GIPC1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description GIPC PDZ domain containing family, member 1|GIPC1 is a scaffolding protein that regulates cell surface receptor expression and trafficking (Lee et al., 2008 [PubMed 18775991]).[supplied by OMIM, Apr 2009] (NCBI Entrez Gene Database, 10755)
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Genes

309 genes differentially expressed following the GIPC1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SIGLECL1 SIGLEC family like 1 2.77349
MYL10 myosin, light chain 10, regulatory 2.77349
XKR3 XK, Kell blood group complex subunit-related family, member 3 2.77349
MYEOV myeloma overexpressed 2.77349
SPRR1B small proline-rich protein 1B 2.77349
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 2.77349
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 2.77349
AVPR2 arginine vasopressin receptor 2 2.77349
SFTPB surfactant protein B 2.77349
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 2.77349
ASPA aspartoacylase 2.77349
DSG3 desmoglein 3 2.77349
CEP295NL CEP295 N-terminal like 2.77349
LILRB5 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 2.77349
SIGLEC7 sialic acid binding Ig-like lectin 7 2.77349
OLFM4 olfactomedin 4 2.77349
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 2.77349
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 2.77349
OR51M1 olfactory receptor, family 51, subfamily M, member 1 2.77349
OR2AJ1 olfactory receptor, family 2, subfamily AJ, member 1 2.77349
FIMP1 fertilization-influencing membrane protein 1 2.77349
ATOH1 atonal homolog 1 (Drosophila) 2.77349
TAS2R10 taste receptor, type 2, member 10 2.77349
VCX variable charge, X-linked 2.77349
THSD1 thrombospondin, type I, domain containing 1 2.77349
SP9 Sp9 transcription factor 2.77349
RAX2 retina and anterior neural fold homeobox 2 2.77349
RPEL1 ribulose-5-phosphate-3-epimerase-like 1 2.77349
NMUR2 neuromedin U receptor 2 2.77349
PNOC prepronociceptin 2.77349
S100A1 S100 calcium binding protein A1 2.77349
SPATA31C2 SPATA31 subfamily C, member 2 2.77349
RGPD3 RANBP2-like and GRIP domain containing 3 2.77349
RHCG Rh family, C glycoprotein 2.77349
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2 2.77349
LACTBL1 lactamase, beta-like 1 2.77349
ANKK1 ankyrin repeat and kinase domain containing 1 2.77349
GPR35 G protein-coupled receptor 35 2.77349
GNG13 guanine nucleotide binding protein (G protein), gamma 13 2.77349
OR2J3 olfactory receptor, family 2, subfamily J, member 3 2.77349
FOXR1 forkhead box R1 2.77349
GJB3 gap junction protein, beta 3, 31kDa 2.77349
KLRF2 killer cell lectin-like receptor subfamily F, member 2 2.77349
SLC22A16 solute carrier family 22 (organic cation/carnitine transporter), member 16 2.77349
MCEMP1 mast cell-expressed membrane protein 1 2.77349
P2RY8 purinergic receptor P2Y, G-protein coupled, 8 2.77349
GJD2 gap junction protein, delta 2, 36kDa 2.77349
EXOC3L4 exocyst complex component 3-like 4 2.77349
GJA4 gap junction protein, alpha 4, 37kDa 2.77349
HLX H2.0-like homeobox 2.77349
RLBP1 retinaldehyde binding protein 1 2.77349
RAB44 RAB44, member RAS oncogene family 2.77349
OVOL3 ovo-like zinc finger 3 2.77349
TLR6 toll-like receptor 6 2.77349
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4 2.77349
CLIP4 CAP-GLY domain containing linker protein family, member 4 2.77349
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.77349
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 2.77349
C12ORF54 chromosome 12 open reading frame 54 2.77349
WDR38 WD repeat domain 38 2.77349
INHBC inhibin, beta C 2.77349
LURAP1L leucine rich adaptor protein 1-like 2.77349
GLUD2 glutamate dehydrogenase 2 2.77349
PRODH2 proline dehydrogenase (oxidase) 2 2.77349
SLC35G5 solute carrier family 35, member G5 2.77349
GPR132 G protein-coupled receptor 132 2.77349
DDN dendrin 2.77349
IL5RA interleukin 5 receptor, alpha 2.77349
SLC25A45 solute carrier family 25, member 45 2.77349
ACE2 angiotensin I converting enzyme 2 2.77349
FGL2 fibrinogen-like 2 2.77349
CX3CL1 chemokine (C-X3-C motif) ligand 1 2.77349
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 2.77349
NKAPL NFKB activating protein-like 2.77349
VTN vitronectin 2.77349
ALG10B ALG10B, alpha-1,2-glucosyltransferase 2.77349
SCGN secretagogin, EF-hand calcium binding protein 2.77349
SAMD11 sterile alpha motif domain containing 11 2.77349
TAS1R1 taste receptor, type 1, member 1 2.77349
THAP10 THAP domain containing 10 2.77349
SPATA31F1 SPATA31 subfamily F member 1 2.77349
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 2.77349
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 2.77349
SMIM45 small integral membrane protein 45 2.77349
C2CD4B C2 calcium-dependent domain containing 4B 2.77349
PCDHGA4 protocadherin gamma subfamily A, 4 2.77349
MUCL1 mucin-like 1 2.77349
NUPR1 nuclear protein, transcriptional regulator, 1 2.77349
MUC15 mucin 15, cell surface associated 2.77349
CIMAP1B ciliary microtubule associated protein 1B 2.77349
C8ORF90 chromosome 8 open reading frame 90 2.77349
OR52P1 olfactory receptor family 52 subfamily P member 1 (gene/pseudogene) 2.77349
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 2.77349
H2BW2 H2B.W histone 2 2.77349
AQP8 aquaporin 8 2.77349
GLOD5 glyoxalase domain containing 5 2.77349
ADAMDEC1 ADAM-like, decysin 1 2.77349
PEAK3 PEAK family member 3 2.77349
RNASE10 ribonuclease, RNase A family, 10 (non-active) 2.77349
GML glycosylphosphatidylinositol anchored molecule like 2.77349
ADAM7 ADAM metallopeptidase domain 7 2.77349
BSPH1 binder of sperm protein homolog 1 2.77349
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 2.77349
SPDYE8 speedy/RINGO cell cycle regulator family member E8 2.77349
MEPE matrix extracellular phosphoglycoprotein 2.77349
CNGB1 cyclic nucleotide gated channel beta 1 2.77349
GJC2 gap junction protein, gamma 2, 47kDa 2.77349
GOLGA8N golgin A8 family, member N 2.77349
LRRC24 leucine rich repeat containing 24 2.77349
CIMIP2A ciliary microtubule inner protein 2A 2.77349
CFB complement factor B 2.77349
POU4F1 POU class 4 homeobox 1 2.77349
RASA4 RAS p21 protein activator 4 2.77349
DEFA5 defensin, alpha 5, Paneth cell-specific 2.77349
SYNGR4 synaptogyrin 4 2.77349
TAGAP T-cell activation RhoGTPase activating protein 2.77349
LHX9 LIM homeobox 9 2.77349
LHX5 LIM homeobox 5 2.77349
QRFP pyroglutamylated RFamide peptide 2.77349
NKX6-1 NK6 homeobox 1 2.77349
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 2.77349
SPEM2 SPEM family member 2 2.77349
CLDN34 claudin 34 2.77349
MT3 metallothionein 3 2.77349
DNAH8 dynein, axonemal, heavy chain 8 2.77349
TRAF3IP3 TRAF3 interacting protein 3 2.77349
SLC38A11 solute carrier family 38, member 11 2.77349
CHIA chitinase, acidic 2.77349
FRMPD4 FERM and PDZ domain containing 4 2.77349
TMEM156 transmembrane protein 156 2.77349
C10ORF90 chromosome 10 open reading frame 90 2.77349
PTCRA pre T-cell antigen receptor alpha 2.77349
OR52I2 olfactory receptor, family 52, subfamily I, member 2 2.77349
ASCL3 achaete-scute family bHLH transcription factor 3 2.77349
SFTPA1 surfactant protein A1 2.77349
BTBD19 BTB (POZ) domain containing 19 2.77349
FAM81B family with sequence similarity 81, member B 2.77349
TPH1 tryptophan hydroxylase 1 2.77349
NPR3 natriuretic peptide receptor 3 2.77349
RBP4 retinol binding protein 4, plasma 2.77349
PHF24 PHD finger protein 24 2.77349
ISLR2 immunoglobulin superfamily containing leucine-rich repeat 2 2.77349
H2BC1 H2B clustered histone 1 2.77349
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 2.77349
SPRN shadow of prion protein homolog (zebrafish) 2.77349
NGB neuroglobin 2.77349
APOD apolipoprotein D 2.77349
GK3 glycerol kinase 3 2.77349
VAX2 ventral anterior homeobox 2 2.77349
TBXT T-box transcription factor T 2.77349
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 2.77349
H2BC17 H2B clustered histone 17 2.77349
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 2.77349
FIGLA folliculogenesis specific basic helix-loop-helix 2.77349
AGR2 anterior gradient 2 2.77349
HTD2 hydroxyacyl-thioester dehydratase type 2 2.77349
PLAAT4 phospholipase A and acyltransferase 4 2.77349
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 2.77349
SPNS3 spinster homolog 3 (Drosophila) 2.77349
MAEL maelstrom spermatogenic transposon silencer 2.77349
TBC1D28 TBC1 domain family, member 28 2.77349
TRIM29 tripartite motif containing 29 2.77349
RGS11 regulator of G-protein signaling 11 2.77349
SOCS4 suppressor of cytokine signaling 4 2.76626
CALCA calcitonin-related polypeptide alpha 2.69671
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.69671
GPR20 G protein-coupled receptor 20 2.69671
ABLIM3 actin binding LIM protein family, member 3 2.69671
GPR19 G protein-coupled receptor 19 2.63609
KIAA0825 KIAA0825 2.6217
XBP1 X-box binding protein 1 2.58202
ZNF419 zinc finger protein 419 2.56391
CHMP2A charged multivesicular body protein 2A 2.55277
COLEC12 collectin sub-family member 12 2.53587
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 2.46288
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 2.4579
MED23 mediator complex subunit 23 2.42441
RPP21 ribonuclease P/MRP 21kDa subunit 2.41592
RDH13 retinol dehydrogenase 13 (all-trans/9-cis) 2.41592
CLDN7 claudin 7 2.39724
FRAS1 Fraser extracellular matrix complex subunit 1 2.38763
CELF5 CUGBP, Elav-like family member 5 2.35666
ESPN espin 2.34049
SGSM1 small G protein signaling modulator 1 2.32011
RNASET2 ribonuclease T2 2.32011
ARHGAP28 Rho GTPase activating protein 28 2.31382
TOR1AIP1 torsin A interacting protein 1 2.31141
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 2.3068
COLEC11 collectin sub-family member 11 2.29991
SIRT7 sirtuin 7 2.26937
ZNF726 zinc finger protein 726 2.25616
ATAD3B ATPase family, AAA domain containing 3B 2.25527
HS1BP3 HCLS1 binding protein 3 2.23835
ERGIC3 ERGIC and golgi 3 2.23219
NIPAL1 NIPA-like domain containing 1 2.2144
ARFIP2 ADP-ribosylation factor interacting protein 2 2.19049
MAN1B1 mannosidase, alpha, class 1B, member 1 2.17363
TBC1D22B TBC1 domain family, member 22B 2.17363
SP8 Sp8 transcription factor 2.16701
CCDC144A coiled-coil domain containing 144A 2.1664
EDNRA endothelin receptor type A 2.16122
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 2.15538
EMID1 EMI domain containing 1 2.15003
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1 2.15003
PPME1 protein phosphatase methylesterase 1 2.15003
KCNIP1 Kv channel interacting protein 1 2.10289
CNTNAP3 contactin associated protein-like 3 2.10226
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 2.10174
AKAP8 A kinase (PRKA) anchor protein 8 2.09164
GADD45A growth arrest and DNA-damage-inducible, alpha 2.06862
EML1 echinoderm microtubule associated protein like 1 2.06001
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit 2.05117
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 2.04425
COLGALT2 collagen beta(1-O)galactosyltransferase 2 2.03415
USF3 upstream transcription factor family member 3 2.03024
ATPSCKMT ATP synthase c subunit lysine N-methyltransferase 2.02255
COMTD1 catechol-O-methyltransferase domain containing 1 2.00908
TAFA4 TAFA chemokine like family member 4 2.00908

decreased expression

Symbol Name Standardized Value
MDFIC2 MyoD family inhibitor domain containing 2 -2.77349
GPR55 G protein-coupled receptor 55 -2.77349
ALOX15 arachidonate 15-lipoxygenase -2.77349
HES7 hes family bHLH transcription factor 7 -2.77349
PDE7B phosphodiesterase 7B -2.77349
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 -2.77349
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like -2.77349
GUCY2F guanylate cyclase 2F, retinal -2.77349
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta -2.77349
RASSF6 Ras association (RalGDS/AF-6) domain family member 6 -2.77349
SCG2 secretogranin II -2.77349
NAPSA napsin A aspartic peptidase -2.77349
UPK3B uroplakin 3B -2.77349
LY6H lymphocyte antigen 6 complex, locus H -2.77349
TUBA4A tubulin, alpha 4a -2.77349
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent -2.77349
FAM186A family with sequence similarity 186, member A -2.77349
C1QL2 complement component 1, q subcomponent-like 2 -2.77349
MSX1 msh homeobox 1 -2.77349
TMIE transmembrane inner ear -2.77349
CAPN14 calpain 14 -2.77349
TAS2R5 taste receptor, type 2, member 5 -2.77349
LGALS4 lectin, galactoside-binding, soluble, 4 -2.77349
CAMK2B calcium/calmodulin-dependent protein kinase II beta -2.77349
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 -2.77349
CSPG4 chondroitin sulfate proteoglycan 4 -2.77349
CHIT1 chitinase 1 (chitotriosidase) -2.77349
COL17A1 collagen, type XVII, alpha 1 -2.77349
PCDH20 protocadherin 20 -2.77349
BAHCC1 BAH domain and coiled-coil containing 1 -2.77349
CIMAP2 ciliary microtubule associated protein 2 -2.77349
KIF26B kinesin family member 26B -2.77349
NACA2 nascent polypeptide-associated complex alpha subunit 2 -2.77349
ZMPSTE24 zinc metallopeptidase STE24 -2.73463
KIRREL2 kin of IRRE like 2 (Drosophila) -2.73157
NOTCH4 notch 4 -2.73157
GIPC1 GIPC PDZ domain containing family, member 1 -2.69448
GJD3 gap junction protein, delta 3, 31.9kDa -2.64366
TRIB1 tribbles pseudokinase 1 -2.58202
NPIPB6 nuclear pore complex interacting protein family, member B6 -2.55775
CCDC152 coiled-coil domain containing 152 -2.55277
PLAA phospholipase A2-activating protein -2.55277
PER2 period circadian clock 2 -2.52888
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 -2.50452
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -2.46024
CYB561 cytochrome b561 -2.44777
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -2.40079
DESI2 desumoylating isopeptidase 2 -2.39724
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.39153
GORAB golgin, RAB6-interacting -2.38039
RTL8C retrotransposon Gag like 8C -2.33993
GUF1 GUF1 GTPase homolog (S. cerevisiae) -2.32011
ACOT2 acyl-CoA thioesterase 2 -2.31141
NSRP1 nuclear speckle splicing regulatory protein 1 -2.31141
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -2.3068
GRM7 glutamate receptor, metabotropic 7 -2.29991
DEUP1 deuterosome assembly protein 1 -2.29933
CD7 CD7 molecule -2.29933
ZNF404 zinc finger protein 404 -2.24935
NLRP2 NLR family, pyrin domain containing 2 -2.2425
FAM3C family with sequence similarity 3, member C -2.23741
ZNF638 zinc finger protein 638 -2.23532
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 -2.23219
C4ORF46 chromosome 4 open reading frame 46 -2.18232
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.17363
FAM219A family with sequence similarity 219, member A -2.15804
CMC2 C-x(9)-C motif containing 2 -2.15804
NAGK N-acetylglucosamine kinase -2.15538
KCNK7 potassium channel, two pore domain subfamily K, member 7 -2.15003
FAM20C family with sequence similarity 20, member C -2.15003
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 -2.12511
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) -2.11655
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -2.11655
CXCL5 chemokine (C-X-C motif) ligand 5 -2.11655
IZUMO1 izumo sperm-egg fusion 1 -2.11655
NPIPA7 nuclear pore complex interacting protein family, member A7 -2.11655
PLAUR plasminogen activator, urokinase receptor -2.10289
IGSF11 immunoglobulin superfamily, member 11 -2.09418
USP19 ubiquitin specific peptidase 19 -2.08445
UBAC2 UBA domain containing 2 -2.07766
BRPF1 bromodomain and PHD finger containing, 1 -2.07287
MTRF1 mitochondrial translational release factor 1 -2.06001
INO80D INO80 complex subunit D -2.05795
DCLRE1B DNA cross-link repair 1B -2.05117
ADGRL3 adhesion G protein-coupled receptor L3 -2.03686
MATCAP2 microtubule associated tyrosine carboxypeptidase 2 -2.03509
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -2.03509
HGS hepatocyte growth factor-regulated tyrosine kinase substrate -2.03415
AGMAT agmatine ureohydrolase (agmatinase) -2.03415
OXNAD1 oxidoreductase NAD-binding domain containing 1 -2.03032
CCN2 cellular communication network factor 2 -2.01296