GFI1B Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description growth factor independent 1B transcription repressor|This gene encodes a zinc-finger containing transcriptional regulator that is primarily expressed in cells of hematopoietic lineage. The encoded protein complexes with numerous other transcriptional regulatory proteins including GATA-1, runt-related transcription factor 1 and histone deacetylases to control expression of genes involved in the development and maturation of erythrocytes and megakaryocytes. Mutations in this gene are the cause of the autosomal dominant platelet disorder, platelet-type bleeding disorder-17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] (NCBI Entrez Gene Database, 8328)
External Link http://www.ncbi.nlm.nih.gov/gene/8328
Similar Terms
Downloads & Tools

Genes

76 interacting proteins for GFI1B from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ACTN1 actinin, alpha 1
AES amino-terminal enhancer of split
AGPAT6 1-acylglycerol-3-phosphate O-acyltransferase 6
AGRN agrin
AJUBA ajuba LIM protein
ANKS3 ankyrin repeat and sterile alpha motif domain containing 3
ATXN2 ataxin 2
BECN1 beclin 1, autophagy related
BEGAIN brain-enriched guanylate kinase-associated
BEND5 BEN domain containing 5
BRCA1 breast cancer 1, early onset
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
CCDC136 coiled-coil domain containing 136
CCDC85B coiled-coil domain containing 85B
CENPB centromere protein B, 80kDa
CENPJ centromere protein J
COPS5 COP9 signalosome subunit 5
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DTNA dystrobrevin, alpha
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
EGFL7 EGF-like-domain, multiple 7
EHMT2 euchromatic histone-lysine N-methyltransferase 2
FBLN1 fibulin 1
FBLN5 fibulin 5
GRIP2 glutamate receptor interacting protein 2
GRN granulin
HDAC2 histone deacetylase 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSPG2 heparan sulfate proteoglycan 2
IFFO1 intermediate filament family orphan 1
JAG2 jagged 2
KALRN kalirin, RhoGEF kinase
KDM1A lysine (K)-specific demethylase 1A
KIF17 kinesin family member 17
LAMB1 laminin, beta 1
LTBP4 latent transforming growth factor beta binding protein 4
LZTS2 leucine zipper, putative tumor suppressor 2
MATR3 matrin 3
MEGF6 multiple EGF-like-domains 6
MEGF8 multiple EGF-like-domains 8
MID2 midline 2
MON1A MON1 secretory trafficking family member A
MYH14 myosin, heavy chain 14, non-muscle
NELL1 NEL-like 1 (chicken)
NELL2 NEL-like 2 (chicken)
NOTCH1 notch 1
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM5 PDZ and LIM domain 5
PDZD4 PDZ domain containing 4
PHC2 polyhomeotic homolog 2 (Drosophila)
PICK1 protein interacting with PRKCA 1
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
RAB11FIP4 RAB11 family interacting protein 4 (class II)
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RCOR1 REST corepressor 1
RINT1 RAD50 interactor 1
RNF31 ring finger protein 31
RUNDC3A RUN domain containing 3A
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TMF1 TATA element modulatory factor 1
TNS2 tensin 2
TRAF1 TNF receptor-associated factor 1
TRIM27 tripartite motif containing 27
TRIP6 thyroid hormone receptor interactor 6
TSPYL2 TSPY-like 2
TXNDC11 thioredoxin domain containing 11
USHBP1 Usher syndrome 1C binding protein 1
VSNL1 visinin-like 1
ZNRD1 zinc ribbon domain containing 1
ZNRF3 zinc and ring finger 3