GGCT Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description gamma-glutamylcyclotransferase|The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] (NCBI Entrez Gene Database, 79017)
External Link http://www.ncbi.nlm.nih.gov/gene/79017
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79 interacting proteins for GGCT from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
A2ML1 alpha-2-macroglobulin-like 1
AHNAK AHNAK nucleoprotein
ANO5 anoctamin 5
ANXA1 annexin A1
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APP amyloid beta (A4) precursor protein
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C1ORF35 chromosome 1 open reading frame 35
CCDC85B coiled-coil domain containing 85B
CCDC85C coiled-coil domain containing 85C
CPVL carboxypeptidase, vitellogenic-like
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CSNK2B casein kinase 2, beta polypeptide
CSTA cystatin A (stefin A)
CTSD cathepsin D
DDB1 damage-specific DNA binding protein 1, 127kDa
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DOCK7 dedicator of cytokinesis 7
DVL1 dishevelled segment polarity protein 1
DVL2 dishevelled segment polarity protein 2
DVL3 dishevelled segment polarity protein 3
EGFR epidermal growth factor receptor
ERRFI1 ERBB receptor feedback inhibitor 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GDI2 GDP dissociation inhibitor 2
GPS1 G protein pathway suppressor 1
GRB2 growth factor receptor-bound protein 2
HECW2 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
HIST1H4F histone cluster 1, H4f
HSPA1L heat shock 70kDa protein 1-like
HSPA2 heat shock 70kDa protein 2
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
KCMF1 potassium channel modulatory factor 1
LRCH2 leucine-rich repeats and calponin homology (CH) domain containing 2
MCM7 minichromosome maintenance complex component 7
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NELL1 NEL-like 1 (chicken)
PARD3 par-3 family cell polarity regulator
PCBP1 poly(rC) binding protein 1
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRICKLE1 prickle homolog 1 (Drosophila)
PRICKLE3 prickle homolog 3 (Drosophila)
PTOV1 prostate tumor overexpressed 1
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
RASSF7 Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
RBBP4 retinoblastoma binding protein 4
RPS18 ribosomal protein S18
RPS4X ribosomal protein S4, X-linked
S100A14 S100 calcium binding protein A14
S100A7 S100 calcium binding protein A7
SAPCD2 suppressor APC domain containing 2
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMR3B submaxillary gland androgen regulated protein 3B
SNAP29 synaptosomal-associated protein, 29kDa
SPRR2E small proline-rich protein 2E
SRRM2 serine/arginine repetitive matrix 2
SUSD1 sushi domain containing 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TP53BP2 tumor protein p53 binding protein 2
TUBA1A tubulin, alpha 1a
TUFM Tu translation elongation factor, mitochondrial
UBASH3B ubiquitin associated and SH3 domain containing B
UBC ubiquitin C
UBE4B ubiquitination factor E4B
USP9X ubiquitin specific peptidase 9, X-linked
VANGL1 VANGL planar cell polarity protein 1