GEM Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description GTP binding protein overexpressed in skeletal muscle|The protein encoded by this gene belongs to the RAD/GEM family of GTP-binding proteins. It is associated with the inner face of the plasma membrane and could play a role as a regulatory protein in receptor-mediated signal transduction. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2669)
External Link https://ncbi.nlm.nih.gov/gene/2669
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Genes

499 genes differentially expressed following the GEM gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
LTF lactotransferrin 0.02414
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0223636
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.016836
JCHAIN joining chain of multimeric IgA and IgM 0.0158813
RAI14 retinoic acid induced 14 0.015128
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.014515
KDM5D lysine (K)-specific demethylase 5D 0.0139926
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0135738
VCAM1 vascular cell adhesion molecule 1 0.0130333
MLF1 myeloid leukemia factor 1 0.0126631
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0126442
MLPH melanophilin 0.0123606
CXCL9 chemokine (C-X-C motif) ligand 9 0.0122328
TUBB2A tubulin, beta 2A class IIa 0.0122149
PLAAT3 phospholipase A and acyltransferase 3 0.0119975
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.0112097
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0107616
IDO1 indoleamine 2,3-dioxygenase 1 0.0107565
GREM1 gremlin 1, DAN family BMP antagonist 0.010615
SCGB2A2 secretoglobin, family 2A, member 2 0.0102527
ACP5 acid phosphatase 5, tartrate resistant 0.0100591
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0100473
IVNS1ABP influenza virus NS1A binding protein 0.0099948
TSPAN13 tetraspanin 13 0.00992671
DIPK1A divergent protein kinase domain 1A 0.00989244
PLIN2 perilipin 2 0.00967495
CD58 CD58 molecule 0.00958
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0095761
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00956268
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.0094644
PLXNC1 plexin C1 0.00928696
MME membrane metallo-endopeptidase 0.00921535
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.00893572
C10ORF10 chromosome 10 open reading frame 10 0.00882064
CYTIP cytohesin 1 interacting protein 0.00881529
ISG15 ISG15 ubiquitin-like modifier 0.00880042
STAT1 signal transducer and activator of transcription 1, 91kDa 0.00879927
SCGB1D2 secretoglobin, family 1D, member 2 0.00872366
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.00870819
CTSK cathepsin K 0.00867763
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00865653
OXA1L oxidase (cytochrome c) assembly 1-like 0.00860995
CD59 CD59 molecule, complement regulatory protein 0.00856158
COG2 component of oligomeric golgi complex 2 0.00854271
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00845588
CXCL14 chemokine (C-X-C motif) ligand 14 0.00830124
STK10 serine/threonine kinase 10 0.00829779
NPY1R neuropeptide Y receptor Y1 0.00828308
QDPR quinoid dihydropteridine reductase 0.00825045
POU2AF1 POU class 2 associating factor 1 0.00821995
BIRC2 baculoviral IAP repeat containing 2 0.00814917
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 0.00807706
SELL selectin L 0.00799434
SDC1 syndecan 1 0.00795765
RSAD2 radical S-adenosyl methionine domain containing 2 0.00793175
DEPTOR DEP domain containing MTOR-interacting protein 0.00793169
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.00787034
TFR2 transferrin receptor 2 0.00784044
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00783125
RCAN1 regulator of calcineurin 1 0.00781347
ARG1 arginase 1 0.00780429
VNN1 vanin 1 0.00779992
PLBD1 phospholipase B domain containing 1 0.00779284
PROM1 prominin 1 0.00778738
SLAMF7 SLAM family member 7 0.00775891
GAL galanin/GMAP prepropeptide 0.00773731
IFI27 interferon, alpha-inducible protein 27 0.00769432
GPM6B glycoprotein M6B 0.00768175
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00757627
RGS1 regulator of G-protein signaling 1 0.00752617
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 0.00752515
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog 0.00750631
MFAP3L microfibrillar-associated protein 3-like 0.00748612
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.0074404
NDN necdin, melanoma antigen (MAGE) family member 0.00740173
ASRGL1 asparaginase like 1 0.00733433
GALC galactosylceramidase 0.00732672
SORBS2 sorbin and SH3 domain containing 2 0.00730722
BIRC3 baculoviral IAP repeat containing 3 0.0072663
CD36 CD36 molecule (thrombospondin receptor) 0.00726473
PWP1 PWP1 homolog (S. cerevisiae) 0.0072193
MSMB microseminoprotein, beta- 0.00715639
IL7R interleukin 7 receptor 0.00714458
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00713801
CRISP3 cysteine-rich secretory protein 3 0.00713793
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00708838
PLS1 plastin 1 0.00708128
TUBA1A tubulin, alpha 1a 0.00703983
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.00699628
NNMT nicotinamide N-methyltransferase 0.00699398
EAF2 ELL associated factor 2 0.00699313
TADA2A transcriptional adaptor 2A 0.00698715
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 0.0069642
GPNMB glycoprotein (transmembrane) nmb 0.00693359
PBLD phenazine biosynthesis-like protein domain containing 0.00693227
GPC4 glypican 4 0.0069039
IGLL1 immunoglobulin lambda-like polypeptide 1 0.00687446
INSM1 insulinoma-associated 1 0.00686375
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00686292
F5 coagulation factor V (proaccelerin, labile factor) 0.00684184
RUNX3 runt-related transcription factor 3 0.00683695
ALDOB aldolase B, fructose-bisphosphate 0.00681656
ATF3 activating transcription factor 3 0.0068103
UROD uroporphyrinogen decarboxylase 0.00680547
FKBP11 FK506 binding protein 11, 19 kDa 0.00679777
DCXR dicarbonyl/L-xylulose reductase 0.00679674
ZMIZ2 zinc finger, MIZ-type containing 2 0.00679564
PCNA proliferating cell nuclear antigen 0.00677664
OLFM4 olfactomedin 4 0.00677432
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 0.00675671
CD52 CD52 molecule 0.00673865
MRPS2 mitochondrial ribosomal protein S2 0.00673289
CD40 CD40 molecule, TNF receptor superfamily member 5 0.00671873
DERA deoxyribose-phosphate aldolase (putative) 0.00670198
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.00670151
TBC1D4 TBC1 domain family, member 4 0.00670113
CXCL13 chemokine (C-X-C motif) ligand 13 0.00668683
PUF60 poly-U binding splicing factor 60KDa 0.00665255
STOM stomatin 0.00660011
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.00656953
AGTR1 angiotensin II receptor, type 1 0.00655707
KLF10 Kruppel-like factor 10 0.00652641
ICAM2 intercellular adhesion molecule 2 0.00651743
TMSB15A thymosin beta 15a 0.00651211
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00650513
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.00650231
GPR137B G protein-coupled receptor 137B 0.00649378
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00643797
GPX4 glutathione peroxidase 4 0.00641941
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.00641303
CD48 CD48 molecule 0.00636872
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00634099
G6PC glucose-6-phosphatase, catalytic subunit 0.0063316
FTH1 ferritin, heavy polypeptide 1 0.0063268
IFI44L interferon-induced protein 44-like 0.0063065
RNASE6 ribonuclease, RNase A family, k6 0.00629857
ELF5 E74-like factor 5 (ets domain transcription factor) 0.00628815
CCL19 chemokine (C-C motif) ligand 19 0.00628113
CPM carboxypeptidase M 0.00626767
C9ORF116 chromosome 9 open reading frame 116 0.00625003
TMC5 transmembrane channel-like 5 0.00624593
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.00624421
GAS1 growth arrest-specific 1 0.00623456
SCGB2A1 secretoglobin, family 2A, member 1 0.00623231
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 0.00622299
TOX3 TOX high mobility group box family member 3 0.00620433
CCR7 chemokine (C-C motif) receptor 7 0.0061754
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase 0.00617382
QPCT glutaminyl-peptide cyclotransferase 0.00617221
ZSCAN18 zinc finger and SCAN domain containing 18 0.00613423
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 0.00613143
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.0061279
EFHD1 EF-hand domain family, member D1 0.00612452
ANXA10 annexin A10 0.00611691
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.00611066
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00610256
MIA melanoma inhibitory activity 0.0060999
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00608627
CUTA cutA divalent cation tolerance homolog (E. coli) 0.00605941
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.00602541
CXCL10 chemokine (C-X-C motif) ligand 10 0.00599899
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.00599807
SIK1 salt-inducible kinase 1 0.00599568
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 0.00599247
FAR2 fatty acyl CoA reductase 2 0.00599131
NVL nuclear VCP-like 0.00597398
C8ORF4 chromosome 8 open reading frame 4 0.00597385
TNFRSF17 tumor necrosis factor receptor superfamily, member 17 0.0059684
MYH10 myosin, heavy chain 10, non-muscle 0.00594937
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0059401
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00593903
GEM GTP binding protein overexpressed in skeletal muscle 0.0059341
DHDDS dehydrodolichyl diphosphate synthase 0.00593222
SCO2 SCO2 cytochrome c oxidase assembly protein 0.00592884
FAM46C family with sequence similarity 46, member C 0.00592497
CD300A CD300a molecule 0.00592449
DNASE1L3 deoxyribonuclease I-like 3 0.00591995
PECR peroxisomal trans-2-enoyl-CoA reductase 0.00591235
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 0.00590523
NEBL nebulette 0.005905
OSBPL8 oxysterol binding protein-like 8 0.00590429
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00589891
MCAM melanoma cell adhesion molecule 0.00589455
COL10A1 collagen, type X, alpha 1 0.00588257
LCK LCK proto-oncogene, Src family tyrosine kinase 0.00586745
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.00586187
S100A7 S100 calcium binding protein A7 0.00585887
NARF nuclear prelamin A recognition factor 0.00585402
SIDT1 SID1 transmembrane family, member 1 0.00584833
PLA1A phospholipase A1 member A 0.00583425
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5 0.0058227
ACTN1 actinin, alpha 1 0.00580472
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding) 0.00578411
AQP9 aquaporin 9 0.00577359
NRIP3 nuclear receptor interacting protein 3 0.00577272
PLK2 polo-like kinase 2 0.00576974
TMEM131L transmembrane 131 like 0.00576363
APOD apolipoprotein D 0.0057611
ARL4A ADP-ribosylation factor-like 4A 0.00575467
CTSZ cathepsin Z 0.00571329
ARFIP1 ADP-ribosylation factor interacting protein 1 0.00570552
CRELD2 cysteine-rich with EGF-like domains 2 0.00569974
MZB1 marginal zone B and B1 cell-specific protein 0.00567309
UBAC1 UBA domain containing 1 0.00566832
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1 0.00566774
GSTZ1 glutathione S-transferase zeta 1 0.00566634
PIP prolactin-induced protein 0.00566605
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.00566437
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa 0.00566404
DCT dopachrome tautomerase 0.0056614
MAN1C1 mannosidase, alpha, class 1C, member 1 0.00565761
MAGEA12 melanoma antigen family A12 0.00565539
RAB38 RAB38, member RAS oncogene family 0.00564508
ORC1 origin recognition complex, subunit 1 0.00564177
SDC3 syndecan 3 0.00563716
GNG7 guanine nucleotide binding protein (G protein), gamma 7 0.00561986
CDC20 cell division cycle 20 0.00561362
MMP8 matrix metallopeptidase 8 0.00560737
SLC44A4 solute carrier family 44, member 4 0.00559474
ROPN1B rhophilin associated tail protein 1B 0.00558183
CLC Charcot-Leyden crystal galectin 0.00554727
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00554687
ELOVL5 ELOVL fatty acid elongase 5 0.00553032
EGOT eosinophil granule ontogeny transcript (non-protein coding) 0.0055286
EFNB2 ephrin-B2 0.00552742
EPCAM epithelial cell adhesion molecule 0.00551108
RPA2 replication protein A2, 32kDa 0.00551006
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.00550873
PMEL premelanosome protein 0.00550314
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2 0.00549617
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) 0.0054904
ACOT13 acyl-CoA thioesterase 13 0.00547995
CFAP45 cilia and flagella associated protein 45 0.00547415
CREBL2 cAMP responsive element binding protein-like 2 0.00546267
GCH1 GTP cyclohydrolase 1 0.00545728
IRF7 interferon regulatory factor 7 0.00544755
ACP3 acid phosphatase 3 0.00544387
CXCL11 chemokine (C-X-C motif) ligand 11 0.00542999
GFI1B growth factor independent 1B transcription repressor 0.00539722
OGFRL1 opioid growth factor receptor-like 1 0.00539545
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00538881
MAGEA3 melanoma antigen family A3 0.00538444
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00538026
NID2 nidogen 2 (osteonidogen) 0.00537944
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00536681
RPA3 replication protein A3, 14kDa 0.00536596
NID1 nidogen 1 0.00534922
CD69 CD69 molecule 0.00534355
ADD2 adducin 2 (beta) 0.00533626

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0177015
SLC38A1 solute carrier family 38, member 1 -0.0162974
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.0140729
SEPP1 selenoprotein P, plasma, 1 -0.0138466
F13A1 coagulation factor XIII, A1 polypeptide -0.0134822
SNAP25 synaptosomal-associated protein, 25kDa -0.0114338
AHNAK AHNAK nucleoprotein -0.01093
MEG3 maternally expressed 3 (non-protein coding) -0.0105596
NDRG1 N-myc downstream regulated 1 -0.010373
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon -0.0101628
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0101506
CPE carboxypeptidase E -0.0101445
GOLGA8A golgin A8 family, member A -0.00994544
GPC3 glypican 3 -0.00975337
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.00971558
WT1 Wilms tumor 1 -0.00948402
CST3 cystatin C -0.00945351
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00944507
CADM1 cell adhesion molecule 1 -0.0094325
TM4SF1 transmembrane 4 L six family member 1 -0.00940683
VSNL1 visinin-like 1 -0.00936397
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00916653
FGFBP1 fibroblast growth factor binding protein 1 -0.009101
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00903536
SMC1A structural maintenance of chromosomes 1A -0.00902723
P3H2 prolyl 3-hydroxylase 2 -0.0089205
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) -0.00886568
PCP4 Purkinje cell protein 4 -0.00885949
PPL periplakin -0.00883079
ZFPM2 zinc finger protein, FOG family member 2 -0.00879743
NDFIP1 Nedd4 family interacting protein 1 -0.00879533
MECOM MDS1 and EVI1 complex locus -0.00870114
NOTCH2NL notch 2 N-terminal like -0.00868928
NRCAM neuronal cell adhesion molecule -0.00852172
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.00851845
NPIPB3 nuclear pore complex interacting protein family, member B3 -0.00847887
NIBAN1 niban apoptosis regulator 1 -0.00839406
ZNF185 zinc finger protein 185 (LIM domain) -0.00834471
RHOBTB3 Rho-related BTB domain containing 3 -0.00819288
TMEM100 transmembrane protein 100 -0.00815616
AZU1 azurocidin 1 -0.0081514
ABLIM1 actin binding LIM protein 1 -0.00805253
SPRR2B small proline-rich protein 2B -0.00804484
PRKCA protein kinase C, alpha -0.00799224
FLNA filamin A, alpha -0.00795995
PDGFC platelet derived growth factor C -0.00789052
GUCY2C guanylate cyclase 2C -0.00787225
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00786172
ZNF160 zinc finger protein 160 -0.00781125
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00779892
AKR1C3 aldo-keto reductase family 1, member C3 -0.00777779
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon -0.00773968
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor -0.00773446
THBS4 thrombospondin 4 -0.00769539
CREB3L2 cAMP responsive element binding protein 3-like 2 -0.00768978
SETD5 SET domain containing 5 -0.00768248
EMP1 epithelial membrane protein 1 -0.00763045
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00758638
SYT1 synaptotagmin I -0.00758637
DSG3 desmoglein 3 -0.00752699
HOPX HOP homeobox -0.0074958
SOBP sine oculis binding protein homolog (Drosophila) -0.00749221
TRIB3 tribbles pseudokinase 3 -0.00748963
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.00747675
CUX1 cut-like homeobox 1 -0.00746709
GAB2 GRB2-associated binding protein 2 -0.00744825
TMEM43 transmembrane protein 43 -0.00740334
DMD dystrophin -0.00732936
NCAM1 neural cell adhesion molecule 1 -0.00725697
NEFM neurofilament, medium polypeptide -0.00723712
AUTS2 autism susceptibility candidate 2 -0.00721459
TPD52L1 tumor protein D52-like 1 -0.00720656
LAMB3 laminin, beta 3 -0.00719741
CAPN2 calpain 2, (m/II) large subunit -0.00719224
TRIO trio Rho guanine nucleotide exchange factor -0.0071914
ADIRF adipogenesis regulatory factor -0.00718694
C7 complement component 7 -0.00715412
MKNK1 MAP kinase interacting serine/threonine kinase 1 -0.00713624
NPTX1 neuronal pentraxin I -0.00712446
MSLN mesothelin -0.00711543
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00706361
MSANTD2 Myb/SANT-like DNA-binding domain containing 2 -0.00705576
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00704937
DLK1 delta-like 1 homolog (Drosophila) -0.00700393
ZNF721 zinc finger protein 721 -0.00698005
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.00697946
MMP2 matrix metallopeptidase 2 -0.00693111
LTBP2 latent transforming growth factor beta binding protein 2 -0.00687376
AHCYL1 adenosylhomocysteinase-like 1 -0.00685824
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.00684485
KIAA0100 KIAA0100 -0.00683564
RBMS1 RNA binding motif, single stranded interacting protein 1 -0.00683037
CD9 CD9 molecule -0.00681486
CFD complement factor D (adipsin) -0.00679005
FRY furry homolog (Drosophila) -0.0067845
TSPAN7 tetraspanin 7 -0.00676886
GBP2 guanylate binding protein 2, interferon-inducible -0.00676291
PEG3 paternally expressed 3 -0.00675572
PRR11 proline rich 11 -0.00674407
TNNT1 troponin T type 1 (skeletal, slow) -0.00671368
FOSL2 FOS-like antigen 2 -0.00669155
AKR1C2 aldo-keto reductase family 1, member C2 -0.00666563
BCL3 B-cell CLL/lymphoma 3 -0.00666446
TMBIM1 transmembrane BAX inhibitor motif containing 1 -0.00663938
SPRR3 small proline-rich protein 3 -0.00663406
PRSS3 protease, serine, 3 -0.00662812
LYPD1 LY6/PLAUR domain containing 1 -0.00662698
MSL1 male-specific lethal 1 homolog (Drosophila) -0.00662102
HSPA1A heat shock 70kDa protein 1A -0.00657423
TPBG trophoblast glycoprotein -0.00656779
ASS1 argininosuccinate synthase 1 -0.00654117
LMO3 LIM domain only 3 (rhombotin-like 2) -0.00653427
IGHMBP2 immunoglobulin mu binding protein 2 -0.00651928
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.00651879
TGM1 transglutaminase 1 -0.00651445
GAP43 growth associated protein 43 -0.0065048
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00650142
FGB fibrinogen beta chain -0.00649077
CA11 carbonic anhydrase XI -0.00648396
AKR1C1 aldo-keto reductase family 1, member C1 -0.00645855
OGN osteoglycin -0.00642675
S100A10 S100 calcium binding protein A10 -0.00642306
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -0.00641526
CSF1R colony stimulating factor 1 receptor -0.00639281
ZNF611 zinc finger protein 611 -0.00638469
CRYAB crystallin, alpha B -0.00637357
GYS1 glycogen synthase 1 (muscle) -0.0063718
PDE4D phosphodiesterase 4D, cAMP-specific -0.00635315
TGFBR3 transforming growth factor, beta receptor III -0.00634972
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 -0.00632681
MTUS1 microtubule associated tumor suppressor 1 -0.00631059
HAUS2 HAUS augmin-like complex, subunit 2 -0.0063072
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 -0.00630077
RGS13 regulator of G-protein signaling 13 -0.00629365
MN1 meningioma (disrupted in balanced translocation) 1 -0.00627914
FBN2 fibrillin 2 -0.00626913
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00625957
ELP1 elongator acetyltransferase complex subunit 1 -0.00625056
STAB1 stabilin 1 -0.00621269
ATAD2 ATPase family, AAA domain containing 2 -0.00620421
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.00620077
PHACTR2 phosphatase and actin regulator 2 -0.00618693
CLU clusterin -0.00615964
KDM6A lysine (K)-specific demethylase 6A -0.00615434
ANKRD10 ankyrin repeat domain 10 -0.00615333
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.00612213
RASA4 RAS p21 protein activator 4 -0.00606757
VEGFA vascular endothelial growth factor A -0.00604529
PXDN peroxidasin -0.00601574
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00600827
CHGB chromogranin B -0.00600224
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00599419
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) -0.00599013
PITX1 paired-like homeodomain 1 -0.00598664
PKP1 plakophilin 1 -0.00598267
IL1RAP interleukin 1 receptor accessory protein -0.00597507
WWC3 WWC family member 3 -0.00595053
ELANE elastase, neutrophil expressed -0.0059491
RNPS1 RNA binding protein S1, serine-rich domain -0.00593221
HACD2 3-hydroxyacyl-CoA dehydratase 2 -0.00593219
BCAT2 branched chain amino-acid transaminase 2, mitochondrial -0.00590876
PRMT1 protein arginine methyltransferase 1 -0.00590586
TMCC1 transmembrane and coiled-coil domain family 1 -0.00589408
MEIS1 Meis homeobox 1 -0.00589318
TTN titin -0.00588721
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric) -0.00588287
IL6 interleukin 6 -0.00587687
NPIPA1 nuclear pore complex interacting protein family, member A1 -0.00586478
PDE10A phosphodiesterase 10A -0.00586221
PMM2 phosphomannomutase 2 -0.0058618
PRSS21 protease, serine, 21 (testisin) -0.00583066
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) -0.00583
SLC35G2 solute carrier family 35, member G2 -0.00582636
TCAF1 TRPM8 channel-associated factor 1 -0.00582309
CTSG cathepsin G -0.00581706
SPRR1A small proline-rich protein 1A -0.00581586
BCL6 B-cell CLL/lymphoma 6 -0.00580875
LOX lysyl oxidase -0.00580591
SLN sarcolipin -0.00579764
PTHLH parathyroid hormone-like hormone -0.00579671
FMOD fibromodulin -0.00579324
CEP55 centrosomal protein 55kDa -0.00578557
HACD3 3-hydroxyacyl-CoA dehydratase 3 -0.00578245
PTPRE protein tyrosine phosphatase, receptor type, E -0.00576797
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.0057633
NBPF10 neuroblastoma breakpoint family, member 10 -0.00576302
SLIT2 slit homolog 2 (Drosophila) -0.00574318
U2AF1 U2 small nuclear RNA auxiliary factor 1 -0.00572939
GUSBP3 glucuronidase, beta pseudogene 3 -0.00572871
PLAUR plasminogen activator, urokinase receptor -0.00570674
ACTC1 actin, alpha, cardiac muscle 1 -0.00569702
GPM6A glycoprotein M6A -0.00568645
HOMER3 homer scaffolding protein 3 -0.00568444
TGFB1 transforming growth factor, beta 1 -0.00567741
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.00567595
SPRY2 sprouty homolog 2 (Drosophila) -0.00567187
CNTN1 contactin 1 -0.00566449
IGFBP5 insulin-like growth factor binding protein 5 -0.00565533
PI3 peptidase inhibitor 3, skin-derived -0.00564475
KANK1 KN motif and ankyrin repeat domains 1 -0.00563788
LPP LIM domain containing preferred translocation partner in lipoma -0.00563774
DLG1 discs, large homolog 1 (Drosophila) -0.00563501
FBXW12 F-box and WD repeat domain containing 12 -0.00563346
KLF3-AS1 KLF3 antisense RNA 1 -0.00562667
SVIL supervillin -0.00561246
SYT17 synaptotagmin XVII -0.0056079
TENT5A terminal nucleotidyltransferase 5A -0.00560309
MELK maternal embryonic leucine zipper kinase -0.00558848
KMT2A lysine (K)-specific methyltransferase 2A -0.00558748
GPX2 glutathione peroxidase 2 -0.00558192
ASPH aspartate beta-hydroxylase -0.00558078
MFSD10 major facilitator superfamily domain containing 10 -0.00557704
SOGA1 suppressor of glucose, autophagy associated 1 -0.00557011
JUP junction plakoglobin -0.00555974
CBX6 chromobox homolog 6 -0.00553922
STC2 stanniocalcin 2 -0.00552746
KRT18 keratin 18, type I -0.00552601
ABAT 4-aminobutyrate aminotransferase -0.00552229
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00552219
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.00552027
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00551825
KRT13 keratin 13, type I -0.00551564
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.00550716
KCTD12 potassium channel tetramerization domain containing 12 -0.0054993
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00549831
CLIP3 CAP-GLY domain containing linker protein 3 -0.00549507
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 -0.00547657
MED1 mediator complex subunit 1 -0.00546661
NOTCH2 notch 2 -0.00546634
COL14A1 collagen, type XIV, alpha 1 -0.00545648
TENM1 teneurin transmembrane protein 1 -0.00542667
NKTR natural killer cell triggering receptor -0.00539241
DOCK9 dedicator of cytokinesis 9 -0.00536157
PCDH9 protocadherin 9 -0.00534889
GRAMD1B GRAM domain containing 1B -0.00534806
CTNND2 catenin (cadherin-associated protein), delta 2 -0.00534628
FOCAD focadhesin -0.00534204
CLDND1 claudin domain containing 1 -0.00534104
S100A11 S100 calcium binding protein A11 -0.005334
CANX calnexin -0.00532542
MAN2A1 mannosidase, alpha, class 2A, member 1 -0.00532419
LIMCH1 LIM and calponin homology domains 1 -0.00532054
HELZ helicase with zinc finger -0.00530651
ANK2 ankyrin 2, neuronal -0.00529732
SPRR1B small proline-rich protein 1B -0.00529473
ADCY9 adenylate cyclase 9 -0.00527974
EPHB2 EPH receptor B2 -0.00527933
IGFBP6 insulin-like growth factor binding protein 6 -0.00526445
SLC25A24 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24 -0.00525931
PDZD2 PDZ domain containing 2 -0.0052572