GBX2 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description gastrulation brain homeobox 2| (NCBI Entrez Gene Database, 2637)
Similar Terms
Downloads & Tools

Genes

316 genes differentially expressed following the GBX2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
KLK13 kallikrein-related peptidase 13 3.25721
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 3.25721
FLNC filamin C, gamma 3.25721
B3GNT9 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 3.25721
ASPG asparaginase 3.25721
FOXN4 forkhead box N4 3.25721
CASP4 caspase 4, apoptosis-related cysteine peptidase 3.25721
H1-6 H1.6 linker histone, cluster member 3.25721
TMEM176A transmembrane protein 176A 3.25721
FAM167B family with sequence similarity 167, member B 3.25721
IFIT1B interferon-induced protein with tetratricopeptide repeats 1B 3.25721
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 3.25721
GJD3 gap junction protein, delta 3, 31.9kDa 3.25721
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 3.25721
OTOF otoferlin 3.25721
CCL25 chemokine (C-C motif) ligand 25 3.25721
LRRC43 leucine rich repeat containing 43 3.25721
BRDT bromodomain, testis-specific 3.25721
SPAG6 sperm associated antigen 6 3.25721
GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 3.25721
ICAM5 intercellular adhesion molecule 5, telencephalin 3.25721
SRPK3 SRSF protein kinase 3 3.22331
C9ORF152 chromosome 9 open reading frame 152 3.22331
ADRB1 adrenoceptor beta 1 3.22331
MS4A15 membrane-spanning 4-domains, subfamily A, member 15 3.22331
C11ORF86 chromosome 11 open reading frame 86 3.22331
BSX brain-specific homeobox 3.22331
TAL2 T-cell acute lymphocytic leukemia 2 3.22331
RGL4 ral guanine nucleotide dissociation stimulator-like 4 3.22331
FHL5 four and a half LIM domains 5 3.22331
MEIKIN meiotic kinetochore factor 3.22331
SOWAHB sosondowah ankyrin repeat domain family member B 3.22331
MYL4 myosin, light chain 4, alkali; atrial, embryonic 3.22331
GBP4 guanylate binding protein 4 3.22331
GBP5 guanylate binding protein 5 3.22331
YIPF7 Yip1 domain family, member 7 3.22331
OR4D9 olfactory receptor, family 4, subfamily D, member 9 3.22331
ASGR2 asialoglycoprotein receptor 2 3.22331
ROPN1L rhophilin associated tail protein 1-like 3.22331
LGALS2 lectin, galactoside-binding, soluble, 2 3.22331
JCHAIN joining chain of multimeric IgA and IgM 3.22331
TAS2R13 taste receptor, type 2, member 13 3.22331
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 3.22331
HTRA4 HtrA serine peptidase 4 3.22331
TREML2 triggering receptor expressed on myeloid cells-like 2 3.22331
MISP mitotic spindle positioning 3.22331
WNT8B wingless-type MMTV integration site family, member 8B 3.22331
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 3.22331
PRR29 proline rich 29 3.22331
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 3.22331
GZMK granzyme K (granzyme 3; tryptase II) 3.22331
PRB2 proline-rich protein BstNI subfamily 2 3.22331
PCDHA5 protocadherin alpha 5 3.22331
GTSF1 gametocyte specific factor 1 3.22331
ACKR5 atypical chemokine receptor 5 3.22331
LTB lymphotoxin beta (TNF superfamily, member 3) 3.22331
SCARA5 scavenger receptor class A, member 5 3.22331
LAPTM5 lysosomal protein transmembrane 5 3.22331
ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 3.22331
PCDHB10 protocadherin beta 10 3.22331
CCR6 chemokine (C-C motif) receptor 6 3.22331
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 3.22331
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 3.22331
IL5 interleukin 5 3.22331
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 3.22331
TMEM235 transmembrane protein 235 3.22331
PIWIL3 piwi-like RNA-mediated gene silencing 3 3.22331
OR51B2 olfactory receptor, family 51, subfamily B, member 2 (gene/pseudogene) 3.22331
C3ORF80 chromosome 3 open reading frame 80 3.22331
STKLD1 serine/threonine kinase-like domain containing 1 3.22331
LURAP1L leucine rich adaptor protein 1-like 3.22331
ALB albumin 3.22331
UMOD uromodulin 3.22331
C8ORF48 chromosome 8 open reading frame 48 3.22331
CXORF65 chromosome X open reading frame 65 3.22331
DUSP10 dual specificity phosphatase 10 3.22331
DSG3 desmoglein 3 3.22331
PAX5 paired box 5 3.22331
GC group-specific component (vitamin D binding protein) 3.22331
DMRTC1B DMRT-like family C1B 3.22331
CCNB3 cyclin B3 3.22331
DOK7 docking protein 7 3.22331
CNTN6 contactin 6 3.22331
FGD2 FYVE, RhoGEF and PH domain containing 2 3.22331
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 3.22331
RNF183 ring finger protein 183 3.22331
SLC46A2 solute carrier family 46, member 2 3.22331
ANKRD22 ankyrin repeat domain 22 3.22331
OR51A7 olfactory receptor, family 51, subfamily A, member 7 3.22331
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 3.22331
XCL2 chemokine (C motif) ligand 2 3.22331
LVRN laeverin 3.22331
OR52N2 olfactory receptor, family 52, subfamily N, member 2 3.22331
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 3.22331
SERINC4 serine incorporator 4 3.22331
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 3.22331
TRIM50 tripartite motif containing 50 3.22331
MAP3K4-AS1 MAP3K4 antisense RNA 1 3.22331
LBX2 ladybird homeobox 2 3.22331
BCO1 beta-carotene oxygenase 1 3.22331
ISL1 ISL LIM homeobox 1 3.22331
CALHM1 calcium homeostasis modulator 1 3.22331
KLF4 Kruppel-like factor 4 (gut) 3.22331
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 3.22331
ZNF541 zinc finger protein 541 3.22331
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 3.22331
MEIOSIN meiosis initiator 3.22331
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 3.22331
GLOD5 glyoxalase domain containing 5 3.22331
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 3.22331
MAP3K19 mitogen-activated protein kinase kinase kinase 19 3.22331
IL1A interleukin 1, alpha 3.22331
LRRK2 leucine-rich repeat kinase 2 3.22331
EFCAB12 EF-hand calcium binding domain 12 3.22331
KIF1C-AS1 KIF1C antisense RNA 1 3.22331
LINC02268 long intergenic non-protein coding RNA 2268 3.22331
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 3.22331
PCDHAC2 protocadherin alpha subfamily C, 2 3.22331
LAMB3 laminin, beta 3 3.22331
ZC3H11C zinc finger CCCH-type containing 11C 3.22331
ETV3L ets variant 3-like 3.22331
LGALS12 lectin, galactoside-binding, soluble, 12 3.22331
UBXN10 UBX domain protein 10 3.22331
ITGAD integrin, alpha D 3.22331
CD200R1 CD200 receptor 1 3.22331
CFI complement factor I 3.22331
SCNN1D sodium channel, non voltage gated 1 delta subunit 3.22331
IRF2-DT IRF2 divergent transcript 3.22331
OTOP2 otopetrin 2 3.22331
ZIM2 zinc finger, imprinted 2 3.22331
DND1 DND microRNA-mediated repression inhibitor 1 3.22331
NIM1K NIM1 serine/threonine protein kinase 3.22331
GAGE10 G antigen 10 3.22331
ALOX15B arachidonate 15-lipoxygenase, type B 3.22331
GCM1 glial cells missing homolog 1 (Drosophila) 3.22331
PARP15 poly (ADP-ribose) polymerase family, member 15 3.22331
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 3.22331
C10ORF90 chromosome 10 open reading frame 90 3.22331
TMPRSS15 transmembrane protease, serine 15 3.22331
KCTD4 potassium channel tetramerization domain containing 4 3.22331
ACSM2A acyl-CoA synthetase medium-chain family member 2A 3.22331
OXER1 oxoeicosanoid (OXE) receptor 1 3.22331
MYOZ2 myozenin 2 3.22331
POPDC2 popeye domain containing 2 3.22331
NRGN neurogranin (protein kinase C substrate, RC3) 3.22331
FGF7 fibroblast growth factor 7 3.22331
HAO2 hydroxyacid oxidase 2 (long chain) 3.22331
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 3.22331
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 3.22331
EPHB3 EPH receptor B3 3.22331
LST1 leukocyte specific transcript 1 3.22331
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 3.22331
CPHXL2 cytoplasmic polyadenylated homeobox like 2 3.22331
NSG2 neuronal vesicle trafficking associated 2 3.22331
FBXO39 F-box protein 39 3.22331
TIGIT T cell immunoreceptor with Ig and ITIM domains 3.22331
RSAD2 radical S-adenosyl methionine domain containing 2 3.22331
CMTM2 CKLF-like MARVEL transmembrane domain containing 2 3.22331
CYBB cytochrome b-245, beta polypeptide 3.22331
HSF5 heat shock transcription factor family member 5 3.22331
KCNK3 potassium channel, two pore domain subfamily K, member 3 3.22331
HSPB2 heat shock 27kDa protein 2 3.22331
TCF21 transcription factor 21 3.22331
C1ORF87 chromosome 1 open reading frame 87 3.08079
TTPA tocopherol (alpha) transfer protein 3.08079
OVCH2 ovochymase 2 (gene/pseudogene) 3.08079
SLA2 Src-like-adaptor 2 3.08079
PROC protein C (inactivator of coagulation factors Va and VIIIa) 3.08079
ITGA10 integrin, alpha 10 3.08079
F13A1 coagulation factor XIII, A1 polypeptide 3.01115
SPATA13 spermatogenesis associated 13 2.98954
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q 2.96481
S1PR3 sphingosine-1-phosphate receptor 3 2.85995
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal) 2.82282
RAB12 RAB12, member RAS oncogene family 2.70086
SH3RF2 SH3 domain containing ring finger 2 2.69622
PLSCR2 phospholipid scramblase 2 2.69622
PHF8 PHD finger protein 8 2.60778
FNTB farnesyltransferase, CAAX box, beta 2.60659
DPYSL4 dihydropyrimidinase-like 4 2.59871
SGK2 serum/glucocorticoid regulated kinase 2 2.54059
RBM20 RNA binding motif protein 20 2.54059
CDYL chromodomain protein, Y-like 2.51576
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 2.3879
XKRX XK, Kell blood group complex subunit-related, X-linked 2.3727
NUDT10 nudix (nucleoside diphosphate linked moiety X)-type motif 10 2.3727
FNDC8 fibronectin type III domain containing 8 2.3727
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 2.3727
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 2.35933
DRG2 developmentally regulated GTP binding protein 2 2.35321
KRT10 keratin 10, type I 2.33165
ZNF75D zinc finger protein 75D 2.29155
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 2.25133
CDKN2A cyclin-dependent kinase inhibitor 2A 2.25045
LGALS8 lectin, galactoside-binding, soluble, 8 2.24205
PCDH1 protocadherin 1 2.24205
IKZF5 IKAROS family zinc finger 5 (Pegasus) 2.23587
SULT4A1 sulfotransferase family 4A, member 1 2.22794
NUDT8 nudix (nucleoside diphosphate linked moiety X)-type motif 8 2.22529
GYS1 glycogen synthase 1 (muscle) 2.22368
MFAP4 microfibrillar-associated protein 4 2.19381
DNAH11 dynein, axonemal, heavy chain 11 2.19136
NSF N-ethylmaleimide-sensitive factor 2.18638
RPL27 ribosomal protein L27 2.15157
RASL10B RAS-like, family 10, member B 2.1515
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 2.14267
SGPL1 sphingosine-1-phosphate lyase 1 2.09994
ERN1 endoplasmic reticulum to nucleus signaling 1 2.0987
UBAP2 ubiquitin associated protein 2 2.0987
DAPK2 death-associated protein kinase 2 2.08755
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 2.08755
PCDHGB6 protocadherin gamma subfamily B, 6 2.08736
ELL3 elongation factor RNA polymerase II-like 3 2.08736
SP4 Sp4 transcription factor 2.08736
TRHDE thyrotropin-releasing hormone degrading enzyme 2.06374
CDC34 cell division cycle 34 2.04315
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 2.02753
TMEM254 transmembrane protein 254 2.00898

decreased expression

Symbol Name Standardized Value
CFAP52 cilia and flagella associated protein 52 -3.25721
NHLH1 nescient helix loop helix 1 -3.25721
PYY peptide YY -3.25721
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 -3.25721
ZBTB33 zinc finger and BTB domain containing 33 -3.25721
C16ORF89 chromosome 16 open reading frame 89 -3.25721
SFTPD surfactant protein D -3.22331
KRT8 keratin 8, type II -3.22331
FAM86B2 family with sequence similarity 86, member B2 -3.22331
IGFBP3 insulin-like growth factor binding protein 3 -3.22331
VTCN1 V-set domain containing T cell activation inhibitor 1 -3.22331
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 -3.22331
USP50 ubiquitin specific peptidase 50 -3.22331
RNF227 ring finger protein 227 -3.22331
ZNF296 zinc finger protein 296 -3.22331
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -3.22331
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 -3.22331
MMRN2 multimerin 2 -3.22331
RNF112 ring finger protein 112 -3.22331
ADAMTS15 ADAM metallopeptidase with thrombospondin type 1 motif, 15 -3.22331
AQP4 aquaporin 4 -3.22331
TEDC1 tubulin epsilon and delta complex 1 -3.22331
NIBAN3 niban apoptosis regulator 3 -3.22331
PCDHAC1 protocadherin alpha subfamily C, 1 -3.22331
RAG1 recombination activating gene 1 -3.22331
SPRR2F small proline-rich protein 2F -3.22331
PXDC1 PX domain containing 1 -3.22331
ZNF221 zinc finger protein 221 -3.22331
AKR7L aldo-keto reductase family 7-like (gene/pseudogene) -3.22331
LDHAL6A lactate dehydrogenase A-like 6A -3.22331
AKR1D1 aldo-keto reductase family 1, member D1 -3.22331
TLE6 transducin-like enhancer of split 6 -3.22331
CNTNAP1 contactin associated protein 1 -3.22331
SLC22A14 solute carrier family 22, member 14 -3.22331
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -3.22331
H4C6 H4 clustered histone 6 -3.15213
PAQR9 progestin and adipoQ receptor family member IX -3.03131
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 -2.84342
BICDL2 BICD family like cargo adaptor 2 -2.81111
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -2.70086
RAD9A RAD9 homolog A (S. pombe) -2.69371
MVD mevalonate (diphospho) decarboxylase -2.54729
STYX serine/threonine/tyrosine interacting protein -2.51576
NCF2 neutrophil cytosolic factor 2 -2.5076
CALB1 calbindin 1, 28kDa -2.50556
PDGFC platelet derived growth factor C -2.42635
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -2.42253
KRT19 keratin 19, type I -2.3879
WDR7 WD repeat domain 7 -2.3879
ZNF774 zinc finger protein 774 -2.38373
TAFA4 TAFA chemokine like family member 4 -2.35538
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) -2.35044
PINLYP phospholipase A2 inhibitor and LY6/PLAUR domain containing -2.34192
OTOGL otogelin-like -2.34037
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) -2.31811
CLIP2 CAP-GLY domain containing linker protein 2 -2.24698
TMEM127 transmembrane protein 127 -2.24205
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1 -2.24205
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 -2.24128
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 -2.2129
ZNF671 zinc finger protein 671 -2.2129
SYT3 synaptotagmin III -2.2129
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) -2.20928
SUSD2 sushi domain containing 2 -2.20494
LEAP2 liver expressed antimicrobial peptide 2 -2.20494
MRPS12 mitochondrial ribosomal protein S12 -2.19757
TRMO tRNA methyltransferase O -2.19706
ASIC1 acid sensing (proton gated) ion channel 1 -2.19706
TSLP thymic stromal lymphopoietin -2.19706
IL11RA interleukin 11 receptor, alpha -2.19706
MBLAC1 metallo-beta-lactamase domain containing 1 -2.19706
LMNB2 lamin B2 -2.19217
RAP2C RAP2C, member of RAS oncogene family -2.18638
SET SET nuclear proto-oncogene -2.178
CDYL2 chromodomain protein, Y-like 2 -2.178
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7 -2.1777
ATF1 activating transcription factor 1 -2.16553
CEPT1 choline/ethanolamine phosphotransferase 1 -2.1515
ZNF114 zinc finger protein 114 -2.1311
RINT1 RAD50 interactor 1 -2.13003
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle -2.12066
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 -2.11443
BIRC5 baculoviral IAP repeat containing 5 -2.10759
ZC3H10 zinc finger CCCH-type containing 10 -2.07996
WDR6 WD repeat domain 6 -2.079
MRFAP1L1 Morf4 family associated protein 1-like 1 -2.06657
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I -2.06374
MTMR1 myotubularin related protein 1 -2.06284
BPNT2 3'(2'), 5'-bisphosphate nucleotidase 2 -2.05012
NONO non-POU domain containing, octamer-binding -2.04909
RAB5C RAB5C, member RAS oncogene family -2.04909
EXOSC10 exosome component 10 -2.04821
SFMBT2 Scm-like with four mbt domains 2 -2.04096
JPT2 Jupiter microtubule associated homolog 2 -2.04096
NADK2 NAD kinase 2, mitochondrial -2.03516
ARHGAP26 Rho GTPase activating protein 26 -2.03242
TEX2 testis expressed 2 -2.03242
KIF24 kinesin family member 24 -2.03227