GATA4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description GATA binding protein 4|This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] (NCBI Entrez Gene Database, 2626)
External Link http://www.ncbi.nlm.nih.gov/gene/2626
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Genes

30 interacting proteins for GATA4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ALX4 ALX homeobox 4
CRIP2 cysteine-rich protein 2
EP300 E1A binding protein p300
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FOS FBJ murine osteosarcoma viral oncogene homolog
HAND2 heart and neural crest derivatives expressed 2
HDAC2 histone deacetylase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
JARID2 jumonji, AT rich interactive domain 2
KDM6A lysine (K)-specific demethylase 6A
KLF13 Kruppel-like factor 13
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MDC1 mediator of DNA-damage checkpoint 1
MED1 mediator complex subunit 1
MEF2C myocyte enhancer factor 2C
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NKX2-5 NK2 homeobox 5
NR5A1 nuclear receptor subfamily 5, group A, member 1
PIAS1 protein inhibitor of activated STAT, 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
SP1 Sp1 transcription factor
SRF serum response factor (c-fos serum response element-binding transcription factor)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
TBX5 T-box 5
ZBTB3 zinc finger and BTB domain containing 3
ZFPM2 zinc finger protein, FOG family member 2