2.14975
DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 2.13633
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 2.119
S1PR2 sphingosine-1-phosphate receptor 2 2.11042
NKAIN1 Na+/K+ transporting ATPase interacting 1 2.10596
FRAT2 frequently rearranged in advanced T-cell lymphomas 2 2.09426
OTX2 orthodenticle homeobox 2 2.08236
TADA2A transcriptional adaptor 2A 2.081
NLGN2 neuroligin 2 2.0746
TPMT thiopurine S-methyltransferase 2.07052
PEX11A peroxisomal biogenesis factor 11 alpha 2.07052
WNT3 wingless-type MMTV integration site family, member 3 2.06323
CNN3 calponin 3, acidic 2.05954
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae) 2.05954
ATF7IP2 activating transcription factor 7 interacting protein 2 2.05954
RNF103 ring finger protein 103 2.05117
NASP nuclear autoantigenic sperm protein (histone-binding) 2.05117
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase 2.05117
FADS3 fatty acid desaturase 3 2.04608
TNS3 tensin 3 2.03837
LNP1 leukemia NUP98 fusion partner 1 2.02903
NPTX2 neuronal pentraxin II 2.02903
RPA2 replication protein A2, 32kDa 2.02356
SFMBT1 Scm-like with four mbt domains 1 2.00477
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 2.00381
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 2.00283

decreased expression

Symbol Name Standardized Value
ZEB2 zinc finger E-box binding homeobox 2 -4.55676
SPDYE2B speedy/RINGO cell cycle regulator family member E2B -4.55676
NME8 NME/NM23 family member 8 -4.55676
TBXA2R thromboxane A2 receptor -4.48437
CNTNAP4 contactin associated protein-like 4 -4.48437
ASB12 ankyrin repeat and SOCS box containing 12 -4.48437
SERINC4 serine incorporator 4 -4.48437
IL21R interleukin 21 receptor -4.48437
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 -4.48437
CXCR4 chemokine (C-X-C motif) receptor 4 -4.48437
HSD17B13 hydroxysteroid (17-beta) dehydrogenase 13 -4.48437
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 -4.48437
APOH apolipoprotein H (beta-2-glycoprotein I) -4.48437
ADIRF adipogenesis regulatory factor -4.48437
NPAS4 neuronal PAS domain protein 4 -4.48437
CRB1 crumbs family member 1, photoreceptor morphogenesis associated -4.48437
ARGFX arginine-fifty homeobox -4.48437
FAIM2 Fas apoptotic inhibitory molecule 2 -4.48437
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) -4.48437
SLC25A34 solute carrier family 25, member 34 -4.48437
KLB klotho beta -4.48437
FLRT3 fibronectin leucine rich transmembrane protein 3 -4.48437
IDI2 isopentenyl-diphosphate delta isomerase 2 -4.48437
FAM43B family with sequence similarity 43, member B -4.48437
TMEM225B transmembrane protein 225B -4.48437
AKAP14 A kinase (PRKA) anchor protein 14 -4.48437
RELN reelin -4.48437
CLC Charcot-Leyden crystal galectin -4.4125
FUT9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) -4.36576
H2AC13 H2A clustered histone 13 -3.98707
TMTC4 transmembrane and tetratricopeptide repeat containing 4 -3.85697
RAD50 RAD50 homolog (S. cerevisiae) -3.61678
KCTD16 potassium channel tetramerization domain containing 16 -3.54565
KCTD19 potassium channel tetramerization domain containing 19 -3.32938
FAM229A family with sequence similarity 229, member A -3.32938
PCDHA5 protocadherin alpha 5 -3.32938
PCDHA13 protocadherin alpha 13 -3.32938
GK glycerol kinase -2.96112
NDC80 NDC80 kinetochore complex component -2.9111
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 -2.78955
C1ORF202 chromosome 1 open reading frame 202 -2.78699
PBX2 pre-B-cell leukemia homeobox 2 -2.78143
MROH9 maestro heat-like repeat family member 9 -2.77723
WWOX WW domain containing oxidoreductase -2.75709
MRO maestro -2.73376
GCNT7 glucosaminyl (N-acetyl) transferase family member 7 -2.73376
CDC14A cell division cycle 14A -2.73283
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -2.72539
FOXM1 forkhead box M1 -2.69879
FCRL5 Fc receptor-like 5 -2.69044
ZNF233 zinc finger protein 233 -2.69044
ETAA1 Ewing tumor-associated antigen 1 -2.67931
VWCE von Willebrand factor C and EGF domains -2.64286
ANKRD39 ankyrin repeat domain 39 -2.5058
NREP neuronal regeneration related protein -2.50043
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 -2.49463
KLHL2 kelch-like family member 2 -2.41689
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 -2.33513
DENND5B DENN/MADD domain containing 5B -2.32339
TRAPPC8 trafficking protein particle complex 8 -2.29163
SYDE2 synapse defective 1, Rho GTPase, homolog 2 (C. elegans) -2.28318
GLI4 GLI family zinc finger 4 -2.28225
SMAD2 SMAD family member 2 -2.27377
ERMARD ER membrane-associated RNA degradation -2.21672
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -2.17717
COL4A4 collagen, type IV, alpha 4 -2.17647
FBXO41 F-box protein 41 -2.16968
PDHX pyruvate dehydrogenase complex, component X -2.16459
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 -2.16455
UPK1A uroplakin 1A -2.13633
VAMP5 vesicle-associated membrane protein 5 -2.12728
MOGAT3 monoacylglycerol O-acyltransferase 3 -2.12459
CLCN4 chloride channel, voltage-sensitive 4 -2.119
MYLK4 myosin light chain kinase family, member 4 -2.10837
SH3BGR SH3 domain binding glutamate-rich protein -2.09636
AKAP12 A kinase (PRKA) anchor protein 12 -2.08952
NPIPA1 nuclear pore complex interacting protein family, member A1 -2.07052
FAM13C family with sequence similarity 13, member C -2.07052
AHCYL2 adenosylhomocysteinase-like 2 -2.06914
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q -2.05117
RAD51B RAD51 paralog B -2.05117