GGA3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description golgi-associated, gamma adaptin ear containing, ARF binding protein 3|This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010] (NCBI Entrez Gene Database, 23163)
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38 interacting proteins for GGA3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AFTPH aftiphilin
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ARF1 ADP-ribosylation factor 1
ARF3 ADP-ribosylation factor 3
ARF6 ADP-ribosylation factor 6
BACE1 beta-site APP-cleaving enzyme 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CLINT1 clathrin interactor 1
CLTA clathrin, light chain A
CLTB clathrin, light chain B
CLTC clathrin, heavy chain (Hc)
COPA coatomer protein complex, subunit alpha
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSNK2A1 casein kinase 2, alpha 1 polypeptide
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
IGF2R insulin-like growth factor 2 receptor
LAPTM5 lysosomal protein transmembrane 5
M6PR mannose-6-phosphate receptor (cation dependent)
MET MET proto-oncogene, receptor tyrosine kinase
MON2 MON2 homolog (S. cerevisiae)
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
PACS1 phosphofurin acidic cluster sorting protein 1
RAB5A RAB5A, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RNF11 ring finger protein 11
RPS27A ribosomal protein S27a
SORT1 sortilin 1
STAB1 stabilin 1
SYNRG synergin, gamma
TGOLN2 trans-golgi network protein 2
TOLLIP toll interacting protein
TSG101 tumor susceptibility 101
UBB ubiquitin B
UBC ubiquitin C
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)