| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/GCNP_SHH_UP_LATE.V1_UP |
| Similar Terms | |
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362 genes differentially expressed following the GCNP_SHH_UP_LATE.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| AARD | alanine and arginine rich domain containing protein |
| ABCE1 | ATP-binding cassette, sub-family E (OABP), member 1 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 |
| ARL5A | ADP-ribosylation factor-like 5A |
| ASB3 | ankyrin repeat and SOCS box containing 3 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| AURKA | aurora kinase A |
| AURKB | aurora kinase B |
| BOK | BCL2-related ovarian killer |
| C1ORF174 | chromosome 1 open reading frame 174 |
| CASD1 | CAS1 domain containing 1 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCND2 | cyclin D2 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CD5 | CD5 molecule |
| CD6 | CD6 molecule |
| CD80 | CD80 molecule |
| CDC25A | cell division cycle 25A |
| CDC25C | cell division cycle 25C |
| CDCA7 | cell division cycle associated 7 |
| CDK1 | cyclin-dependent kinase 1 |
| CFDP1 | craniofacial development protein 1 |
| CHEK1 | checkpoint kinase 1 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLIC4 | chloride intracellular channel 4 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| COIL | coilin |
| COPB1 | coatomer protein complex, subunit beta 1 |
| COX7B | cytochrome c oxidase subunit VIIb |
| CREM | cAMP responsive element modulator |
| CUL4A | cullin 4A |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DDX39A | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DES | desmin |
| DIDO1 | death inducer-obliterator 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNM1L | dynamin 1-like |
| E2F8 | E2F transcription factor 8 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa |
| EIF3A | eukaryotic translation initiation factor 3, subunit A |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ELOVL2 | ELOVL fatty acid elongase 2 |
| FAM60A | family with sequence similarity 60, member A |
| FANCC | Fanconi anemia, complementation group C |
| FANCM | Fanconi anemia, complementation group M |
| FBXO11 | F-box protein 11 |
| FMR1NB | fragile X mental retardation 1 neighbor |
| FOXA1 | forkhead box A1 |
| FRMD6 | FERM domain containing 6 |
| FTSJ3 | FtsJ homolog 3 (E. coli) |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GFM2 | G elongation factor, mitochondrial 2 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| HIGD1A | HIG1 hypoxia inducible domain family, member 1A |
| HNF1A | HNF1 homeobox A |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 |
| HNRNPU-AS1 | HNRNPU antisense RNA 1 |
| HSPB2 | heat shock 27kDa protein 2 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IGF2 | insulin-like growth factor 2 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IVNS1ABP | influenza virus NS1A binding protein |
| KIF2C | kinesin family member 2C |
| KIFC1 | kinesin family member C1 |
| KRTAP6-3 | keratin associated protein 6-3 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LBR | lamin B receptor |
| LEFTY1 | left-right determination factor 1 |
| LIG1 | ligase I, DNA, ATP-dependent |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) |
| LOXL2 | lysyl oxidase-like 2 |
| LRRC23 | leucine rich repeat containing 23 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) |
| MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) |
| MAP3K7 | mitogen-activated protein kinase kinase kinase 7 |
| MATR3 | matrin 3 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MCM6 | minichromosome maintenance complex component 6 |
| MDN1 | MDN1, midasin homolog (yeast) |
| METAP1 | methionyl aminopeptidase 1 |
| MIOS | missing oocyte, meiosis regulator, homolog (Drosophila) |
| MIS18BP1 | MIS18 binding protein 1 |
| MOB1A | MOB kinase activator 1A |
| MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) |
| MRPL18 | mitochondrial ribosomal protein L18 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MUC1 | mucin 1, cell surface associated |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit |
| NAA30 | N(alpha)-acetyltransferase 30, NatC catalytic subunit |
| NKX2-2 | NK2 homeobox 2 |
| NOP56 | NOP56 ribonucleoprotein |
| NPAS1 | neuronal PAS domain protein 1 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) |
| NPTX1 | neuronal pentraxin I |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 |
| NTMT1 | N-terminal Xaa-Pro-Lys N-methyltransferase 1 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| NXF1 | nuclear RNA export factor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PBDC1 | polysaccharide biosynthesis domain containing 1 |
| PCNT | pericentrin |
| PCSK2 | proprotein convertase subtilisin/kexin type 2 |
| PFDN6 | prefoldin subunit 6 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PLEKHA7 | pleckstrin homology domain containing, family A member 7 |
| PLK2 | polo-like kinase 2 |
| POLA2 | polymerase (DNA directed), alpha 2, accessory subunit |
| POLRMT | polymerase (RNA) mitochondrial (DNA directed) |
| PRC1 | protein regulator of cytokinesis 1 |
| PSMC3IP | PSMC3 interacting protein |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 |
| PTCD3 | pentatricopeptide repeat domain 3 |
| PTPRC | protein tyrosine phosphatase, receptor type, C |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAG2 | recombination activating gene 2 |
| RLIM | ring finger protein, LIM domain interacting |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| RYK | receptor-like tyrosine kinase |
| SACM1L | SAC1 suppressor of actin mutations 1-like (yeast) |
| SARDH | sarcosine dehydrogenase |
| SDC2 | syndecan 2 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SFRP1 | secreted frizzled-related protein 1 |
| SGOL1 | shugoshin-like 1 (S. pombe) |
| SIX4 | SIX homeobox 4 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC7A6 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| SLTM | SAFB-like, transcription modulator |
| SMC2 | structural maintenance of chromosomes 2 |
| SMC4 | structural maintenance of chromosomes 4 |
| SMIM11 | small integral membrane protein 11 |
| SMIM20 | small integral membrane protein 20 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SPATA5 | spermatogenesis associated 5 |
| SPOP | speckle-type POZ protein |
| SQRDL | sulfide quinone reductase-like (yeast) |
| SRSF1 | serine/arginine-rich splicing factor 1 |
| SRSF10 | serine/arginine-rich splicing factor 10 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STRN3 | striatin, calmodulin binding protein 3 |
| SYT4 | synaptotagmin IV |
| TARDBP | TAR DNA binding protein |
| TEAD3 | TEA domain family member 3 |
| THOP1 | thimet oligopeptidase 1 |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TK1 | thymidine kinase 1, soluble |
| TM9SF3 | transmembrane 9 superfamily member 3 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TOP2B | topoisomerase (DNA) II beta 180kDa |
| TRIP13 | thyroid hormone receptor interactor 13 |
| UFD1L | ubiquitin fusion degradation 1 like (yeast) |
| UNG | uracil-DNA glycosylase |
| USP39 | ubiquitin specific peptidase 39 |
| VCAN | versican |
| VPRBP | Vpr (HIV-1) binding protein |
| VPS4B | vacuolar protein sorting 4 homolog B (S. cerevisiae) |
| XPO1 | exportin 1 |
| YTHDF3 | YTH N(6)-methyladenosine RNA binding protein 3 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZFX | zinc finger protein, X-linked |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZMYM6 | zinc finger, MYM-type 6 |
| ZNF281 | zinc finger protein 281 |
| ZNF638 | zinc finger protein 638 |
| ZNF644 | zinc finger protein 644 |
| Symbol | Name |
|---|---|
| ACOT1 | acyl-CoA thioesterase 1 |
| ACTN4 | actinin, alpha 4 |
| ACVR1 | activin A receptor, type I |
| ADAM7 | ADAM metallopeptidase domain 7 |
| ADCY9 | adenylate cyclase 9 |
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide |
| ADRB2 | adrenoceptor beta 2, surface |
| AGER | advanced glycosylation end product-specific receptor |
| AGTRAP | angiotensin II receptor-associated protein |
| AMOTL2 | angiomotin like 2 |
| ANKRD33B | ankyrin repeat domain 33B |
| ANXA7 | annexin A7 |
| ARAF | A-Raf proto-oncogene, serine/threonine kinase |
| ARG1 | arginase 1 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ART5 | ADP-ribosyltransferase 5 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| AXIN1 | axin 1 |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| BCL2L2 | BCL2-like 2 |
| C19ORF60 | chromosome 19 open reading frame 60 |
| CCDC71L | coiled-coil domain containing 71-like |
| CD276 | CD276 molecule |
| CD52 | CD52 molecule |
| CDCP1 | CUB domain containing protein 1 |
| CDHR5 | cadherin-related family member 5 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLRN3 | clarin 3 |
| CNGA2 | cyclic nucleotide gated channel alpha 2 |
| CNN1 | calponin 1, basic, smooth muscle |
| CNN2 | calponin 2 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CSF2RBP1 | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) pseudogene 1 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked |
| DLG4 | discs, large homolog 4 (Drosophila) |
| DLX5 | distal-less homeobox 5 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DPPA5 | developmental pluripotency associated 5 |
| DSCR8 | Down syndrome critical region 8 |
| EBI3 | Epstein-Barr virus induced 3 |
| EDN1 | endothelin 1 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 |
| EIF4ENIF1 | eukaryotic translation initiation factor 4E nuclear import factor 1 |
| EIF6 | eukaryotic translation initiation factor 6 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| EPHA3 | EPH receptor A3 |
| EPHB6 | EPH receptor B6 |
| ESRP1 | epithelial splicing regulatory protein 1 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 |
| F8A1 | coagulation factor VIII-associated 1 |
| FAHD1 | fumarylacetoacetate hydrolase domain containing 1 |
| FAM111A | family with sequence similarity 111, member A |
| FCGRT | Fc fragment of IgG, receptor, transporter, alpha |
| FMO1 | flavin containing monooxygenase 1 |
| FOXD3 | forkhead box D3 |
| FRRS1 | ferric-chelate reductase 1 |
| FZD9 | frizzled class receptor 9 |
| GCM2 | glial cells missing homolog 2 (Drosophila) |
| GJB6 | gap junction protein, beta 6, 30kDa |
| GLA | galactosidase, alpha |
| GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPR3 | G protein-coupled receptor 3 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| H2AFJ | H2A histone family, member J |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| HYOU1 | hypoxia up-regulated 1 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL4R | interleukin 4 receptor |
| IRF9 | interferon regulatory factor 9 |
| ITGA7 | integrin, alpha 7 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) |
| KANK3 | KN motif and ankyrin repeat domains 3 |
| KIAA1161 | KIAA1161 |
| KLK6 | kallikrein-related peptidase 6 |
| KLK8 | kallikrein-related peptidase 8 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) |
| LAMC2 | laminin, gamma 2 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LOR | loricrin |
| LSR | lipolysis stimulated lipoprotein receptor |
| LTA | lymphotoxin alpha |
| LTC4S | leukotriene C4 synthase |
| LYSMD1 | LysM, putative peptidoglycan-binding, domain containing 1 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MDFI | MyoD family inhibitor |
| MED12 | mediator complex subunit 12 |
| MEF2A | myocyte enhancer factor 2A |
| MIIP | migration and invasion inhibitory protein |
| MLLT1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| MRPL3 | mitochondrial ribosomal protein L3 |
| MUC3A | mucin 3A, cell surface associated |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NBEAL2 | neurobeachin-like 2 |
| NCOA6 | nuclear receptor coactivator 6 |
| NCOA7 | nuclear receptor coactivator 7 |
| NDUFA10 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa |
| NECAP2 | NECAP endocytosis associated 2 |
| NMI | N-myc (and STAT) interactor |
| NPTN | neuroplastin |
| NRP2 | neuropilin 2 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| OGG1 | 8-oxoguanine DNA glycosylase |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PDCD7 | programmed cell death 7 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEMT | phosphatidylethanolamine N-methyltransferase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PITX3 | paired-like homeodomain 3 |
| PLD2 | phospholipase D2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPM1M | protein phosphatase, Mg2+/Mn2+ dependent, 1M |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTH1R | parathyroid hormone 1 receptor |
| PTPN18 | protein tyrosine phosphatase, non-receptor type 18 (brain-derived) |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| PUS1 | pseudouridylate synthase 1 |
| RAB34 | RAB34, member RAS oncogene family |
| RBBP6 | retinoblastoma binding protein 6 |
| RBKS | ribokinase |
| RHD | Rh blood group, D antigen |
| RMDN3 | regulator of microtubule dynamics 3 |
| RP9 | retinitis pigmentosa 9 (autosomal dominant) |
| S100A11 | S100 calcium binding protein A11 |
| S100A13 | S100 calcium binding protein A13 |
| S1PR1 | sphingosine-1-phosphate receptor 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SELL | selectin L |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3BGRL2 | SH3 domain binding glutamate-rich protein like 2 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC25A45 | solute carrier family 25, member 45 |
| SLC25A47 | solute carrier family 25, member 47 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SNX21 | sorting nexin family member 21 |
| SOX18 | SRY (sex determining region Y)-box 18 |
| SSBP4 | single stranded DNA binding protein 4 |
| STX1A | syntaxin 1A (brain) |
| STX2 | syntaxin 2 |
| STX3 | syntaxin 3 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TGFB3 | transforming growth factor, beta 3 |
| TMEM214 | transmembrane protein 214 |
| TNNC1 | troponin C type 1 (slow) |
| TNNC2 | troponin C type 2 (fast) |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA4B | tubulin, alpha 4b |
| UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 |
| UBE3C | ubiquitin protein ligase E3C |
| VEGFC | vascular endothelial growth factor C |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VNN1 | vanin 1 |
| VSNL1 | visinin-like 1 |
| WIPI2 | WD repeat domain, phosphoinositide interacting 2 |
| WLS | wntless Wnt ligand secretion mediator |
| WNK2 | WNK lysine deficient protein kinase 2 |
| WWC1 | WW and C2 domain containing 1 |
| ZC3H12C | zinc finger CCCH-type containing 12C |
| ZDHHC5 | zinc finger, DHHC-type containing 5 |
| ZFYVE19 | zinc finger, FYVE domain containing 19 |
| ZIK1 | zinc finger protein interacting with K protein 1 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
