| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | galactosidase, alpha|This gene encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2717) |
| External Link | https://ncbi.nlm.nih.gov/gene/2717 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the GLA gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0237574 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0190968 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.016152 |
| XPO7 | exportin 7 | 0.0155391 |
| STK10 | serine/threonine kinase 10 | 0.0149612 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0147975 |
| S100A7 | S100 calcium binding protein A7 | 0.0127554 |
| DIPK1A | divergent protein kinase domain 1A | 0.0125931 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0121739 |
| CD99 | CD99 molecule | 0.0117538 |
| KRT14 | keratin 14, type I | 0.0113967 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0111876 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.0109318 |
| NID1 | nidogen 1 | 0.0107528 |
| SRPX | sushi-repeat containing protein, X-linked | 0.0106207 |
| EMX2 | empty spiracles homeobox 2 | 0.0103434 |
| GSTA4 | glutathione S-transferase alpha 4 | 0.00998542 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00988162 |
| MAGEA3 | melanoma antigen family A3 | 0.00980908 |
| DSP | desmoplakin | 0.00978251 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00959207 |
| ADD3 | adducin 3 (gamma) | 0.00941464 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00938934 |
| S100A10 | S100 calcium binding protein A10 | 0.00938516 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.00930391 |
| RHCG | Rh family, C glycoprotein | 0.00889081 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00888454 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00884144 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.00867816 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 | 0.00867211 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00866903 |
| PODXL | podocalyxin-like | 0.00860755 |
| PLS3 | plastin 3 | 0.00858087 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.00856984 |
| STC1 | stanniocalcin 1 | 0.00849333 |
| DAD1 | defender against cell death 1 | 0.00846427 |
| LTA4H | leukotriene A4 hydrolase | 0.00846321 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.00845297 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 | 0.0083874 |
| AUTS2 | autism susceptibility candidate 2 | 0.00833735 |
| BAX | BCL2-associated X protein | 0.0083178 |
| FCGBP | Fc fragment of IgG binding protein | 0.00824413 |
| CRYBG1 | crystallin beta-gamma domain containing 1 | 0.00823118 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 | 0.00820724 |
| CHEK1 | checkpoint kinase 1 | 0.00820256 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0081699 |
| SDC1 | syndecan 1 | 0.0080946 |
| MAGEA12 | melanoma antigen family A12 | 0.00807986 |
| S100A14 | S100 calcium binding protein A14 | 0.00807132 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.00797278 |
| MOXD1 | monooxygenase, DBH-like 1 | 0.00792487 |
| TYRP1 | tyrosinase-related protein 1 | 0.00785617 |
| SYNE3 | spectrin repeat containing, nuclear envelope family member 3 | 0.00784951 |
| SH3YL1 | SH3 and SYLF domain containing 1 | 0.00777654 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00767952 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 0.00766913 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.00764302 |
| SFRP1 | secreted frizzled-related protein 1 | 0.00762851 |
| CA12 | carbonic anhydrase XII | 0.00758194 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00746244 |
| AKR7A2 | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 0.00744502 |
| ANXA6 | annexin A6 | 0.00744173 |
| PEG10 | paternally expressed 10 | 0.00743754 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00741372 |
| WDR26 | WD repeat domain 26 | 0.00740324 |
| KRT16 | keratin 16, type I | 0.00737775 |
| SMC6 | structural maintenance of chromosomes 6 | 0.007354 |
| GPHN | gephyrin | 0.00733549 |
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.00732654 |
| KLK5 | kallikrein-related peptidase 5 | 0.00730822 |
| NRN1 | neuritin 1 | 0.00730161 |
| ACOX2 | acyl-CoA oxidase 2, branched chain | 0.00724698 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.00720867 |
| DSG1 | desmoglein 1 | 0.00711311 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.00708757 |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.00708474 |
| TJP2 | tight junction protein 2 | 0.00705959 |
| RORA | RAR-related orphan receptor A | 0.00700128 |
| RNF167 | ring finger protein 167 | 0.00698705 |
| KRT1 | keratin 1, type II | 0.00698287 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00696214 |
| CLDND1 | claudin domain containing 1 | 0.00692962 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M | 0.00688359 |
| PITX3 | paired-like homeodomain 3 | 0.00687506 |
| CALML3 | calmodulin-like 3 | 0.00681877 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.00681447 |
| LRRC17 | leucine rich repeat containing 17 | 0.00679833 |
| SH2B3 | SH2B adaptor protein 3 | 0.00676669 |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.00674284 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.00674138 |
| EFNA1 | ephrin-A1 | 0.00673093 |
| CLCA2 | chloride channel accessory 2 | 0.0067045 |
| TUBB2A | tubulin, beta 2A class IIa | 0.00669808 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | 0.00663396 |
| SPRY4 | sprouty homolog 4 (Drosophila) | 0.00659302 |
| FERMT1 | fermitin family member 1 | 0.00657551 |
| SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporter), member 1 | 0.00657416 |
| NVL | nuclear VCP-like | 0.00654567 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0065273 |
| CTSV | cathepsin V | 0.00650021 |
| ADIPOR1 | adiponectin receptor 1 | 0.0064883 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.00646983 |
| IL27RA | interleukin 27 receptor, alpha | 0.00644574 |
| BCHE | butyrylcholinesterase | 0.00642306 |
| AOX1 | aldehyde oxidase 1 | 0.00641715 |
| EXOC5 | exocyst complex component 5 | 0.00641353 |
| KRT15 | keratin 15, type I | 0.0064041 |
| KRT5 | keratin 5, type II | 0.00638776 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00631683 |
| DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) | 0.00629194 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00626896 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | 0.00626507 |
| HDGF | hepatoma-derived growth factor | 0.00625728 |
| GAS6 | growth arrest-specific 6 | 0.00619095 |
| KRT6B | keratin 6B, type II | 0.00618802 |
| GCH1 | GTP cyclohydrolase 1 | 0.00617725 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 0.00617292 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.00617128 |
| RGCC | regulator of cell cycle | 0.00616622 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | 0.00616076 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | 0.00614296 |
| CLIC3 | chloride intracellular channel 3 | 0.00614277 |
| SNAI2 | snail family zinc finger 2 | 0.00613875 |
| AP2S1 | adaptor-related protein complex 2, sigma 1 subunit | 0.00613526 |
| ASS1 | argininosuccinate synthase 1 | 0.00612273 |
| IFITM2 | interferon induced transmembrane protein 2 | 0.00610595 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | 0.00608768 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.00607044 |
| LY6D | lymphocyte antigen 6 complex, locus D | 0.00606722 |
| CLCA1 | chloride channel accessory 1 | 0.00604277 |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 | 0.00603207 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | 0.00602217 |
| L1TD1 | LINE-1 type transposase domain containing 1 | 0.00602176 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | 0.00598006 |
| ELOVL4 | ELOVL fatty acid elongase 4 | 0.00597748 |
| RPL36AL | ribosomal protein L36a-like | 0.0059307 |
| PRDX6 | peroxiredoxin 6 | 0.00592353 |
| MME | membrane metallo-endopeptidase | 0.0059174 |
| DSC1 | desmocollin 1 | 0.00589391 |
| DENND2B | DENN domain containing 2B | 0.00588443 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00586561 |
| UMOD | uromodulin | 0.00585674 |
| NELL2 | NEL-like 2 (chicken) | 0.00585012 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.00584042 |
| CAPRIN2 | caprin family member 2 | 0.00583269 |
| GYPC | glycophorin C (Gerbich blood group) | 0.00582158 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | 0.00582133 |
| GAS2 | growth arrest-specific 2 | 0.00581726 |
| PMCH | pro-melanin-concentrating hormone | 0.00580708 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00579969 |
| PDLIM2 | PDZ and LIM domain 2 (mystique) | 0.00579397 |
| USP18 | ubiquitin specific peptidase 18 | 0.00579153 |
| PRMT5 | protein arginine methyltransferase 5 | 0.00578265 |
| MEIS2 | Meis homeobox 2 | 0.00577472 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.00577115 |
| KLF6 | Kruppel-like factor 6 | 0.0057643 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F | 0.00576175 |
| TMCC2 | transmembrane and coiled-coil domain family 2 | 0.00576117 |
| ITGB7 | integrin, beta 7 | 0.00571567 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.00570532 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00570122 |
| GSTT1 | glutathione S-transferase theta 1 | 0.00569815 |
| CD81 | CD81 molecule | 0.00569724 |
| ZNF331 | zinc finger protein 331 | 0.00566651 |
| ESD | esterase D | 0.00566301 |
| NOTCH3 | notch 3 | 0.00566226 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00566204 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00563487 |
| LOR | loricrin | 0.00563442 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | 0.00561099 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.00560624 |
| PRKD3 | protein kinase D3 | 0.0056012 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.00558437 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.0055656 |
| NBEAL2 | neurobeachin-like 2 | 0.00555778 |
| CTAG2 | cancer/testis antigen 2 | 0.00555448 |
| FLI1 | Fli-1 proto-oncogene, ETS transcription factor | 0.00554692 |
| BDKRB1 | bradykinin receptor B1 | 0.00553827 |
| CES1 | carboxylesterase 1 | 0.00553458 |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 | 0.00552342 |
| LIG1 | ligase I, DNA, ATP-dependent | 0.00552291 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00551709 |
| THY1 | Thy-1 cell surface antigen | 0.00551234 |
| MAGEA11 | melanoma antigen family A11 | 0.00550039 |
| AHNAK | AHNAK nucleoprotein | 0.00549988 |
| COL16A1 | collagen, type XVI, alpha 1 | 0.00549202 |
| VSNL1 | visinin-like 1 | 0.00549189 |
| ITSN2 | intersectin 2 | 0.00548486 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00547283 |
| SPEN | spen family transcriptional repressor | 0.00547141 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00545515 |
| NPEPL1 | aminopeptidase-like 1 | 0.00545464 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.00544729 |
| OVGP1 | oviductal glycoprotein 1, 120kDa | 0.00542688 |
| WASHC4 | WASH complex subunit 4 | 0.00541822 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | 0.00539322 |
| GLRX5 | glutaredoxin 5 | 0.00537633 |
| TUBB2B | tubulin, beta 2B class IIb | 0.00535716 |
| DSC2 | desmocollin 2 | 0.00535393 |
| SCFD1 | sec1 family domain containing 1 | 0.00534723 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.00532746 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.00532485 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.00531791 |
| LYPD3 | LY6/PLAUR domain containing 3 | 0.00531642 |
| C3ORF14 | chromosome 3 open reading frame 14 | 0.00530244 |
| ABCA4 | ATP-binding cassette, sub-family A (ABC1), member 4 | 0.0052986 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00529452 |
| SPRR1B | small proline-rich protein 1B | 0.00529237 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00528932 |
| PLPP3 | phospholipid phosphatase 3 | 0.0052854 |
| HAS2 | hyaluronan synthase 2 | 0.00528198 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.00527417 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00527326 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.00526671 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.0052581 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.00525554 |
| KRT6A | keratin 6A, type II | 0.00525474 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00523997 |
| PYCARD | PYD and CARD domain containing | 0.005236 |
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.00522636 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | 0.0051997 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00517607 |
| RAB25 | RAB25, member RAS oncogene family | 0.00517386 |
| PEG3 | paternally expressed 3 | 0.00517347 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0051562 |
| MUC16 | mucin 16, cell surface associated | 0.00515375 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.00515139 |
| ANGPT2 | angiopoietin 2 | 0.00514903 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.00513747 |
| NEFM | neurofilament, medium polypeptide | 0.00513533 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.00512871 |
| CCNG1 | cyclin G1 | 0.00512345 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.00511656 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0051138 |
| INAVA | innate immunity activator | 0.00510896 |
| VRK3 | vaccinia related kinase 3 | 0.005091 |
| SELENBP1 | selenium binding protein 1 | 0.0050904 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) | 0.00508016 |
| TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.00506859 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 | 0.00505782 |
| FMO1 | flavin containing monooxygenase 1 | 0.0050486 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.00504576 |
| TMEM255A | transmembrane protein 255A | 0.00503979 |
| POLR3G | polymerase (RNA) III (DNA directed) polypeptide G (32kD) | 0.00503363 |
| PRKD1 | protein kinase D1 | 0.00502423 |
| RADX | RPA1 related single stranded DNA binding protein, X-linked | 0.00502285 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00501012 |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.00499837 |
| TAC1 | tachykinin, precursor 1 | 0.00499559 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LYZ | lysozyme | -0.0187694 |
| PCNA | proliferating cell nuclear antigen | -0.0142345 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.0142166 |
| NNMT | nicotinamide N-methyltransferase | -0.0138186 |
| TGM2 | transglutaminase 2 | -0.0134528 |
| XIC | X chromosome inactivation center | -0.0131221 |
| TSPAN13 | tetraspanin 13 | -0.0128794 |
| S100P | S100 calcium binding protein P | -0.0126203 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.0124246 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.0122009 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0121776 |
| AGR2 | anterior gradient 2 | -0.012172 |
| PROM1 | prominin 1 | -0.0120874 |
| ANXA3 | annexin A3 | -0.0118456 |
| DEFA4 | defensin, alpha 4, corticostatin | -0.0118288 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.0117301 |
| ATP9A | ATPase, class II, type 9A | -0.0113708 |
| TXNDC9 | thioredoxin domain containing 9 | -0.0113287 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 | -0.0113268 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -0.0111733 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.010755 |
| CYBB | cytochrome b-245, beta polypeptide | -0.0105151 |
| C1QA | complement component 1, q subcomponent, A chain | -0.0103994 |
| FUCA1 | fucosidase, alpha-L- 1, tissue | -0.0103019 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.0101312 |
| AHR | aryl hydrocarbon receptor | -0.01012 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0101054 |
| PHACTR2 | phosphatase and actin regulator 2 | -0.00997704 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 | -0.00991914 |
| EIF5A | eukaryotic translation initiation factor 5A | -0.00979801 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00976362 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00967587 |
| TPD52 | tumor protein D52 | -0.00964559 |
| STK39 | serine threonine kinase 39 | -0.00963396 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.00957861 |
| S100A4 | S100 calcium binding protein A4 | -0.00951437 |
| ALOX5 | arachidonate 5-lipoxygenase | -0.00943309 |
| MT1M | metallothionein 1M | -0.00941056 |
| KYNU | kynureninase | -0.00940791 |
| CP | ceruloplasmin (ferroxidase) | -0.00923118 |
| TOB1 | transducer of ERBB2, 1 | -0.0091971 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00907328 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.00906704 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -0.00904799 |
| ANXA1 | annexin A1 | -0.00896324 |
| RGS13 | regulator of G-protein signaling 13 | -0.00888449 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00886148 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00884232 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00884067 |
| MAP7 | microtubule-associated protein 7 | -0.00880096 |
| LTF | lactotransferrin | -0.00879427 |
| BIK | BCL2-interacting killer (apoptosis-inducing) | -0.0087912 |
| MMP7 | matrix metallopeptidase 7 | -0.00878486 |
| MMP9 | matrix metallopeptidase 9 | -0.00874482 |
| ACKR3 | atypical chemokine receptor 3 | -0.00872447 |
| C8ORF4 | chromosome 8 open reading frame 4 | -0.00872349 |
| CLC | Charcot-Leyden crystal galectin | -0.00867804 |
| KRT17 | keratin 17, type I | -0.00865188 |
| MGLL | monoglyceride lipase | -0.00863998 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -0.00863379 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | -0.00856725 |
| CUX1 | cut-like homeobox 1 | -0.00855 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00850251 |
| ZNF652 | zinc finger protein 652 | -0.00844112 |
| SRGN | serglycin | -0.00840942 |
| KIAA0100 | KIAA0100 | -0.00834542 |
| CSRP1 | cysteine and glycine-rich protein 1 | -0.00833564 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.00833117 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 | -0.00832361 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00828097 |
| PDLIM3 | PDZ and LIM domain 3 | -0.00827049 |
| HIST1H2BD | histone cluster 1, H2bd | -0.00824967 |
| TYROBP | TYRO protein tyrosine kinase binding protein | -0.00824047 |
| RND3 | Rho family GTPase 3 | -0.00816135 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -0.00813351 |
| ADAMDEC1 | ADAM-like, decysin 1 | -0.00812907 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00809726 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.00807335 |
| MANSC1 | MANSC domain containing 1 | -0.00806712 |
| IDO1 | indoleamine 2,3-dioxygenase 1 | -0.00801786 |
| GPX2 | glutathione peroxidase 2 | -0.00801465 |
| PRSS21 | protease, serine, 21 (testisin) | -0.00800374 |
| ANKMY2 | ankyrin repeat and MYND domain containing 2 | -0.00794646 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -0.00792339 |
| CD163 | CD163 molecule | -0.00785963 |
| LY75 | lymphocyte antigen 75 | -0.00784184 |
| DUSP3 | dual specificity phosphatase 3 | -0.00782649 |
| CLU | clusterin | -0.00781596 |
| C1QB | complement component 1, q subcomponent, B chain | -0.00780953 |
| CEACAM8 | carcinoembryonic antigen-related cell adhesion molecule 8 | -0.00777771 |
| SLPI | secretory leukocyte peptidase inhibitor | -0.00772614 |
| TRAPPC3 | trafficking protein particle complex 3 | -0.0077016 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | -0.00761948 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00752989 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.00752521 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G | -0.00731308 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00729485 |
| DAPK1 | death-associated protein kinase 1 | -0.00728987 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | -0.00728739 |
| COX7B | cytochrome c oxidase subunit VIIb | -0.00726237 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00724614 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.00723813 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | -0.00722843 |
| PLTP | phospholipid transfer protein | -0.00722179 |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | -0.00721601 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00721141 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.00718246 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00717809 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.00716699 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0071482 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00708067 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0070773 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -0.0070728 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.00704063 |
| UPK1B | uroplakin 1B | -0.00703339 |
| GUSBP3 | glucuronidase, beta pseudogene 3 | -0.00703312 |
| RFC5 | replication factor C (activator 1) 5, 36.5kDa | -0.007019 |
| MAPT | microtubule-associated protein tau | -0.0070106 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.00700091 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.00699 |
| APOD | apolipoprotein D | -0.0069783 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | -0.00693449 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.00688099 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00687162 |
| CPD | carboxypeptidase D | -0.00685979 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 | -0.00684986 |
| PDLIM5 | PDZ and LIM domain 5 | -0.00684026 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.00682127 |
| CTSL | cathepsin L | -0.00680895 |
| QKI | QKI, KH domain containing, RNA binding | -0.00680229 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00680079 |
| HIST1H2AE | histone cluster 1, H2ae | -0.00679692 |
| CAMP | cathelicidin antimicrobial peptide | -0.00679643 |
| FADS3 | fatty acid desaturase 3 | -0.00678209 |
| PFDN4 | prefoldin subunit 4 | -0.00677006 |
| PLBD1 | phospholipase B domain containing 1 | -0.00676055 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00675353 |
| VCAM1 | vascular cell adhesion molecule 1 | -0.00673901 |
| IL1R1 | interleukin 1 receptor, type I | -0.00672785 |
| TPD52L1 | tumor protein D52-like 1 | -0.00671774 |
| GGT1 | gamma-glutamyltransferase 1 | -0.00670301 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.00668362 |
| SCARB2 | scavenger receptor class B, member 2 | -0.00666522 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.00666378 |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit | -0.00666213 |
| IFT20 | intraflagellar transport 20 | -0.00665831 |
| MET | MET proto-oncogene, receptor tyrosine kinase | -0.00665535 |
| PMP22 | peripheral myelin protein 22 | -0.00664977 |
| AKAP7 | A kinase (PRKA) anchor protein 7 | -0.00661408 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.00661088 |
| SDC3 | syndecan 3 | -0.00660869 |
| MLXIP | MLX interacting protein | -0.00660561 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0066017 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.00659707 |
| CCNG2 | cyclin G2 | -0.00658147 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.00655433 |
| CPA3 | carboxypeptidase A3 (mast cell) | -0.00655071 |
| IL18 | interleukin 18 | -0.00652844 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | -0.00652817 |
| FOXF1 | forkhead box F1 | -0.00650402 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00650333 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | -0.00649335 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.0064809 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.00647771 |
| RTN2 | reticulon 2 | -0.00645969 |
| CRYAB | crystallin, alpha B | -0.00643553 |
| PLK2 | polo-like kinase 2 | -0.0064264 |
| IL6ST | interleukin 6 signal transducer | -0.00642039 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.00641229 |
| COX7A2 | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) | -0.00639882 |
| CFH | complement factor H | -0.00639795 |
| CYTL1 | cytokine-like 1 | -0.00635916 |
| CTSS | cathepsin S | -0.00635329 |
| SLC44A4 | solute carrier family 44, member 4 | -0.00634726 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | -0.00633066 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.00631135 |
| HAUS3 | HAUS augmin-like complex, subunit 3 | -0.00631014 |
| GLA | galactosidase, alpha | -0.00628943 |
| AXL | AXL receptor tyrosine kinase | -0.00627358 |
| PTER | phosphotriesterase related | -0.00627202 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.00626402 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.00626042 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00622854 |
| HSPA14 | heat shock 70kDa protein 14 | -0.00622253 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.006222 |
| MITF | microphthalmia-associated transcription factor | -0.00621634 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00621236 |
| PFKP | phosphofructokinase, platelet | -0.00620056 |
| COMMD3 | COMM domain containing 3 | -0.00617159 |
| PDE8B | phosphodiesterase 8B | -0.00616652 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00614882 |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | -0.00613891 |
| CUEDC1 | CUE domain containing 1 | -0.00613463 |
| GSN | gelsolin | -0.00613365 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.00612464 |
| FAM222B | family with sequence similarity 222, member B | -0.00611661 |
| NCALD | neurocalcin delta | -0.00610936 |
| PXDC1 | PX domain containing 1 | -0.00610663 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.0060995 |
| GOLM1 | golgi membrane protein 1 | -0.00608931 |
| ANKRD10 | ankyrin repeat domain 10 | -0.00607793 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 | -0.00607774 |
| CD38 | CD38 molecule | -0.00607426 |
| RIN2 | Ras and Rab interactor 2 | -0.00606343 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 | -0.00605001 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.00603406 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | -0.00602005 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.00599305 |
| ANXA4 | annexin A4 | -0.00597663 |
| TIMM8B | translocase of inner mitochondrial membrane 8 homolog B (yeast) | -0.00597434 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.00597027 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.00596448 |
| MYBPC1 | myosin binding protein C, slow type | -0.00594591 |
| CLGN | calmegin | -0.00594471 |
| FOXO1 | forkhead box O1 | -0.00593003 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 | -0.00592371 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | -0.00591762 |
| LPAR1 | lysophosphatidic acid receptor 1 | -0.00589976 |
| RGS1 | regulator of G-protein signaling 1 | -0.0058987 |
| MCOLN1 | mucolipin 1 | -0.00589585 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.00587346 |
| CADM1 | cell adhesion molecule 1 | -0.00586737 |
| TPSAB1 | tryptase alpha/beta 1 | -0.00585201 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00581404 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -0.00580818 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 | -0.00580106 |
| SEPHS2 | selenophosphate synthetase 2 | -0.00579982 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | -0.00579661 |
| ATP2B2 | ATPase, Ca++ transporting, plasma membrane 2 | -0.0057948 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00578783 |
| NAAA | N-acylethanolamine acid amidase | -0.00577772 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00576885 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00576601 |
| CIDEC | cell death-inducing DFFA-like effector c | -0.00576082 |
| PRKCB | protein kinase C, beta | -0.00573989 |
| GRSF1 | G-rich RNA sequence binding factor 1 | -0.0057359 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein | -0.00573164 |
| NMU | neuromedin U | -0.00571721 |
| GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 | -0.00571679 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | -0.0057142 |
| S100A12 | S100 calcium binding protein A12 | -0.005709 |
| NTS | neurotensin | -0.00570498 |
| CST3 | cystatin C | -0.00569501 |
| HAVCR1 | hepatitis A virus cellular receptor 1 | -0.00568827 |
| DCK | deoxycytidine kinase | -0.00568773 |
| ABHD18 | abhydrolase domain containing 18 | -0.00567485 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00567411 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.00564985 |
| ATP1A2 | ATPase, Na+/K+ transporting, alpha 2 polypeptide | -0.0056339 |
| KIF3B | kinesin family member 3B | -0.00562309 |
