GLI Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description GLI family zinc finger 1|This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] (NCBI Entrez Gene Database, 2735)
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Genes

46 target genes of the GLI transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
ADAR adenosine deaminase, RNA-specific
ADGRL3 adhesion G protein-coupled receptor L3
ADK adenosine kinase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CFC1B cripto, FRL-1, cryptic family 1B
CHD3 chromodomain helicase DNA binding protein 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTNAP1 contactin associated protein 1
CXXC5 CXXC finger protein 5
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNER delta/notch-like EGF repeat containing
ERF Ets2 repressor factor
EXTL3 exostosin-like glycosyltransferase 3
FAM110D family with sequence similarity 110, member D
FANCD2 Fanconi anemia, complementation group D2
FNDC1 fibronectin type III domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
FUBP3 far upstream element (FUSE) binding protein 3
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GLI1 GLI family zinc finger 1
GTF2IRD1 GTF2I repeat domain containing 1
HES1 hes family bHLH transcription factor 1
IRF9 interferon regulatory factor 9
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAP7D1 MAP7 domain containing 1
MIR593 microRNA 593
MIR873 microRNA 873
MIR96 microRNA 96
NARR nine-amino acid residue-repeats
NTN3 netrin 3
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
PRR3 proline rich 3
SH3BP1 SH3-domain binding protein 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOX8 SRY (sex determining region Y)-box 8
SP7 Sp7 transcription factor
SPATS1 spermatogenesis associated, serine-rich 1
SYNPO2 synaptopodin 2
TENM3 teneurin transmembrane protein 3
THADA thyroid adenoma associated
TLE4 transducin-like enhancer of split 4
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase
TSKU tsukushi, small leucine rich proteoglycan
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
ZNRF3 zinc and ring finger 3